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Professor Dan Siskind
Professor

Dan Siskind

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Overview

Background

Prof Siskind trained as a psychiatrist in Australia and the United States. He graduated from medicine at the University of Queensland in 1998. After working with Doctors Without Borders in Chechnya in 2000, he became interested in psychiatry. He moved to Boston in 2002, where he did his psychiatry residency at Boston University and a Master of Public Health at Harvard University. He returned to Brisbane in June 2008 as a clinical academic psychiatrist at the Metro South Addiction and Mental Health Service. He completed his Ph.D in Feb 2014. His research interests include clozapine and treatment refractory schizophrenia, the physical health of people with severe and persistent mental illness, supported accommodation, assertive community treatment and mental health services research. He was awarded an NHMRC Investigator Grant as a Leadership Fellow (L1 2027-2031) an Emerging Leadership Fellow (EL2 2021-2025) and an NHMRC Early Career Fellowship (ECF 2016-2019). He has a current CIA MRFF RCRDUN grant looking at treatments to reduce cardiometabolic morbidity among people with schizophrenia. He was the SIRS 2026 Outstanding Clinical and Community Research Award recipient, and was elected to the Australian Academy of Health and Medical Sciences in 2025. He has over 350 peer reviewed publications, including first author in the highly ranked Lancet, World Psychiatry, Lancet Psychiatry, BJPsych, ANZJP, & Schizophrenia Bulletin. He is a named investigator on over $65 million in competitive research grants, with over $9 million as CIA.

Availability

Professor Dan Siskind is:
Available for supervision
Media expert

Fields of research

Research interests

  • Schizophrenia

  • Physical Health Comorbidity

Research impacts

Prof Siskind's research has had direct, measurable impact on clinical practice and policy. His landmark studies on clozapine-associated neutropenia demonstrated that routine monitoring could safely cease after two years, evidence that has driven the removal of long-term monitoring mandates by regulators — improving safe and quality access to clozapine for more than 2.5 million people globally. His work establishing optimal plasma clozapine reference ranges is now used by pathology providers across Australia, while his findings on antipsychotic-associated metabolic risk and weight gain have been incorporated into international guidelines and adopted into clinical practice, with metformin augmentation now regularly prescribed for patients commencing antipsychotics. His Lancet Psychiatry Commission on physical health in people with mental illness helped set the global agenda for integrating physical and mental healthcare, informing policy from the WHO, OECD, and across multiple countries. As Chair of the INTEGRATE Steering Committee, he led development of the first consensus-based, algorithmic international guidelines for schizophrenia treatment, which have been endorsed by peak bodies. Through sustained engagement with regulators, professional colleges and health services, Prof Siskind has ensured his research translates rapidly from bench to bedside to policy, cementing his reputation as a global leader in schizophrenia care.

Works

Search Professor Dan Siskind’s works on UQ eSpace

484 works between 2007 and 2027

201 - 220 of 484 works

2022

Conference Publication

Differentiation of unipolar and bipolar depression based on clinical features: a systematic review and meta-analysis.

Hopkins, Kristen, Siskind, Dan, McMahon, Laura, Philips, Elise, Lind, Penelope, Medland, Sarah and Warren, Nicola (2022). Differentiation of unipolar and bipolar depression based on clinical features: a systematic review and meta-analysis.. The 24th Annual Conference of the International Society for Bipolar Disorders, Online, 10–12 June 2022. Hoboken, NJ United States: Wiley-Blackwell.

Differentiation of unipolar and bipolar depression based on clinical features: a systematic review and meta-analysis.

