
Overview
Background
Visscher joined the University of Queensland in 2011, where he is Professor of Quantitative Genetics. He is a Laureate Fellow of the Australian Research Council. Visscher was elected a Fellow of the Australian Academy of Science in 2010, a Fellow of the Royal Society (London) in 2018 and a Foreign Member of the Royal Netherlands Academy of Arts and Sciences in 2018.
Visscher’s research is about genetic variation for complex traits (including quantitative traits and disease) in populations, with the broad aim to understand and quantify the causes and consequences of human trait variation.
Prof Peter Visscher, Prof Naomi Wray and Prof Jian Yang together comprise the Executive Team of the Program in Complex Trait Genomics (PCTG). PCTG comprises a critical mass of more than 30 post-doctoral researchers plus research assistants and students, all supported by external grant funding. Their skills lie in the ability to develop and apply statistical methods within the framework of quantitative, population and statistical genetics and to use theory to understand and predict results from data analyses. They play leading roles in the international research consortia. The focus of current research activities is in the detection and fine-mapping of loci underlying complex traits (including common disease), based upon theoretical studies and applications of methods to large datasets, in population genetics studies using theoretical approaches and high-density genetic marker data, and in systems genomics studies.
Availability
- Professor Peter Visscher is:
- Not available for supervision
Fields of research
Qualifications
- Masters (Coursework) of Science, University of Edinburgh
- Doctor of Philosophy, University of Edinburgh
Research impacts
Visscher's research focuses on understanding individual differences betweeen people in traits that are important for health outcomes and ageing. A better understanding of the genes that underlie variation in risk to diseases may lead to better treatments.
Works
Search Professor Peter Visscher’s works on UQ eSpace
2016
Journal Article
The definitions of three-dimensional landmarks on the human face: an interdisciplinary view
Katina, Stanislav, McNeil, Kathryn, Ayoub, Ashraf, Guilfoyle, Brendan, Khambay, Balvinder, Siebert, Paul, Sukno, Federico, Rojas, Mario, Vittert, Liberty, Waddington, John, Whelan, Paul F. and Bowman, Adrian W. (2016). The definitions of three-dimensional landmarks on the human face: an interdisciplinary view. Journal of Anatomy, 228 (3), 355-365. doi: 10.1111/joa.12407
2016
Journal Article
Human complex trait genetics in the 21st century
Visscher, Peter M. (2016). Human complex trait genetics in the 21st century. Genetics, 202 (2), 377-379. doi: 10.1534/genetics.115.180513
2016
Journal Article
Leveraging genomic annotations and pleiotropic enrichment for improved replication rates in schizophrenia GWAS
Wang, Yunpeng, Thompson, Wesley K., Schork, Andrew J., Holland, Dominic, Chen, Chi-Hua, Bettella, Francesco, Desikan, Rahul S., Li, Wen, Witoelar, Aree, Zuber, Verena, Devor, Anna, Noethen, Markus M., Rietschel, Marcella, Chen, Qiang, Werge, Thomas, Cichon, Sven, Weinberger, Daniel R., Djurovic, Srdjan, O'Donovan, Michael, Visscher, Peter M., Andreassen, Ole A. and Dale, Anders M. (2016). Leveraging genomic annotations and pleiotropic enrichment for improved replication rates in schizophrenia GWAS. Plos Genetics, 12 (1) e1005803, e1005803. doi: 10.1371/journal.pgen.1005803
2016
Journal Article
DNA methylation-based measures of biological age: meta-analysis predicting time to death
Chen, Brian H., Marioni, Riccardo E., Colicino, Elena, Peters, Marjolein J., Ward-Caviness, Cavin K., Tsai, Pei-Chien, Roetker, Nicholas S., Just, Allan C., Demerath, Ellen W., Guan, Weihua, Bressler, Jan, Fornage, Myriam, Studenski, Stephanie, Vandiver, Amy R., Moore, Ann Zenobia, Tanaka, Toshiko, Kiel, Douglas P., Liang, Liming, Vokonas, Pantel, Schwartz, Joel, Lunetta, Kathryn L., Murabito, Joanne M., Bandinelli, Stefania, Hernandez, Dena G., Melzer, David, Nalls, Michael, Pilling, Luke C., Price, Timothy R., Singleton, Andrew B. ... Horvath, Steve (2016). DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging, 8 (9), 1844-1865. doi: 10.18632/aging.101020
2016
Journal Article
Genes influence the amplitude and timing of brain hemodynamic responses
Shan, Zuyao Y., Vinkhuyzen, Anna A. E., Thompson, Paul M., McMahon, Katie L., Blokland, Gabriella A.M., de Zubicaray, Greig I., Calhoun, Vince, Martin, Nicholas G., Visscher, Peter M., Wright, Margaret J. and Reutens, David C. (2016). Genes influence the amplitude and timing of brain hemodynamic responses. NeuroImage, 124 (Part A), 663-671. doi: 10.1016/j.neuroimage.2015.09.016
2016
Conference Publication
Multivariate Genetic Risk Scores Can Increase Risk Prediction Accuracy for a wide Range of Traits
Maier, Robert, Robinson, Matt, Wray, Naomi and Visscher, Peter (2016). Multivariate Genetic Risk Scores Can Increase Risk Prediction Accuracy for a wide Range of Traits. Annual Meeting of the International-Genetic-Epidemiology-Society, Toronto Canada, 24-26 October 2016. United States: John Wiley & Sons.
