
Overview
Background
Michael (Mike) Roberts is a NHMRC Senior Principal Research Fellow and Emeritus Professor of Clinical Pharmacology & Therapeutics and Director of the Therapeutics Research Centre in the Diamantina Institute at The University of Queensland, which is based in the Translational Research Institute adjacent to the Princess Alexandra Hospital in Brisbane, Qld, Australia. He is also Professor of Therapeutics & Pharmaceutical Science at the University of South Australia with laboratories in the Basil Hetzel Institute at The Queen Elizabeth Hospital in Adelaide, South Australia.
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Pharmacy, University of Adelaide
- Masters (Coursework) of Science, University of Sydney
- Doctor of Philosophy, University of Sydney
- Masters (Coursework) of Business Administration, The University of Queensland
- Doctoral Diploma of Science (Advanced), University of Sydney
Works
Search Professor Michael Roberts’s works on UQ eSpace
2012
Journal Article
The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis
Liu, Xin, Kruger, Peter S., Weiss, Michael and Roberts, Michael S. (2012). The pharmacokinetics and pharmacodynamics of cisatracurium in critically ill patients with severe sepsis. British Journal of Clinical Pharmacology, 73 (5), 741-749. doi: 10.1111/j.1365-2125.2011.04149.x
2012
Journal Article
Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study
Roberts, Darren M., Roberts, Jason A., Roberts, Michael S., Liu, Xin, Nair, Priya, Cole, Louise, Lipman, Jeffrey, Bellomo, Rinaldo and on behalf of the RENAL Replacement Therapy Study Investigators (2012). Variability of antibiotic concentrations in critically ill patients receiving continuous renal replacement therapy: A multicentre pharmacokinetic study. Critical Care Medicine, 40 (5), 1523-1528. doi: 10.1097/CCM.0b013e318241e553
2012
Journal Article
Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application
Dancik, Yuri, Anissimov, Yuri G., Jepps, Owen G. and Roberts, Michael S. (2012). Convective transport of highly plasma protein bound drugs facilitates direct penetration into deep tissues after topical application. British Journal of Clinical Pharmacology, 73 (4), 564-578. doi: 10.1111/j.1365-2125.2011.04128.x
2012
Journal Article
Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection
Mahmood, Adnan H., Medley, Gregory A., Grice, Jeffrey E., Liu, Xin and Roberts, Michael S. (2012). Determination of trovafloxacin and marbofloxacin in sheep plasma samples by HPLC using UV detection. Journal of Pharmaceutical and Biomedical Analysis, 62, 220-223. doi: 10.1016/j.jpba.2012.01.007
2012
Journal Article
Quantum dot penetration into viable human skin
Prow, Tarl W., Monteiro-Riviere, Nancy A., Inman, Alfred O., Grice, Jeffrey E., Chen, Xianfeng, Zhao, Xin, Sanchez, Washington H., Gierden, Audrey, Kendall, Mark A. F., Zvyagin, Andrei V., Erdmann, Detlev, Rivierer, Jim E. and Roberts, Michael S. (2012). Quantum dot penetration into viable human skin. Nanotoxicology, 6 (2), 173-185. doi: 10.3109/17435390.2011.569092
2012
Journal Article
Continuation of Statin Therapy in patients with presumed infection
Kruger, Peter S., Joyce, Christopher J., Harward, Meg L., Jones, Mark A., Kostner, Karam M., Roberts, Michael S. and Venkatesh, Bala (2012). Continuation of Statin Therapy in patients with presumed infection. American Journal of Respiratory and Critical Care Medicine, 185 (4), 456-457. doi: 10.1164/ajrccm.185.4.456a
2012
Journal Article
The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences
Liu, David C., Raphael, Anthony P., Sundh, Daniel, Grice, Jeffrey E., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2012). The human stratum corneum prevents small gold nanoparticle penetration and their potential toxic metabolic consequences. Journal of Nanomaterials, 2012 (1) 721706, 72176.1-72176.8. doi: 10.1155/2012/721706
