Professor John Fraser
Professor

John Fraser

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Availability

Professor John Fraser is:
Available for supervision

Search Professor John Fraser’s works on UQ eSpace

726 works between 2000 and 2025
All (726) Journal Article (581) Book Chapter (8) Conference Publication (129) Book (1) Other Outputs (4) Edited Outputs (3)

281 - 300 of 726 works

2018

Journal Article

Permissive hypercapnia, alveolar recruitment and low airway pressure (PHARLAP): A protocol for a phase 2 trial in patients with acute respiratory distress syndrome

Hodgson, Carol, Cooper, David Jamie, Arabi, Yaseen, Bennett, Victoria, Bersten, Andrew, Brickell, Kathy, Davies, Andrew, Fahey, Ciara, Fraser, John, McGuinness, Shay, Murray, Lynne, Parke, Rachael, Tuxen, David, Vallance, Shirley, Young, Meredith and Nichol, Alistair D. (2018). Permissive hypercapnia, alveolar recruitment and low airway pressure (PHARLAP): A protocol for a phase 2 trial in patients with acute respiratory distress syndrome. Critical Care and Resuscitation, 20 (2), 139-149.

Permissive hypercapnia, alveolar recruitment and low airway pressure (PHARLAP): A protocol for a phase 2 trial in patients with acute respiratory distress syndrome

2018

Journal Article

Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation

Dhanani, Jayesh A., Tang, Patrician, Wallis, Steven C., Parker, Suzanne L., Pandey, Preeti, Fraser, John F., Cohen, Jeremy, Barnett, Adrian, Roberts, Jason R. and Chan, Hak-Kim (2018). Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation. Pulmonary Pharmacology and Therapeutics, 50, 93-99. doi: 10.1016/j.pupt.2018.04.006

Characterisation of 40 mg/ml and 100 mg/ml tobramycin formulations for aerosol therapy with adult mechanical ventilation

2018

Conference Publication

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock

Obonyo, N., Byrne, L., Shiino, K., Diab, S., Dunster, K., Passmore, M., Boon, A.C., See Hoe, L., Pedersen, S., Fauzi, M., Pimenta, L., Van Haren, F., Shekar, K., Anstey, C., Tung, J.P., Cullen, L., Platts, D., Chan, J., Maitland, K. and Fraser, J. (2018). Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock. 9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies (WFPICCS 2018), Singapore, 9-13 June 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.pcc.0000538016.15507.8c

Fluid resuscitation with 0.9% saline impairs myocardial contractility in an ovine model of endotoxemic shock

2018

Journal Article

Cerebral microcirculation and histological mapping after severe head injury: a contusion and acceleration experimental model

Bellapart, Judith, Cuthbertson, Kylie, Dunster, Kimble, Diab, Sara, Platts, David G., Raffel, Owen Christopher, Gabrielian, Levon, Barnett, Adrian, Paratz, Jenifer, Boots, Rob and Fraser, John F. (2018). Cerebral microcirculation and histological mapping after severe head injury: a contusion and acceleration experimental model. Frontiers in Neurology, 9 (MAY) 277, 277. doi: 10.3389/fneur.2018.00277

Cerebral microcirculation and histological mapping after severe head injury: a contusion and acceleration experimental model

2018

Journal Article

Speed modulation of the heartWare HVAD to assess in vitro hemocompatibility of pulsatile and continuous flow regimes in a rotary blood pump

Horobin, Jarod T., Simmonds, Michael J., Nandakumar, Deepika, Gregory, Shaun D., Tansley, Geoff, Pauls, Jo P., Girnghuber, Angela, Balletti, Nicoletta and Fraser, John F. (2018). Speed modulation of the heartWare HVAD to assess in vitro hemocompatibility of pulsatile and continuous flow regimes in a rotary blood pump. Artificial Organs, 42 (9), 879-890. doi: 10.1111/aor.13142

Speed modulation of the heartWare HVAD to assess in vitro hemocompatibility of pulsatile and continuous flow regimes in a rotary blood pump

2018

Journal Article

Nursing challenges in interactions with patients receiving mechanical circulatory and respiratory support

Wrigley, Cara, Straker, Karla, Nusem, Erez, Fraser, John F. and Gregory, Shaun D. (2018). Nursing challenges in interactions with patients receiving mechanical circulatory and respiratory support. The Journal of Cardiovascular Nursing, 33 (5), 1-E15. doi: 10.1097/JCN.0000000000000494

