Professor John Fraser
Professor

John Fraser

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Availability

Professor John Fraser is:
Available for supervision

Search Professor John Fraser’s works on UQ eSpace

726 works between 2000 and 2025
All (726) Journal Article (581) Book Chapter (8) Conference Publication (129) Book (1) Other Outputs (4) Edited Outputs (3)

241 - 260 of 726 works

2019

Journal Article

Echocardiographic assessment of myocardial function and mechanics during veno-venous extracorporeal membrane oxygenation

Platts, David G., Shiino, Kenji, Chan, Jonathan, Burstow, Darryl J., Scalia, Gregory M. and Fraser, John F. (2019). Echocardiographic assessment of myocardial function and mechanics during veno-venous extracorporeal membrane oxygenation. Echo Research and Practice, 6 (2), 25-35. doi: 10.1530/ERP-18-0071

Echocardiographic assessment of myocardial function and mechanics during veno-venous extracorporeal membrane oxygenation

2019

Journal Article

Steps to enhance safety of tracheostomy on ECMO

Grewal, Jatinder, Sutt, Anna-Liisa, Shekar, Kiran and Fraser, John F. (2019). Steps to enhance safety of tracheostomy on ECMO. Journal of Intensive Care Medicine, 2019, 088506661985107-2. doi: 10.1177/0885066619851074

Steps to enhance safety of tracheostomy on ECMO

2019

Journal Article

Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model

Dhanani, Jayesh A., Diab, Sara, Chaudhary, Jivesh, Cohen, Jeremy, Parker, Suzanne L., Wallis, Steven C., Boidin, Clément, Barnett, Adrian, Chew, Michelle, Roberts, Jason A. and Fraser, John F. (2019). Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model. Anesthesiology, 131 (2), 1-355. doi: 10.1097/ALN.0000000000002752

Lung Pharmacokinetics of Tobramycin by Intravenous and Nebulized Dosing in a Mechanically Ventilated Healthy Ovine Model

2019

Journal Article

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy

Adiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Tesar, Peter, Naidoo, Rishendran, Rapchuk, Ivan, Belz, Stephen, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2019). Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy. Methods and Protocols, 2 (2) 38, 38-12. doi: 10.3390/mps2020038

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacotherapy

2019

Journal Article

Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation

Shekar, Kiran, Grewal, Jatinder, Sutt, Anna Lisa and Fraser, John (2019). Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation. ASAIO journal (American Society for Artificial Internal Organs : 1992), 65 (4), e44-e45. doi: 10.1097/MAT.0000000000000969

Individualizing Sedation in Acute Respiratory Distress Syndrome Patients on Extracorporeal Membrane Oxygenation

2019

Conference Publication

Coronary artery bypass grafting surgery is associated with immunoparalysis of monocytes and dendritic cells

Perros, Alexis J., Esguerra-Lallen, Arlanna, Rooks, Kelly, Chong, Fenny N., Engkilde-Pedersen, Sanne, Faddy, Helen M., Hewlett, Elise, Naidoo, Rishendran, Tung, John-Paul, Fraser, John F., Tesar, Peter, Ziegenfuss, Marc, Smith, Susan, O'Brien, Donalee, Flower, Robert L. and Dean, Melinda M. (2019). Coronary artery bypass grafting surgery is associated with immunoparalysis of monocytes and dendritic cells. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.182.69

Coronary artery bypass grafting surgery is associated with immunoparalysis of monocytes and dendritic cells

2019

Journal Article

Evaluation of an intraventricular balloon pump for short‐term support of patients with heart failure

Boone, Alice C., Gregory, Shaun D., Wu, Eric L., Stephens, Andrew, Liao, Sam, Pauls, Jo P., Salamonsen, Robert, Fraser, John and Tansley, Geoff D. (2019). Evaluation of an intraventricular balloon pump for short‐term support of patients with heart failure. Artificial Organs, 43 (9) aor.13454, 860-869. doi: 10.1111/aor.13454