2012
Journal Article
Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review
Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2012). Using pharmacokinetics and pharmacodynamics to optimise dosing of antifungal agents in critically ill patients: A systematic review. International Journal of Antimicrobial Agents, 39 (1), 1-10. doi: 10.1016/j.ijantimicag.2011.07.013
2012
Book Chapter
Electrical and physical methods of skin penetration enhancement
Grice, Jeffrey E., Prow, Tarl W., Kendall, Mark A. F. and Roberts, Michael S. (2012). Electrical and physical methods of skin penetration enhancement. Topical and transdermal drug delivery: Principles and practice. (pp. 43-65) edited by Heather A. E. Benson and Adam C. Watkinson. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781118140505.ch3
2012
Conference Publication
Removing nanoparticles from human skin
Lin, L. L., Sundh, D., Raphael, A. P., Roberts, M. S., Soyer, H. and Prow, T. W. (2012). Removing nanoparticles from human skin. Conjoint 3rd Australasian Wound & Tissue Repair Society and 9th Australasian Society for Dermatology Research Conference, Sydney, NSW, Australia, 22-24 May 2012. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/j.1524-475X.2012.00835.x
2011
Journal Article
Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport
Song, Zhen, Kelf, Timothy A., Sanchez, Washington H., Roberts, Michael S., Ricka, Jaro, Frenz, Martin and Zvyagin, Andrei V. (2011). Characterization of optical properties of ZnO nanoparticles for quantitative imaging of transdermal transport. Biomedical Optics Express, 2 (12), 3321-3333. doi: 10.1364/BOE.2.003321
2011
Journal Article
Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats
Thorling, Camilla A., Liu, Xin, Burczynski, Frank J., Fletcher, Linda M., Gobe, Glenda C. and Roberts, Michael S. (2011). Multiphoton microscopy can visualize zonal damage and decreased cellular metabolic activity in hepatic ischemia-reperfusion injury in rats. Journal of Biomedical Optics, 16 (11) 116011, 116011-1160118. doi: 10.1117/1.3647597
2011
Journal Article
Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin
Lin, Lynlee L., Grice, Jeffrey E., Butler, Margaret K., Zvyagin, Andrei V., Becker, Wolfgang, Robertson, Thomas A., Soyer, H. Peter, Roberts, Michael S. and Prow, Tarl W. (2011). Time-correlated single photon counting for simultaneous monitoring Of zinc oxide nanoparticles and NAD(P)H in intact and barrier-disrupted volunteer skin. Pharmaceutical Research, 28 (11), 2920-2930. doi: 10.1007/s11095-011-0515-5
2011
Journal Article
Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man
Liu, Xin, Grice, Jeff E., Lademann, Juergen, Otberg, Nina, Trauer, Sindy, Patzelt, Alexa and Roberts, Michael S. (2011). Hair follicles contribute significantly to penetration through human skin only at times soon after application as a solvent deposited solid in man. British Journal of Clinical Pharmacology, 72 (5), 768-774. doi: 10.1111/j.1365-2125.2011.04022.x
2011
Journal Article
Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery
Douglas, Alexandra, Udy, Andrew A., Wallis, Steven C., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Deans, Renae, Roberts, Michael S., Taraporewalla, Kersi, Jenkins, Jason, Medley, Gregory, Lipman, Jeffrey and Roberts, Jason A. (2011). Plasma and tissue pharmacokinetics of cefazolin in patients undergoing elective and semielective abdominal aortic aneurysm open repair surgery. Antimicrobial Agents and Chemotherapy, 55 (11), 5238-5242. doi: 10.1128/AAC.05033-11
2011
Journal Article
Pharmacokinetic evaluation of fluconazole in critically ill patients
Sinnollareddy, Mahipal, Peake, Sandra L., Roberts, Michael S., Playford, E. Geoffrey, Lipman, Jeffrey and Roberts, Jason A. (2011). Pharmacokinetic evaluation of fluconazole in critically ill patients. Expert Opinion On Drug Metabolism and Toxicology, 7 (11), 1431-1440. doi: 10.1517/17425255.2011.615309
