Dr Alain Wuethrich
Dr

Alain Wuethrich

Email: 

Background

Dr Wuethrich is an NHMRC Emerging Leader fellow and ARC DECRA awardee at the Centre for Personalised Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland (UQ). Dr Wuethrich obtained his PhD from the University of Tasmania in 2016 after completing a Master’s degree in Switzerland. His research expertise lies in liquid biopsy, electrohydrodynamics, surface-enhanced Raman spectroscopy, nanotechnology and diagnostics. He held positions in international pharmaceutical companies and became lead inventor on a European patent. He has actively engaged with national and international companies to translate diagnostic nanotechnologies. Since 2017 he has provided continuous research mentoring to the group and has supervised >30 postgraduate and graduate students in nanotechnological strategies to detect cancer and other diseases.

Availability

Dr Alain Wuethrich is:
Available for supervision

Qualifications

  • Postgraduate Diploma, University of Tasmania
  • Doctor of Philosophy, University of Tasmania

Research interests

  • Liquid biopsy

  • Nanotechnology

  • Diagnostics

  • Electrohydrodynamics

  • Biosensing

Search Professor Alain Wuethrich’s works on UQ eSpace

83 works between 2013 and 2025
All (83) Journal Article (75) Book Chapter (6) Conference Publication (2)

61 - 80 of 83 works

2018

Journal Article

Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers

Wuethrich, Alain, Sina, Abu Ali Ibn, Ahmed, Mostak, Lin, Ting-Yun, Carrascosa, Laura G. and Trau, Matt (2018). Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers. Nanoscale, 10 (23), 10884-10890. doi: 10.1039/C7NR09496E

Interfacial nano-mixing in a miniaturised platform enables signal enhancement and in situ detection of cancer biomarkers

2018

Book Chapter

Capillary electrophoresis: overview

Quirino, Joselito P. and Wuethrich, Alain (2018). Capillary electrophoresis: overview. Reference module in chemistry, molecular sciences and chemical engineering. (pp. 1-32) edited by Jan Reedijk. Oxford, United Kingdom: Elsevier. doi: 10.1016/b978-0-12-409547-2.14461-0

Capillary electrophoresis: overview

2018

Journal Article

Derivatisation for separation and detection in capillary electrophoresis (2015–2017)

Wuethrich, Alain and Quirino, Joselito P. (2018). Derivatisation for separation and detection in capillary electrophoresis (2015–2017). Electrophoresis, 39 (1), 82-96. doi: 10.1002/elps.201700252

Derivatisation for separation and detection in capillary electrophoresis (2015–2017)

2018

Book Chapter

Stacking or On-line Sample Concentration in CE-MS for Metabolomics

Wuethrich, Alain and Quirino, Joselito P. (2018). Stacking or On-line Sample Concentration in CE-MS for Metabolomics. Capillary electrophoresis–mass spectrometry for metabolomics. (pp. 83-112) Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781788012737-00083

Stacking or On-line Sample Concentration in CE-MS for Metabolomics

2017

Journal Article

Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing

Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2017). Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing. Microchemical Journal, 137, 231-237. doi: 10.1016/j.microc.2017.10.012

Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing

2017

Journal Article

Electrophoretic concentration - a simple and green approach for sample preparation

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2017). Electrophoretic concentration - a simple and green approach for sample preparation. LCGC North America: solution for separation scientists, 35 (3), 197-201.

Electrophoretic concentration - a simple and green approach for sample preparation

2017

Journal Article

Sensitivity enhancing injection from a sample reservoir and channel interface in microchip electrophoresis

Wuethrich, Alain and Quirino, Joselito P. (2017). Sensitivity enhancing injection from a sample reservoir and channel interface in microchip electrophoresis. Journal of Separation Science, 40 (4), 927-932. doi: 10.1002/jssc.201601064

Sensitivity enhancing injection from a sample reservoir and channel interface in microchip electrophoresis

2017

Journal Article

Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2014–2016)