Nursing challenges in interactions with patients receiving mechanical circulatory and respiratory support

2018

Journal Article

Comorbidities and ventricular dysfunction drive excess mid-term morbidity in an Indigenous Australian coronary revascularisation cohort

Wiemers, Paul D., Marney, Lucy, White, Nicole, Bough, Georgina, Hustig, Alistair, Tan, Wei, Cheng, Ching-Siang, Kang, Dong, Yadav, Sumit, Tam, Robert and Fraser, John F. (2018). Comorbidities and ventricular dysfunction drive excess mid-term morbidity in an Indigenous Australian coronary revascularisation cohort. Heart Lung and Circulation, 28 (6), 874-883. doi: 10.1016/j.hlc.2018.04.285

Comorbidities and ventricular dysfunction drive excess mid-term morbidity in an Indigenous Australian coronary revascularisation cohort

2018

Journal Article

Platelet storage lesions: what more do we know now?

Ng, Monica Suet Ying, Tung, John-Paul and Fraser, John Francis (2018). Platelet storage lesions: what more do we know now?. Transfusion Medicine Reviews, 32 (3), 144-154. doi: 10.1016/j.tmrv.2018.04.001

Platelet storage lesions: what more do we know now?

2018

Journal Article

Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance

Millar, Jonathan Edward, von Bahr, Viktor, Malfertheiner, Maximillian V., Ki, Katrina K., Redd, Meredith A., Bartnikowski, Nicole, Suen, Jacky Y., McAuley, Danny Francis and Fraser, John F. (2018). Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance. Thorax, 74 (2), 1-3. doi: 10.1136/thoraxjnl-2017-211439

Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance

2018

Journal Article

Untapped potential in Australian Hospitals for organ donation after circulatory death

See Hoe, Louise E., McGiffin, David and Fraser, John F. (2018). Untapped potential in Australian Hospitals for organ donation after circulatory death. Medical Journal of Australia, 208 (6), 276-277. doi: 10.5694/mja17.01052

Untapped potential in Australian Hospitals for organ donation after circulatory death

2018

Journal Article

Review article: Sepsis in the emergency department - Part 3: Treatment

Williams, Julian M., Keijzers, Gerben, Macdonald, Stephen Pj, Shetty, Amith and Fraser, John F (2018). Review article: Sepsis in the emergency department - Part 3: Treatment. EMA - Emergency Medicine Australasia, 30 (2), 144-151. doi: 10.1111/1742-6723.12951

Review article: Sepsis in the emergency department - Part 3: Treatment

2018

Journal Article

A randomized trial of high-flow oxygen therapy in infants with bronchiolitis

Franklin, Donna, Babl, Franz E, Schlapbach, Luregn J, Oakley, Ed, Craig, Simon, Neutze, Jocelyn, Furyk, Jeremy, Fraser, John F, Jones, Mark, Whitty, Jennifer A, Dalziel, Stuart R. and Schibler, Andreas (2018). A randomized trial of high-flow oxygen therapy in infants with bronchiolitis. New England Journal of Medicine, 378 (12), 1121-1131. doi: 10.1056/NEJMoa1714855

A randomized trial of high-flow oxygen therapy in infants with bronchiolitis

2018

Journal Article

Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction

Fanning, Jonathon P., See Hoe, Louise E., Passmore, Margaret R., Barnett, Adrian G., Rolfe, Barbara E., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky and Fraser, John F. (2018). Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction. Therapeutic Advances in Neurological Disorders, 11, 1756286418759493. doi: 10.1177/1756286418759493

Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction

2018

Journal Article

An overview of Indigenous Australian disadvantage in terms of ischaemic heart disease

Wiemers, Paul D., Marney, Lucy, Yadav, Sumit, Tam, Robert and Fraser, John F. (2018). An overview of Indigenous Australian disadvantage in terms of ischaemic heart disease. Heart, Lung and Circulation, 27 (11), 1274-1284. doi: 10.1016/j.hlc.2018.03.003

An overview of Indigenous Australian disadvantage in terms of ischaemic heart disease

2018

Journal Article

Extracorporeal membrane oxygenation line-associated complications: in vitro testing of cyanoacrylate tissue adhesive and securement devices to prevent infection and dislodgement