2011
Journal Article
Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies
Wunnapuk, Klintean, Medley, Gregory A., Liu, Xin, Grice, Jeffrey E., Jayasinghe, Sudheera, Gawarammana, Indika, Buckley, Nicholas A. and Roberts, Michael S. (2011). Simple and sensitive liquid chromatography-tandem mass spectrometry methods for quantification of paraquat in plasma and urine: Application to experimental and clinical toxicological studies. Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences, 879 (28), 3047-3052. doi: 10.1016/j.jchromb.2011.09.008
2011
Journal Article
Mathematical models of skin permeability: An overview
Mitragotri, Samir, Anissimov, Yuri G., Bunge, Annette L., Frasch, H. Frederick, Guy, Richard H., Hadgraft, Jonathan, Kasting, Gerald B., Lane, Majella E. and Roberts, Michael S. (2011). Mathematical models of skin permeability: An overview. International Journal of Pharmaceutics, 418 (1), 115-129. doi: 10.1016/j.ijpharm.2011.02.023
2011
Journal Article
Modelling dermal drug distribution after topical application in human
Anissimov, Yuri G. and Roberts, Michael Stephen (2011). Modelling dermal drug distribution after topical application in human. Pharmaceutical Research, 28 (9), 2119-2129. doi: 10.1007/s11095-011-0437-2
2011
Journal Article
Gold nanoparticle penetration and reduced metabolism in human skin by toluene
Labouta, H. I., Liu, D. C., Lin, L. L., Butler, M. K., Grice, J. E., Raphael, A. P., Kraus, T., El-Khordagui, L. K., Soyer, H. P., Roberts, M. S., Schneider, M. and Prow, T. W. (2011). Gold nanoparticle penetration and reduced metabolism in human skin by toluene. Pharmaceutical Research, 28 (11), 2931-2944. doi: 10.1007/s11095-011-0561-z
Funding
Current funding
Past funding
Supervision
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Injection of Supercritical and Near-Critical Fluids into Supersonic Crossflow
Associate Advisor
Other advisors: Dr Tristan Vanyai, Professor Anand Veeraragavan
-
Doctor Philosophy
Injection of Supercritical Ethylene into Supersonic Combustor Crossflow
Associate Advisor
Other advisors: Dr Tristan Vanyai, Professor Anand Veeraragavan
Completed supervision
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2023
Doctor Philosophy
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
Principal Advisor
Other advisors: Dr Xin Liu, Dr Haolu Wang
-
2022
Doctor Philosophy
Pharmacotherapy consideration in hospitalized older diabetic and cardiovascular disease patients aged 75 years and above with polypharmacy
Principal Advisor
Other advisors: Dr Xin Liu, Dr Xiaowen Liang
-
2021
Doctor Philosophy
Modeling approaches to predict human skin absorption of drugs and other chemicals
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2019
Doctor Philosophy
Development of optimal experimental conditions for evaluation of topical products
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2017
Doctor Philosophy
Embedding the Clinician-Researcher Pharmacist in Healthcare
Principal Advisor
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
Biodistribution of newly developed water-dispersible CdTe/CdS quantum dots for in vivo imaging
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Pharmacokinetics, Pharmacodynamics and Safety of Marbofloxacin and Trovafloxacin in Sheep
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Herbicide nephrotoxicity in rat and human
Principal Advisor
Other advisors: Dr Xin Liu
-
2013
Doctor Philosophy
Statin Therapy in Patients with Sepsis: From Retrospective Analysis to RCT
Principal Advisor
-
2011
Doctor Philosophy
Drug Disposition in Liver Disease: Liver histopathology and hepatic drug transporter activity as determinants of drug disposition in liver diseases
Principal Advisor
Other advisors: Dr Xin Liu
-
2010
Doctor Philosophy