Breadmore, Michael C., Grochocki, Wojciech, Kalsoom, Umme, Alves, Mónica N., Phung, Sui Ching, Rokh, Masoomeh Tehrani, Cabot, Joan M., Ghiasvand, Alireza, Li, Feng, Shallan, Aliaa I., Keyon, Aemi S. Abdul, Alhusban, Ala A., See, Hong Heng, Wuethrich, Alain, Dawod, Mohamed and Quirino, Joselito P. (2017). Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2014–2016). Electrophoresis, 38 (1), 33-59. doi: 10.1002/elps.201600331

Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2014–2016)

2017

Book Chapter

Capillary Electrophoresis as a Green Alternative Separation Technique

Wuethrich, Alain and Quirino, Joselito P. (2017). Capillary Electrophoresis as a Green Alternative Separation Technique. The Application of Green Solvents in Separation Processes. (pp. 517-532) Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-0-12-805297-6.00017-6

Capillary Electrophoresis as a Green Alternative Separation Technique

2017

Journal Article

Electrophoretic concentration — a simple and green approach for sample preparation

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2017). Electrophoretic concentration — a simple and green approach for sample preparation. LC-GC Europe, 30 (2), 60-67.

Electrophoretic concentration — a simple and green approach for sample preparation

2016

Journal Article

Unusual stacking with electrokinetic injection of cationic analytes from micellar solutions in capillary zone electrophoresis

Wuethrich, Alain and Quirino, Joselito P. (2016). Unusual stacking with electrokinetic injection of cationic analytes from micellar solutions in capillary zone electrophoresis. Analytical and Bioanalytical Chemistry, 408 (30), 8663-8668. doi: 10.1007/s00216-016-9735-1

Unusual stacking with electrokinetic injection of cationic analytes from micellar solutions in capillary zone electrophoresis

2016

Journal Article

The electric field - an emerging driver in sample preparation

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2016). The electric field - an emerging driver in sample preparation. TrAC - Trends in Analytical Chemistry, 80, 604-611. doi: 10.1016/j.trac.2016.04.016

The electric field - an emerging driver in sample preparation

2016

Journal Article

Simultaneous electrophoretic concentration and separation of herbicides in beer prior to stacking capillary electrophoresis UV and liquid chromatography-mass spectrometry

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2016). Simultaneous electrophoretic concentration and separation of herbicides in beer prior to stacking capillary electrophoresis UV and liquid chromatography-mass spectrometry. Electrophoresis, 37 (9), 1122-1128. doi: 10.1002/elps.201600050

Simultaneous electrophoretic concentration and separation of herbicides in beer prior to stacking capillary electrophoresis UV and liquid chromatography-mass spectrometry

2016

Journal Article

Field-enhanced sample injection micelle-to-solvent stacking capillary zone electrophoresis-electrospray ionization mass spectrometry of antibiotics in seawater after solid-phase extraction: CE and CEC

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2016). Field-enhanced sample injection micelle-to-solvent stacking capillary zone electrophoresis-electrospray ionization mass spectrometry of antibiotics in seawater after solid-phase extraction: CE and CEC. Electrophoresis, 37 (9), 1139-1142. doi: 10.1002/elps.201500448

Field-enhanced sample injection micelle-to-solvent stacking capillary zone electrophoresis-electrospray ionization mass spectrometry of antibiotics in seawater after solid-phase extraction: CE and CEC

2016

Journal Article

Electrokinetic properties of lubricin antiadhesive coatings in microfluidic systems

Greene, George W., Duffy, Emer, Shallan, Aliaa, Wuethrich, Alain and Paull, Brett (2016). Electrokinetic properties of lubricin antiadhesive coatings in microfluidic systems. Langmuir, 32 (7), 1899-1908. doi: 10.1021/acs.langmuir.5b03535

Electrokinetic properties of lubricin antiadhesive coatings in microfluidic systems

2016

Journal Article

Derivatisation for separation and detection in capillary electrophoresis (2012-2015)

Wuethrich, Alain and Quirino, Joselito P. (2016). Derivatisation for separation and detection in capillary electrophoresis (2012-2015). Electrophoresis, 37 (1), 45-55. doi: 10.1002/elps.201500290

