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Professor John Fraser
Professor

John Fraser

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Overview

Availability

Professor John Fraser is:
Available for supervision

Works

Search Professor John Fraser’s works on UQ eSpace

730 works between 2000 and 2025

181 - 200 of 730 works

2020

Conference Publication

Validation of the Delirium Decision Support Tool

Eeles, E., Dakin, L., Fraser, J., Ling, C., Kaur, P. and Dissanayaka, N. (2020). Validation of the Delirium Decision Support Tool. DCRC Online Symposia: Anxiety and Depression in Dementia Research Network., Online, 11 November 2020.

Validation of the Delirium Decision Support Tool

2020

Journal Article

ECMO during the COVID-19 pandemic: When is it justified?

Heinsar, Silver, Peek, Giles J. and Fraser, John F. (2020). ECMO during the COVID-19 pandemic: When is it justified?. Critical Care, 24 (1) 650, 650. doi: 10.1186/s13054-020-03386-4

ECMO during the COVID-19 pandemic: When is it justified?

2020

Journal Article

The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline

Rochwerg, Bram, Einav, Sharon, Chaudhuri, Dipayan, Mancebo, Jordi, Mauri, Tommaso, Helviz, Yigal, Goligher, Ewan C., Jaber, Samir, Ricard, Jean-Damien, Rittayamai, Nuttapol, Roca, Oriol, Antonelli, Massimo, Maggiore, Salvatore Maurizio, Demoule, Alexandre, Hodgson, Carol L., Mercat, Alain, Wilcox, M. Elizabeth, Granton, David, Wang, Dominic, Azoulay, Elie, Ouanes-Besbes, Lamia, Cinnella, Gilda, Rauseo, Michela, Carvalho, Carlos, Dessap-Mekontso, Armand, Fraser, John, Frat, Jean-Pierre, Gomersall, Charles, Grasselli, Giacomo ... Burns, Karen E. A. (2020). The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline. Intensive Care Medicine, 46 (12), 2226-2237. doi: 10.1007/s00134-020-06312-y

The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline

2020

Journal Article

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit

Passmore, Margaret R., Ki, Katrina K., Chan, Chris H. H., Lee, Talvin, Bouquet, Mahé, Wood, Emily S., Raman, Sainath, Rozencwajg, Sacha, Burrell, Aidan J. C., McDonald, Charles I., Langguth, Daman, Shekar, Kiran, Malfertheiner, Maximilian V., Fraser, John F. and Suen, Jacky Y. (2020). The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit. Artificial Organs, 44 (12) aor.13771, 1276-1285. doi: 10.1111/aor.13771

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit

2020

Journal Article

Airborne spread of SARS-CoV-2 while using high-flow nasal cannula oxygen therapy: myth or reality?

Haymet, Andrew, Li Bassi, Gianluigi and Fraser, John F. (2020). Airborne spread of SARS-CoV-2 while using high-flow nasal cannula oxygen therapy: myth or reality?. Intensive Care Medicine, 46 (12), 2248-2251. doi: 10.1007/s00134-020-06314-w

Airborne spread of SARS-CoV-2 while using high-flow nasal cannula oxygen therapy: myth or reality?

2020

Journal Article

Microvascular dysfunction in septic and dengue shock: pathophysiology and implications for clinical management

McBride, Angela, Chanh, Ho Q., Fraser, John F., Yacoub, Sophie and Obonyo, Nchafatso G. (2020). Microvascular dysfunction in septic and dengue shock: pathophysiology and implications for clinical management. Global Cardiology Science and Practice, 2020 (2) e202029, e202029. doi: 10.21542/gcsp.2020.29

Microvascular dysfunction in septic and dengue shock: pathophysiology and implications for clinical management

2020

Journal Article

Extracorporeal life support for adults with acute respiratory distress syndrome

Combes, Alain, Schmidt, Matthieu, Hodgson, Carol L., Fan, Eddy, Ferguson, Niall D., Fraser, John F., Jaber, Samir, Pesenti, Antonio, Ranieri, Marco, Rowan, Kathryn, Shekar, Kiran, Slutsky, Arthur S. and Brodie, Daniel (2020). Extracorporeal life support for adults with acute respiratory distress syndrome. Intensive Care Medicine, 46 (12), 2464-2476. doi: 10.1007/s00134-020-06290-1

