Professor John Fraser
Professor

John Fraser

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Availability

Professor John Fraser is:
Available for supervision

Search Professor John Fraser’s works on UQ eSpace

758 works between 2000 and 2025
All (758) Book (1) Journal Article (612) Other Outputs (2) Edited Outputs (3) Conference Publication (132) Book Chapter (8)

341 - 360 of 758 works

2018

Book Chapter

Clinical implications of monitoring tissue perfusion in cardiogenic shock

Moore, John and Fraser, John F. (2018). Clinical implications of monitoring tissue perfusion in cardiogenic shock. Monitoring tissue perfusion in shock: from physiology to the bedside. (pp. 193-206) edited by Alexandre Augusto Pinto Lima and Eliézer Silva. Cham, Switzerland: Springer. doi: 10.1007/978-3-319-43130-7_14

Clinical implications of monitoring tissue perfusion in cardiogenic shock

2018

Conference Publication

Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI

Fanning, Jonathon P., Hoe, See Louise E., Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Suen, Jacky Y. and Fraser, John F. (2018). Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI

2018

Conference Publication

Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research

Bartnikowski, N., Obonyo, N., Pedersen, S., Wells, M., Millar, J., Raffel, O., Suen, J., Gregory, S., Haqqani, H. and Fraser, J. (2018). Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, QLD Australia, 2 - 5 August 2018. Chatswood, NSW Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.110

Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research

2018

Journal Article

Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia [version 2; referees: 2 approved]

Maitland, Kathryn, Kiguli, Sarah, Opoka, Robert O., Olupot-Olupot, Peter, Engoru, Charles, Njuguna, Patricia, Bandika, Victor, Mpoya, Ayub, Bush, Andrew, Williams, Thomas N., Grieve, Richard, Sadique, Zia, Fraser, John, Harrison, David and Rowan, Kathy (2018). Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia [version 2; referees: 2 approved]. Wellcome Open Research, 2 100, 1-36. doi: 10.12688/wellcomeopenres.12747.2

Children's Oxygen Administration Strategies Trial (COAST): A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia [version 2; referees: 2 approved]

2018

Conference Publication

Explant of heartware biventricular assist devices following myocardial recovery after peripartum cardiomyopathy

Lau, K., Bancroft, J., McKenzie, S., Javorsky, G., Chan, W., Wong, Y., Thomson, B., Prabhu, A., Fraser, J. and Platts, D. (2018). Explant of heartware biventricular assist devices following myocardial recovery after peripartum cardiomyopathy. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, QLD Australia, 2-5 August 2018. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2018.06.126

Explant of heartware biventricular assist devices following myocardial recovery after peripartum cardiomyopathy

2018

Conference Publication

Development of an ovine model of heart transplantation following 24-hour brain stem death

See Hoe, L., Engkilde-Pedersen, S., Obonyo, N., Wells, M., Boon, C., Bartnikowski, N., Passmore, M., McDonald, C., Black, D., Molenaar, P., Diab, S., Suen, J., Marasco, S., McGiffin, D. and Fraser, J. (2018). Development of an ovine model of heart transplantation following 24-hour brain stem death. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.111

Development of an ovine model of heart transplantation following 24-hour brain stem death

2017

Journal Article

Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy

Adiraju, Santosh Kumar Sreevatsav, Shekar, Kiran, Fraser, John F, Smith, Maree T and Ghassabian, Sussan (2017). Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy. Drug metabolism reviews, 50 (2), 1-16. doi: 10.1080/03602532.2017.1417423

Effect of cardiopulmonary bypass on cytochrome P450 enzyme activity: implications for pharmacotherapy

2017

Journal Article

Topographical distribution of perioperative cerebral infarction associated with transcatheter aortic valve implantation

Fanning, Jonathon P., Wesley, Allan J., Walters, Darren L., Wong, Andrew A., Barnett, Adrian G., Strugnell, Wendy E., Platts, David G. and Fraser, John F. (2017). Topographical distribution of perioperative cerebral infarction associated with transcatheter aortic valve implantation. American Heart Journal, 197, 113-123. doi: 10.1016/j.ahj.2017.12.008

