
Overview
Background
Jeff Coombes is a Professor in the School of Human Movement Studies. He completed undergraduate degrees in applied science and education and a research Masters at the University of Tasmania before gaining a PhD from the University of Florida. After completing his PhD he returned to Australia to spend two years in an academic position at the University of Tasmania before moving to the University of Queensland in 2000.
Jeff's research interests focus on determining the optimal exercise prescription for improving health. With theoretical backgrounds in biochemistry and physiology he conducts human studies and basic science projects. His findings have emphasised the importance of cardiorespiratory fitness for health benefits and many of his current projects are using high intensity interval to improve fitness and investigate outcomes. The basic science projects are identifying the mechanisms that explain the health benefits of exercise and include work in the cardiovascular and musculoskeletal systems at cellular and molecular levels. He is also a passionate advocate on the importance of fitness for health and delivers many presentations to impact on public health. His research group comprises doctors, postdoctoral fellows and PhD students and uses the extensive resources of the exercise physiology and exercise biochemistry laboratories in the School of Human Movement and Nutrition Sciences.
Current research projects of the group include;
- High intensity interval training in patients with chronic kidney disease
- High intensity interval training in patients with metabolic syndrome
- High intensity interval training in overweight and obese children and adolescents
- Cardiorespiratory fitness and outcome in patients receiving a liver transplant
- Multi-disciplinary lifestyle intervention in patients with chronic kidney disease
- Exercise training in patients with diabetic cardiac autonomic neuropathy
- Oxidative stress and antioxidant biomarkers to predict the cardiorespiratory fitness response to exercise
- Molecular mechanisms of exercise cardioprotection: relations with oxidative stress
- Activation of NRF2 by nutritional supplementation in patients with type 2 diabetes
- Exercise-training and skeletal muscle O-glycnacylation
- Antioxidant supplementation in health and disease
Availability
- Professor Jeff Coombes is:
- Available for supervision
- Media expert
Fields of research
Research interests
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Exercise is Medicine
Works
Search Professor Jeff Coombes’s works on UQ eSpace
2017
Journal Article
Study protocol for the FITR Heart Study: feasibility, safety, adherence, and efficacy of high intensity interval training in a hospital-initiated rehabilitation program for coronary heart disease
Taylor, Jenna, Keating, Shelley E., Leveritt, Michael D., Holland, David J., Gomersall, Sjaan R. and Coombes, Jeff S (2017). Study protocol for the FITR Heart Study: feasibility, safety, adherence, and efficacy of high intensity interval training in a hospital-initiated rehabilitation program for coronary heart disease. Contemporary Clinical Trials Communications, 8, 181-191. doi: 10.1016/j.conctc.2017.10.002
2017
Journal Article
The Correlates of Kidney Dysfunction - Tumour Nephrectomy Database (CKD-TUNED) study: protocol for a prospective observational study
Ellis, Robert J., Del Vecchio, Sharon J., Ng, Keng Lim, Owens, Evan P., Coombes, Jeff S., Morais, Christudas, Francis, Ross S., Wood, Simon T. and Gobe, Glenda C. (2017). The Correlates of Kidney Dysfunction - Tumour Nephrectomy Database (CKD-TUNED) study: protocol for a prospective observational study. Asian Pacific Journal of Cancer Prevention, 18 (12), 3281-3285. doi: 10.22034/APJCP.2017.18.12.3281
2017
Journal Article
Genes to predict VO2max trainability: a systematic review
Williams, Camilla J., Williams, Mark G., Eynon, Nir, Ashton, Kevin J., Little, Jonathan P., Wisloff, Ulrik and Coombes, Jeff S. (2017). Genes to predict VO2max trainability: a systematic review. BMC Genomics, 18 (Suppl 8) 831, 81-110. doi: 10.1186/s12864-017-4192-6
2017
Journal Article
Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study
Ellis, Robert J., Del Vecchio, Sharon J., Ng, Keng Lim, Dimeski, Goce, Pascoe, Elaine M., Hawley, Carmel M., Johnson, David W., Vesey, David A., Coombes, Jeff S., Morais, Christudas, Francis, Ross S., Wood, Simon T. and Gobe, Glenda C. (2017). Factors associated with acutely elevated serum creatinine following radical tumour nephrectomy: the Correlates of Kidney Dysfunction-Tumour Nephrectomy Database study. Translational Andrology and Urology, 6 (5), 899-909. doi: 10.21037/tau.2017.08.15
2017
Journal Article
Exercise intensity, redox homeostasis and inflammation in type 2 diabetes mellitus
Mallard, Alistair R., Hollekim-Strand, Siri Marte, Coombes, Jeff S. and Ingul, Charlotte B. (2017). Exercise intensity, redox homeostasis and inflammation in type 2 diabetes mellitus. Journal of Science and Medicine in Sport, 20 (10), 893-898. doi: 10.1016/j.jsams.2017.03.014
2017
Journal Article
Effect of high-intensity interval training on fitness, fat mass and cardiometabolic biomarkers in children with obesity: a randomised controlled trial
Dias, Katrin A., Ingul, Charlotte B., Tjønna, Arnt E., Keating, Shelley E., Gomersall, Sjaan R., Follestad, Turid, Hosseini, Mansoureh S., Hollekim-Strand, Siri M., Ro, Torstein B., Haram, Margrete, Huuse, Else Marie, Davies, Peter S. W., Cain, Peter A., Leong, Gary M. and Coombes, Jeff S. (2017). Effect of high-intensity interval training on fitness, fat mass and cardiometabolic biomarkers in children with obesity: a randomised controlled trial. Sports Medicine, 48 (3), 1-14. doi: 10.1007/s40279-017-0777-0
2017
Journal Article
The feasibility and acceptability of high-intensity interval training for adults with mental illness: a pilot study
Chapman, Justin J., Coombes, Jeff S., Brown, Wendy J., Khan, Asaduzzaman, Chamoli, Suneel, Pachana, Nancy A. and Burton, Nicola W. (2017). The feasibility and acceptability of high-intensity interval training for adults with mental illness: a pilot study. Mental Health and Physical Activity, 13, 40-48. doi: 10.1016/j.mhpa.2017.09.007
2017
Journal Article
Low-volume high-intensity interval training is sufficient to ameliorate the severity of metabolic syndrome
Ramos, Joyce S., Dalleck, Lance C., Borrani, Fabio, Beetham, Kassia S., Wallen, Matthew P., Mallard, Alistair R., Clark, Bronwyn, Gomersall, Sjaan, Keating, Shelley E., Fassett, Robert G. and Coombes, Jeff S. (2017). Low-volume high-intensity interval training is sufficient to ameliorate the severity of metabolic syndrome. Metabolic Syndrome and Related Disorders, 15 (7), 319-328. doi: 10.1089/met.2017.0042
2017
Journal Article
Impact of beta‐blockers on cardiopulmonary exercise testing in patients with advanced liver disease
Wallen, M. P., Hall, A., Dias, K. A., Ramos, J. S., Keating, S. E., Woodward, A. J., Skinner, T. L., Macdonald, G. A., Arena, R. and Coombes, J. S. (2017). Impact of beta‐blockers on cardiopulmonary exercise testing in patients with advanced liver disease. Alimentary Pharmacology and Therapeutics, 46 (8), 1-7. doi: 10.1111/apt.14265
2017
Journal Article
A systematic review and meta-analysis of interval training versus moderate-intensity continuous training on body adiposity
Keating, S. E., Johnson, N. A., Mielke, G. I. and Coombes, J. S. (2017). A systematic review and meta-analysis of interval training versus moderate-intensity continuous training on body adiposity. Obesity Reviews, 18 (8), 943-964. doi: 10.1111/obr.12536
2017
Journal Article
High-intensity interval training and cardiac autonomic control in individuals with metabolic syndrome: A randomised trial
Ramos, Joyce S., Dalleck, Lance C., Borrani, Fabio, Beetham, Kassia S., Mielke, Gregore Iven, Dias, Katrin A., Wallen, Matthew P., Keating, Shelley E., Fassett, Robert G. and Coombes, Jeff S. (2017). High-intensity interval training and cardiac autonomic control in individuals with metabolic syndrome: A randomised trial. International Journal of Cardiology, 245, 245-252. doi: 10.1016/j.ijcard.2017.07.063
2017
Journal Article
NAFLD in clinical practice: can simple blood and anthropometric markers be used to detect change in liver fat measured by 1H-MRS?