Extracorporeal life support for adults with acute respiratory distress syndrome

2020

Journal Article

The perceived barriers and facilitators to implementation of ECMO services in acute hospitals

Fulcher, Bentley J., Nicholson, Angus J., Linke, Natalie J., Berkovic, Danielle, Hodgson, Carol L., EXCEL Study Investigators and the International ECMO Network and Fraser, John F. (2020). The perceived barriers and facilitators to implementation of ECMO services in acute hospitals. Intensive Care Medicine, 46 (11), 2115-2117. doi: 10.1007/s00134-020-06187-z

The perceived barriers and facilitators to implementation of ECMO services in acute hospitals

2020

Journal Article

Heart transplantation from brain dead donors: a systematic review of animal models

See Hoe, Louise E., Wells, Matthew A., Bartnikowski, Nicole, Obonyo, Nchafatso G., Millar, Jonathan E., Khoo, Aimee, Ki, Katrina K., Shuker, Tristan, Ferraioli, Alessandro, Colombo, Sebastiano M., Chan, Wandy, McGiffin, David C., Suen, Jacky Y. and Fraser, John F. (2020). Heart transplantation from brain dead donors: a systematic review of animal models. Transplantation, 104 (11), 2272-2289. doi: 10.1097/tp.0000000000003217

Heart transplantation from brain dead donors: a systematic review of animal models

2020

Journal Article

Ovine red cell concentrates for transfusion research – is the storage lesion comparable to human red cell concentrates?

Simonova, Gabriela, Wellburn, Rebecca, Fung, Yoke Lin, Fraser, John F. and Tung, John‐Paul (2020). Ovine red cell concentrates for transfusion research – is the storage lesion comparable to human red cell concentrates?. Vox Sanguinis, 116 (5) vox.13020, 524-532. doi: 10.1111/vox.13020

Ovine red cell concentrates for transfusion research – is the storage lesion comparable to human red cell concentrates?

2020

Journal Article

Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system

Walweel, K., Skeggs, K., Boon, A. C., See Hoe, L. E., Bouquet, M., Obonyo, N. G., Pedersen, S. E., Diab, S. D., Passmore, M. R., Hyslop, K., Wood, E. S., Reid, J., Colombo, S. M., Bartnikowski, N. J., Wells, M. A., Black, D., Pimenta, L. P., Stevenson, A. K., Bisht, K., Marshall, L., Prabhu, D. A., James, L., Platts, D. G., MacDonald, P. S., McGiffin, D. C., Suen, J. Y. and Fraser, J. F. (2020). Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system. Journal of Biomedical Science, 27 (1) 96, 96. doi: 10.1186/s12929-020-00690-7

Endothelin receptor antagonist improves donor lung function in an ex vivo perfusion system

2020

Journal Article

Apples and oranges: international comparisons of COVID-19 observational studies in ICUs

Millar, Jonathan E., Busse, Reinhard, Fraser, John F., Karagiannidis, Christian and McAuley, Daniel F. (2020). Apples and oranges: international comparisons of COVID-19 observational studies in ICUs. The Lancet Respiratory Medicine, 8 (10), 952-953. doi: 10.1016/S2213-2600(20)30368-4

Apples and oranges: international comparisons of COVID-19 observational studies in ICUs

2020

Journal Article

Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry

Barbaro, Ryan P., MacLaren, Graeme, Boonstra, Philip S., Iwashyna, Theodore J., Slutsky, Arthur S., Fan, Eddy, Bartlett, Robert H., Tonna, Joseph E., Hyslop, Robert, Fanning, Jeffrey J., Rycus, Peter T., Hyer, Steve J., Anders, Marc M., Agerstrand, Cara L., Hryniewicz, Katarzyna, Diaz, Rodrigo, Lorusso, Roberto, Combes, Alain, Brodie, Daniel, Extracorporeal Life Support Organization, Shekar, Kiran and Fraser, John (2020). Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry. Lancet , 396 (10257), 1071-1078. doi: 10.1016/S0140-6736(20)32008-0

Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry

2020

Journal Article

Reply to: MSC-derived exosomes: are they another therapeutic method for ECMO-supported ARDS?