Topographical distribution of perioperative cerebral infarction associated with transcatheter aortic valve implantation

2017

Journal Article

Nano- and Micro-materials in the Treatment of Internal Bleeding and Uncontrolled Haemorrhage

Gaston, Elizabeth, Fraser, John F, Xu, Zhi Ping and Ta, Hang T (2017). Nano- and Micro-materials in the Treatment of Internal Bleeding and Uncontrolled Haemorrhage. Nanomedicine : nanotechnology, biology, and medicine, 14 (2), 507-519. doi: 10.1016/j.nano.2017.11.007

Nano- and Micro-materials in the Treatment of Internal Bleeding and Uncontrolled Haemorrhage

2017

Journal Article

Thermal clothing to reduce heart failure morbidity during winter: a randomised controlled trial

Barnett, Adrian Gerard, Stewart, Ian, Beevers, Andrea, Fraser, John F. and Platts, David (2017). Thermal clothing to reduce heart failure morbidity during winter: a randomised controlled trial. BMJ Open, 7 (10) e017592, 1-8. doi: 10.1136/bmjopen-2017-017592

Thermal clothing to reduce heart failure morbidity during winter: a randomised controlled trial

2017

Journal Article

Appraising extracorporeal life support — current and future roles in adult intensive care

Shekar, Kiran, Brodie, Daniel, Fraser, John and MacLaren, Graeme (2017). Appraising extracorporeal life support — current and future roles in adult intensive care. Critical Care and Resuscitation, 19, 5-7.

Appraising extracorporeal life support — current and future roles in adult intensive care

2017

Journal Article

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

Sinnah, Fabrice, Shekar, Kiran, Abdul-Aziz, Mohd H, Buscher, Hergen, Diab, Sara D., Fisquet, Stephanie, Fung, Yoke L., McDonald, Charles I., Reynolds, Claire, Rudham, Sam, Wallis, Steven C., Welch, Susan, Xie, Jiao, Fraser, John F., Roberts, Jason A. and ASAP ECMO investigators (2017). Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation. Critical Care and Resuscitation, 19 (Suppl 1), 8-14.

Incremental research approach to describing the pharmacokinetics of ciprofloxacin during extracorporeal membrane oxygenation

2017

Journal Article

Rise of the machines - the growing influence of the Asia-Pacific in the world of mechanical support

Fraser, John F and Bellomo, Rinaldo (2017). Rise of the machines - the growing influence of the Asia-Pacific in the world of mechanical support. Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine, 19 (Suppl 1), 3-4.

Rise of the machines - the growing influence of the Asia-Pacific in the world of mechanical support

2017

Journal Article

Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature

Malfertheiner, M. V., Pimenta, L. P., Von Bahr, V., Millar, J. E., Obonyo, N. G., Suen, J. Y., Pellegrino, V. and Fraser, J. F. (2017). Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature. Critical Care and Resuscitation, 19, 45-52.

Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature

2017

Journal Article

The effect of compliant inflow cannulae on the hemocompatibility of rotary blood pump circuits in an in vitro model

Pauls, Jo P., Nandakumar, Deepika, Horobin, Jarod, Prendeville, Justin D., Simmonds, Michael J., Fraser, John F., Tansley, Geoff and Gregory, Shaun D. (2017). The effect of compliant inflow cannulae on the hemocompatibility of rotary blood pump circuits in an in vitro model. Artificial Organs, 41 (10), E118-E128. doi: 10.1111/aor.12919

The effect of compliant inflow cannulae on the hemocompatibility of rotary blood pump circuits in an in vitro model

2017

Journal Article

To be or not to be on ECMO: can survival prediction models solve the question?

Rozencwajg, Sacha, Fraser, John, Montero, Santiago, Combes, Alain and Schmidt, Matthieu (2017). To be or not to be on ECMO: can survival prediction models solve the question?. Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine, 19 (Suppl 1), 21-28.

To be or not to be on ECMO: can survival prediction models solve the question?