Keating, Shelley E., Parker, Helen M., Hickman, Ingrid J., Gomersall, Sjann R., Wallen, Matthew P., Coombes, Jeff S., Macdonald, Graeme A., George, Jacob and Johnson, Nathan A. (2017). NAFLD in clinical practice: can simple blood and anthropometric markers be used to detect change in liver fat measured by 1H-MRS?. Liver International, 37 (12), 1907-1915. doi: 10.1111/liv.13488
2017
Conference Publication
Effect of Differential Exercise Intensities on Interleukin-22 in Metabolic Syndrome
Ramos, Joyce S., Dalleck, Lance C., Mielke, Gregore I., Keating, Shelley E., McGuckin, Michael, Murray, Lydia S., Hasnain, Sumaira, Fassett, Robert G. and Coombes, Jeff S. (2017). Effect of Differential Exercise Intensities on Interleukin-22 in Metabolic Syndrome. Annual Meeting of the American-College-of-Sports-Medicine (ACSM), Denver Co, May 30-Jun 03, 2017. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. doi: 10.1249/01.mss.0000519264.21081.61
2017
Conference Publication
Chronic and Acute Effects of Hot Water Immersion on Strength, Recovery and Hypertrophy
Peake, Jonathan, McGorm, Hamish, Roberts, Llion, Coombes, Jeff, Cameron‐Smith, David and Raastad, Truls (2017). Chronic and Acute Effects of Hot Water Immersion on Strength, Recovery and Hypertrophy. Experimental Biology 2017 Meeting, Chicago, IL United States, 22-26 April 2017. Hoboken, NJ United States: John Wiley & Sons. doi: 10.1096/fasebj.31.1_supplement.lb735
2017
Journal Article
Left ventricular morphology and function in adolescents: relations to fitness and fatness
Dias, Katrin A., Spence, Angela L., Sarma, Satyam, Oxborough, David, Timilsina, Anita S., Davies, Peter S. W., Cain, Peter A., Leong, Gary M., Ingul, Charlotte B. and Coombes, Jeff S. (2017). Left ventricular morphology and function in adolescents: relations to fitness and fatness. International Journal of Cardiology, 240, 313-319. doi: 10.1016/j.ijcard.2017.03.047
2017
Journal Article
Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise
Cully, Tanya R., Murphy, Robyn M., Roberts, Llion, Raastad, Truls, Fassett, Robert G., Coombes, Jeff S., Jayasinghe, Isuru D. and Launikonis, Bradley S. (2017). Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise. Nature Communications, 8 (1) 14266, 14266.1-14266.10. doi: 10.1038/ncomms14266
2017
Journal Article
Assessment of the five-minute oxygen uptake efficiency slope in children with obesity
Dias, Katrin A., Masterson, Concetta E., Wallen, Matthew P., Tjonna, Arnt E., Hosseini, Mansoureh S., Davies, Peter S. W., Cain, Peter A., Leong, Gary M., Arena, Ross, Inqul, Charlotte B. and Coombes, Jeff S. (2017). Assessment of the five-minute oxygen uptake efficiency slope in children with obesity. Pediatric Exercise Science, 29 (3), 350-360. doi: 10.1123/pes.2016-0248
2017
Journal Article
Prediction of cardiovascular mortality by estimated cardiorespiratory fitness independent of traditional risk factors: the HUNT study
Nauman, Javaid, Nes, Bjarne M., Lavie, Carl J., Jackson, Andrew S., Sui, Xuemei, Coombes, Jeff S., Blair, Steven N. and Wisløff, Ulrik (2017). Prediction of cardiovascular mortality by estimated cardiorespiratory fitness independent of traditional risk factors: the HUNT study. Mayo Clinic Proceedings, 92 (2), 218-227. doi: 10.1016/j.mayocp.2016.10.007
2017
Conference Publication
Establishing a Chronic Kidney Disease Biobank in Queensland to Support Future Research
Owens, E. P., Hoy, W., Coombes, J. S. and Gobe, G. (2017). Establishing a Chronic Kidney Disease Biobank in Queensland to Support Future Research. 53rd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Darwin, Northern Territory, 4–6 September 2017. HOBOKEN: WILEY.