Evaluation of an intraventricular balloon pump for short‐term support of patients with heart failure

2019

Journal Article

Mesenchymal stem cells may ameliorate inflammation in an ex vivo model of extracorporeal membrane oxygenation

von Bahr, Viktor, Millar, Jonathan E., Malfertheiner, Maximillian V., Ki, Katrina K., Passmore, Margaret R., Bartnikowski, Nicole, Redd, Meredith A., Cavaye, Michael, Suen, Jacky Y., McAuley, Danny F. and Fraser, John F. (2019). Mesenchymal stem cells may ameliorate inflammation in an ex vivo model of extracorporeal membrane oxygenation. Perfusion, 34 (1_suppl), 15-21. doi: 10.1177/0267659119830857

Mesenchymal stem cells may ameliorate inflammation in an ex vivo model of extracorporeal membrane oxygenation

2019

Journal Article

A Review of Coronary Artery Bypass Grafting in the Indigenous Australian Population

Wiemers, Paul D., Fraser, John F., Marney, Lucy, Yadav, Sumit and Tam, Robert (2019). A Review of Coronary Artery Bypass Grafting in the Indigenous Australian Population. Heart Lung and Circulation, 28 (4), 530-538. doi: 10.1016/j.hlc.2018.08.007

A Review of Coronary Artery Bypass Grafting in the Indigenous Australian Population

2019

Journal Article

Effect of ex vivo extracorporeal membrane oxygenation flow dynamics on immune response

Ki, Katrina K., Passmore, Margaret R., Chan, Chris Hoi Houng, Malfertheiner, Maximillian V, Bouquet, Mahe, Cho, Hwa Jin, Suen, Jacky Y. and Fraser, John F. (2019). Effect of ex vivo extracorporeal membrane oxygenation flow dynamics on immune response. Perfusion, 34 (1_suppl), 5-14. doi: 10.1177/0267659119830012

Effect of ex vivo extracorporeal membrane oxygenation flow dynamics on immune response

2019

Journal Article

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

Passmore, Margaret R., Obonyo, Nchafatso G., Byrne, Liam, Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Fung, Yoke L., Spanevello, Michelle M., Fauzi, Mohd H., Pedersen, Sanne E., Simonova, Gabriela, Anstey, Chris M., Shekar, Kiran, Tung, John-Paul, Maitland, Kathryn and Fraser, John F. (2019). Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock. Thrombosis Research, 176, 39-45. doi: 10.1016/j.thromres.2019.02.015

Fluid resuscitation with 0.9% saline alters haemostasis in an ovine model of endotoxemic shock

2019

Journal Article

Respiratory support for infants with bronchiolitis, a narrative review of the literature

Franklin, Donna, Fraser, John F. and Schibler, Andreas (2019). Respiratory support for infants with bronchiolitis, a narrative review of the literature. Paediatric Respiratory Reviews, 30, 16-24. doi: 10.1016/j.prrv.2018.10.001

Respiratory support for infants with bronchiolitis, a narrative review of the literature

2019

Journal Article

Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

Millar, Jonathan E., Bartnikowski, Nicole, von Bahr, Viktor, Malfertheiner, Maximilian V., Obonyo, Nchafatso G., Belliato, Mirko, Suen, Jacky Y., Combes, Alain, McAuley, Daniel F., Lorusso, Roberto and Fraser, John F. (2019). Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models. Intensive Care Medicine Experimental, 7 (1) 18, 18. doi: 10.1186/s40635-019-0232-7

Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

2019

Journal Article

Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience

Grewal, Jatinder, Sutt, Anna-Liisa, Cornmell, George, Shekar, Kiran and Fraser, John (2019). Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience. Journal of Intensive Care Medicine, 35 (11), 1153-1161. doi: 10.1177/0885066619837939

Safety and putative benefits of tracheostomy tube placement in patients on extracorporeal membrane oxygenation: a single-center experience