2017

Journal Article

Intraoperative Cerebral Perfusion Disturbances During Transcatheter Aortic Valve Replacement

Fanning, Jonathon P., Walters, Darren L., Wesley, Allan J., Anstey, Chris, Huth, Samuel, Bellapart, Judith, Collard, Caroline, Rapchuk, Ivan L., Natani, Sarvesh, Savage, Michael and Fraser, John F. (2017). Intraoperative Cerebral Perfusion Disturbances During Transcatheter Aortic Valve Replacement. Annals of Thoracic Surgery, 104 (5), 1564-1568. doi: 10.1016/j.athoracsur.2017.04.053

Intraoperative Cerebral Perfusion Disturbances During Transcatheter Aortic Valve Replacement

2017

Journal Article

Contrast microsphere destruction by a continuous flow ventricular assist device: an in vitro evaluation using a mock circulation loop

Platts, David G., Bartnikowski, Nicole, Gregory, Shaun D., Scalia, Gregory M. and Fraser, John F. (2017). Contrast microsphere destruction by a continuous flow ventricular assist device: an in vitro evaluation using a mock circulation loop. BioMed Research International, 2017 4907898, 4907898-9. doi: 10.1155/2017/4907898

Contrast microsphere destruction by a continuous flow ventricular assist device: an in vitro evaluation using a mock circulation loop

2017

Journal Article

Ventilation distribution and lung recruitment with speaking valve use in tracheostomised patient weaning from mechanical ventilation in intensive care

Sutt, Anna-Liisa, Anstey, Chris M., Caruana, Lawrence R., Cornwell, Petrea L. and Fraser, John F. (2017). Ventilation distribution and lung recruitment with speaking valve use in tracheostomised patient weaning from mechanical ventilation in intensive care. Journal of Critical Care, 40, 164-170. doi: 10.1016/j.jcrc.2017.04.001

Ventilation distribution and lung recruitment with speaking valve use in tracheostomised patient weaning from mechanical ventilation in intensive care

2017

Journal Article

REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): Study protocol for a pilot randomised controlled trial

Macdonald, Stephen P. J., Taylor, David Mcd, Keijzers, Gerben, Arendts, Glenn, Fatovich, Daniel M., Kinnear, Frances B., Brown, Simon G. A., Bellomo, Rinaldo, Burrows, Sally, Fraser, John F., Litton, Edward, Ascencio-Lane, Juan Carlos, Anstey, Matthew, McCutcheon, David, Smart, Lisa, Vlad, Ioana, Winearls, James and Wibrow, Bradley (2017). REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): Study protocol for a pilot randomised controlled trial. Trials, 18 (1) 399, 399. doi: 10.1186/s13063-017-2137-7

REstricted Fluid REsuscitation in Sepsis-associated Hypotension (REFRESH): Study protocol for a pilot randomised controlled trial

Current funding

  • 2026 - 2027
    PuMPS Vanguard Pilot: a randomised trial of pulsatile versus continuous flow cardiopulmonary bypass in high-risk cardiac surgery
    National Heart Foundation Vanguard Grant
    Open grant
  • 2025 - 2026
    PRIMELab Research Fellowship
    Prince Charles Hospital Foundation
    Open grant
  • 2025 - 2027
    REDEEM: A Randomised Controlled Trial of ECMO to Desedate, Extubate Early and Mobilise in severe acute respiratory infection (MRFF RCRDUN led by Monash University)
    Monash University
    Open grant
  • 2025 - 2027
    Load Incorporating Cardiac Assessment by Echocardiography to Refine Outcome Predictions In Patients with SEpsis: Prospective Multicentre Study (LIAISE study)
    TPCH Foundation Innovation Grants
    Open grant
  • 2025 - 2027
    Towards Equitable Monitoring in the ICU - Reducing Racial Bias of Pulse Oximeters with Corrective Algorithms
    TPCH Foundation Innovation Grants
    Open grant
  • 2024 - 2029
    Research Equipment for the Critical Care Research Group at IMB
    The Common Good and the Sheila & Bernard Joel Life Saving Medical Equipment Foundation
    Open grant
  • 2024 - 2028
    The HEART REHAB Clinical Trials: Therapeutics to Protect the Human Heart
    MRFF Frontier Health and Medical Research Program administered by AusIndustry
    Open grant
  • 2024 - 2026
    ALL IN - AI and Laboratory Led IdentificatioN of PASC
    NHMRC MRFF Post-Acute Sequelae of COVID-19
    Open grant
  • 2024 - 2026
    Addressing deficiencies of current ECMO with an innovative pulsatile flow technology (ADEPT)
    National Heart Foundation Vanguard Grant
    Open grant
  • 2023 - 2027
    Effect of mitochondrial transplantation following hypothermic machine perfusion on donor heart ischemic time
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2027
    Heart Ex Vivo Perfusion
    The Donald & Joan Wilson Foundation Ltd
    Open grant
  • 2023 - 2028
    Generating new evidence to reduce complications and improve the safety and efficacy of extracorporeal membrane oxygenation in patients with severe cardiac and respiratory failure (MRFF grant led by Mo
    Monash University
    Open grant
  • 2022 - 2026
    PRecision Ecmo in CardIogenic Shock Evaluation: PRECISE Study (MRFF grant administered by Monash University)
    Monash University
    Open grant
  • 2020 - 2027
    Transfusion Triggers in Cardiac Surgery Australia trial (TRICS-IV) (MRFF ICTC Grant Led by University of Melbourne)
    University of Melbourne
    Open grant

