Overview
Background
Prof Siskind trained as a psychiatrist in Australia and the United States. He graduated from medicine at the University of Queensland in 1998. After working with Doctors Without Borders in Chechnya in 2000, he became interested in psychiatry. He moved to Boston in 2002, where he did his psychiatry residency at Boston University and a Master of Public Health at Harvard University. He returned to Brisbane in June 2008 as a clinical academic psychiatrist at the Metro South Addiction and Mental Health Service. He completed his Ph.D in Feb 2014. His research interests include clozapine and treatment refractory schizophrenia, the physical health of people with severe and persistent mental illness, supported accommodation, assertive community treatment and mental health services research. He was awarded an NHMRC Investigator Grant as a Leadership Fellow (L1 2027-2031) an Emerging Leadership Fellow (EL2 2021-2025) and an NHMRC Early Career Fellowship (ECF 2016-2019). He has a current CIA MRFF RCRDUN grant looking at treatments to reduce cardiometabolic morbidity among people with schizophrenia. He was the SIRS 2026 Outstanding Clinical and Community Research Award recipient, and was elected to the Australian Academy of Health and Medical Sciences in 2025. He has over 350 peer reviewed publications, including first author in the highly ranked Lancet, World Psychiatry, Lancet Psychiatry, BJPsych, ANZJP, & Schizophrenia Bulletin. He is a named investigator on over $65 million in competitive research grants, with over $9 million as CIA.
Availability
- Professor Dan Siskind is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Schizophrenia
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Physical Health Comorbidity
Research impacts
Prof Siskind's research has had direct, measurable impact on clinical practice and policy. His landmark studies on clozapine-associated neutropenia demonstrated that routine monitoring could safely cease after two years, evidence that has driven the removal of long-term monitoring mandates by regulators — improving safe and quality access to clozapine for more than 2.5 million people globally. His work establishing optimal plasma clozapine reference ranges is now used by pathology providers across Australia, while his findings on antipsychotic-associated metabolic risk and weight gain have been incorporated into international guidelines and adopted into clinical practice, with metformin augmentation now regularly prescribed for patients commencing antipsychotics. His Lancet Psychiatry Commission on physical health in people with mental illness helped set the global agenda for integrating physical and mental healthcare, informing policy from the WHO, OECD, and across multiple countries. As Chair of the INTEGRATE Steering Committee, he led development of the first consensus-based, algorithmic international guidelines for schizophrenia treatment, which have been endorsed by peak bodies. Through sustained engagement with regulators, professional colleges and health services, Prof Siskind has ensured his research translates rapidly from bench to bedside to policy, cementing his reputation as a global leader in schizophrenia care.
Works
Search Professor Dan Siskind’s works on UQ eSpace
2018
Journal Article
Improvement of cognitive function in schizophrenia with N-acetylcysteine: A theoretical review
Yolland, Caitlin O. B., Phillipou, Andrea, Castle, David J., Neill, Erica, Hughes, Matthew E., Galletly, Cherrie, Smith, Zoe M., Francis, Paul S., Dean, Olivia M., Sarris, Jerome, Siskind, Dan, Harris, Anthony W. F. and Rossell, Susan L. (2018). Improvement of cognitive function in schizophrenia with N-acetylcysteine: A theoretical review. Nutritional Neuroscience, 23 (2), 1-10. doi: 10.1080/1028415X.2018.1478766
2018
Journal Article
Meta-analysis examining the epidemiology of clozapine-associated neutropenia
Myles, N., Myles, H., Xia, S., Large, M., Kisely, S., Galletly, C., Bird, R. and Siskind, D. (2018). Meta-analysis examining the epidemiology of clozapine-associated neutropenia. Acta Psychiatrica Scandinavica, 138 (2), 101-109. doi: 10.1111/acps.12898
2018
Journal Article
Augmentation strategies for clozapine refractory schizophrenia: a systematic review and meta-analysis
Siskind, Dan J., Lee, Michael, Ravindran, Arul, Zhang, Qichen, Ma, Evelyn, Motamarri, Balaji and Kisely, Steve (2018). Augmentation strategies for clozapine refractory schizophrenia: a systematic review and meta-analysis. Australian & New Zealand Journal of Psychiatry, 52 (8), 4867418772351-767. doi: 10.1177/0004867418772351
2018
Journal Article
A systematic review and meta-analysis of deep brain stimulation for depression
Kisely, Steve, Li, Amy, Warren, Nicola and Siskind, Dan (2018). A systematic review and meta-analysis of deep brain stimulation for depression. Depression and Anxiety, 35 (5), 468-480. doi: 10.1002/da.22746
2018
Journal Article
The language we use - the effect of writing mental health care plans in the first person
Wyder, Marianne, Kisely, Steve, Meurk, Carla, Dietrich, Josie, Fawcett, Teresa, Siskind, Dan, Robinson, Gail and Crompton, David (2018). The language we use - the effect of writing mental health care plans in the first person. Australasian Psychiatry, 26 (5), 103985621877225-502. doi: 10.1177/1039856218772251
2018
Journal Article
High rates of respiratory symptoms and airway disease in mental health inpatients in a tertiary centre
Burke, Andrew J., Hay, Karen, Chadwick, Alex, Siskind, Dan and Sheridan, Judith (2018). High rates of respiratory symptoms and airway disease in mental health inpatients in a tertiary centre. Internal Medicine Journal, 48 (4), 433-438. doi: 10.1111/imj.13594