Bull, Taressa, Corley, Amanda, Smyth, Danielle J., McMillan, David J., Dunster, Kimble R. and Fraser, John F. (2018). Extracorporeal membrane oxygenation line-associated complications: in vitro testing of cyanoacrylate tissue adhesive and securement devices to prevent infection and dislodgement. Intensive Care Medicine Experimental, 6 (1) 6, 1-12. doi: 10.1186/s40635-018-0171-8

Extracorporeal membrane oxygenation line-associated complications: in vitro testing of cyanoacrylate tissue adhesive and securement devices to prevent infection and dislodgement

2018

Journal Article

Position paper for the organization of ECMO programs for cardiac failure in adults

Abrams, Darryl, Garan, A. Reshad, Abdelbary, Akram, Bacchetta, Matthew, Bartlett, Robert H., Beck, James, Belohlavek, Jan, Chen, Yih-Sharng, Fan, Eddy, Ferguson, Niall D., Fowles, Jo-anne, Fraser, John, Gong, Michelle, Hassan, Ibrahim F., Hodgson, Carol, Hou, Xiaotong, Hryniewicz, Katarzyna, Ichiba, Shingo, Jakobleff, William A., Lorusso, Roberto, MacLaren, Graeme, McGuinness, Shay, Mueller, Thomas, Park, Pauline K., Peek, Giles, Pellegrino, Vin, Price, Susanna, Rosenzweig, Erika B., Sakamoto, Tetsuya ... Brodie, Daniel (2018). Position paper for the organization of ECMO programs for cardiac failure in adults. Intensive Care Medicine, 44 (6), 1-13. doi: 10.1007/s00134-018-5064-5

Position paper for the organization of ECMO programs for cardiac failure in adults

2018

Journal Article

Review article: Sepsis in the emergency department - Part 2: Investigations and monitoring

Shetty, Amith, Macdonald, Stephen P. J., Keijzers, Gerben, Williams, Julian M., Tang, Benjamin, de Groot, Bas, Thompson, Kelly, Fraser, John F., Finfer, Simon, Bellomo, Rinaldo and Iredell, Jonathan (2018). Review article: Sepsis in the emergency department - Part 2: Investigations and monitoring. Emergency Medicine Australasia : EMA, 30 (1), 4-12. doi: 10.1111/1742-6723.12924

Review article: Sepsis in the emergency department - Part 2: Investigations and monitoring

2018

Journal Article

Time Course Response of the Heart and Circulatory System to Active Postural Changes

Pauls, Jo P., Roberts, Llion, Burgess, Tom, Fraser, John F., Gregory, Shaun D. and Tansley, Geoff (2018). Time Course Response of the Heart and Circulatory System to Active Postural Changes. Journal of Biomechanical Engineering, 140 (3) 034501, 1-4. doi: 10.1115/1.4038429

Time Course Response of the Heart and Circulatory System to Active Postural Changes

2018

Journal Article

An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma

Moosavi, Seyed Mojtaba, Shekar, Kiran, Fraser, John F., Smith, Maree T. and Ghassabian, Sussan (2018). An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 1073, 118-122. doi: 10.1016/j.jchromb.2017.12.006

An improved liquid chromatography tandem mass spectrometry (LC-MS/MS) method for quantification of dexmedetomidine concentrations in samples of human plasma

2018

Journal Article

Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia [version 2; referees: 2 approved]

Maitland, Kathryn, Kiguli, Sarah, Opoka, Robert O., Olupot-Olupot, Peter, Engoru, Charles, Njuguna, Patricia, Bandika, Victor, Mpoya, Ayub, Bush, Andrew, Williams, Thomas N., Grieve, Richard, Sadique, Zia, Fraser, John, Harrison, David and Rowan, Kathy (2018). Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia [version 2; referees: 2 approved]. Wellcome Open Research, 2 100, 1-36. doi: 10.12688/wellcomeopenres.12747.2

Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia [version 2; referees: 2 approved]