Millar, Jonathan E, Suen, Jacky Y., McAuley, Daniel F., Fraser, John F. and on behalf of all authors of ‘Combined Mesenchymal Stromal Cell Therapy and Extracorporeal Membrane Oxygenation in Acute Respiratory Distress Syndrome: A Controlled Experimental Study in Sheep.’ (2020). Reply to: MSC-derived exosomes: are they another therapeutic method for ECMO-supported ARDS?. American Journal of Respiratory and Critical Care Medicine, 202 (11) rccm.202007-2995LE, 1603-1604. doi: 10.1164/rccm.202007-2995le

Reply to: MSC-derived exosomes: are they another therapeutic method for ECMO-supported ARDS?

2020

Journal Article

First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service

Gc, Vijay S., Franklin, Donna, Whitty, Jennifer A., Dalziel, Stuart R., Babl, Franz E., Schalpbach, Luregn J., Fraser, John F., Craig, Simon, Neutze, Jocelyn, Oakley, Ed and Schibler, Andreas (2020). First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service. Archives of Disease in Childhood, 105 (10), 975-980. doi: 10.1136/archdischild-2019-318427

First-line oxygen therapy with high-flow in bronchiolitis is not cost saving for the health service

2020

Journal Article

Reconceptualizing post-intensive care syndrome: do we need to unpick our PICS?

Flaws, Dylan, Patterson, Susan, Fraser, John, Tronstad, Oystein and Scott, James G (2020). Reconceptualizing post-intensive care syndrome: do we need to unpick our PICS?. Nursing in critical care, 26 (2) 12545, 67-69. doi: 10.1111/nicc.12545

Reconceptualizing post-intensive care syndrome: do we need to unpick our PICS?

2020

Journal Article

Doing time in an Australian ICU; the experience and environment from the perspective of patients and family members

Tronstad, Oystein, Flaws, Dylan, Lye, India, Fraser, John F. and Patterson, Sue (2020). Doing time in an Australian ICU; the experience and environment from the perspective of patients and family members. Australian Critical Care, 34 (3), 254-262. doi: 10.1016/j.aucc.2020.06.006

Doing time in an Australian ICU; the experience and environment from the perspective of patients and family members

2020

Journal Article

Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma

Bouquet, Mahé, Passmore, Margaret R., See Hoe, Louise E., Tung, John-Paul, Simonova, Gabriela, Boon, Ai-Ching and Fraser, John F. (2020). Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma. Journal of Immunological Methods, 486 112835, 112835. doi: 10.1016/j.jim.2020.112835

Development and validation of ELISAs for the quantitation of interleukin (IL)-1β, IL-6, IL-8 and IL-10 in ovine plasma

2020

Journal Article

Acute Immune Response in Venoarterial and Venovenous Extracorporeal Membrane Oxygenation Models of Rats

Cho, Hwa-Jin, Kayumov, Mukhammad, Kim, Dowan, Lee, Kyoseon, Onyekachi, Francis Obiweluozor, Jeung, Kyung-Woon, Kim, Yongsook, Suen, Jacky Y., Fraser, John F. and Jeong, In-Seok (2020). Acute Immune Response in Venoarterial and Venovenous Extracorporeal Membrane Oxygenation Models of Rats. ASAIO Journal, 67 (5), 546-553. doi: 10.1097/MAT.0000000000001265

Acute Immune Response in Venoarterial and Venovenous Extracorporeal Membrane Oxygenation Models of Rats

2020

Journal Article

Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep

Millar, Jonathan E., Bartnikowski, Nicole, Passmore, Margaret R., Obonyo, Nchafatso G, Malfertheiner, Maximillian V., von Bahr, Viktor, Redd, Meredith A., See Hoe, Louise, Ki, Katrina K., Pedersen, Sanne, Boyle, Andrew J., Baillie, J Kenneth, Shekar, Kiran, Palpant, Nathan, Suen, Jacky Y., Matthay, Michael A., McAuley, Daniel F., Fraser, John F. and Combining Extracorporeal Life Support and Cell Therapy in Critical Illness (CELTIC) investigators (2020). Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep. American Journal of Respiratory and Critical Care Medicine, 202 (3) rccm.201911-2143OC, 383-392. doi: 10.1164/rccm.201911-2143oc

Combined mesenchymal stromal cell therapy and ECMO in ARDS: a controlled experimental study in sheep

