
Overview
Background
Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.
Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.
Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.
Availability
- Professor Peter Visscher is:
- Not available for supervision
Fields of research
Qualifications
- Masters (Coursework) of Science, University of Edinburgh
- Doctor of Philosophy, University of Edinburgh
Research impacts
Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.
Works
Search Professor Peter Visscher’s works on UQ eSpace
2016
Journal Article
Concepts and misconceptions about the polygenic additive model applied to disease
Visscher, Peter M. and Wray, Naomi R. (2016). Concepts and misconceptions about the polygenic additive model applied to disease. Human Heredity, 80 (4), 165-170. doi: 10.1159/000446931
2016
Journal Article
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
van Rheenen, Wouter, Shatunov, Aleksey, Dekker, Annelot M., McLaughlin, Russell L., Diekstra, Frank P., Pulit, Sara L., van der Spek, Rick A. A., Vosa, Urmo, de Jong, Simone, Robinson, Matthew R., Yang, Jian, Fogh, Isabella, van Doormaal, Perry T. C., Tazelaar, Gijs H. P., Koppers, Max, Blokhuis, Anna M., Sproviero, William, Jones, Ashley R., Kenna, Kevin P., van Eijk, Kristel R., Harschnitz, Oliver, Schellevis, Raymond D., Brands, William J., Medic, Jelena, Menelaou, Androniki, Vajda, Alice, Ticozzi, Nicola, Lin, Kuang, Rogelj, Boris ... Veldink, Jan H. (2016). Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis. Nature Genetics, 48 (9) 611, 1043-1048. doi: 10.1038/ng.3622
2016
Journal Article
Across-cohort QC analyses of GWAS summary statistics from complex traits
Chen, Guo-Bo, Lee, Sang Hong, Robinson, Matthew R., Trzaskowski, Maciej, Zhu, Zhi-Xiang, Winkler, Thomas W., Day, Felix R., Croteau-Chonka, Damien C., Wood, Andrew R., Locke, Adam E., Kutalik, Zoltán, Loos, Ruth J. F., Frayling, Timothy M., Hirschhorn, Joel N., Yang, Jian, Wray, Naomi R. and Visscher, Peter M. (2016). Across-cohort QC analyses of GWAS summary statistics from complex traits. European Journal of Human Genetics, 25 (1), 137-146. doi: 10.1038/ejhg.2016.106
2016
Journal Article
Microbial and diagenetic steps leading to the mineralisation of Great Salt Lake microbialites
Pace, Aurelie, Bourillot, Raphael, Bouton, Anthony, Vennin, Emmanuelle, Galaup, Serge, Bundeleva, Irina, Patrier, Patricia, Dupraz, Christophe, Thomazo, Christophe, Sansjofre, Pierre, Yokoyama, Yusuke, Franceschi, Michel, Anguy, Yannick, Pigot, Lea, Virgone, Aurelien and Visscher, Pieter T. (2016). Microbial and diagenetic steps leading to the mineralisation of Great Salt Lake microbialites. Scientific Reports, 6 31495. doi: 10.1038/srep31495
2016
Journal Article
GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs
Yang, Jian, Lee, S. Hong, Wray, Naomi R., Goddard, Michael E. and Visscher, Peter M. (2016). GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs. Proceedings of the National Academy of Sciences, 113 (32), E4579-E4580. doi: 10.1073/pnas.1602743113
2016
Journal Article
Enhanced development of lacustrine microbialites on gravity flow deposits, Great Salt Lake, Utah, USA
Bouton, Anthony, Vennin, Emmanuelle, Mulder, Thierry, Pace, Aurelie, Bourillot, Raphael, Thomazo, Christophe, Brayard, Arnaud, Goslar, Tomasz, Buoncristiani, Jean-Francois, Desaubliaux, Guy and Visscher, Pieter T. (2016). Enhanced development of lacustrine microbialites on gravity flow deposits, Great Salt Lake, Utah, USA. Sedimentary Geology, 341, 1-12. doi: 10.1016/j.sedgeo.2016.05.004
2016
Journal Article
A plethora of pleiotropy across complex traits
Visscher, Peter M. and Yang, Jian (2016). A plethora of pleiotropy across complex traits. Nature Genetics, 48 (7), 707-708. doi: 10.1038/ng.3604
2016
Journal Article
Genetic pleiotropy in complex traits and diseases: implications for genomic medicine
Gratten, Jacob and Visscher, Peter M. (2016). Genetic pleiotropy in complex traits and diseases: implications for genomic medicine. Genome Medicine, 8 (78) 78, 1-3. doi: 10.1186/s13073-016-0332-x
2016
Journal Article
A genome-wide association study identifies variants in <i>KCNIP4</i> associated with ACE inhibitor-induced cough