The effect of resuscitation fluids on beta lactam antibiotic pharamacokinetics in interstitial tissue in acute thermal injury
Principal Advisor
Other advisors: Professor Bala Venkatesh
-
-
2006
Master Philosophy
IONTOPHORESIS OF THE NAIL
Principal Advisor
-
2006
Doctor Philosophy
AXOPLASMIC TRANSPORT AND TRANSEPIDERMAL IONTOPHORESIS: FACTORS IN NEUROGENIC PAIN MANAGEMENT
Principal Advisor
-
2005
Master Philosophy
PERCUTANEOUS PENETRATION OF PARABENS THROUGH HUMAN EPDIERMAL MEMBRANE
Principal Advisor
-
2005
Doctor Philosophy
DISPOSITION PHARMACOKINETICS AND EFFECTS OF SOLUTES AND DRUGS IN PERFUSED ORGAN SYSTEMS
Principal Advisor
-
2004
Doctor Philosophy
MEDICATION CARE: DATABASES, DRUG USE AND OUTCOMES
Principal Advisor
-
2004
Doctor Philosophy
PHARMACOEPIDEMIOLOGY OF MEDICATION USE BY THE COMMUNITY-BASED ELDERLY
Principal Advisor
-
2003
Doctor Philosophy
A COMPARISON OF THE APPROPRIATENESS OF PSYCHOTROPIC DRUG AND POLYPHARMACY USE IN MENTAL HEALTH, IN INSTITUTIONALISED PATIENTS AND IN THE COMMUNITY
Principal Advisor
-
2003
Doctor Philosophy
QUALITY OF MEDICATION CARE IN LONG TERM CARE FACILITIES: ASSESSMENT OF PROCESS, NEEDS AND TYPE OF INTERVENTION
Principal Advisor
-
2002
Doctor Philosophy
THE STUDIES OF ALCOHOLIC LIVER DISEASE (ALD): PATHOGENESIS, PHARMACOKINETICS AND THERAPEUTIC APPROACHES
Principal Advisor
-
2002
Doctor Philosophy
IDENTIFICATION AND PURIFICATION OF THE JOINT SURFACTANT PROTEINS
Principal Advisor
-
2002
Doctor Philosophy
THE EFFECT OF CHEMICAL STRUCTURE ON THE ABSORPTION OF SUNSCREENS THROUGH THE SKIN
Principal Advisor
-
2023
Doctor Philosophy
Human mesenchymal stem cell-derived liver-on-a-chip for the study of cell migration
Associate Advisor
Other advisors: Dr Kim Bridle, Dr Xiaowen Liang, Dr Haolu Wang
-
2022
Doctor Philosophy
The Characterisation of Tumour Self-Seeded Cells in Liver Cancer
Associate Advisor
Other advisors: Dr Haolu Wang, Dr Xiaowen Liang
-
2020
Doctor Philosophy
Enhanced topical drug delivery for treatment of human melanoma
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard, Associate Professor Yousuf Mohammed, Associate Professor Helmut Schaider
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2019
Doctor Philosophy
Evaluation of a Ketogenic Formulation for Treating Patients with Acute Brain Injury
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2017
Doctor Philosophy
Real-time optical imaging of the liver: diagnosis and prediction of treatment response
Associate Advisor
Other advisors: Dr Xin Liu
-
2016
Doctor Philosophy
EFFECT OF TOPICAL MAGNESIUM APPLICATION ON EPIDERMAL INTEGRITY AND BARRIER FUNCTION
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard
-
2016
Doctor Philosophy
Targeted skin delivery of topically applied drugs by optimised formulation design
Associate Advisor
Other advisors: Dr Xin Liu
-
2014
Master Philosophy
Development of a soluble macrolide formulation and identification of potential benefits in chronic rhinosinusitis.
Associate Advisor
-
2013
Doctor Philosophy
Particulate Penetration and Metabolic Effects in Human Skin
Associate Advisor
-
2009
Doctor Philosophy
Beta-lactam antibiotic dosing in critical care units: Bolus vs continuous dosing
Associate Advisor
Other advisors: Professor Jeffrey Lipman
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2008
Doctor Philosophy
Depression in Parkinson's disease: assessment methods and risk factors
Associate Advisor
Other advisors: Associate Professor John O'Sullivan
-
2005
Doctor Philosophy
SURFACTANT PROTEINS IN EXTRA PULMONARY SITES
Associate Advisor
Media
Enquiries
Contact Emeritus Professor Michael Roberts directly for media enquiries about:
- Clinical pharmacology
- Drug analysis
- Drug delivery - pharmacology
- Drug structure-disposition relationships
- Health care delivery
- Hepatic metabolism
- Medication care
- Pharmacokinetics
- Pharmacology
- Topical (skin) products
- Toxicology - drugs
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