Current funding

  • 2025 - 2027
    REDEEM: A Randomised Controlled Trial of ECMO to Desedate, Extubate Early and Mobilise in severe acute respiratory infection (MRFF RCRDUN led by Monash University)
    Monash University
    Open grant
  • 2025 - 2027
    Load Incorporating Cardiac Assessment by Echocardiography to Refine Outcome Predictions In Patients with SEpsis: Prospective Multicentre Study (LIAISE study)
    TPCH Foundation Innovation Grants
    Open grant
  • 2025 - 2027
    Towards Equitable Monitoring in the ICU - Reducing Racial Bias of Pulse Oximeters with Corrective Algorithms
    TPCH Foundation Innovation Grants
    Open grant
  • 2024 - 2029
    Research Equipment for the Critical Care Research Group at IMB
    The Common Good and the Sheila & Bernard Joel Life Saving Medical Equipment Foundation
    Open grant
  • 2024 - 2028
    The HEART REHAB Clinical Trials: Therapeutics to Protect the Human Heart
    MRFF Frontier Health and Medical Research Program administered by AusIndustry
    Open grant
  • 2024 - 2026
    ALL IN - AI and Laboratory Led IdentificatioN of PASC
    NHMRC MRFF Post-Acute Sequelae of COVID-19
    Open grant
  • 2024 - 2026
    Addressing deficiencies of current ECMO with an innovative pulsatile flow technology (ADEPT)
    National Heart Foundation Vanguard Grant
    Open grant
  • 2023 - 2025
    Effect of mitochondrial transplantation following hypothermic machine perfusion on donor heart ischemic time
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2025
    Heart Ex Vivo Perfusion
    The Donald & Joan Wilson Foundation Ltd
    Open grant
  • 2023 - 2028
    Generating new evidence to reduce complications and improve the safety and efficacy of extracorporeal membrane oxygenation in patients with severe cardiac and respiratory failure (Ex led by Monash)
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant
  • 2020 - 2026
    Transfusion Triggers in Cardiac Surgery Australia trial (TRICS-IV) (MRFF ICTC Grant Led by University of Melbourne)
    University of Melbourne
    Open grant

