Overview
Background
Prof Siskind trained as a psychiatrist in Australia and the United States. He graduated from medicine at the University of Queensland in 1998. After working with Doctors Without Borders in Chechnya in 2000, he became interested in psychiatry. He moved to Boston in 2002, where he did his psychiatry residency at Boston University and a Master of Public Health at Harvard University. He returned to Brisbane in June 2008 as a clinical academic psychiatrist at the Metro South Addiction and Mental Health Service. He completed his Ph.D in Feb 2014. His research interests include clozapine and treatment refractory schizophrenia, the physical health of people with severe and persistent mental illness, supported accommodation, assertive community treatment and mental health services research. He was awarded an NHMRC Investigator Grant as a Leadership Fellow (L1 2027-2031) an Emerging Leadership Fellow (EL2 2021-2025) and an NHMRC Early Career Fellowship (ECF 2016-2019). He has a current CIA MRFF RCRDUN grant looking at treatments to reduce cardiometabolic morbidity among people with schizophrenia. He was the SIRS 2026 Outstanding Clinical and Community Research Award recipient, and was elected to the Australian Academy of Health and Medical Sciences in 2025. He has over 350 peer reviewed publications, including first author in the highly ranked Lancet, World Psychiatry, Lancet Psychiatry, BJPsych, ANZJP, & Schizophrenia Bulletin. He is a named investigator on over $65 million in competitive research grants, with over $9 million as CIA.
Availability
- Professor Dan Siskind is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Schizophrenia
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Physical Health Comorbidity
Research impacts
Prof Siskind's research has had direct, measurable impact on clinical practice and policy. His landmark studies on clozapine-associated neutropenia demonstrated that routine monitoring could safely cease after two years, evidence that has driven the removal of long-term monitoring mandates by regulators — improving safe and quality access to clozapine for more than 2.5 million people globally. His work establishing optimal plasma clozapine reference ranges is now used by pathology providers across Australia, while his findings on antipsychotic-associated metabolic risk and weight gain have been incorporated into international guidelines and adopted into clinical practice, with metformin augmentation now regularly prescribed for patients commencing antipsychotics. His Lancet Psychiatry Commission on physical health in people with mental illness helped set the global agenda for integrating physical and mental healthcare, informing policy from the WHO, OECD, and across multiple countries. As Chair of the INTEGRATE Steering Committee, he led development of the first consensus-based, algorithmic international guidelines for schizophrenia treatment, which have been endorsed by peak bodies. Through sustained engagement with regulators, professional colleges and health services, Prof Siskind has ensured his research translates rapidly from bench to bedside to policy, cementing his reputation as a global leader in schizophrenia care.
Works
Search Professor Dan Siskind’s works on UQ eSpace
2021
Journal Article
Bazett's correction formula overestimates the corrected QT among patients with antipsychotic induced tachycardia
Andric, Teodora, Winckel, Karl, Tanzer, Timothy, Hollingworth, Samantha, Isoardi, Katherine and Siskind, Dan (2021). Bazett's correction formula overestimates the corrected QT among patients with antipsychotic induced tachycardia. Schizophrenia Research, 231, 22-23. doi: 10.1016/j.schres.2021.02.022
2021
Conference Publication
VARENICLINE, BUPROPION AND NICOTINE REPLACEMENT THERAPY FOR SMOKING CESSATION AMONG PEOPLE WITH SCHIZOPHRENIA: A SYSTEMATIC REVIEW AND META-ANALYSIS
Wu, B. T., Wong, T. T., Siskind, D. and Kisely, S. (2021). VARENICLINE, BUPROPION AND NICOTINE REPLACEMENT THERAPY FOR SMOKING CESSATION AMONG PEOPLE WITH SCHIZOPHRENIA: A SYSTEMATIC REVIEW AND META-ANALYSIS. LONDON: SAGE PUBLICATIONS LTD.