2015
Journal Article
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index
Yang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A. E., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, Study, Lifelines Cohort, Esko, Tonu, Milani, Lili, Maegi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K. E., Pedersen, Nancy L., Ingelsson, Erik and Visscher, Peter M. (2015). Genome-wide genetic homogeneity between sexes and populations for human height and body mass index. Human Molecular Genetics, 24 (25), 7445-7449. doi: 10.1093/hmg/ddv443
2015
Journal Article
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
Loh, Po-Ru, Bhatia, Gaurav, Gusev, Alexander, Finucane, Hilary K., Bulik-Sullivan, Brendan K., Pollack, Samuela J., de Candia, Teresa R., Lee, Sang Hong, Wray, Naomi R., Kendler, Kenneth S., O'Donovan, Michael C., Neale, Benjamin M., Patterson, Nick, Price, Alkes L., Schizophrenia Working Group of the Psychiatric Genomics Consortium, Visscher, Peter M. and Mowry, Bryan J. (2015). Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. Nature Genetics, 47 (12), 1385-1392. doi: 10.1038/ng.3431
2015
Conference Publication
Fifty years of twin studies on psychiatric traits
Polderman, Tinca, Benyamin, Beben, De Leeuw, Christiaan, Sullivan, Patrick, Bochoven, Arjen, Visscher, Peter and Posthuma, D. (2015). Fifty years of twin studies on psychiatric traits. 45th Annual Meeting of the Behavior-Genetics-Association, San Diego Ca, Jun 17-20, 2015. NEW YORK: SPRINGER.
2015
Conference Publication
50 years of twin studies: a meta-analysis of all human traits
Posthuma, D., Benyamin, Beben, De Leeuw, Christiaan, Bochoven, Arjen, Sullivan, Patrick, Visscher, Peter and Polderman, Tinca (2015). 50 years of twin studies: a meta-analysis of all human traits. 45th Annual Meeting of the Behavior-Genetics-Association, San Diego Ca, Jun 17-20, 2015. NEW YORK: SPRINGER.