Past funding

  • 2024
    The BLENDER Trial - Blend to Limit Oxygen in ECMO: A randomised Controlled Registry Trial (Monash University administered LCTRC grant)
    Monash University
    Open grant
  • 2024
    2023 Equipment grant - OxyLiteTM/OxyFloTM combined 4 Channel tissue pO2 and temperature monitor with touch screen
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2024
    A Comparative Assessment of the Distribution of Antibiotics in Pulsatile- and Continuous-Flow Venoarterial Extracorporeal Membrane Oxygenation: An Ovine Model of Severe Cardiogenic Shock
    Prince Charles Hospital Foundation
    Open grant
  • 2022 - 2024
    Developing FXIIa inhibitors as next-generation anticoagulants
    NHMRC Development Grant
    Open grant
  • 2021
    Equipment Grant - ULT (ultra low temperature) -80 degree freezer
    Prince Charles Hospital Foundation
    Open grant
  • 2021 - 2024
    Development of a first-in-class therapeutic for protecting the ischemic heart
    NHMRC Development Grant
    Open grant
  • 2019 - 2022
    Nitric Oxide to improve recovery and survival in neonates and children on Extracorporeal Life Support - a pilot randomized controlled trial (the NECTAR trial)
    The Children's Hospital Foundation
    Open grant
  • 2019 - 2021
    Novel fluid alternatives to blood transfusion to treat acute and chronic blood loss
    National Blood Authority
    Open grant
  • 2019
    Advanced Haemodynamic Monitoring for Large Animal Experimentation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2021
    The EXCEL Project: A collaborative approach to improve outcomes of Australian patients with acute heart failure and cardiac arrest requiring... (NHMRC Partnership Projects led by Monash University)
    Monash University
    Open grant
  • 2018 - 2022
    The Dead Heart Project: When is a 'dead' heart truly dead?
    NHMRC Project Grant
    Open grant
  • 2017 - 2020
    High flow nasal cannula treatment for infants and children with acute respiratory failure
    Thrasher Research Fund
    Open grant
  • 2017 - 2018
    The impact of extracorporeal membrane oxygenation (ECMO) on the activities of drug enzymes that affect the pharmacokinetics and therapeutic outcomes of clinically important drugs
    Prince Charles Hospital Foundation
    Open grant
  • 2016
    Assessment of cerebral microcirculation after severe head injury when exposed to acute anaemia
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016 - 2017
    Does inhaled tobramycin distribute effectively into the lungs? A comparative study using radiolabelled tobramycin.
    Royal Brisbane and Women's Hospital
    Open grant
  • 2016 - 2018
    Stemming devastating neurological injury caused by transcatheter aortic valve implantation (TAVI): First-in-man application of two novel neuroprotective strategies to an interventional cardiology...
    National Heart Foundation of Australia
    Open grant
  • 2015 - 2018
    Resuscitation in Endotoxaemic Shock - Understanding Sepsis (RESUS)
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    Cerebral Microcirculation in Head Injury During Normovolemic Anemia: An Experimental Model
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015 - 2017
    High Flow Cannula Therapy in Bronchiolitis, a Randomised Controlled Trial
    NHMRC Project Grant
    Open grant
  • 2014 - 2021
    Centre for Research Excellence in Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS)
    NHMRC Centres of Research Excellence
    Open grant
  • 2014 - 2015
    Pilot study: High Flow Nasal Cannula (HFNC) therapy in infants with Bronchiolitis, a randomised controlled trial in regional emergency departments
    Queensland Emergency Medicine Research Foundation
    Open grant
  • 2014 - 2015