2021
Journal Article
Characteristics of people on long-acting injectable antipsychotics in Australia: Data from the 2010 National Survey of High Impact Psychosis
Suetani, Shuichi, Siskind, Dan, Phillipou, Andrea, Waterreus, Anna, Morgan, Vera A. and Castle, David (2021). Characteristics of people on long-acting injectable antipsychotics in Australia: Data from the 2010 National Survey of High Impact Psychosis. Australian and New Zealand Journal of Psychiatry, 55 (10), 958-975. doi: 10.1177/00048674211009602
2021
Journal Article
Does switching antipsychotics ameliorate weight gain in patients with severe mental illness? A systematic review and meta-analysis
Siskind, Dan, Gallagher, Erin, Winckel, Karl, Hollingworth, Samantha, Kisely, Steve, Firth, Joseph, Correll, Christoph U. and Marteene, Wade (2021). Does switching antipsychotics ameliorate weight gain in patients with severe mental illness? A systematic review and meta-analysis. Schizophrenia Bulletin, 47 (4), 948-958. doi: 10.1093/schbul/sbaa191
2021
Journal Article
Characteristics and definitions of ultra-treatment-resistant schizophrenia – A systematic review and meta-analysis
Campana, Mattia, Falkai, Peter, Siskind, Dan, Hasan, Alkomiet and Wagner, Elias (2021). Characteristics and definitions of ultra-treatment-resistant schizophrenia – A systematic review and meta-analysis. Schizophrenia Research, 228, 218-226. doi: 10.1016/j.schres.2020.12.002
2021
Journal Article
A systematic review and meta-analysis of the association between clozapine and norclozapine serum levels and peripheral adverse drug reactions
Tan, Madeleine S. A., Honarparvar, Faraz, Falconer, James R., Parekh, Harendra S., Pandey, Preeti and Siskind, Dan J. (2021). A systematic review and meta-analysis of the association between clozapine and norclozapine serum levels and peripheral adverse drug reactions. Psychopharmacology, 238 (3), 615-637. doi: 10.1007/s00213-020-05746-y
2021
Journal Article
Metformin reduces 12-month change in body weight among people newly commenced on clozapine: a retrospective naturalistic cohort study
Spokes, Jessica, Hollingworth, Samantha, Winckel, Karl, Kisely, Steve, Baker, Andrea, Cosgrove, Peter and Siskind, Dan (2021). Metformin reduces 12-month change in body weight among people newly commenced on clozapine: a retrospective naturalistic cohort study. Therapeutic Advances in Psychopharmacology, 11 20451253211000609, 1-7. doi: 10.1177/20451253211000609
2021
Journal Article
Medicinal psychedelics for mental health and addiction: advancing research of an emerging paradigm
Perkins, Daniel, Sarris, Jerome, Rossell, Susan, Bonomo, Yvonne, Forbes, David, Davey, Christopher, Hoyer, Daniel, Loo, Colleen, Murray, Greg, Hood, Sean, Schubert, Violeta, Galvão-Coelho, Nicole Leite, O’Donnell, Meaghen, Carter, Olivia, Liknaitzky, Paul, Williams, Martin, Siskind, Dan, Penington, David, Berk, Michael and Castle, David (2021). Medicinal psychedelics for mental health and addiction: advancing research of an emerging paradigm. Australian and New Zealand Journal of Psychiatry, 55 (12) 0004867421998785, 4867421998785-1133. doi: 10.1177/0004867421998785
2020
Journal Article
Maximizing the Uptake of a COVID-19 Vaccine in People With Severe Mental Illness A Public Health Priority
Warren, Nicola, Kisely, Steve and Siskind, Dan (2020). Maximizing the Uptake of a COVID-19 Vaccine in People With Severe Mental Illness A Public Health Priority. JAMA Psychiatry, 78 (6), 589-590. doi: 10.1001/jamapsychiatry.2020.4396
2020
Journal Article
Appraisal of physical health guidelines for severe mental illness
Friend, Nadia, Hughes, Jade, Kisely, Steve, Kumar, Ratika and Siskind, Dan (2020). Appraisal of physical health guidelines for severe mental illness. Australian Health Review, 44 (6), 904-915. doi: 10.1071/AH20080
2020
Conference Publication
Can monitoring clozapine and norclozapine levels reduce the occurrence of peripheral ADRs?