2022

Journal Article

Increase in telemental health services on the Medicare Benefits Schedule after the start of the coronavirus pandemic: data from 2019 to 2021

Snoswell, Centaine L., Arnautovska, Urska, Haydon, Helen M., Siskind, Dan and Smith, Anthony C. (2022). Increase in telemental health services on the Medicare Benefits Schedule after the start of the coronavirus pandemic: data from 2019 to 2021. Australian Health Review, 46 (5), 544-549. doi: 10.1071/ah22078

Increase in telemental health services on the Medicare Benefits Schedule after the start of the coronavirus pandemic: data from 2019 to 2021

2022

Journal Article

Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors

Andric, Teodora, Winckel, Karl, Tanzer, Timothy David, Hollingworth, Samantha, Smith, Lesley, Isoardi, Katherine, Tan, Olivier and Siskind, Dan (2022). Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors. Therapeutic Advances in Psychopharmacology, 12 20451253221104947, 204512532211049. doi: 10.1177/20451253221104947

Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors

2022

Journal Article

After the acute crisis – engaging people with psychosis in rehabilitation-oriented care

Siskind, Dan and Yung, Alison (2022). After the acute crisis – engaging people with psychosis in rehabilitation-oriented care. World Psychiatry, 21 (2), 246-247. doi: 10.1002/wps.20970

After the acute crisis – engaging people with psychosis in rehabilitation-oriented care

2022

Conference Publication

Mental health diagnoses, frailty, and outcomes in a large cohort of Australian inpatients

Baral, S., Reid, N., Siskind, D., Warren, N., Gordon, E. and Hubbard, R. (2022). Mental health diagnoses, frailty, and outcomes in a large cohort of Australian inpatients. The Australian and New Zealand Society for Geriatric Medicine Annual Scientific Meeting 2022, Perth, WA Australia, 8 - 10 June 2022. Richmond, VIC Australia: John Wiley & Sons.

Mental health diagnoses, frailty, and outcomes in a large cohort of Australian inpatients

2022

Journal Article

Treatment strategies for clozapine-induced hypotension: a systematic review

Tanzer, Timothy David, Brouard, Thomas, Dal Pra, Samuel, Warren, Nicola, Barras, Michael, Kisely, Steve, Brooks, Emily and Siskind, Dan (2022). Treatment strategies for clozapine-induced hypotension: a systematic review. Therapeutic Advances in Psychopharmacology, 12 20451253221092931, 1-16. doi: 10.1177/20451253221092931

Treatment strategies for clozapine-induced hypotension: a systematic review

2022

Conference Publication

Mental Telehealth Services on the Medicare Benefits Scheme 2019 to 2021

Snoswell, Centaine L., Arnautovska, Urska, Haydon, Helen M., Siskind, Dan and Smith, Anthony C. (2022). Mental Telehealth Services on the Medicare Benefits Scheme 2019 to 2021. University of Queensland Early Career Researcher Symposium 2022, Brisbane, QLD Australia, 18-19 May 2022. The University of Queensland.

Mental Telehealth Services on the Medicare Benefits Scheme 2019 to 2021

2022

Journal Article

Clozapine—balancing the body and the mind

Siskind, Dan, Myles, Nick and Kisely, Steve (2022). Clozapine—balancing the body and the mind. The Lancet Psychiatry, 9 (5), 338-339. doi: 10.1016/S2215-0366(22)00078-5

Clozapine—balancing the body and the mind

2022

Conference Publication

TREATMENT STRATEGIES FOR CLOZAPINE-INDUCED SIALORRHEA: A SYSTEMATIC REVIEW AND META-ANALYSIS

Ravindran, G., Chen, S. Y., Zhang, Q., Kisely, S. and Siskind, D. (2022). TREATMENT STRATEGIES FOR CLOZAPINE-INDUCED SIALORRHEA: A SYSTEMATIC REVIEW AND META-ANALYSIS. LONDON: SAGE PUBLICATIONS LTD.