Funding

Current funding

  • 2025 - 2027
    REDEEM: A Randomised Controlled Trial of ECMO to Desedate, Extubate Early and Mobilise in severe acute respiratory infection (MRFF RCRDUN led by Monash University)
    Monash University
    Open grant
  • 2025 - 2027
    Load Incorporating Cardiac Assessment by Echocardiography to Refine Outcome Predictions In Patients with SEpsis: Prospective Multicentre Study (LIAISE study)
    TPCH Foundation Innovation Grants
    Open grant
  • 2025 - 2027
    Towards Equitable Monitoring in the ICU - Reducing Racial Bias of Pulse Oximeters with Corrective Algorithms
    TPCH Foundation Innovation Grants
    Open grant
  • 2024 - 2029
    Research Equipment for the Critical Care Research Group at IMB
    The Common Good and the Sheila & Bernard Joel Life Saving Medical Equipment Foundation
    Open grant
  • 2024 - 2028
    The HEART REHAB Clinical Trials: Therapeutics to Protect the Human Heart
    MRFF Frontier Health and Medical Research Program administered by AusIndustry
    Open grant
  • 2024 - 2026
    ALL IN - AI and Laboratory Led IdentificatioN of PASC
    NHMRC MRFF Post-Acute Sequelae of COVID-19
    Open grant
  • 2024 - 2026
    Addressing deficiencies of current ECMO with an innovative pulsatile flow technology (ADEPT)
    National Heart Foundation Vanguard Grant
    Open grant
  • 2023 - 2025
    Effect of mitochondrial transplantation following hypothermic machine perfusion on donor heart ischemic time
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2025
    Heart Ex Vivo Perfusion
    The Donald & Joan Wilson Foundation Ltd
    Open grant
  • 2023 - 2028
    Generating new evidence to reduce complications and improve the safety and efficacy of extracorporeal membrane oxygenation in patients with severe cardiac and respiratory failure (Ex led by Monash)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant
  • 2020 - 2026
    Transfusion Triggers in Cardiac Surgery Australia trial (TRICS-IV) (MRFF ICTC Grant Led by University of Melbourne)
    University of Melbourne
    Open grant

