Dr David Simmons
Dr

David Simmons

Email: 
Phone: 
+61 7 336 51962

Availability

Dr David Simmons is:
Available for supervision

Fields of research

Animal physiology - cell Biological Sciences Biomedical and Clinical Sciences Cell development, proliferation and death Foetal development and medicine Reproduction Zoology

Qualifications

  • Doctor of Philosophy, W.Ont.

Search Professor David Simmons’s works on UQ eSpace

96 works between 1999 and 2024
All (96) Journal Article (68) Book Chapter (3) Conference Publication (25)

21 - 40 of 96 works

2018

Journal Article

Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration

Tan, Kah Ni, Simmons, David, Carrasco-Pozo, Catalina and Borges, Karin (2018). Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration. Journal of Neurochemistry, 144 (4), 431-442. doi: 10.1111/jnc.14275

Triheptanoin protects against status epilepticus-induced hippocampal mitochondrial dysfunctions, oxidative stress and neuronal degeneration

2017

Journal Article

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip and Forbes, Josephine M. (2017). Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets, 10 (1), 10-24. doi: 10.1080/19382014.2017.1405189

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

2017

Journal Article

Complement C5aR1 signaling promotes polarization and proliferation of embryonic neural progenitor cells through PKCζ

Coulthard, Liam G., Hawksworth, Owen A., Li, Rui, Balachandran, Anushree, Lee, John D., Sepehrband, Farshid, Kurniawan, Nyoman, Jeanes, Angela, Simmons, David G., Wolvetang, Ernst and Woodruff, Trent M. (2017). Complement C5aR1 signaling promotes polarization and proliferation of embryonic neural progenitor cells through PKCζ. Journal of Neuroscience, 37 (22), 5395-5407. doi: 10.1523/JNEUROSCI.0525-17.2017

Complement C5aR1 signaling promotes polarization and proliferation of embryonic neural progenitor cells through PKCζ

2017

Journal Article

Sex differences in rat placental development: from pre-implantation to late gestation

Kalisch-Smith, J. I., Simmons, D. G., Pantaleon, M. and Moritz, K. M. (2017). Sex differences in rat placental development: from pre-implantation to late gestation. Biology of Sex Differences, 8 (1) 17, 17. doi: 10.1186/s13293-017-0138-6

Sex differences in rat placental development: from pre-implantation to late gestation

2017

Journal Article

Molecular analysis of sequence and splice variants of the human SLC13A4 sulfate transporter

Zhang, Zhe, Aung, Zin Thu, Simmons, David G. and Dawson, Paul A. (2017). Molecular analysis of sequence and splice variants of the human SLC13A4 sulfate transporter. Molecular Genetics and Metabolism, 121 (1), 35-42. doi: 10.1016/j.ymgme.2017.03.010

Molecular analysis of sequence and splice variants of the human SLC13A4 sulfate transporter

2017

Journal Article

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse

Bourke, L. M., del Monte-Nieto, G., Outhwaite, J. E., Bharti, V., Pollock, P. M., Simmons, D. G., Adam, A., Hur, S. S. J., Maghzal, G. J., Whitelaw, E., Stocker, R., Suter, C. M., Harvey, R. P. and Harten, S. K. (2017). Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse. Differentiation, 94, 8-20. doi: 10.1016/j.diff.2016.11.004

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse

2017

Journal Article

Review: Alterations in placental glycogen deposition in complicated pregnancies: current preclinical and clinical evidence

Akison, Lisa K., Nitert, Marloes Dekker, Clifton, Vicki L., Moritz, Karen M. and Simmons, David G. (2017). Review: Alterations in placental glycogen deposition in complicated pregnancies: current preclinical and clinical evidence. Placenta, 54, 52-58. doi: 10.1016/j.placenta.2017.01.114

Review: Alterations in placental glycogen deposition in complicated pregnancies: current preclinical and clinical evidence

2017

Journal Article

Review: Nutrient sulfate supply from mother to fetus: placental adaptive responses during human and animal gestation

Dawson, P. A., Richard, K., Perkins, A., Zhang, Z. and Simmons, D. G. (2017). Review: Nutrient sulfate supply from mother to fetus: placental adaptive responses during human and animal gestation. Placenta, 54, 45-51. doi: 10.1016/j.placenta.2017.01.001

Review: Nutrient sulfate supply from mother to fetus: placental adaptive responses during human and animal gestation

2017

Conference Publication

Defining a role of TRPM6 in prenatal development and adult survival of mice

Chubanov, V., Ferioli, S., Wisnowsky, A., Simmons, D. G., Akdogan, B., Mittermeier, L., Zischka, H., Zierler, S., Ryazanov, A. G. and Gudermann, T. (2017). Defining a role of TRPM6 in prenatal development and adult survival of mice. 96th Annual Meeting of the German Physiological Society, Greifswald, Germany, 16–18 March 2017. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing.

