
Overview
Background
Jeff Coombes is a Professor in the School of Human Movement Studies. He completed undergraduate degrees in applied science and education and a research Masters at the University of Tasmania before gaining a PhD from the University of Florida. After completing his PhD he returned to Australia to spend two years in an academic position at the University of Tasmania before moving to the University of Queensland in 2000.
Jeff's research interests focus on determining the optimal exercise prescription for improving health. With theoretical backgrounds in biochemistry and physiology he conducts human studies and basic science projects. His findings have emphasised the importance of cardiorespiratory fitness for health benefits and many of his current projects are using high intensity interval to improve fitness and investigate outcomes. The basic science projects are identifying the mechanisms that explain the health benefits of exercise and include work in the cardiovascular and musculoskeletal systems at cellular and molecular levels. He is also a passionate advocate on the importance of fitness for health and delivers many presentations to impact on public health. His research group comprises doctors, postdoctoral fellows and PhD students and uses the extensive resources of the exercise physiology and exercise biochemistry laboratories in the School of Human Movement and Nutrition Sciences.
Current research projects of the group include;
- High intensity interval training in patients with chronic kidney disease
- High intensity interval training in patients with metabolic syndrome
- High intensity interval training in overweight and obese children and adolescents
- Cardiorespiratory fitness and outcome in patients receiving a liver transplant
- Multi-disciplinary lifestyle intervention in patients with chronic kidney disease
- Exercise training in patients with diabetic cardiac autonomic neuropathy
- Oxidative stress and antioxidant biomarkers to predict the cardiorespiratory fitness response to exercise
- Molecular mechanisms of exercise cardioprotection: relations with oxidative stress
- Activation of NRF2 by nutritional supplementation in patients with type 2 diabetes
- Exercise-training and skeletal muscle O-glycnacylation
- Antioxidant supplementation in health and disease
Availability
- Professor Jeff Coombes is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Exercise is Medicine
Works
Search Professor Jeff Coombes’s works on UQ eSpace
2014
Conference Publication
Association Between Serum Alkaline Phosphatase and Resistance to Erythropoiesis Stimulating Agents in Chronic Kidney Disease: a Post-Hoc Analysis of the Hero Trial
Badve, S. V., Pascoe, E. M., Cass, A., Clarke, P., Coombes, J., Ferrari, P., Mcdonald, S. P., Morrish, A. T., Pedagogos, E., Perkovic, V., Reidlinger, D., Scaria, A., Walker, R., Vergara, L. A., Hawley, C. M. and Johnson, D. W. (2014). Association Between Serum Alkaline Phosphatase and Resistance to Erythropoiesis Stimulating Agents in Chronic Kidney Disease: a Post-Hoc Analysis of the Hero Trial. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourme, VIC Australia, 25-27 August 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301
2013
Journal Article
Protein-bound uremic toxins, inflammation and oxidative stress: A cross-sectional study in stage 3-4 chronic kidney disease
Rossi, M., Campbell, K.L., Johnson, D.W., Stanton, T., Vesey, D.A., Coombes, J.S., Weston, K.S., Hawley, C.M., McWhinney, B.C., Ungerer, J.P.J. and Isbel, N. (2013). Protein-bound uremic toxins, inflammation and oxidative stress: A cross-sectional study in stage 3-4 chronic kidney disease. Archives of Medical Research, 45 (4), 309-317. doi: 10.1016/j.arcmed.2014.04.002
2013
Journal Article
Sulforaphane: translational research from laboratory bench to clinic
Houghton, Christine A., Fassett, Robert G. and Coombes, Jeff S. (2013). Sulforaphane: translational research from laboratory bench to clinic. Nutrition Reviews, 71 (11), 709-726. doi: 10.1111/nure.12060
2013
Journal Article
High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis
Weston, Kassia S., Wisløff, Ulrik and Coombes, Jeff S. (2013). High-intensity interval training in patients with lifestyle-induced cardiometabolic disease: a systematic review and meta-analysis. British Journal of Sports Medicine, 48 (16), 1227-1234. doi: 10.1136/bjsports-2013-092576
2013
Journal Article
A pilot study: bovine colostrum supplementation and hormonal and autonomic responses to competitive cycling
Shing, C. M., Peake, J. M., Suzuki, K., Jenkins, D. G. and Coombes, J. S. (2013). A pilot study: bovine colostrum supplementation and hormonal and autonomic responses to competitive cycling. The Journal of Sports Medicine and Physical Fitness, 53 (5), 490-501.
