
Overview
Background
Michael (Mike) Roberts is a NHMRC Senior Principal Research Fellow and Emeritus Professor of Clinical Pharmacology & Therapeutics and Director of the Therapeutics Research Centre in the Diamantina Institute at The University of Queensland, which is based in the Translational Research Institute adjacent to the Princess Alexandra Hospital in Brisbane, Qld, Australia. He is also Professor of Therapeutics & Pharmaceutical Science at the University of South Australia with laboratories in the Basil Hetzel Institute at The Queen Elizabeth Hospital in Adelaide, South Australia.
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Pharmacy, University of Adelaide
- Masters (Coursework) of Science, University of Sydney
- Doctor of Philosophy, University of Sydney
- Masters (Coursework) of Business Administration, The University of Queensland
- Doctoral Diploma of Science (Advanced), University of Sydney
Works
Search Professor Michael Roberts’s works on UQ eSpace
2010
Journal Article
Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2
Liu, Xin, Yang, Yan, Zhang, Xiaoxiang, Xu, Shengxin, He, Shufang, Huang, Weijuan and Roberts, Michael S. (2010). Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-beta/Smad in HepG2. Journal of Gastroenterology and Hepatology, 25 (2), 420-426. doi: 10.1111/j.1440-1746.2009.05981.x
2010
Journal Article
First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis
Roberts, Jason A., Kirkpatrick, Carl M. J., Roberts, Michael S., Dalley, Andrew J. and Lipman, Jeffrey (2010). First-dose and steady-state population pharmacokinetics and pharmacodynamics of piperacillin by continuous or intermittent dosing in critically ill patients with sepsis. International Journal of Antimicrobial Agents, 35 (2), 156-163. doi: 10.1016/j.ijantimicag.2009.10.008
2010
Journal Article
Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro
Grice, Jeffrey E., Ciotti, Susan, Weiner, Norman, Lockwood, Peter, Cross, Sheree E. and Roberts, Michael S. (2010). Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro. Journal of Pharmaceutical Sciences, 99 (2), 712-718. doi: 10.1002/jps.21856
2010
Conference Publication
Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients
Roberts, D., Roberts, M., Liu, X., Roberts, J., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ANZSN 2010: 46th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Perth, WA, Australia, 12-15 September 2010. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/j.1440-1797.2010.01377_1.x
2010
Journal Article
Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model
Zou, Yu-Hong, Liu, Xin, Khlentzos, Alexander M., Asadian, Peyman, Li, Peng, Thorling, Camilla A., Robertson, Thomas A., Fletcher, Linda M., Crawford, Darrell H. G. and Roberts, Michael S. (2010). Liver fibrosis impairs hepatic pharmacokinetics of liver transplant drugs in the rat model. Drug Metabolism and Pharmacokinetics, 25 (5), 442-449. doi: 10.2133/dmpk.DMPK-10-RG-031
2010
Book Chapter
Cutaneous metabolism and active transport in transdermal drug delivery
Dancik, Yuri, Thompson, Camilla, Krishnan, Gayathri and Roberts, Michael S. (2010). Cutaneous metabolism and active transport in transdermal drug delivery. Toxicology of the skin. (pp. 69-82) edited by Nancy A. Monteiro-Riviere, A. Wallace Hayes, John A. Thomas and Donald E. Gardner. New York , NY, U.S.A.: Informa Healthcare USA.
2010
Conference Publication
Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients
Roberts, D. M., Roberts, M. S., Liu, X., Roberts, J. A., Lipman, J. and Bellomo, R. (2010). Clearance of antibiotics by high and low intensity continuous renal replacement therapy in critically ill patients. ESICM 2010: 23rd Annual Meeting of the European Society of Intensive Care Medicine, Barcelona, Spain, 9-13 October, 2010. Heidelberg, Germany: Springer. doi: 10.1007/s00134-010-1999-x
2010
Journal Article
Skin abrasion: Transdermal delivery, cosmetic and immunological applications
Grice, J. E. and Roberts, M. S. (2010). Skin abrasion: Transdermal delivery, cosmetic and immunological applications. Transdermal, 2 (1), 11-16.