TREATMENT STRATEGIES FOR CLOZAPINE-INDUCED SIALORRHEA: A SYSTEMATIC REVIEW AND META-ANALYSIS

2022

Journal Article

Risk factors for Clozapine‐induced myocarditis and cardiomyopathy: a systematic review and meta‐analysis

Vickers, Mark, Ramineni, Vinay, Malacova, Eva, Eriksson, Lars, McMahon, Kirsten, Moudgil, Vikas, Scott, James and Siskind, Dan (2022). Risk factors for Clozapine‐induced myocarditis and cardiomyopathy: a systematic review and meta‐analysis. Acta Psychiatrica Scandinavica, 145 (5), 442-455. doi: 10.1111/acps.13398

Risk factors for Clozapine‐induced myocarditis and cardiomyopathy: a systematic review and meta‐analysis

2022

Journal Article

Assessing dietary, exercise, and non-pharmacological modalities within psychiatric hospitals

Metri, Najwa-Joelle, Ee, Carolyn, Wardle, Jon, Ng, Chee H., Siskind, Dan, Brakoulias, Vlasios, Ho, Fiona Yan-Yee, Wong, Vincent Wing-Hei, Naidoo, Uma, Eaton, Melissa, Firth, Joseph and Sarris, Jerome (2022). Assessing dietary, exercise, and non-pharmacological modalities within psychiatric hospitals. General Hospital Psychiatry, 76, 31-35. doi: 10.1016/j.genhosppsych.2022.03.006

Assessing dietary, exercise, and non-pharmacological modalities within psychiatric hospitals

2022

Journal Article

Reviving academic psychiatry in Australia and New Zealand

Suetani, Shuichi, Every-Palmer, Susanna, Galbally, Megan, Berk, Michael, Gill, Neeraj and Siskind, Dan (2022). Reviving academic psychiatry in Australia and New Zealand. Australian and New Zealand Journal of Psychiatry, 56 (5) 00048674221091927, 425-427. doi: 10.1177/00048674221091927

Reviving academic psychiatry in Australia and New Zealand

2022

Journal Article

Anti-glutamic acid decarboxylase antibody screening in first-episode psychosis

Warren, Nicola, Freier, Karen, Siskind, Dan, O’Gorman, Cullen, Blum, Stefan, Gillis, David and Scott, James G (2022). Anti-glutamic acid decarboxylase antibody screening in first-episode psychosis. Australian and New Zealand Journal of Psychiatry, 57 (4) 00048674221089560, 48674221089560-612. doi: 10.1177/00048674221089560

Anti-glutamic acid decarboxylase antibody screening in first-episode psychosis

2022

Journal Article

Outcomes of a co-located approach for metabolic health care for people with schizophrenia

Siskind, Dan, Yen, Wesley, Thuzar, Moe, Russell, Anthony, Warren, Nicola, Kisely, Steve, Kar Ray, Manaan and Motamarri, Balaji (2022). Outcomes of a co-located approach for metabolic health care for people with schizophrenia. Australasian Psychiatry, 30 (4), 103985622210807-522. doi: 10.1177/10398562221080742

Outcomes of a co-located approach for metabolic health care for people with schizophrenia

2022

Journal Article

A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders

Kisely, Steve, Connor, Mark, Somogyi, Andrew A. and Siskind, Dan (2022). A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders. Australian and New Zealand Journal of Psychiatry, 57 (3) 00048674221083868, 48674221083868-378. doi: 10.1177/00048674221083868

A systematic literature review and meta-analysis of the effect of psilocybin and methylenedioxymethamphetamine on mental, behavioural or developmental disorders

2022

Journal Article

Clozapine use and prevalence in Australia 2016–2020

Hollingworth, Samantha A, Oliver, Adrian, Winckel, Karl and Siskind, Dan (2022). Clozapine use and prevalence in Australia 2016–2020. Australian and New Zealand Journal of Psychiatry, 56 (3), 305-306. doi: 10.1177/00048674211025693

Clozapine use and prevalence in Australia 2016–2020

2022

Journal Article

Does the gut microbiome mediate antipsychotic-induced metabolic side effects in schizophrenia?

Vasileva, Svetlina S., Tucker, Jack, Siskind, Dan and Eyles, Darryl (2022). Does the gut microbiome mediate antipsychotic-induced metabolic side effects in schizophrenia?. Expert Opinion on Drug Safety, 21 (5), 1-15. doi: 10.1080/14740338.2022.2042251

Does the gut microbiome mediate antipsychotic-induced metabolic side effects in schizophrenia?