2013
Journal Article
Exercise & Sports Science Australia (ESSA) position statement on exercise and chronic kidney disease
Smart, Neil A., Williams, Andrew D., Levinger, Itamar, Selig, Steve, Howden, Erin, Coombes, Jeff S. and Fassett, Robert G. (2013). Exercise & Sports Science Australia (ESSA) position statement on exercise and chronic kidney disease. Journal of Science and Medicine in Sport, 16 (5), 406-411. doi: 10.1016/j.jsams.2013.01.005
2013
Journal Article
Effects of Exercise and Lifestyle Intervention on Cardiovascular Function in CKD
Howden, Erin J., Leano, Rodel, Petchey, William, Coombes, Jeff S., Isbel, Nicole M. and Marwick, Thomas H. (2013). Effects of Exercise and Lifestyle Intervention on Cardiovascular Function in CKD. Clinical Journal of the American Society of Nephrology, 8 (9), 1494-1501. doi: 10.2215/CJN.10141012
2013
Journal Article
Factors influencing serum caffeine concentrations following caffeine ingestion
Skinner, Tina L., Jenkins, David G., Leveritt, Michael D., McGorm, Alastair, Bolam, Kate A., Coombes, Jeff S. and Taaffe, Dennis R. (2013). Factors influencing serum caffeine concentrations following caffeine ingestion. Journal of Science and Medicine in Sport, 17 (5), 516-520. doi: 10.1016/j.jsams.2013.07.006
2013
Journal Article
Reply to Morton. Heart-rate responses to exercise in patients with diabetes with acute or chronic autonomic dysfunction
Sacre, J. W., Jellis, C. L., Coombes, J. S. and Marwick, T. H. (2013). Reply to Morton. Heart-rate responses to exercise in patients with diabetes with acute or chronic autonomic dysfunction. Diabetic Medicine, 30 (8), 1010-1011. doi: 10.1111/dme.12178
2013
Journal Article
Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE−/− mice
Matsumoto, Aya, Manthey, Helga D., Marsh, Susan A., Fassett, Robert G., de Haan, Judy B., Rolfe, Barbara E. and Coombes, Jeff S. (2013). Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE−/− mice. International Journal of Cardiology, 167 (4), 1282-1288. doi: 10.1016/j.ijcard.2012.03.172
2013
Journal Article
Variability in oxidative stress biomarkers following a maximal exercise test
Mullins, Anna L., van Rosendal, Simon P., Briskey, David R., Fassett, Robert G., Wilson, Gary R. and Coombes, Jeff S. (2013). Variability in oxidative stress biomarkers following a maximal exercise test. Biomarkers, 18 (5), 446-454. doi: 10.3109/1354750X.2013.810668
2013
Journal Article
Influence of carbohydrate on serum caffeine concentrations following caffeine ingestion
Skinner, Tina L., Jenkins, David G., Folling, Jennifer, Leveritt, Michael D., Coombes, Jeff S. and Taaffe, Dennis R. (2013). Influence of carbohydrate on serum caffeine concentrations following caffeine ingestion. Journal of Science and Medicine in Sport, 16 (4), 343-347. doi: 10.1016/j.jsams.2012.08.004
2013
Journal Article
Statins in acute kidney injury: friend or foe?