Mosley, J. D., Shaffer, C. M., Van Driest, S. L., Weeke, P. E., Wells, Q. S., Karnes, J. H., Edwards, D. R. Velez, Wei, W-Q, Teixeira, P. L., Bastarache, L., Crawford, D. C., Li, R., Manolio, T. A., Bottinger, E. P., McCarty, C. A., Linneman, J. G., Brilliant, M. H., Pacheco, J. A., Thompson, W., Chisholm, R. L., Jarvik, G. P., Crosslin, D. R., Carrell, D. S., Baldwin, E., Ralston, J., Larson, E. B., Grafton, J., Scrol, A., Jouni, H. ... Roden, D. M. (2016). A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough. Pharmacogenomics Journal, 16 (3), 231-237. doi: 10.1038/tpj.2015.51
2016
Journal Article
External controls on the distribution, fabrics and mineralization of modern microbial mats in a coastal hypersaline lagoon, Cayo Coco (Cuba)
Bouton, Anthony, Vennin, Emmanuelle, Pace, Aurelie, Bourillot, Raphael, Dupraz, Christophe, Thomazo, Christophe, Brayard, Arnaud, Desaubliaux, Guy and Visscher, Pieter T. (2016). External controls on the distribution, fabrics and mineralization of modern microbial mats in a coastal hypersaline lagoon, Cayo Coco (Cuba). Sedimentology, 63 (4), 972-1016. doi: 10.1111/sed.12246
2016
Journal Article
A stroke of insight from genetics
Visscher, Peter M. and Veldink, Jan H. (2016). A stroke of insight from genetics. Lancet Neurology, 15 (7), 653-654. doi: 10.1016/S1474-4422(16)30028-X
Featured
2016
Journal Article
Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations
Gratten, Jacob, Wray, Naomi R., Peyrot, Wouter J., McGrath, John J., Visscher, Peter M. and Goddard, Michael E. (2016). Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations. Nature Genetics, 48 (7), 718-+. doi: 10.1038/ng.3577
2016
Journal Article
Genome-wide association study identifies 74 loci associated with educational attainment
Okbay, Aysu, Beauchamp, Jonathan P., Fontana, Mark Alan, Lee, James J., Pers, Tune H., Rietveld, Cornelius A., Turley, Patrick, Chen, Guo-Bo, Emilsson, Valur, Meddens, S. Fleur W., Oskarsson, Sven, Pickrell, Joseph K., Thom, Kevin, Timshel, Pascal, de Vlaming, Ronald, Abdellaoui, Abdel, Ahluwalia, Tarunveer S., Bacelis, Jonas, Baumbach, Clemens, Bjornsdottir, Gyda, Brandsma, Johannes H., Concas, Maria Pina, Derringer, Jaime, Furlotte, Nicholas A., Galesloot, Tessel E., Girotto, Giorgia, Gupta, Richa, Hall, Leanne M., Harris, Sarah E. ... Benjamin, Daniel J. (2016). Genome-wide association study identifies 74 loci associated with educational attainment. Nature, 533 (7604), 539-542. doi: 10.1038/nature17671
2016
Journal Article
Evidence for genetic overlap between schizophrenia and age at first birth in women
Mehta, Divya, Tropf, Felix C., Gratten, Jacob, Bakshi, Andrew, Zhu, Zhihong, Bacanu, Silviu-Alin, Hemani, Gibran, Magnusson, Patrik K. E., Barban, Nicola, Esko, Tonu, Metspalu, Andres, Snieder, Harold, Mowry, Bryan J., Kendler, Kenneth S., Yang, Jian, Visscher, Peter M., McGrath, John J., Mills, Melinda C., Wray, Naomi R. and Lee, S. Hong (2016). Evidence for genetic overlap between schizophrenia and age at first birth in women. Jama Psychiatry, 73 (5), 497-505. doi: 10.1001/jamapsychiatry.2016.0129
2016
Journal Article
Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
Zhu, Zhihong, Zhang, Futao, Hu, Han, Bakshi, Andrew, Robinson, Matthew R., Powell, Joseph E., Montgomery,Grant W., Goddard, Michael E., Wray, Naomi R., Visscher, Peter M. and Yang, Jian (2016). Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets. Nature Genetics, 48 (5), 481-487. doi: 10.1038/ng.3538
2016
Journal Article
Corrigendum: The epigenetic clock and telomere length are independently associated with chronological age and mortality [Int J Epidemiol., 45, 2, (424-432)(2016)] DOI: 10.1093/ije/dyw041
Marioni, Riccardo E., Harris, Sarah E., Shah, Sonia, McRae, Allan F., von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R., Visscher, Peter M. and Deary, Ian J. (2016). Corrigendum: The epigenetic clock and telomere length are independently associated with chronological age and mortality [Int J Epidemiol., 45, 2, (424-432)(2016)] DOI: 10.1093/ije/dyw041. International Journal of Epidemiology, 47 (1) dyx217, 356-356. doi: 10.1093/ije/dyx233
2016
Journal Article