2015
Journal Article
The transcriptional landscape of age in human peripheral blood
Peters, Marjolein J., Joehanes, Roby, Pilling, Luke C., Schurmann, Claudia, Conneely, Karen N., Powell, Joseph, Reinmaa, Eva, Sutphin, George L., Zhernakova, Alexandra, Schramm, Katharina, Wilson, Yana A., Kobes, Sayuko, Tukiainen, Taru, Ramos, Yolande F., Goring, Harald H. H., Fornage, Myriam, Liu, Yongmei, Gharib, Sina A., Stranger, Barbara E., De Jager, Philip L., Aviv, Abraham, Levy, Daniel, Murabito, Joanne M., Munson, Peter J., Huan, Tianxiao, Hofman, Albert, Uitterlinden, Andre G., Rivadeneira, Fernando, Van Rooij, Jeroen ... NABEC/UKBEC Consortium (2015). The transcriptional landscape of age in human peripheral blood. Nature Communications, 6 (1) 8570, 8570.1-8570.14. doi: 10.1038/ncomms9570
2015
Journal Article
The UK10K project identifies rare variants in health and disease
The UK10K Consortium, Evans, David M., Kemp, John P., Visscher, Peter M. and Yang, Jian (2015). The UK10K project identifies rare variants in health and disease. Nature, 526 (7571), 82-89. doi: 10.1038/nature14962
2015
Journal Article
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
Vilhjalmsson, Bjarni J., Yang, Jian, Finucane, Hilary K., Gusev, Alexander, Lindstrom, Sara, Ripke, Stephan, Genovese, Giulio, Loh, Po-Ru, Bhatia, Gaurav, Do, Ron, Hayeck, Tristan, Won, Hong-Hee, Kathiresan, Sekar, Pato, Michele, Pato, Carlos, Tamimi, Rulla, Stahl, Eli, Zaitlen, Noah, Pasaniuc, Bogdan, Belbin, Gillian, Kenny, Eimear E., Schierup, Mikkel H., De Jager, Philip, Patsopouos, Nikolaos A., Mc Carroll, Steve, Daly, Mark, Purce, Shaun, Chasman, Daniel, Neale, Benjamin ... Price, Alkes L. (2015). Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. American Journal of Human Genetics, 97 (4), 576-592. doi: 10.1016/j.ajhg.2015.09.001
2015
Journal Article
Genome-wide autozygosity is associated with lower general cognitive ability
Howrigan, D.P., Simonson, M.A., Davies, G., Harris, S.E., Tenesa, A., Starr, J.M., Liewald, D.C., Deary, I.J., McRae, A., Wright, M.J., Montgomery, G.W., Hansell, N., Martin, N.G., Payton, A., Horan, M., Ollier, W.E., Abdellaoui, A., Boomsma, D.I., DeRosse, P., Knowles, E.E.M., Glahn, D.C., Djurovic, S., Melle, I., Andreassen, O.A., Christoforou, A., Steen, V.M., Hellard, S.L., Sundet, K., Reinvang, I. ... Keller, M.C. (2015). Genome-wide autozygosity is associated with lower general cognitive ability. Molecular Psychiatry, 21 (6), 837-843. doi: 10.1038/mp.2015.120
2015
Journal Article
Population genetic differentiation of height and body mass index across Europe
Robinson, Matthew R., Hemani, Gibran, Medina-Gomez, Carolina, Mezzavilla, Massimo, Esko, Tonu, Shakhbazov, Konstantin, Powell, Joseph E., Vinkhuyzen, Anna, Berndt, Sonja I., Gustafsson, Stefan, Justice, Anne E., Kahali, Bratati, Locke, Adam E., Pers, Tune H., Vedantam, Sailaja, Wood, Andrew R., van Rheenen, Wouter, Andreassen, Ole A., Gasparini, Paolo, Metspalu, Andres, van den Berg, Leonard H., Veldink, Jan H., Rivadeneira, Fernando, Werge, Thomas M., Abecasis, Goncalo R., Boomsma, Dorret I., Chasman, Daniel I., de Geus, Eco J. C., Frayling, Timothy M. ... Visscher, Peter M. (2015). Population genetic differentiation of height and body mass index across Europe. Nature Genetics, 47 (11), 1357-1361. doi: 10.1038/ng.3401
2015
Journal Article
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, Jie, Howie, Bryan, McCarthy, Shane, Memari, Yasin, Walter, Klaudia, Min, Josine L., Danecek, Petr, Malerba, Giovanni, Trabetti, Elisabetta, Zheng, Hou-Feng, Gambaro, Giovanni, Richards, J. Brent, Durbin, Richard, Timpson, Nicholas J., Marchini, Jonathan, Soranzo, Nicole, UK10K Consortium, Evans, David M., Kemp, John P., Visscher, Peter M. and Yang, Jian (2015). Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel. Nature Communications, 6 (1) 8111, 8111.1-8111.9. doi: 10.1038/ncomms9111
2015
Journal Article
3-D Facial Landmark Localization With Asymmetry Patterns and Shape Regression from Incomplete Local Features
Sukno, Federico M., Waddington, John L. and Whelan, Paul F. (2015). 3-D Facial Landmark Localization With Asymmetry Patterns and Shape Regression from Incomplete Local Features. Ieee Transactions On Cybernetics, 45 (9), 1717-1730. doi: 10.1109/TCYB.2014.2359056