Defining a role of TRPM6 in prenatal development and adult survival of mice

2017

Conference Publication

Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain

Woodruff, Trent M., Hawksworth, Owen A., Li, Rui, Balachandran, Anushree, Leel, John D., Sepehrband', Farshid, Kurniawan, Nyoman, Jeanes, Angela, Simmons, David G., Wolvetang, Ernst and Coulthard, Liam G. (2017). Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain. 16th European Meeting on Complement in Human Disease (EMCHD), Copenhagen Denmark, 8-12 September 2017. Kidlington, Oxford United Kingdom: Pergamon Press. doi: 10.1016/j.molimm.2017.06.178

Complement anaphylatoxin receptors have critical physiological functions in the developing mammalian brain

2016

Journal Article

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

Chubanov, Vladimir, Ferioli, Silvia, Wisnowsky, Annika, Simmons, David G., Leitzinger, Christin, Einer, Claudia, Jonas, Wenke, Shymkiv, Yuriy, Bartsch, Harald, Braun, Attila, Akdogan, Banu, Mittermeier, Lorenz, Sytik, Ludmila, Torben, Friedrich, Jurinovic, Vindi, van der Vorst, Emiel P. C., Weber, Christian, Yildirim, Onder A., Sotlar, Karl, Schurmann, Annette, Zierler, Susanna, Zischka, Hans, Ryazanov, Alexey G. and Gudermann, Thomas (2016). Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. eLife, 5 (DECEMBER2016) e20914. doi: 10.7554/eLife.20914

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival

2016

Journal Article

Review: sexual dimorphism in the formation, function and adaptation of the placenta

Kalisch-Smith, J. I., Simmons, D. G., Dickinson, H. and Moritz, K. M. (2016). Review: sexual dimorphism in the formation, function and adaptation of the placenta. Placenta, 54, 10-16. doi: 10.1016/j.placenta.2016.12.008

Review: sexual dimorphism in the formation, function and adaptation of the placenta

2016

Journal Article

IFPA meeting 2015 workshop report I: Placental mitochondrial function, transport systems and epigenetics

Bianco-Miotto, T., Blundell, C., Buckberry, S., Chamley, L., Chong, S., Cottrell, E., Dawson, P., Hanna, C., Holland, O., Lewis, R.M., Moritz, K., Myatt, L., Perkins, A.V., Powell, T., Saffery, R., Sferruzzi-Perri, A., Sibley, C., Simmons, D. and O'Tierney-Ginn, P. F. (2016). IFPA meeting 2015 workshop report I: Placental mitochondrial function, transport systems and epigenetics. Placenta, 48, S3-S6. doi: 10.1016/j.placenta.2015.11.014

IFPA meeting 2015 workshop report I: Placental mitochondrial function, transport systems and epigenetics

2016

Journal Article

Alcohol exposure impairs trophoblast survival and alters subtype-specific gene expression in vitro

Kalisch-Smith, J. I., Outhwaite, J. E., Simmons, D. G., Pantaleon, M. and Moritz, K. M. (2016). Alcohol exposure impairs trophoblast survival and alters subtype-specific gene expression in vitro. Placenta, 46, 87-91. doi: 10.1016/j.placenta.2016.08.080

Alcohol exposure impairs trophoblast survival and alters subtype-specific gene expression in vitro

2015

Journal Article

Interleukin-11 alters placentation and causes preeclampsia features in mice

Winship, Amy L., Koga, Kaori, Menkhorst, Ellen, Van Sinderen, Michelle, Rainczuk, Katarzyna, Nagai, Miwako, Cuman, Carly, Yap, Joanne, Zhang, Jian-Guo, Simmons, David, Young, Morag J. and Dimitriadis, Evdokia (2015). Interleukin-11 alters placentation and causes preeclampsia features in mice. Proceedings of the National Academy of Sciences of the United States of America, 112 (52), 15928-15933. doi: 10.1073/pnas.1515076112

Interleukin-11 alters placentation and causes preeclampsia features in mice

2015

Journal Article

Evidence for multiple sensory circuits in the brain arising from the respiratory system: an anterograde viral tract tracing study in rodents