2010
Journal Article
Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model
Fernando, Germain J. P., Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Fairmaid, Emily J., Roberts, Michael S., Frazer, Ian H., Brown, Lorena E. and Kendall, Mark A. F. (2010). Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model. PLoS One, 5 (4) e10266, e10266.1-e10266.11. doi: 10.1371/journal.pone.0010266
2010
Conference Publication
Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in viable epidermis of ex-vivo human skin
Geusens, B., Van Gele, M., Braat, S., De Smedt, S. C., Stuart, M. C. A., Prow, T., Sanchez, W., Roberts, M. S., Sanders, N. N. and Lambert, J. (2010). Flexible nanosomes (SECosomes) enable efficient siRNA delivery in cultured primary skin cells and in viable epidermis of ex-vivo human skin. 12th International Conference Perspectives in Percutaneous Penetration, La Grande Motte, France, 7‐10 April, 2010. Oxford, United Kingdom: John Wiley & Sons.
2010
Conference Publication
ZnO and TiO(2) particles: a study on nanosafety and photoprotection
Popov, Alexey, Zhao, Xin, Zvyagin, Andrei, Lademann, Jürgen, Roberts, Michael, Sanchez, Washington, Priezzhev, Alexander and Myllylä, Risto (2010). ZnO and TiO(2) particles: a study on nanosafety and photoprotection. SPIE Photonics Europe 2010. Biophotonics: Photonic Solutions for Better Health Care, Brussels, Belgium, 12-16 April, 2010. Bellingham, WA, United States: S P I E - International Society for Optical Engineering. doi: 10.1117/12.854561
2010
Book Chapter
Chemical structure-skin transport relationships
Grice, Jeffrey E., Zhang, Qian and Roberts, Michael S. (2010). Chemical structure-skin transport relationships. Toxicology of the skin. (pp. 55-68) edited by Nancy A. Monteiro-Riviere. New York , NY, U.S.A.: Informa Healthcare USA. doi: 10.3109/9781420079180
2009
Journal Article
Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Jenkins, Derek W.K., Roberts, Michael S., Frazer, Ian H., Fernando, Germain J.P. and Kendall, Mark A.F. (2009). Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. Journal of Controlled Release, 139 (3), 212-220. doi: 10.1016/j.jconrel.2009.06.029
2009
Journal Article
Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments
Mutalik, S., Hewavitharana, A., Shaw, P. N., Anissimov, Y. G., Roberts, M. S. and Parekh, H. S. (2009). Development and validation of a reversed-phase high-performance liquid chromatographic method for quantification of peptide dendrimers in human skin permeation experiments. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 877 (29), 3556-3562. doi: 10.1016/j.jchromb.2009.08.039
2009
Journal Article
Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets
Monajjemzadeh, Farnaz, Hassanzadeh, Davoud, Valizadeh, Hadi, Siahi-Shadbad, Mohammad R., Mojarrad, Javid Shahbazi, Robertson, Thomas A. and Roberts, Michael S. (2009). Compatibility studies of acyclovir and lactose in physical mixtures and commercial tablets. European Journal of Pharmaceutics and Biopharmaceutics, 73 (3), 404-413. doi: 10.1016/j.ejpb.2009.06.012
2009
Journal Article
Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers
Dalley, A.J., Lipman, J., Deans, R., Venkatesh, B., Rudd, M., Roberts, M.S. and Cross, S.E. (2009). Tissue accumulation of cephalothin in burns: A comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers. Antimicrobial Agents and Chemotherapy, 53 (1), 210-215. doi: 10.1128/AAC.00718-08
2009
Journal Article
Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats
Xia, C.H., Sun, J.G., Wang, G.J., Shang, L.L., Zhang, X.X., Zhang, R., Peng, Y., Wang, X.J., Hao, H.P., Xie, L. and Roberts, M.S. (2009). Herb-Drug interactions: In vivo and in vitro effect of shenmai injection, a herbal preparation, on the metabolic activities of hepatic cytochrome P450 3A1/2, 2C6, 1A2, and 2E1 in Rats. Planta Medica: natural products and medicinal plant research, 76 (3), 245-250. doi: 10.1055/s-0029-1186082
2009
Journal Article
Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver
Fanning, Kent J., Anissimov, Yuri G. and Roberts, Michael S. (2009). Sulphonylurea physiochemical-pharmacokinetic relationships in the pancreas and liver. Journal of Pharmaceutical Sciences, 98 (8), 2807-2821. doi: 10.1002/jps.21631
2009
Journal Article
Skin solubility determines maximum transepidermal flux for similar size molecules
Zhang, Qian, Grice, Jeffrey E., Li, Peng, Jepps, Owen G., Wang, Guang-Ji and Roberts, Michael S. (2009). Skin solubility determines maximum transepidermal flux for similar size molecules. Pharmaceutical Research, 26 (8), 1974-1985. doi: 10.1007/s11095-009-9912-4
2009
Journal Article
Liver transporters in hepatic drug disposition: An update
Li, Peng, Wang, Guang-Ji, Robertson, Thomas A. and Roberts, Michael S. (2009). Liver transporters in hepatic drug disposition: An update. Current Drug Metabolism, 10 (5), 482-498. doi: 10.2174/138920009788898037
Funding
Current funding
Past funding
Supervision
Availability
- Emeritus Professor Michael Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Injection of Supercritical Ethylene into Supersonic Combustor Crossflow
Associate Advisor
Other advisors: Dr Tristan Vanyai, Professor Anand Veeraragavan
-
Doctor Philosophy
Injection of Supercritical and Near-Critical Fluids into Supersonic Crossflow
Associate Advisor
Other advisors: Dr Tristan Vanyai, Professor Anand Veeraragavan
Completed supervision
-
2023
Doctor Philosophy
Development of artificial mesenchymal stem cells for hepatocellular carcinoma drug delivery
Principal Advisor
Other advisors: Dr Xin Liu, Dr Haolu Wang
-
2022
Doctor Philosophy
Pharmacotherapy consideration in hospitalized older diabetic and cardiovascular disease patients aged 75 years and above with polypharmacy
Principal Advisor
Other advisors: Dr Xin Liu, Dr Xiaowen Liang
-
2021
Doctor Philosophy
Modeling approaches to predict human skin absorption of drugs and other chemicals
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2019
Doctor Philosophy
Development of optimal experimental conditions for evaluation of topical products
Principal Advisor
Other advisors: Associate Professor Yousuf Mohammed, Dr Xin Liu
-
2017
Doctor Philosophy
Embedding the Clinician-Researcher Pharmacist in Healthcare
Principal Advisor
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Principal Advisor
Other advisors: Professor Jason Roberts, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
Biodistribution of newly developed water-dispersible CdTe/CdS quantum dots for in vivo imaging
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Pharmacokinetics, Pharmacodynamics and Safety of Marbofloxacin and Trovafloxacin in Sheep
Principal Advisor
Other advisors: Dr Xin Liu
-
2014
Doctor Philosophy
Herbicide nephrotoxicity in rat and human
Principal Advisor
Other advisors: Dr Xin Liu
-
2013
Doctor Philosophy
Statin Therapy in Patients with Sepsis: From Retrospective Analysis to RCT
Principal Advisor
-
2011
Doctor Philosophy
Drug Disposition in Liver Disease: Liver histopathology and hepatic drug transporter activity as determinants of drug disposition in liver diseases
Principal Advisor
Other advisors: Dr Xin Liu
-
2010
Doctor Philosophy
The effect of resuscitation fluids on beta lactam antibiotic pharamacokinetics in interstitial tissue in acute thermal injury
Principal Advisor
Other advisors: Professor Bala Venkatesh
-
-
2006
Master Philosophy