2022

Journal Article

Treatment strategies for clozapine induced nocturnal enuresis and urinary incontinence: a systematic review

Tanzer, Timothy, Warren, Nicola, McMahon, Laura, Barras, Michael, Kisely, Steve, Brooks, Emily, Wong, Emily and Siskind, Dan (2022). Treatment strategies for clozapine induced nocturnal enuresis and urinary incontinence: a systematic review. CNS Spectrums, 28 (2) PII S1092852922000050, 1-12. doi: 10.1017/s1092852922000050

Treatment strategies for clozapine induced nocturnal enuresis and urinary incontinence: a systematic review

2022

Journal Article

Correction: An international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, CRP, and clozapine Levels

de Leon, Jose, Schoretsanitis, Georgios, Smith, Robert L., Molden, Espen, Solismaa, Anssi, Seppälä, Niko, Kopeček, Miloslav, Švancer, Patrik, Olmos, Ismael, Ricciardi, Carina, Iglesias-Garcia, Celso, Iglesias-Alonso, Ana, Spina, Edoardo, Ruan, Can-Jun, Wang, Chuan-Yue, Wang, Gang, Tang, Yi-Lang, Lin, Shih-Ku, Lane, Hsien-Yuan, Kim, Yong Sik, Kim, Se Hyun, Rajkumar, Anto P., González-Esquivel, Dinora F., Jung-Cook, Helgi, Baptista, Trino, Rohde, Christopher, Nielsen, Jimmi, Verdoux, Hélène, Quiles, Clelia ... Müller, Daniel J. (2022). Correction: An international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, CRP, and clozapine Levels. Pharmacopsychiatry, 55 (2), e1-e1. doi: 10.1055/a-1737-1527

Correction: An international adult guideline for making clozapine titration safer by using six ancestry-based personalized dosing titrations, CRP, and clozapine Levels

2022

Journal Article

Frailty and severe mental illness: A systematic review and narrative synthesis

Pearson, Ella, Siskind, Dan, Hubbard, Ruth E., Gordon, Emily H., Coulson, Elizabeth and Warren, Nicola (2022). Frailty and severe mental illness: A systematic review and narrative synthesis. Journal of Psychiatric Research, 147, 166-175. doi: 10.1016/j.jpsychires.2022.01.014

Frailty and severe mental illness: A systematic review and narrative synthesis

Funding

Current funding

  • 2027 - 2031
    Transforming physical and mental health care for people living with schizophrenia
    NHMRC Investigator Grants
    Open grant
  • 2026 - 2027
    EVA-DHI: Economic Evaluation Framework for Digital Health Interventions: Stakeholder-Infor med Development and Pilot-Testing
    Queensland Bavaria Collaborative Research Program - Seed Grant
    Open grant
  • 2026
    Sedentary Time Elimination with Periodic activity Snacks (STEPS) study: codesign and evaluation of activity snacks in people with severe mental illness
    Metro South Hospital and Health Service
    Open grant
  • 2025 - 2028
    Randomised controlled trial of screening patients with Schizophrenia for obstructive sleep apnoea using in-laboratory polysomnography or 3-nights of home oximetry (MRFF OSDMOSA led by Macquarie Uni)
    Macquarie University
    Open grant
  • 2025 - 2030
    SYNDICAT: Synergy for the Development of Innovative Clinical Treatments in Schizophrenia (NHMRC 2024 Synergy Grant administered by Deakin University)
    Deakin University
    Open grant
  • 2024 - 2028
    A hybrid-II implementation-effectiveness trial of a peer-supported self-management tool for young people in preparation for early intervention in psychosis service discharge (MY PREP-ED) (Ex USYD)
    Medical Research Futures Fund
    Open grant
  • 2023 - 2028
    Self-care of Multimorbidity in schizophrenia supported by Peer workers: a Co-designed health Information Technology (SiMPlicITy) (externally led NHMRC 2022 Targeted Call administered via Uni of Syd)
    University of Sydney
    Open grant
  • 2023 - 2027
    Using risk profiles to overcome challenges in incorporating polygenic risk scores into clinical mental health practice (QIMR administered MRFF Genomics Health Future Mission grant)
    Queensland Institute of Medical Research
    Open grant
  • 2022 - 2029
    Schizophrenia and Weight Improvement From Tirzepatide (SWIFT)
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2021 - 2027
    Mental Health Australia General Clinical Trial Network (MAGNET) (MRFF Million Minds Mental Health Research Grant Led by Deakin University)
    Deakin University
    Open grant