Tan, Madeleine S. A., Honarparvar, Faraz , Falconer, James R., Parekh, Harendra S., Pandey, Preeti and Siskind, Dan J. (2020). Can monitoring clozapine and norclozapine levels reduce the occurrence of peripheral ADRs?. ASCEPT-APSA Joint Virtual Scientific Meeting, Hamilton Central, QLD, Australia, 24-26 November 2020.
2020
Conference Publication
Therapeutic drug monitoring as a tool for clozapine therapy in minimising peripheral ADRs
Tan, Madeleine , Honarparvar, Faraz , Falconer, James , Parekh, Harendra , Pandey, Preeti and Siskind, Dan (2020). Therapeutic drug monitoring as a tool for clozapine therapy in minimising peripheral ADRs. Australian Society for Medical Research (ASMR) Queensland Post Graduate Students Virtual Scientific Symposium, Sydney, NSW Australia, 10-11 November 2020.
2020
Journal Article
Clozapine Combination and Augmentation Strategies in Patients with Schizophrenia - Recommendations from an International Expert Survey among the Treatment Response and Resistance in Psychosis (TRRIP) Working Group
Wagner, Elias, Kane, John M., Correll, Christoph U., Howes, Oliver, Siskind, Dan, Honer, William G., Lee, Jimmy, Falkai, Peter, Schneider-Axmann, Thomas and Hasan, Alkomiet (2020). Clozapine Combination and Augmentation Strategies in Patients with Schizophrenia - Recommendations from an International Expert Survey among the Treatment Response and Resistance in Psychosis (TRRIP) Working Group. Schizophrenia Bulletin, 46 (6), 1459-1470. doi: 10.1093/schbul/sbaa060
2020
Journal Article
CBTp for people with treatment refractory schizophrenia on clozapine: a systematic review and meta-analysis
Todorovic, Aleksandar, Lal, Sweta, Dark, Frances, De Monte, Veronica, Kisely, Steve and Siskind, Dan (2020). CBTp for people with treatment refractory schizophrenia on clozapine: a systematic review and meta-analysis. Journal of Mental Health, 32 (1), 1-8. doi: 10.1080/09638237.2020.1836558
2020
Journal Article
Quetiapine withdrawal: a systematic review
Monahan, Katherine, Cuzens-Sutton, Jaimie, Siskind, Dan and Kisely, Steve (2020). Quetiapine withdrawal: a systematic review. Australian and New Zealand Journal of Psychiatry, 55 (8) 0004867420965693, 000486742096569-783. doi: 10.1177/0004867420965693
2020
Journal Article
The association between lithium in drinking water and neuropsychiatric outcomes: a systematic review and meta-analysis from across 2678 regions containing 113 million
Eyre-Watt, Brenton, Mahendran, Eesharnan, Suetani, Shuichi, Firth, Joseph, Kisely, Steve and Siskind, Dan (2020). The association between lithium in drinking water and neuropsychiatric outcomes: a systematic review and meta-analysis from across 2678 regions containing 113 million. Australian and New Zealand Journal of Psychiatry, 55 (2), 139-152. doi: 10.1177/0004867420963740
2020
Journal Article
Phenelzine discontinuation: a bitter pill to swallow
Smith, Lesley and Siskind, Dan (2020). Phenelzine discontinuation: a bitter pill to swallow. Australian and New Zealand Journal of Psychiatry, 55 (8), 4867420965700-832. doi: 10.1177/0004867420965700
2020
Conference Publication
Development and optimization of clozapine-loaded PLGA nanoparticles for nose-to-brain delivery using supercritical fluid technology
Tan, Madeleine S. A. , Parekh, Harendra S., Pandey, Preeti , Siskind, Dan J. and Falconer, James R. (2020). Development and optimization of clozapine-loaded PLGA nanoparticles for nose-to-brain delivery using supercritical fluid technology. 7th FIP Pharmaceutical Sciences World Congress, The Hague, Netherlands, 4-6 October 2020.