    Consequences of Bleeding on Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2014
    Imaging the Microcirculation in Critical Care Research
    NHMRC Equipment Grant
    Open grant
  • 2013 - 2014
    Assessment of the Cerebral Microcirculation after Head Injury
    DHF Establishment Grants
    Open grant
  • 2013 - 2015
    Assessment of the Cerebral Microcirculation after Head Injury
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012
    Facilitating School of Medicine as a central coordinator of global pharmacokinetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011 - 2013
    Investigation of the cerebral microcirculation after head injury : pilot study
    Brain Foundation
    Open grant
  • 2011 - 2013
    The unholy alliance between extracorporeal circuitry and the transfusion medicine: characterising inflammation and injury (NHMRC Project Grant led by The Prince Charles Hospital)
    Prince Charles Hospital
    Open grant
  • 2010 - 2011
    Novel Infusion Decision Support System for Circulatory Management of Intensive Care Patients
    UQ FirstLink Scheme
    Open grant
  • 2010 - 2011
    Novel Physiological Control of Bionic Hearts
    UQ FirstLink Scheme
    Open grant
  • 2009
    Improving outcomes post burn injury
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    Hyperpolarized helium MRI to quantify regional lung damage and ventilation for improvement of recruitment strategy
    NHMRC Project Grant
    Open grant
  • 2006 - 2012
    Endothelins in brain stem death - Effects on the right ventricle and Ischaemia repurfusion.
    Prince Charles Hospital Foundation
    Open grant
  • 2005 - 2007
    Studying factors from fetal sheep to test if they can reduce scarring in childhood burns
    Royal Children's Hospital Foundation
    Open grant
  • 2004 - 2005
    Therapeutic strategies to prevent acute respiratory distress syndrome in patients with smoke inhalation. The effect of recombinant activated protein C (rhAPC) on acute lung injury....
    Royal Children's Hospital Foundation
    Open grant
  • 2001 - 2003
    Fetal wound healing: An ovine model for scarless burns recovery in children.
    Australian and New Zealand Burn Association Ltd
    Open grant
  • 2001 - 2002
    Fetal wound healing: An ovine model for scarless burns recovery in children
    Mayne Bequest Fund
    Open grant
  • 2001 - 2003
    CONROD - RACS TRAUMA FELLOWSHIP: Therapeutic strategies to prevent ARDS in patients with smoke inhalation.
    Royal Australasian College of Surgeons
    Open grant

Availability

Professor John Fraser is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Development of a novel pulmonary imaging technology for mechanically ventilated patients.

    Principal Advisor

    Other advisors: Dr Gianluigi Li Bassi

  • Doctor Philosophy

    The importance of blood flow pattern on ECMO and cardiogenic shock

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Fibrinogen Replacement in Traumatic Haemorrhage

    Principal Advisor

  • Doctor Philosophy

    Vascular Endothelial Injury, Repair and Preconditioning in the Artificial Circulation

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Load-Independent Right Ventricular Assessment by Echocardiography

    Principal Advisor

    Other advisors: Dr Jacky Suen

  • Doctor Philosophy

    Ending rheumatic heart disease in Queensland: Epidemiological insights towards equity and place-based solutions

    Associate Advisor

  • Doctor Philosophy

    An investigation of Veno-Arterial Extracorporeal Membrane Oxygenation (V-A ECMO) and its interaction with Continuous Renal Replacement Therapy (CRRT)

    Associate Advisor

    Other advisors: Dr Jacky Suen

Completed supervision

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