Past funding

  • 2023 - 2024
    Cannabidiol (CBD) for Clozapine Refractory Schizophrenia (CanCloz)
    University of Sydney
    Open grant
  • 2022 - 2024
    A 40-year life course study of the effects of child maltreatment using linked birth cohort and administrative health data
    Metro South Health Research Support Scheme Project Grant
    Open grant
  • 2021 - 2025
    Reducing the mortality gap for people with schizophrenia
    NHMRC Investigator Grants
    Open grant
  • 2020 - 2026
    Helping people with schizophrenia living longer, healthier lives
    Queensland Advancing Clinical Research Fellowship
    Open grant
  • 2019 - 2025
    What is the impact of the National Bowel Cancer Screening Program on colorectal cancer outcomes for people over the age of 50 with severe mental illness?
    Cancer Council Australia
    Open grant
  • 2019 - 2021
    Identifying and treating patients with psychosis who are positive to anti-neuronal antibodies
    NHMRC Project Grant
    Open grant
  • 2019 - 2022
    Identifying and treating patients with psychosis who are positive to anti-neuronal antibodies (NHMRC Project Grant led by QIMR)
    Queensland Institute of Medical Research
    Open grant
  • 2018 - 2020
    The efficacy of adjunctive metformin to attenuate weight gain and visceral adiposity, and prevent conversion to diabetes in people with schizophrenia newly commenced on clozapine
    Society for Mental Health Research Inc
    Open grant
  • 2018 - 2019
    The efficacy of adjunctive metformin to attenuate weight gain and visceral adiposity, and prevent conversion to diabetes in people with schizophrenia newly commenced on clozapine
    The Australian Diabetes Society
    Open grant
  • 2017 - 2018
    Avant Doctors in Training Research Scholarship Program 2017
    Avant Mutual Group Limited
    Open grant
  • 2017 - 2019
    A comparison study of three physical activity measurement tools examining acceptability in people with psychotic disorders
    Society for Mental Health Research Inc
    Open grant
  • 2017 - 2019
    Acceptability of physical activity measures in people with psychotic disorders
    Royal Australian & New Zealand College Psychiatrists
    Open grant
  • 2016 - 2019
    Cardiometabolic Health of People with Severe and Persistent Mental Illness
    NHMRC Early Career Fellowships
    Open grant
  • 2016 - 2019
    N-Acetyl Cysteine In Schizophrenia Resistant to Clozapine: A Double-Blind Randomised Placebo-Controlled Trial Targeting Negative Symptoms (NHMRC Project grant administed by Uni Melbourne)
    University of Melbourne
    Open grant
  • 2015 - 2017
    Vaporising smoking-related harms in people with severe and persistent mental illness: A study of the acceptability of vaporised nicotine products for smoking cessation or long-term substitution
    Monash University
    Open grant
  • 2015 - 2017
    Quantifying the burden of perinatal depression in Australia and New Zealand
    RANZCP Pat, Toni and Peter Kinsman Research Scholarship
    Open grant
  • 2013 - 2016
    A MAP to better care: Applying the principles of advanced directives and motivational interviewing to discharge planning for psychiatric patients
    Australian Centre for Health Services Innovation
    Open grant

Supervision

Availability

Professor Dan Siskind is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Professor Dan Siskind directly for media enquiries about:

  • Cardiometabolic co-morbidity of schizophrenia
  • Treatment Refractory Schizophrenia

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