Fassett, Robert G. and Coombes, Jeff S. (2013). Statins in acute kidney injury: friend or foe?. BMJ, 346 (7900), f1531.1-f1531.2. doi: 10.1136/bmj.f1531
2013
Journal Article
QT interval variability in Type 2 diabetic patients with cardiac sympathetic dysinnervation assessed by (123) I-Metaiodobenzylguanidine scintigraphy
Sacre, Julian W., Franjic, Bennett, Coombes, Jeff S., Marwick, Thomas H. and Baumert, Mathias (2013). QT interval variability in Type 2 diabetic patients with cardiac sympathetic dysinnervation assessed by (123) I-Metaiodobenzylguanidine scintigraphy. Journal of Cardiovascular Electrophysiology, 24 (3), 305-313. doi: 10.1111/jce.12039
2013
Journal Article
Response to 'More fuel in the obesity paradox debate': fatness, fitness, stiffness and blood pressure
Sharman, J. E., Stowasser, M., Kolade, O. O., Coombes, J. S., Fassett, R. G. and Marwick, T. H. (2013). Response to 'More fuel in the obesity paradox debate': fatness, fitness, stiffness and blood pressure. International Journal of Obesity, 37 (2), 320-321. doi: 10.1038/ijo.2012.44
2013
Conference Publication
Exercise and lifestyle intervention in chronic kidney disease: effects on cardiovascular function
Isbel, N., Howden, E., Leano, R., Petchey, W. and Coombes, J. (2013). Exercise and lifestyle intervention in chronic kidney disease: effects on cardiovascular function. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD, Australia, 9-11 September 2013. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.12121
2013
Conference Publication
Altered cardiac structure, diastolic function and markers of cardiovascular risk (inflammation, oxidative stress and endothelial dysfunction) in adolescents with type 1 diabetes
Conwell, Louise S., Baskerville, Tracey, Duncan, Danusia, Greer, Ristan M., Coombes, Jeff S., Leong, Gary M., Harris, Mark and Kostner, Karam (2013). Altered cardiac structure, diastolic function and markers of cardiovascular risk (inflammation, oxidative stress and endothelial dysfunction) in adolescents with type 1 diabetes. APEG 2013: Australasian Paediatric Endocrine Group Annual Scientific Meeting, Sydney, NSW, Australia, 28-31 July, 2013.
2013
Conference Publication
Investigating the clinical effect of resveratrol in non-alcoholic fatty liver disease: a randomised, double blind, placebo-controlled trial
Chachay, V. S., Martin, J. H., Prins, J. B., Whitehead, J. P., O'Moore-Sullivan, T. M., Lee, P., Franklin, M., Klein, K., Taylor, P. J., Ferguson, M., Coombes, J. S., Thomas, G. P., Cowin, G. J., Kirkpatrick, C. M. J., Macdonald, G. A. and Hickman, I. J. (2013). Investigating the clinical effect of resveratrol in non-alcoholic fatty liver disease: a randomised, double blind, placebo-controlled trial. Australian Gastroenterology Week 2013, Melbourne, VIC, Australia, 7-9 October 2013. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/jgh.12365_5
2013
Conference Publication
Oxidative stress is associated with poor grip strength and sarcopenia in patients with chronic kidney disease
Weston, K., Howden, E., Briskey, D., Isbel, N. and Coombes, J. (2013). Oxidative stress is associated with poor grip strength and sarcopenia in patients with chronic kidney disease. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD, Australia, 9-11 September 2013. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.12121
2013
Conference Publication
Peroxisome proliferator activated receptor-y activation does not protect human kidney proximal tubular epithelial cells against oxidative stress
Small, D., Morais, C., Johnson, D., Coombes, J. and Gobe, G. (2013). Peroxisome proliferator activated receptor-y activation does not protect human kidney proximal tubular epithelial cells against oxidative stress. 49th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Brisbane, QLD Australia, 9-11 September 2013. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12121
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jeff Coombes is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Exercise Training and Body Composition in Children and Adolescents with Congenital Heart Disease
Principal Advisor
Other advisors: Dr Shelley Keating
-
Doctor Philosophy
Exercise and Anti-Obesity Medications
Principal Advisor
Other advisors: Dr Riley Brown, Dr Shelley Keating
-
Doctor Philosophy
Exercise Training and Body Composition in Children and Adolescents with Congenital Heart Disease
Principal Advisor
Other advisors: Dr Shelley Keating
-
Doctor Philosophy
Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.