Past funding

  • 2024
    The BLENDER Trial - Blend to Limit Oxygen in ECMO: A randomised Controlled Registry Trial (Monash University administered LCTRC grant)
    Monash University
    Open grant
  • 2024
    2023 Equipment grant - OxyLiteTM/OxyFloTM combined 4 Channel tissue pO2 and temperature monitor with touch screen
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2024
    A Comparative Assessment of the Distribution of Antibiotics in Pulsatile- and Continuous-Flow Venoarterial Extracorporeal Membrane Oxygenation: An Ovine Model of Severe Cardiogenic Shock
    Prince Charles Hospital Foundation
    Open grant
  • 2022 - 2024
    Developing FXIIa inhibitors as next-generation anticoagulants
    NHMRC Development Grant
    Open grant
  • 2021
    Equipment Grant - ULT (ultra low temperature) -80 degree freezer
    Prince Charles Hospital Foundation
    Open grant
  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2019 - 2022
    Nitric Oxide to improve recovery and survival in neonates and children on Extracorporeal Life Support - a pilot randomized controlled trial (the NECTAR trial)
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2021
    Novel fluid alternatives to blood transfusion to treat acute and chronic blood loss
    National Blood Authority
    Open grant
  • 2019
    Advanced Haemodynamic Monitoring for Large Animal Experimentation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2021
    The EXCEL Project: A collaborative approach to improve outcomes of Australian patients with acute heart failure and cardiac arrest requiring... (NHMRC Partnership Projects led by Monash University)
    Monash University
    Open grant
  • 2018 - 2022
    The Dead Heart Project: When is a 'dead' heart truly dead?
    NHMRC Project Grant
    Open grant
  • 2017 - 2020
    High flow nasal cannula treatment for infants and children with acute respiratory failure
    Thrasher Research Fund
    Open grant
  • 2017 - 2018
    The impact of extracorporeal membrane oxygenation (ECMO) on the activities of drug enzymes that affect the pharmacokinetics and therapeutic outcomes of clinically important drugs
    Prince Charles Hospital Foundation
    Open grant
  • 2016
    Assessment of cerebral microcirculation after severe head injury when exposed to acute anaemia
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016 - 2017
    Does inhaled tobramycin distribute effectively into the lungs? A comparative study using radiolabelled tobramycin.
    Royal Brisbane and Women's Hospital
    Open grant
  • 2016 - 2018
    Stemming devastating neurological injury caused by transcatheter aortic valve implantation (TAVI): First-in-man application of two novel neuroprotective strategies to an interventional cardiology...
    National Heart Foundation of Australia
    Open grant
  • 2015 - 2018
    Resuscitation in Endotoxaemic Shock - Understanding Sepsis (RESUS)
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Cerebral Microcirculation in Head Injury During Normovolemic Anemia: An Experimental Model
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015 - 2017
    High Flow Cannula Therapy in Bronchiolitis, a Randomised Controlled Trial
    NHMRC Project Grant
    Open grant
  • 2014 - 2021
    Centre for Research Excellence in Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS)
    NHMRC Centres of Research Excellence
    Open grant
  • 2014 - 2015
    Pilot study: High Flow Nasal Cannula (HFNC) therapy in infants with Bronchiolitis, a randomised controlled trial in regional emergency departments
    Queensland Emergency Medicine Research Foundation
    Open grant
  • 2014 - 2015
    Consequences of Bleeding on Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2014
    Assessment of the Cerebral Microcirculation after Head Injury
    DHF Establishment Grants
    Open grant
  • 2013 - 2015
    Assessment of the Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012
    Facilitating School of Medicine as a central coordinator of global pharmacokinetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    Investigation of the cerebral microcirculation after head injury : pilot study
    Brain Foundation
    Open grant
  • 2011 - 2013
    The unholy alliance between extracorporeal circuitry and the transfusion medicine: characterising inflammation and injury (NHMRC Project Grant led by The Prince Charles Hospital)
    Prince Charles Hospital
    Open grant
  • 2010 - 2011
    Novel Infusion Decision Support System for Circulatory Management of Intensive Care Patients
    UQ FirstLink Scheme
    Open grant
  • 2010 - 2011
    Novel Physiological Control of Bionic Hearts
    UQ FirstLink Scheme
    Open grant
  • 2009
    Improving outcomes post burn injury
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    Hyperpolarized helium MRI to quantify regional lung damage and ventilation for improvement of recruitment strategy
    NHMRC Project Grant
    Open grant
  • 2006 - 2012
    Endothelins in brain stem death - Effects on the right ventricle and Ischaemia repurfusion.
    Prince Charles Hospital Foundation
    Open grant
  • 2005 - 2007
    Studying factors from fetal sheep to test if they can reduce scarring in childhood burns
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2005
    Therapeutic strategies to prevent acute respiratory distress syndrome in patients with smoke inhalation. The effect of recombinant activated protein C (rhAPC) on acute lung injury....
    Royal Children's Hospital Foundation
    Open grant
  • 2001 - 2003
    Fetal wound healing: An ovine model for scarless burns recovery in children.
    Australian and New Zealand Burn Association Ltd
    Open grant
  • 2001 - 2002
    Fetal wound healing: An ovine model for scarless burns recovery in children
    Mayne Bequest Fund
    Open grant
  • 2001 - 2003
    CONROD - RACS TRAUMA FELLOWSHIP: Therapeutic strategies to prevent ARDS in patients with smoke inhalation.
    Royal Australasian College of Surgeons
    Open grant

Availability

Professor John Fraser is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Development of Speckle-Tracking Echocardiographic strain accounting for cardiac loading conditions

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Vascular Endothelial Injury, Repair and Preconditioning in the Artificial Circulation

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    ICU of the Future

    Principal Advisor

    Other advisors: Associate Professor Allison Mandrusiak

  • Doctor Philosophy

    Fibrinogen Replacement in Traumatic Haemorrhage

    Principal Advisor

  • Doctor Philosophy

    Vascular Endothelial Injury, Repair and Preconditioning in the Artificial Circulation

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Load-Independent Right Ventricular Assessment by Echocardiography

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Development of a novel pulmonary imaging technology for mechanically ventilated patients.

    Principal Advisor

    Other advisors: Dr Gianluigi Li Bassi

  • Doctor Philosophy

    The ICU of the future project ¿ can redesigning the ICU environment improve patient outcomes?

    Principal Advisor

    Other advisors: Associate Professor Allison Mandrusiak

  • Doctor Philosophy

    Novel Right Heart Assessment by Speckle Tracking Echocardiography

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Examining healthcare access and outcomes for Aboriginal and Torres Strait Islander people with rheumatic heart disease in Queensland.

    Associate Advisor

Completed supervision

Enquiries

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