IONTOPHORESIS OF THE NAIL
Principal Advisor
-
2006
Doctor Philosophy
AXOPLASMIC TRANSPORT AND TRANSEPIDERMAL IONTOPHORESIS: FACTORS IN NEUROGENIC PAIN MANAGEMENT
Principal Advisor
-
2005
Master Philosophy
PERCUTANEOUS PENETRATION OF PARABENS THROUGH HUMAN EPDIERMAL MEMBRANE
Principal Advisor
-
2005
Doctor Philosophy
DISPOSITION PHARMACOKINETICS AND EFFECTS OF SOLUTES AND DRUGS IN PERFUSED ORGAN SYSTEMS
Principal Advisor
-
2004
Doctor Philosophy
MEDICATION CARE: DATABASES, DRUG USE AND OUTCOMES
Principal Advisor
-
2004
Doctor Philosophy
PHARMACOEPIDEMIOLOGY OF MEDICATION USE BY THE COMMUNITY-BASED ELDERLY
Principal Advisor
-
2003
Doctor Philosophy
A COMPARISON OF THE APPROPRIATENESS OF PSYCHOTROPIC DRUG AND POLYPHARMACY USE IN MENTAL HEALTH, IN INSTITUTIONALISED PATIENTS AND IN THE COMMUNITY
Principal Advisor
-
2003
Doctor Philosophy
QUALITY OF MEDICATION CARE IN LONG TERM CARE FACILITIES: ASSESSMENT OF PROCESS, NEEDS AND TYPE OF INTERVENTION
Principal Advisor
-
2002
Doctor Philosophy
THE STUDIES OF ALCOHOLIC LIVER DISEASE (ALD): PATHOGENESIS, PHARMACOKINETICS AND THERAPEUTIC APPROACHES
Principal Advisor
-
2002
Doctor Philosophy
IDENTIFICATION AND PURIFICATION OF THE JOINT SURFACTANT PROTEINS
Principal Advisor
-
2002
Doctor Philosophy
THE EFFECT OF CHEMICAL STRUCTURE ON THE ABSORPTION OF SUNSCREENS THROUGH THE SKIN
Principal Advisor
-
2023
Doctor Philosophy
Human mesenchymal stem cell-derived liver-on-a-chip for the study of cell migration
Associate Advisor
Other advisors: Dr Kim Bridle, Dr Xiaowen Liang, Dr Haolu Wang
-
2022
Doctor Philosophy
The Characterisation of Tumour Self-Seeded Cells in Liver Cancer
Associate Advisor
Other advisors: Dr Haolu Wang, Dr Xiaowen Liang
-
2020
Doctor Philosophy
Enhanced topical drug delivery for treatment of human melanoma
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard, Associate Professor Yousuf Mohammed, Associate Professor Helmut Schaider
-
2019
Doctor Philosophy
Evaluation of a Ketogenic Formulation for Treating Patients with Acute Brain Injury
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2017
Doctor Philosophy
Real-time optical imaging of the liver: diagnosis and prediction of treatment response
Associate Advisor
Other advisors: Dr Xin Liu
-
2016
Doctor Philosophy
EFFECT OF TOPICAL MAGNESIUM APPLICATION ON EPIDERMAL INTEGRITY AND BARRIER FUNCTION
Associate Advisor
Other advisors: Emeritus Professor Ross Barnard
-
2016
Doctor Philosophy
Targeted skin delivery of topically applied drugs by optimised formulation design
Associate Advisor
Other advisors: Dr Xin Liu
-
2014
Master Philosophy
Development of a soluble macrolide formulation and identification of potential benefits in chronic rhinosinusitis.
Associate Advisor
-
2013
Doctor Philosophy
Particulate Penetration and Metabolic Effects in Human Skin
Associate Advisor
-
2009
Doctor Philosophy
Beta-lactam antibiotic dosing in critical care units: Bolus vs continuous dosing
Associate Advisor
Other advisors: Professor Jeffrey Lipman
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2008
Doctor Philosophy
Depression in Parkinson's disease: assessment methods and risk factors
Associate Advisor
Other advisors: Associate Professor John O'Sullivan
-
2005
Doctor Philosophy
SURFACTANT PROTEINS IN EXTRA PULMONARY SITES
Associate Advisor
Media
Enquiries
Contact Emeritus Professor Michael Roberts directly for media enquiries about:
- Clinical pharmacology
- Drug analysis
- Drug delivery - pharmacology
- Drug structure-disposition relationships
- Health care delivery
- Hepatic metabolism
- Medication care
- Pharmacokinetics
- Pharmacology
- Topical (skin) products
- Toxicology - drugs
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