2015
Journal Article
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
Yang, Jian, Bakshi, Andrew, Zhu, Zhihong, Hemani, Gibran, Vinkhuyzen, Anna A. E., Lee, Sang Hong, Robinson, Matthew R., Perry, John R. B., Nolte, Ilja M., van Vliet-Ostaptchouk, Jana V., Snieder, Harold, The LifeLines Cohort Study, Esko, Tonu, Milani, Lili, Maegi, Reedik, Metspalu, Andres, Hamsten, Anders, Magnusson, Patrik K. E., Pedersen, Nancy L., Ingelsson, Erik, Soranzo, Nicole, Keller, Matthew C., Wray, Naomi R., Goddard, Michael E. and Visscher, Peter M. (2015). Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index. Nature Genetics, 47 (10), 1114-1120. doi: 10.1038/ng.3390
2015
Journal Article
The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936
Marioni, Riccardo E., Shah, Sonia, McRae, Allan F., Ritchie, Stuart J., Muniz-Terrera, Graciela, Harris, Sarah E., Gibson, Jude, Redmond, Paul, Cox, Simon R., Pattie, Alison, Corley, Janie, Taylor, Adele, Murphy, Lee, Starr, John M., Horvath, Steve, Visscher, Peter M., Wray, Naomi R. and Deary, Ian J. (2015). The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936. International Journal of Epidemiology, 44 (4), 1388-1396. doi: 10.1093/ije/dyu277
2015
Journal Article
The association between intelligence and lifespan is mostly genetic
Arden, Rosalind, Luciano, Michelle, Deary, Ian J., Reynolds, Chandra A., Pedersen, Nancy L., Plassman, Brenda L., McGue, Matt, Christensen, Kaare and Visscher, Peter M. (2015). The association between intelligence and lifespan is mostly genetic. International Journal of Epidemiology, 45 (1), 178-185. doi: 10.1093/ije/dyv112
Supervision
Availability
- Professor Peter Visscher is:
- Not available for supervision
Supervision history
Current supervision
-
Doctor Philosophy
Statistical methods and application to analyses genome and trait data from large biobanks
Principal Advisor
Other advisors: Dr Kathryn Kemper, Professor Loic Yengo
-
Doctor Philosophy
Genetic architecture and evolution of complex traits across populations in humans
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Fleur Garton, Dr Jian Zeng
Completed supervision
-
2022
Doctor Philosophy
Using whole-genome sequence data to elucidate complex trait variation
Principal Advisor
-
2020
Doctor Philosophy
Genetic and genomic analyses on ageing and age-related complex traits
Principal Advisor
Other advisors: Dr Allan McRae
-
2010
Doctor Philosophy
Mitochondrial and autosomal genetic analyses in the Australian population
Principal Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Quantitative genetics approaches to elucidate the role of DNA methylation in complex trait variation
Associate Advisor
Other advisors: Dr Allan McRae
-
2024
Doctor Philosophy
Genomic signature of non-random mating in human complex traits
Associate Advisor
Other advisors: Professor Loic Yengo
-
2024
Doctor Philosophy
Insights into pleiotropic effects across the human genome for complex traits and diseases
Associate Advisor
Other advisors: Dr Allan McRae
-
2022
Doctor Philosophy
Genetic analyses of complex traits using biobank data
Associate Advisor
Other advisors: Professor Naomi Wray
-
2021
Doctor Philosophy
Within and Across Populations Complex Traits and Diseases Prediction Using Summary Statistics from Large-scale Genome-wide Association Studies
Associate Advisor
Other advisors: Professor Loic Yengo
-
2020
Doctor Philosophy
Genetic Differentiation of Human Complex Traits across Worldwide Populations
Associate Advisor
-
2020
Doctor Philosophy
Improving fine-mapping methodology using DNA methylation as a model trait
Associate Advisor
Other advisors: Professor Naomi Wray, Dr Allan McRae
-
2019
Doctor Philosophy
Sexual dimorphism in human gene expression
Associate Advisor
Other advisors: Dr Allan McRae
-
2019
Doctor Philosophy
Systems Genomics of Parkinson's Disease
Associate Advisor
Other advisors: Honorary Professor Jake Gratten
-
2017
Doctor Philosophy
The Genetic Architecture of Psychiatric Disorders
Associate Advisor
Other advisors: Professor Naomi Wray
-
2017
Doctor Philosophy
Characterization of the genetic and environmental factors driving gene expression variability
Associate Advisor
Media
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