Derivatisation for separation and detection in capillary electrophoresis (2012-2015)

2015

Journal Article

Electrophoretic concentration and sweeping-micellar electrokinetic chromatography analysis of cationic drugs in water samples

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2015). Electrophoretic concentration and sweeping-micellar electrokinetic chromatography analysis of cationic drugs in water samples. Journal of Chromatography A, 1401, 84-88. doi: 10.1016/j.chroma.2015.05.018

Electrophoretic concentration and sweeping-micellar electrokinetic chromatography analysis of cationic drugs in water samples

2015

Journal Article

Green sample preparation for liquid chromatography and capillary electrophoresis of anionic and cationic analytes

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2015). Green sample preparation for liquid chromatography and capillary electrophoresis of anionic and cationic analytes. Analytical Chemistry, 87 (8), 4117-4123. doi: 10.1021/ac504765h

Green sample preparation for liquid chromatography and capillary electrophoresis of anionic and cationic analytes

2014

Journal Article

Off-line sample preparation by electrophoretic concentration using a micropipette and hydrogel

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2014). Off-line sample preparation by electrophoretic concentration using a micropipette and hydrogel. Journal of Chromatography A, 1369, 186-190. doi: 10.1016/j.chroma.2014.10.006

Off-line sample preparation by electrophoretic concentration using a micropipette and hydrogel

2014

Journal Article

Online sample concentration in partial-filling chiral electrokinetic chromatography - mass spectrometry

Wuethrich, Alain, Haddad, Paul R. and Quirino, Joselito P. (2014). Online sample concentration in partial-filling chiral electrokinetic chromatography - mass spectrometry. Chirality, 26 (11), 734-738. doi: 10.1002/chir.22257

Online sample concentration in partial-filling chiral electrokinetic chromatography - mass spectrometry

Current funding

  • 2025 - 2029
    Immune Dashboard Chip (IDC): Single-molecule digital nanotechnology for profiling trace immune dysregulations in Long COVID-19 and improving mRNA vaccines
    NHMRC Investigator Grants
    Open grant
  • 2025
    Nanoscale profiling of immune overreactions in cancer therapy, infectious and autoimmune diseases
    UQ Foundation Research Excellence Awards
    Open grant
  • 2024 - 2026
    ALL IN - AI and Laboratory Led IdentificatioN of PASC
    NHMRC MRFF Post-Acute Sequelae of COVID-19
    Open grant
  • 2024 - 2025
    A blood-based nanotechnology to decipher the extracellular vesicle code in ALS
    Motor Neurone Disease Research Institute of Australia Inc Innovator Grant
    Open grant
  • 2023 - 2027
    Rhythms and blues: Personalising care for body clock dysfunction in mood disorders (NHMRC Synergy grant administered by University of Sydney)
    University of Sydney
    Open grant

Past funding

  • 2022 - 2025
    nanoIMPAC: Monitoring immune toxicities and tumour immune evasion in lung cancer
    Cancer Australia
    Open grant
  • 2021 - 2023
    Single molecule sensing on nanopillars: Reading complex molecular circuits
    ARC Discovery Projects
    Open grant
  • 2020 - 2024
    A protein phosphorylation mapping tool for monitoring tyrosine kinase inhibition therapy in cancer patients
    NHMRC Investigator Grants
    Open grant
  • 2020
    Harnessing nanotechnology to unravel extracellular vesicle heterogeneity
    ARC Discovery Early Career Researcher Award
    Open grant
  • 2019
    Towards personalized nanomedicine: Exploring interfacial nanomixing as a tool to monitor aberrant protein phosphorylation pathways in cancer
    UQ Early Career Researcher
    Open grant
  • 2018 - 2019
    Enhanced electrochemical biosensing through electrohydrodynamic nanofluidics for cancer diagnostics
    UQ Development Fellowships
    Open grant

Availability

Dr Alain Wuethrich is:
Available for supervision

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Available projects

Supervision history

Current supervision

Completed supervision

Enquiries

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