McGovern, Alice E., Davis-Poynter, Nicholas, Yang, Seung-Kwon, Simmons, David G., Farrell, Michael J. and Mazzone, Stuart B. (2015). Evidence for multiple sensory circuits in the brain arising from the respiratory system: an anterograde viral tract tracing study in rodents. Brain Structure and Function, 220 (6), 3683-3699. doi: 10.1007/s00429-014-0883-9

Evidence for multiple sensory circuits in the brain arising from the respiratory system: an anterograde viral tract tracing study in rodents

2015

Journal Article

Loss of the sulfate transporter Slc13a4 in placenta causes severe fetal abnormalities and death in mice

Rakoczy, Joanna, Zhang, Zhe, Bowling, Francis Gerard, Dawson, Paul Anthony and Simmons, David Gordon (2015). Loss of the sulfate transporter Slc13a4 in placenta causes severe fetal abnormalities and death in mice. Cell Research, 25 (11), 1273-1276. doi: 10.1038/cr.2015.100

Loss of the sulfate transporter Slc13a4 in placenta causes severe fetal abnormalities and death in mice

2015

Journal Article

Genetic ablation of placental sinusoidal trophoblast giant cells causes fetal growth restriction and embryonic lethality

Outhwaite, J. E., McGuire, V. and Simmons, D. G. (2015). Genetic ablation of placental sinusoidal trophoblast giant cells causes fetal growth restriction and embryonic lethality. Placenta, 36 (8), 951-955. doi: 10.1016/j.placenta.2015.05.013

Genetic ablation of placental sinusoidal trophoblast giant cells causes fetal growth restriction and embryonic lethality

2015

Journal Article

The role of C5a receptor signaling in endotoxin-induced miscarriage and preterm birth

Denny, Kerina J., Coulthard, Liam G., Mantovani, Susanna, Simmons, David, Taylor, Stephen M. and Woodruff, Trent M. (2015). The role of C5a receptor signaling in endotoxin-induced miscarriage and preterm birth. American Journal of Reproductive Immunology, 74 (2), 148-155. doi: 10.1111/aji.12386

The role of C5a receptor signaling in endotoxin-induced miscarriage and preterm birth

2015

Journal Article

Placental and fetal cysteine dioxygenase gene expression in mouse gestation

Rakoczy, J., Lee, S., Weerasekera, S. J., Simmons, D. G. and Dawson, P. A. (2015). Placental and fetal cysteine dioxygenase gene expression in mouse gestation. Placenta, 36 (8), 956-959. doi: 10.1016/j.placenta.2015.06.003

Placental and fetal cysteine dioxygenase gene expression in mouse gestation

Past funding

  • 2022 - 2025
    Is SPINT1 a key regulator of placental development? (ARC Discovery Project administered by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2019
    Advanced Brightfield and Fluorescent High Speed and Throughput Slide Scanner for biological, medical, materials science, and agricultural applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2021
    Trophoblast cell-cell fusion in preeclampsia
    NHMRC Project Grant
    Open grant
  • 2013 - 2015
    Chemosensory receptors in heart
    National Heart Foundation of Australia
    Open grant
  • 2012
    Placental clock gene expression in the Spiny Mouse
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2011
    UQ Travel Awards Category 1 - Dr David R C Natale
    UQ Travel Grants Scheme
    Open grant
  • 2010
    Dual channel electrophysiological recordings
    NHMRC Equipment Grant
    Open grant
  • 2010
    Establishment of a digital Scanscope system for virtual microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    In Situ Hybridization Suite for Biomedical Science Researchers
    NHMRC Equipment Grant
    Open grant
  • 2009
    "Real Time PCR Facility for Biomedical Researchers"
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Cell-cell fusion and syncytiotrophoblast formation in the murine placenta
    UQ Early Career Researcher
    Open grant
  • 2009 - 2012
    Interstitially Invasive Trophoblast of the Murine Placenta: Developmental Origins, Functions and Gene Expression.
    NHMRC Project Grant
    Open grant
  • 2008
    Molecular mechanisms and regulation of uterine fluid secretion
    UQ New Staff Research Start-Up Fund
    Open grant

Availability

Dr David Simmons is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Understanding the impact of metformin on one carbon metabolism, placental function and fetal outcomes.

    Associate Advisor

    Other advisors: Dr James Cuffe

Completed supervision

Enquiries

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