Principal Advisor
Other advisors: Professor Gerald Holtmann
-
Doctor Philosophy
Exercise Training in People with Mild Cognitive Impairment
Principal Advisor
Other advisors: Dr Shelley Keating
-
Doctor Philosophy
Exercise Training in People with Mild Cognitive Impairment
Principal Advisor
Other advisors: Dr Shelley Keating
-
Master Philosophy
Structured exercise program to reduce fatigue in patients receiving dialysis: an adaptive trial (M-FIT)
Principal Advisor
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Doctor Philosophy
The Design, Establishment and Effectiveness of a Rehabilitation Pathway for Individuals with Postural Orthostatic Tachycardia Syndrome (POTS)
Associate Advisor
Other advisors: Dr Jenna Taylor
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Master Philosophy
Assessment of muscle mass hepatic function and outcomes in patients awaiting liver transplantation
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
-
Doctor Philosophy
Exercise training for cerebrovascular health in perimenopausal women
Associate Advisor
Other advisors: Dr Jenna Taylor
Completed supervision
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2022
Doctor Philosophy
Comparison of Low-Volume, High-Intensity Aerobic and Resistance Interval Training with Current Exercise Recommendations on Cardiometabolic Outcomes in People with Type 2 Diabetes
Principal Advisor
Other advisors: Emeritus Professor Wendy Brown, Dr Shelley Keating
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2022
Doctor Philosophy
Effects of Fitness and Exercise Training on Vascular Function in older adults with Mild Cognitive Impairment: Role of Age and Sex
Principal Advisor
Other advisors: Dr Tom Bailey
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2021
Doctor Philosophy
Predicting and improving aerobic exercise training response
Principal Advisor
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2021
Doctor Philosophy
The Effects of Exercise on Early Markers of Cardiovascular Disease Risk in Those Living with and Beyond Cancer
Principal Advisor
Other advisors: Dr Tom Bailey
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2020
Doctor Philosophy
The physiological, morphological and functional responses to resistance exercise with blood flow restriction: An examination of protocol type and exercise load
Principal Advisor
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2020
Doctor Philosophy
The Physiological, Biochemical and Psychological Effects of Low-Volume Combined Aerobic and Resistance High-Intensity Interval Training in People with Type 2 Diabetes
Principal Advisor
Other advisors: Dr Shelley Keating
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2019
Doctor Philosophy
The feasibility, safety, adherence, and efficacy of high intensity interval training in rehabilitation for coronary heart disease.
Principal Advisor
Other advisors: Dr Shelley Keating
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2019
Doctor Philosophy
Methods and therapies for measuring and managing oxidative stress
Principal Advisor
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2019
Doctor Philosophy
The Effects of Hot Water Immersion on Recovery, Performance and Adaptation to Resistance Exercise.
Principal Advisor
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2018
Doctor Philosophy
The Role of Phytochemicals in Modulating Intrinsic Human Cellular Defence Processes
Principal Advisor
Other advisors: Professor Robert Fassett, Dr David Briskey
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2017
Doctor Philosophy
Fitness and Clinical Outcomes in Liver Transplantation
Principal Advisor
Other advisors: Associate Professor Graeme Macdonald
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2017
Doctor Philosophy
A high intensity interval training intervention in children with obesity
Principal Advisor
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2016
Doctor Philosophy
Different volumes of high-intensity interval training in individuals with metabolic syndrome: how low can you go?
Principal Advisor
Other advisors: Professor Robert Fassett
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2015
Doctor Philosophy
Exercise and Lifestyle Intervention and High Intensity Interval Training in Patients with Chronic Kidney Disease
Principal Advisor
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2014
Doctor Philosophy
O-GlcNAc modification of skeletal muscle proteins in response to exercise
Principal Advisor
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2014
Doctor Philosophy
Cellular, molecular and physiological effects of post-resistance exercise cold water immersion: Implications for subsequent performance
Principal Advisor
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2013
Doctor Philosophy
Heart rate variability as a tool to monitor cardiac parasympathetic function during short- and long-term recovery from exercise
Principal Advisor
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2012
Doctor Philosophy
Exercise and Lifestyle Intervention in patients with Chronic Kidney Disease
Principal Advisor
-
2012
Doctor Philosophy
Significance, assessment and therapy of subclinical cardiac autonomic neuropathy in patients with type 2 diabetes
Principal Advisor
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2011
Doctor Philosophy
Exercise, RhoA and Cardioprotection
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe, Professor Robert Fassett
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2010
Doctor Philosophy
Quantifying oxidative stress and its role in mitochondrial biogenesis
Principal Advisor
Other advisors: Professor Robert Fassett
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2008
Doctor Philosophy
The effects of atorvastatin on kidney function and arterial stiffness in patients with chronic kidney disease
Principal Advisor
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2008
Doctor Philosophy
The Effect of Lifestyle Modification on Type 2 Diabetic Myocardium
Principal Advisor
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2008
Doctor Philosophy
The efficacy of bile pigment supplementation: In vitro and in vivo considerations
Principal Advisor
Other advisors: Professor Joanne Blanchfield, Emeritus Professor Istvan Toth
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2006
Doctor Philosophy
THE INFLUENCE OF BOVINE COLOSTRUM SUPPLEMENTATION ON IMMUNE VARIABLES AND EXERCISE PERFORMANCE IN TRAINED CYCLISTS
Principal Advisor
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2005
Doctor Philosophy
EXERCISE TRAINING, ANTIOXIDANT SUPPLEMENTATION AND THE ENDOTHELIAL CELL
Principal Advisor
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2005
Doctor Philosophy
CYCLOSPORINE A INDUCED ALTERATIONS TO ENDOTHELIAL FUNCTION AND ERYTHROCYTE AND PLASMA REDOX BALANCE, AND THE BENEFITS OF ANTIOXIDANT SUPPLEMENTATION
Principal Advisor
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2005
Master Philosophy
EFFECTS OF ANTIOXIDANT SUPPLEMENTATION IN RENAL TRANSPLANT RECIPIENTS
Principal Advisor
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2004
Doctor Philosophy
Exercise intensity and mode effects on neutrophil activation
Principal Advisor
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2004
Doctor Philosophy
HAEMODYNAMICS OF EXERSICE IN HEALTH, AGEING AND HYPERCHOLESTEROLAEMIA
Principal Advisor
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2002
Master Science
THE EFFECT OF LOW-DENDSITY LIPOPROTEINS ON VASCULAR ENDOTHELIAL FUNCTION IN HAEMODIALYSIS PATIENTS.