2019

Journal Article

Endothelialized flow models for blood transfusion research

Ng, Monica S. Y., Suen, Jacky Y., Tung, John-Paul and Fraser, John F. (2019). Endothelialized flow models for blood transfusion research. Haematologica, 104 (3), 428-434. doi: 10.3324/haematol.2018.205203

Endothelialized flow models for blood transfusion research

2019

Journal Article

Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation

Fanning, Jonathon P., Hoe, Louise E. See, Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky Y. and Fraser, John F. (2019). Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation. The American Journal of Cardiology, 123 (3), 434-439. doi: 10.1016/j.amjcard.2018.10.022

Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation

2019

Journal Article

The Australasian resuscitation in sepsis evaluation: FLUid or vasopressors in emergency department sepsis, a multicentre observational study (ARISE FLUIDS observational study): rationale, methods and analysis plan

Keijzers, Gerben, Macdonald, Stephen P. J., Udy, Andrew A., Arendts, Glenn, Bailey, Michael, Bellomo, Rinaldo, Blecher, Gabriel E., Burcham, Jonathon, Delaney, Anthony, Coggins, Andrew R., Fatovich, Daniel M., Fraser, John F., Harley, Amanda, Jones, Peter, Kinnear, Fran, May, Katya, Peake, Sandra, Taylor, David McD, Williams, Julian and Williams, Patricia (2019). The Australasian resuscitation in sepsis evaluation: FLUid or vasopressors in emergency department sepsis, a multicentre observational study (ARISE FLUIDS observational study): rationale, methods and analysis plan. Emergency Medicine Australasia, 31 (1), 90-96. doi: 10.1111/1742-6723.13223

The Australasian resuscitation in sepsis evaluation: FLUid or vasopressors in emergency department sepsis, a multicentre observational study (ARISE FLUIDS observational study): rationale, methods and analysis plan

2019

Journal Article

Sepsis: changing definitions, unchanging treatment

Obonyo, Nchafatso Gikenyi, Schlapbach, Luregn Jan and Fraser, John Francis (2019). Sepsis: changing definitions, unchanging treatment. Frontiers in Pediatrics, 6 (JAN) 425, 425. doi: 10.3389/fped.2018.00425

Sepsis: changing definitions, unchanging treatment

2019

Journal Article

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

2019

Journal Article

Sedatives, analgesics, and antipsychotics in tracheostomised intensive care unit patients – Is less more?

Sutt, Anna-Liisa, Hay, Karen, Kinneally, Toni, Fisquet, Stephanie and Fraser, John F. (2019). Sedatives, analgesics, and antipsychotics in tracheostomised intensive care unit patients – Is less more?. Australian Critical Care, 33 (5), 407-411. doi: 10.1016/j.aucc.2018.12.004

Sedatives, analgesics, and antipsychotics in tracheostomised intensive care unit patients – Is less more?