The epigenetic clock and telomere length are independently associated with chronological age and mortality
Marioni, Riccardo E., Harris, Sarah E., Shah, Sonia, McRae, Allan F., von Zglinicki, Thomas, Martin-Ruiz, Carmen, Wray, Naomi R., Visscher, Peter M. and Deary, Ian J. (2016). The epigenetic clock and telomere length are independently associated with chronological age and mortality. International Journal of Epidemiology, 45 (2), 424-432. doi: 10.1093/ije/dyw041
2016
Journal Article
Shared genetic control of expression and methylation in peripheral blood
Shakhbazov, Konstantin, Powell, Joseph E., Hemani, Gibran, Henders, Anjali K., Martin, Nicholas G., Visscher, Peter M., Montgomery, Grant W. and McRae, Allan F. (2016). Shared genetic control of expression and methylation in peripheral blood. BMC Genomics, 17 (1) 278, 278. doi: 10.1186/s12864-016-2498-4
2016
Journal Article
Authors' response to Kaufman and Muntaner
Arden, Rosalind, Luciano, Michelle, Deary, Ian J., Reynolds, Chandra A., Pedersen, Nancy L., Plassman, Brenda L., McGue, Matt, Christensen, Kaare and Visscher, Peter M. (2016). Authors' response to Kaufman and Muntaner. International Journal of Epidemiology, 45 (2) dyw020, 578-579. doi: 10.1093/ije/dyw020
2016
Journal Article
A Genome-Wide Association Study Provides New Evidence That <i>CACNA1C</i> Gene is Associated With Diabetic Cataract
Chang, Cheng, Zhang, Kaida, Veluchamy, Abirami, Hebert, Harry L., Looker, Helen C., Colhoun, Helen M., Palmer, Colin N. A. and Meng, Weihua (2016). A Genome-Wide Association Study Provides New Evidence That CACNA1C Gene is Associated With Diabetic Cataract. Investigative Ophthalmology & Visual Science, 57 (4), 2246-2250. doi: 10.1167/iovs.16-19332
Supervision
Availability
- Professor Peter Visscher is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Statistical methods and application to analyses genome and trait data from large biobanks
Principal Advisor
Other advisors: Dr Kathryn Kemper, Professor Loic Yengo
-
Doctor Philosophy
Genetic architecture and evolution of complex traits across populations in humans
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng
Completed supervision
-
2022
Doctor Philosophy
Using whole-genome sequence data to elucidate complex trait variation
Principal Advisor
-
2020
Doctor Philosophy
Genetic and genomic analyses on ageing and age-related complex traits
Principal Advisor
Other advisors: Dr Allan McRae
-
2010
Doctor Philosophy
Mitochondrial and autosomal genetic analyses in the Australian population
Principal Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Quantitative genetics approaches to elucidate the role of DNA methylation in complex trait variation
Associate Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Genomic signature of non-random mating in human complex traits
Associate Advisor
Other advisors: Professor Loic Yengo
-
2024
Doctor Philosophy
Insights into pleiotropic effects across the human genome for complex traits and diseases
Associate Advisor
Other advisors: Dr Allan McRae
-
2022
Doctor Philosophy
Genetic analyses of complex traits using biobank data
Associate Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Within and Across Populations Complex Traits and Diseases Prediction Using Summary Statistics from Large-scale Genome-wide Association Studies
Associate Advisor
Other advisors: Professor Loic Yengo
-
2020
Doctor Philosophy
Genetic Differentiation of Human Complex Traits across Worldwide Populations
Associate Advisor
-
2020
Doctor Philosophy
Improving fine-mapping methodology using DNA methylation as a model trait
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Allan McRae
-
2019
Doctor Philosophy
Sexual dimorphism in human gene expression
Associate Advisor
Other advisors: Dr Allan McRae
-
2019
Doctor Philosophy
Systems Genomics of Parkinson's Disease
Associate Advisor
Other advisors: Honorary Professor Jake Gratten
-
2017
Doctor Philosophy
The Genetic Architecture of Psychiatric Disorders
Associate Advisor
Other advisors: Professor Naomi Wray
-
2017
Doctor Philosophy
Characterization of the genetic and environmental factors driving gene expression variability
Associate Advisor
Media
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