2018
Conference Publication
41.1 What do meta-analyses tell us about clozapine’s efficacy and effectiveness for treatment refractory schizophrenia?
Siskind, Dan, Kisely, Steve, Land, Rachel and McCartney, Lara (2018). 41.1 What do meta-analyses tell us about clozapine’s efficacy and effectiveness for treatment refractory schizophrenia?. Sixth Biennial SIRS Conference, Florence, Italy, 4-8 April 2018. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/schbul/sby014.169
2018
Journal Article
Clozapine-related neutropenia, myocarditis and cardiomyopathy adverse event reports in Australia 1993-2014
Hollingworth, Samantha A., Winckel, Karl, Saiepour, Nargess, Wheeler, Amanda J., Myles, Nicholas and Siskind, Dan (2018). Clozapine-related neutropenia, myocarditis and cardiomyopathy adverse event reports in Australia 1993-2014. Psychopharmacology, 235 (7), 1915-1921. doi: 10.1007/s00213-018-4881-0
2018
Journal Article
Disentangling schizophrenia spectrum disorders
Suetani, S., Siskind, D., Scott, J. G. and McGrath, J. J. (2018). Disentangling schizophrenia spectrum disorders. Acta Psychiatrica Scandinavica, 137 (4), 365-366. doi: 10.1111/acps.12865
2018
Journal Article
CoMET: a protocol for a randomised controlled trial of co-commencement of METformin as an adjunctive treatment to attenuate weight gain and metabolic syndrome in patients with schizophrenia newly commenced on clozapine
Siskind, Dan, Friend, Nadia, Russell, Anthony, McGrath, John J., Lim, Carmen, Patterson, Sue, Flaws, Dylan, Stedman, Terry, Moudgil, Vikas, Sardinha, Savio, Suetani, Shuichi, Kisely, Steve, Winckel, Karl and Baker, Andrea (2018). CoMET: a protocol for a randomised controlled trial of co-commencement of METformin as an adjunctive treatment to attenuate weight gain and metabolic syndrome in patients with schizophrenia newly commenced on clozapine. BMJ Open, 8 (3) e021000, e021000. doi: 10.1136/bmjopen-2017-021000
2018
Journal Article
Identifying characteristics and practices of multidisciplinary team reviews for patients with severe mental illness: a systematic review
Woody, Charlotte A., Baxter, Amanda J., Harris, Meredith G., Siskind, Dan J. and Whiteford, Harvey A. (2018). Identifying characteristics and practices of multidisciplinary team reviews for patients with severe mental illness: a systematic review. Australasian Psychiatry, 26 (3), 1039856217751783-275. doi: 10.1177/1039856217751783
2018
Journal Article
Metformin prescription in psychiatry
Suetani, Shuichi, Parker, Stephen, Korman, Nicole, Crompton, David, Dark, Frances and Siskind, Dan (2018). Metformin prescription in psychiatry. Australasian Psychiatry, 26 (1), 107-107. doi: 10.1177/1039856217726688
2018
Conference Publication
Building partnerships in academic psychiatry: a guide for new investigators and the scholarly project
Clark, S., Kisely, S., Parker, S., Harris, A., Suetani, S. and Siskind, D. (2018). Building partnerships in academic psychiatry: a guide for new investigators and the scholarly project. RANZCP 2018 Congress, Auckland Convention Centre, 13-17 May 2018. London, United Kingdom: Sage Publications.
2018
Conference Publication
Treatment of clozapine-associated obesity and diabetes with exenatide (Codex) in adults with schizophrenia: a randomised controlled trial
Siskind, Dan, Russell, Anthony, Gamble, Clare, Winckel, Karl, Hollingworth, Sam and Kisely, Steve (2018). Treatment of clozapine-associated obesity and diabetes with exenatide (Codex) in adults with schizophrenia: a randomised controlled trial. 6th Biennial Conference of the Schizophrenia International Research Society (SIRS), Florence, Italy, 4-8 April 2018. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/schbul/sby016.436
2018
Conference Publication
Barriers and Enablers to Primary Care for Patients with Severe and Persistent Mental Illness
WIlliams, Ryan , Sturman, Nancy , Wyder, Marianne and Siskind, Dan (2018). Barriers and Enablers to Primary Care for Patients with Severe and Persistent Mental Illness. 60th Clinical Update, RACGP QLD, Brisbane QLD Australia, May 2018.