Current funding

  • 2025 - 2027
    REDEEM: A Randomised Controlled Trial of ECMO to Desedate, Extubate Early and Mobilise in severe acute respiratory infection (MRFF RCRDUN led by Monash University)
    Monash University
    Open grant
  • 2025 - 2027
    Load Incorporating Cardiac Assessment by Echocardiography to Refine Outcome Predictions In Patients with SEpsis: Prospective Multicentre Study (LIAISE study)
    TPCH Foundation Innovation Grants
    Open grant
  • 2025 - 2027
    Towards Equitable Monitoring in the ICU - Reducing Racial Bias of Pulse Oximeters with Corrective Algorithms
    TPCH Foundation Innovation Grants
    Open grant
  • 2024 - 2029
    Research Equipment for the Critical Care Research Group at IMB
    The Common Good and the Sheila & Bernard Joel Life Saving Medical Equipment Foundation
    Open grant
  • 2024 - 2028
    The HEART REHAB Clinical Trials: Therapeutics to Protect the Human Heart
    MRFF Frontier Health and Medical Research Program administered by AusIndustry
    Open grant
  • 2024 - 2026
    ALL IN - AI and Laboratory Led IdentificatioN of PASC
    NHMRC MRFF Post-Acute Sequelae of COVID-19
    Open grant
  • 2024 - 2026
    Addressing deficiencies of current ECMO with an innovative pulsatile flow technology (ADEPT)
    National Heart Foundation Vanguard Grant
    Open grant
  • 2023 - 2025
    Effect of mitochondrial transplantation following hypothermic machine perfusion on donor heart ischemic time
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2025
    Heart Ex Vivo Perfusion
    The Donald & Joan Wilson Foundation Ltd
    Open grant
  • 2023 - 2028
    Generating new evidence to reduce complications and improve the safety and efficacy of extracorporeal membrane oxygenation in patients with severe cardiac and respiratory failure (Ex led by Monash)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant
  • 2020 - 2026
    Transfusion Triggers in Cardiac Surgery Australia trial (TRICS-IV) (MRFF ICTC Grant Led by University of Melbourne)
    University of Melbourne
    Open grant

Past funding

  • 2024
    The BLENDER Trial - Blend to Limit Oxygen in ECMO: A randomised Controlled Registry Trial (Monash University administered LCTRC grant)
    Monash University
    Open grant
  • 2024
    2023 Equipment grant - OxyLiteTM/OxyFloTM combined 4 Channel tissue pO2 and temperature monitor with touch screen
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2024
    A Comparative Assessment of the Distribution of Antibiotics in Pulsatile- and Continuous-Flow Venoarterial Extracorporeal Membrane Oxygenation: An Ovine Model of Severe Cardiogenic Shock
    Prince Charles Hospital Foundation
    Open grant
  • 2022 - 2024
    Developing FXIIa inhibitors as next-generation anticoagulants
    NHMRC Development Grant
    Open grant
  • 2021
    Equipment Grant - ULT (ultra low temperature) -80 degree freezer
    Prince Charles Hospital Foundation
    Open grant
  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2019 - 2022
    Nitric Oxide to improve recovery and survival in neonates and children on Extracorporeal Life Support - a pilot randomized controlled trial (the NECTAR trial)
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2021
    Novel fluid alternatives to blood transfusion to treat acute and chronic blood loss
    National Blood Authority
    Open grant
  • 2019
    Advanced Haemodynamic Monitoring for Large Animal Experimentation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2021
    The EXCEL Project: A collaborative approach to improve outcomes of Australian patients with acute heart failure and cardiac arrest requiring... (NHMRC Partnership Projects led by Monash University)
    Monash University
    Open grant
  • 2018 - 2022
    The Dead Heart Project: When is a 'dead' heart truly dead?
    NHMRC Project Grant
    Open grant
  • 2017 - 2020
    High flow nasal cannula treatment for infants and children with acute respiratory failure
    Thrasher Research Fund
    Open grant
  • 2017 - 2018
    The impact of extracorporeal membrane oxygenation (ECMO) on the activities of drug enzymes that affect the pharmacokinetics and therapeutic outcomes of clinically important drugs
    Prince Charles Hospital Foundation
    Open grant
  • 2016
    Assessment of cerebral microcirculation after severe head injury when exposed to acute anaemia
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016 - 2017
    Does inhaled tobramycin distribute effectively into the lungs? A comparative study using radiolabelled tobramycin.
    Royal Brisbane and Women's Hospital
    Open grant
  • 2016 - 2018
    Stemming devastating neurological injury caused by transcatheter aortic valve implantation (TAVI): First-in-man application of two novel neuroprotective strategies to an interventional cardiology...