Principal Advisor
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2024
Doctor Philosophy
Exercise, Digital Health and Chronic Disease: Feasibility, Effectiveness and Uptake
Associate Advisor
Other advisors: Dr Shelley Keating
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2024
Doctor Philosophy
Understanding the Influence of Passive Heat Therapy and Heat Stress Duration on Cardiovascular and Cerebrovascular Function in Middle and Older Age Adults
Associate Advisor
Other advisors: Dr Tom Bailey
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2024
Doctor Philosophy
The interaction between exercise, diet and adiposity; how can we best promote cardiometabolic health in children and adolescents?
Associate Advisor
Other advisors: Dr Tom Bailey
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2023
Doctor Philosophy
"Stepping up" exercise for type 2 diabetes: a stepped care approach to lifestyle therapy
Associate Advisor
Other advisors: Dr Shelley Keating
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2023
Doctor Philosophy
Understanding the effects of blood pressure and menopause on peripheral and cerebrovascular function in middle-aged and older adults
Associate Advisor
Other advisors: Dr Tom Bailey
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2023
Doctor Philosophy
The implications of age and sex on cerebrovascular regulation across the adult lifespan
Associate Advisor
Other advisors: Dr Tom Bailey
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2020
Doctor Philosophy
Enhancing Language Learning in Ageing with Exercise
Associate Advisor
Other advisors: Professor David Copland
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2019
Doctor Philosophy
Assessment of Sarcopenia, Hepatic Function and Clinical Outcomes in Liver Transplantation
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
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2019
Doctor Philosophy
Kidney Function following Surgical Management of Kidney Cancer
Associate Advisor
Other advisors: Professor Susan Jordan, Associate Professor Ross Francis
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2015
Doctor Philosophy
IDENTIFICATION OF POTENTIAL MEDIATORS OF OXIDATIVE DAMAGE AND TARGETS FOR NOVEL TREATMENTS FOR CHRONIC KIDNEY DISEASE
Associate Advisor
Other advisors: Professor David Johnson
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2011
Doctor Philosophy
Effects of Caffeine Dose and Timing on Exercise Performance
Associate Advisor
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2011
Doctor Philosophy
Effect of Intervention on Cardiovascular Pathophysiology in Diastolic Dysfunction
Associate Advisor
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2006
Doctor Philosophy
THE ROLE OF IMMUNE DISTURBANCES IN THE PATHOLOGY OF HEAT STROKE: THE DUAL PATHWAY MODEL OF HEAT STROKE
Associate Advisor
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2005
Doctor Philosophy
INFLAMMATION AND CARDIOVASCULAR REMODELLING
Associate Advisor
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2004
Doctor Philosophy
THE INFLUENCE OF HIGH-INTENSITY INTERVAL TRAINING IN ALREADY HIGHLY-TRAINED ATHLETES
Associate Advisor
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2004
Doctor Philosophy
ULTRA-ENDURANCE EXERCISE, OXIDATIVE STRESS AND ARTERIAL STIFFNESS
Associate Advisor
Media
Enquiries
Contact Professor Jeff Coombes directly for media enquiries about:
- Antioxidants
- Apoptosis
- Athletes - performance
- Cardiovascular disease
- Diet
- Exercise
- Fitness
- Health
- Heart attack
- Nutrition - sport
- Oxidative stress
- Sport nutrition
- Sport performance
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