2018
Conference Publication
Is deep brain stimulation a pacemaker for the brain? A systematic review and meta-analysis of its efficacy in depression
Kisely, S., Li, A., Warren, N. and Siskind, D. (2018). Is deep brain stimulation a pacemaker for the brain? A systematic review and meta-analysis of its efficacy in depression. RANZCP 2018 Congress, Auckland Convention Centre, 13-17 May 2018. London, United Kingdom: Sage Publications.
2018
Conference Publication
Tips for consultants when supervising research projects with registrars and medical students
Siskind, D., Kisely, S., Parker, S. and Suetani, S. (2018). Tips for consultants when supervising research projects with registrars and medical students. RANZCP 2018 Congress, Auckland Convention Centre, 13-17 May 2018. London, United Kingdom: Sage Publications.
2018
Conference Publication
Barriers and enablers to primary care for patients with severe and persistent mental illness
Williams, R., Siskind, D., Wyder, M. and Sturman, N. (2018). Barriers and enablers to primary care for patients with severe and persistent mental illness. GP18, Gold Coast, QLD, Australia, 11-13 October 2018.
2018
Journal Article
Adverse cardiac events in out-patients initiating clozapine treatment: a nationwide register-based study
Rohde, C., Polcwiartek, C., Kragholm, K., Ebdrup, B. H., Siskind, D. and Nielsen, J. (2018). Adverse cardiac events in out-patients initiating clozapine treatment: a nationwide register-based study. Acta Psychiatrica Scandinavica, 137 (1), 47-53. doi: 10.1111/acps.12827
2018
Conference Publication
Making supervision work: practical recommendations for supervisees
Parker, S., Suetani, S., Motamarri, B. and Siskind, D. (2018). Making supervision work: practical recommendations for supervisees. RANZCP 2018 Congress, Auckland Convention Centre, 13-17 May 2018. London, United Kingdom: Sage Publications.
Funding
Current funding
Supervision
Availability
- Professor Dan Siskind is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Food and nutrition security in individuals with severe mental illness
Principal Advisor
Other advisors: Dr Urska Arnautovska
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Doctor Philosophy
Manifestations, impacts, and clinical implications of physical multimorbidity in people living with severe mental illness
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Steve Kisely
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Master Philosophy
A quantitative and qualitative study of forensic orders in Queensland
Associate Advisor
Other advisors: Professor Steve Kisely, Dr Claudia Bull, Dr Mike Trott
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Doctor Philosophy
Smoking Cessation in People with a Serious Mental Illness
Associate Advisor
Other advisors: Professor Steve Kisely, Professor Coral Gartner
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Doctor Philosophy
Measuring cognitive flexibility in rodents
Associate Advisor
Other advisors: Professor Thomas Burne
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Doctor Philosophy
Management of myocarditis among people with schizophrenia commencing clozapine
Associate Advisor
Other advisors: Associate Professor Nicola Warren
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Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Associate Advisor
Other advisors: Honorary Professor Sarah Medland
Completed supervision
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2026
Doctor Philosophy
The Quality and Safe Use of Clozapine
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Michael Barras, Professor Steve Kisely
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2025
Doctor Philosophy
Investigating clozapine rechallenge using granulocyte-colony stimulating factor in people previously experiencing clozapine-associated neutropenia.
Principal Advisor
Other advisors: Professor Steve Kisely
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2021
Doctor Philosophy
Psychiatric clinical decision making in anti-NMDA receptor encephalitis
Principal Advisor
Other advisors: Associate Professor Stefan Blum, Professor Steve Kisely
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2024
Doctor Philosophy
The Role of the Gut Microbiome in Psychiatric Illness: From Prenatal Risk Factors to Treatment Resistance
Associate Advisor
Other advisors: Honorary Professor Jake Gratten, Honorary Professor Darryl Eyles
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2023
Doctor Philosophy
Measuring and improving cognition in a rodent model relevant to schizophrenia
Associate Advisor
Other advisors: Dr James Kesby, Professor Thomas Burne
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2022
Doctor Philosophy
Nose-to-Brain Delivery of Clozapine in Sol-Gel Systems
Associate Advisor
Other advisors: Associate Professor Harendra Parekh, Dr Preeti Pandey, Dr James Robert Falconer
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2020
Doctor Philosophy
Exploring the characteristics and service needs of carers for adults with mental illness to inform mental health service planning
Associate Advisor
Other advisors: Associate Professor Meredith Harris
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2020
Doctor Philosophy
Who receives what, from whom, and to what effect at clinically operated, community-based residential mental health rehabilitation for Severe and Persistent Mental Illness in Australia?
Associate Advisor
Other advisors: Associate Professor Meredith Harris
Media
Enquiries
Contact Professor Dan Siskind directly for media enquiries about:
- Cardiometabolic co-morbidity of schizophrenia
- Treatment Refractory Schizophrenia
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