Past funding

  • 2024
    The BLENDER Trial - Blend to Limit Oxygen in ECMO: A randomised Controlled Registry Trial (Monash University administered LCTRC grant)
    Monash University
    Open grant
  • 2024
    2023 Equipment grant - OxyLiteTM/OxyFloTM combined 4 Channel tissue pO2 and temperature monitor with touch screen
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2024
    A Comparative Assessment of the Distribution of Antibiotics in Pulsatile- and Continuous-Flow Venoarterial Extracorporeal Membrane Oxygenation: An Ovine Model of Severe Cardiogenic Shock
    Prince Charles Hospital Foundation
    Open grant
  • 2022 - 2024
    Developing FXIIa inhibitors as next-generation anticoagulants
    NHMRC Development Grant
    Open grant
  • 2021
    Equipment Grant - ULT (ultra low temperature) -80 degree freezer
    Prince Charles Hospital Foundation
    Open grant
  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2019 - 2022
    Nitric Oxide to improve recovery and survival in neonates and children on Extracorporeal Life Support - a pilot randomized controlled trial (the NECTAR trial)
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2021
    Novel fluid alternatives to blood transfusion to treat acute and chronic blood loss
    National Blood Authority
    Open grant
  • 2019
    Advanced Haemodynamic Monitoring for Large Animal Experimentation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2021
    The EXCEL Project: A collaborative approach to improve outcomes of Australian patients with acute heart failure and cardiac arrest requiring... (NHMRC Partnership Projects led by Monash University)
    Monash University
    Open grant
  • 2018 - 2022
    The Dead Heart Project: When is a 'dead' heart truly dead?
    NHMRC Project Grant
    Open grant
  • 2017 - 2020
    High flow nasal cannula treatment for infants and children with acute respiratory failure
    Thrasher Research Fund
    Open grant
  • 2017 - 2018
    The impact of extracorporeal membrane oxygenation (ECMO) on the activities of drug enzymes that affect the pharmacokinetics and therapeutic outcomes of clinically important drugs
    Prince Charles Hospital Foundation
    Open grant
  • 2016
    Assessment of cerebral microcirculation after severe head injury when exposed to acute anaemia
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016 - 2017
    Does inhaled tobramycin distribute effectively into the lungs? A comparative study using radiolabelled tobramycin.
    Royal Brisbane and Women's Hospital
    Open grant
  • 2016 - 2018
    Stemming devastating neurological injury caused by transcatheter aortic valve implantation (TAVI): First-in-man application of two novel neuroprotective strategies to an interventional cardiology...
    National Heart Foundation of Australia
    Open grant
  • 2015 - 2018
    Resuscitation in Endotoxaemic Shock - Understanding Sepsis (RESUS)
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Cerebral Microcirculation in Head Injury During Normovolemic Anemia: An Experimental Model
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015 - 2017
    High Flow Cannula Therapy in Bronchiolitis, a Randomised Controlled Trial
    NHMRC Project Grant
    Open grant
  • 2014 - 2021
    Centre for Research Excellence in Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS)
    NHMRC Centres of Research Excellence
    Open grant
  • 2014 - 2015
    Pilot study: High Flow Nasal Cannula (HFNC) therapy in infants with Bronchiolitis, a randomised controlled trial in regional emergency departments
    Queensland Emergency Medicine Research Foundation
    Open grant
  • 2014 - 2015
    Consequences of Bleeding on Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2014
    Assessment of the Cerebral Microcirculation after Head Injury
    DHF Establishment Grants
    Open grant
  • 2013 - 2015
    Assessment of the Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012
    Facilitating School of Medicine as a central coordinator of global pharmacokinetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    Investigation of the cerebral microcirculation after head injury : pilot study
    Brain Foundation
    Open grant
  • 2011 - 2013
    The unholy alliance between extracorporeal circuitry and the transfusion medicine: characterising inflammation and injury (NHMRC Project Grant led by The Prince Charles Hospital)
    Prince Charles Hospital
    Open grant
  • 2010 - 2011
    Novel Infusion Decision Support System for Circulatory Management of Intensive Care Patients
    UQ FirstLink Scheme
    Open grant
  • 2010 - 2011
    Novel Physiological Control of Bionic Hearts
    UQ FirstLink Scheme
    Open grant
  • 2009
    Improving outcomes post burn injury
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    Hyperpolarized helium MRI to quantify regional lung damage and ventilation for improvement of recruitment strategy
    NHMRC Project Grant
    Open grant
  • 2006 - 2012
    Endothelins in brain stem death - Effects on the right ventricle and Ischaemia repurfusion.
    Prince Charles Hospital Foundation
    Open grant
  • 2005 - 2007
    Studying factors from fetal sheep to test if they can reduce scarring in childhood burns
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2005
    Therapeutic strategies to prevent acute respiratory distress syndrome in patients with smoke inhalation. The effect of recombinant activated protein C (rhAPC) on acute lung injury....
    Royal Children's Hospital Foundation
    Open grant
  • 2001 - 2003
    Fetal wound healing: An ovine model for scarless burns recovery in children.
    Australian and New Zealand Burn Association Ltd
    Open grant
  • 2001 - 2002
    Fetal wound healing: An ovine model for scarless burns recovery in children
    Mayne Bequest Fund
    Open grant
  • 2001 - 2003
    CONROD - RACS TRAUMA FELLOWSHIP: Therapeutic strategies to prevent ARDS in patients with smoke inhalation.
    Royal Australasian College of Surgeons
    Open grant

Supervision

Availability

Professor John Fraser is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Vascular Endothelial Injury, Repair and Preconditioning in the Artificial Circulation

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Fibrinogen Replacement in Traumatic Haemorrhage

    Principal Advisor

  • Doctor Philosophy

    Load-Independent Right Ventricular Assessment by Echocardiography

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Development of a novel pulmonary imaging technology for mechanically ventilated patients.

    Principal Advisor

    Other advisors: Dr Gianluigi Li Bassi

  • Doctor Philosophy

    The ICU of the future project ¿ can redesigning the ICU environment improve patient outcomes?

    Principal Advisor

    Other advisors: Associate Professor Allison Mandrusiak

  • Doctor Philosophy

    Examining healthcare access and outcomes for Aboriginal and Torres Strait Islander people with rheumatic heart disease in Queensland.

    Associate Advisor

Completed supervision

Media

Enquiries

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