2020
Journal Article
A meta-review of “lifestyle psychiatry”: the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders
Firth, Joseph, Solmi, Marco, Wootton, Robyn E., Vancampfort, Davy, Schuch, Felipe B., Hoare, Erin, Gilbody, Simon, Torous, John, Teasdale, Scott B., Jackson, Sarah E., Smith, Lee, Eaton, Melissa, Jacka, Felice N., Veronese, Nicola, Marx, Wolfgang, Ashdown-Franks, Garcia, Siskind, Dan, Sarris, Jerome, Rosenbaum, Simon, Carvalho, André F. and Stubbs, Brendon (2020). A meta-review of “lifestyle psychiatry”: the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders. World Psychiatry, 19 (3), 360-380. doi: 10.1002/wps.20773
2020
Journal Article
A systematic review and meta-analysis of predictors and outcomes of community treatment orders in Australia and New Zealand
Kisely, Steve, Yu, Dong, Maehashi, Saki and Siskind, Dan (2020). A systematic review and meta-analysis of predictors and outcomes of community treatment orders in Australia and New Zealand. Australian and New Zealand Journal of Psychiatry, 55 (7) 0004867420954286, 000486742095428-665. doi: 10.1177/0004867420954286
Funding
Current funding
Supervision
Availability
- Professor Dan Siskind is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
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Doctor Philosophy
Food and nutrition security in individuals with severe mental illness
Principal Advisor
Other advisors: Dr Urska Arnautovska
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Doctor Philosophy
Manifestations, impacts, and clinical implications of physical multimorbidity in people living with severe mental illness
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Steve Kisely
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Master Philosophy
A quantitative and qualitative study of forensic orders in Queensland
Associate Advisor
Other advisors: Professor Steve Kisely, Dr Claudia Bull, Dr Mike Trott
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Doctor Philosophy
Smoking Cessation in People with a Serious Mental Illness
Associate Advisor
Other advisors: Professor Steve Kisely, Professor Coral Gartner
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Doctor Philosophy
Measuring cognitive flexibility in rodents
Associate Advisor
Other advisors: Professor Thomas Burne
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Doctor Philosophy
Management of myocarditis among people with schizophrenia commencing clozapine
Associate Advisor
Other advisors: Associate Professor Nicola Warren
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Doctor Philosophy
Genetic determinants of treatment outcomes in mental health: harnessing the shared genetic etiology of mental disorders for precision psychiatry.
Associate Advisor
Other advisors: Honorary Professor Sarah Medland
Completed supervision
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2026
Doctor Philosophy
The Quality and Safe Use of Clozapine
Principal Advisor
Other advisors: Associate Professor Nicola Warren, Professor Michael Barras, Professor Steve Kisely
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2025
Doctor Philosophy
Investigating clozapine rechallenge using granulocyte-colony stimulating factor in people previously experiencing clozapine-associated neutropenia.
Principal Advisor
Other advisors: Professor Steve Kisely
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2021
Doctor Philosophy
Psychiatric clinical decision making in anti-NMDA receptor encephalitis
Principal Advisor
Other advisors: Associate Professor Stefan Blum, Professor Steve Kisely
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2024
Doctor Philosophy
The Role of the Gut Microbiome in Psychiatric Illness: From Prenatal Risk Factors to Treatment Resistance
Associate Advisor
Other advisors: Honorary Professor Jake Gratten, Honorary Professor Darryl Eyles
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2023
Doctor Philosophy
Measuring and improving cognition in a rodent model relevant to schizophrenia
Associate Advisor
Other advisors: Dr James Kesby, Professor Thomas Burne
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2022
Doctor Philosophy
Nose-to-Brain Delivery of Clozapine in Sol-Gel Systems
Associate Advisor
Other advisors: Associate Professor Harendra Parekh, Dr Preeti Pandey, Dr James Robert Falconer
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2020
Doctor Philosophy
Exploring the characteristics and service needs of carers for adults with mental illness to inform mental health service planning
Associate Advisor
Other advisors: Associate Professor Meredith Harris
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2020
Doctor Philosophy
Who receives what, from whom, and to what effect at clinically operated, community-based residential mental health rehabilitation for Severe and Persistent Mental Illness in Australia?
Associate Advisor
Other advisors: Associate Professor Meredith Harris
Media
Enquiries
Contact Professor Dan Siskind directly for media enquiries about:
- Cardiometabolic co-morbidity of schizophrenia
- Treatment Refractory Schizophrenia
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