    National Heart Foundation of Australia
    Open grant
  • 2015 - 2018
    Resuscitation in Endotoxaemic Shock - Understanding Sepsis (RESUS)
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Cerebral Microcirculation in Head Injury During Normovolemic Anemia: An Experimental Model
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015 - 2017
    High Flow Cannula Therapy in Bronchiolitis, a Randomised Controlled Trial
    NHMRC Project Grant
    Open grant
  • 2014 - 2021
    Centre for Research Excellence in Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS)
    NHMRC Centres of Research Excellence
    Open grant
  • 2014 - 2015
    Pilot study: High Flow Nasal Cannula (HFNC) therapy in infants with Bronchiolitis, a randomised controlled trial in regional emergency departments
    Queensland Emergency Medicine Research Foundation
    Open grant
  • 2014 - 2015
    Consequences of Bleeding on Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2014
    Assessment of the Cerebral Microcirculation after Head Injury
    DHF Establishment Grants
    Open grant
  • 2013 - 2015
    Assessment of the Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012
    Facilitating School of Medicine as a central coordinator of global pharmacokinetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    Investigation of the cerebral microcirculation after head injury : pilot study
    Brain Foundation
    Open grant
  • 2011 - 2013
    The unholy alliance between extracorporeal circuitry and the transfusion medicine: characterising inflammation and injury (NHMRC Project Grant led by The Prince Charles Hospital)
    Prince Charles Hospital
    Open grant
  • 2010 - 2011
    Novel Infusion Decision Support System for Circulatory Management of Intensive Care Patients
    UQ FirstLink Scheme
    Open grant
  • 2010 - 2011
    Novel Physiological Control of Bionic Hearts
    UQ FirstLink Scheme
    Open grant
  • 2009
    Improving outcomes post burn injury
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    Hyperpolarized helium MRI to quantify regional lung damage and ventilation for improvement of recruitment strategy
    NHMRC Project Grant
    Open grant
  • 2006 - 2012
    Endothelins in brain stem death - Effects on the right ventricle and Ischaemia repurfusion.
    Prince Charles Hospital Foundation
    Open grant
  • 2005 - 2007
    Studying factors from fetal sheep to test if they can reduce scarring in childhood burns
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2005
    Therapeutic strategies to prevent acute respiratory distress syndrome in patients with smoke inhalation. The effect of recombinant activated protein C (rhAPC) on acute lung injury....
    Royal Children's Hospital Foundation
    Open grant
  • 2001 - 2003
    Fetal wound healing: An ovine model for scarless burns recovery in children.
    Australian and New Zealand Burn Association Ltd
    Open grant
  • 2001 - 2002
    Fetal wound healing: An ovine model for scarless burns recovery in children
    Mayne Bequest Fund
    Open grant
  • 2001 - 2003
    CONROD - RACS TRAUMA FELLOWSHIP: Therapeutic strategies to prevent ARDS in patients with smoke inhalation.
    Royal Australasian College of Surgeons
    Open grant

Availability

Professor John Fraser is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Novel Right Heart Assessment by Speckle Tracking Echocardiography

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Development of Speckle-Tracking Echocardiographic strain accounting for cardiac loading conditions

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Vascular Endothelial Injury, Repair and Preconditioning in the Artificial Circulation

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    ICU of the Future

    Principal Advisor

    Other advisors: Associate Professor Allison Mandrusiak

  • Doctor Philosophy

    Fibrinogen Replacement in Traumatic Haemorrhage

    Principal Advisor

  • Doctor Philosophy

    Vascular Endothelial Injury, Repair and Preconditioning in the Artificial Circulation

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Load-Independent Right Ventricular Assessment by Echocardiography

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Development of a novel pulmonary imaging technology for mechanically ventilated patients.

    Principal Advisor

    Other advisors: Dr Gianluigi Li Bassi

  • Doctor Philosophy

    The ICU of the future project ¿ can redesigning the ICU environment improve patient outcomes?

    Principal Advisor

    Other advisors: Associate Professor Allison Mandrusiak

  • Doctor Philosophy

    Examining healthcare access and outcomes for Aboriginal and Torres Strait Islander people with rheumatic heart disease in Queensland.

    Associate Advisor

Completed supervision

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