2017
Conference Publication
The Distinguishing Risk of Progressive Chronic Kidney Disease (Drop Ckd) Study
Owens, E. P., Hoy, W., Coombes, J. S., Endre, Z. H. and Gobe, G. (2017). The Distinguishing Risk of Progressive Chronic Kidney Disease (Drop Ckd) Study. 53rd Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Darwin, Northern Territory, 4–6 September 2017. HOBOKEN: WILEY.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jeff Coombes is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Exercise training on people with severe chronic, clinically unexplained gastrointestinal symptoms: A randomised, controlled trial.
Principal Advisor
Other advisors: Professor Gerald Holtmann
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Doctor Philosophy
Exercise Training in People with Mild Cognitive Impairment
Principal Advisor
Other advisors: Dr Shelley Keating
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Doctor Philosophy
Exercise Training in People with Mild Cognitive Impairment
Principal Advisor
Other advisors: Dr Shelley Keating
-
Master Philosophy
Structured exercise program to reduce fatigue in patients receiving dialysis: an adaptive trial (M-FIT)
Principal Advisor
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Doctor Philosophy
Exercise Training and Body Composition in Children and Adolescents with Congenital Heart Disease
Principal Advisor
Other advisors: Dr Shelley Keating
-
Doctor Philosophy
Exercise and Anti-Obesity Medications
Principal Advisor
Other advisors: Dr Riley Brown, Dr Shelley Keating
-
Doctor Philosophy
Exercise Training and Body Composition in Children and Adolescents with Congenital Heart Disease
Principal Advisor
Other advisors: Dr Shelley Keating
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Master Philosophy
Assessment of muscle mass hepatic function and outcomes in patients awaiting liver transplantation
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
-
Doctor Philosophy
Exercise training for cerebrovascular health in perimenopausal women
Associate Advisor
Other advisors: Dr Jenna Taylor
-
Doctor Philosophy
The Design, Establishment and Effectiveness of a Rehabilitation Pathway for Individuals with Postural Orthostatic Tachycardia Syndrome (POTS)
Associate Advisor
Other advisors: Dr Jenna Taylor
Completed supervision
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2022
Doctor Philosophy
Comparison of Low-Volume, High-Intensity Aerobic and Resistance Interval Training with Current Exercise Recommendations on Cardiometabolic Outcomes in People with Type 2 Diabetes
Principal Advisor
Other advisors: Emeritus Professor Wendy Brown, Dr Shelley Keating
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2022
Doctor Philosophy
Effects of Fitness and Exercise Training on Vascular Function in older adults with Mild Cognitive Impairment: Role of Age and Sex
Principal Advisor
Other advisors: Dr Tom Bailey
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2021
Doctor Philosophy
The Effects of Exercise on Early Markers of Cardiovascular Disease Risk in Those Living with and Beyond Cancer
Principal Advisor
Other advisors: Dr Tom Bailey
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2021
Doctor Philosophy
Predicting and improving aerobic exercise training response
Principal Advisor
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2020
Doctor Philosophy
The physiological, morphological and functional responses to resistance exercise with blood flow restriction: An examination of protocol type and exercise load
Principal Advisor
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2020
Doctor Philosophy
The Physiological, Biochemical and Psychological Effects of Low-Volume Combined Aerobic and Resistance High-Intensity Interval Training in People with Type 2 Diabetes
Principal Advisor
Other advisors: Dr Shelley Keating
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2019
Doctor Philosophy
The feasibility, safety, adherence, and efficacy of high intensity interval training in rehabilitation for coronary heart disease.
Principal Advisor
Other advisors: Dr Shelley Keating
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2019
Doctor Philosophy
Methods and therapies for measuring and managing oxidative stress
Principal Advisor
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2019
Doctor Philosophy
The Effects of Hot Water Immersion on Recovery, Performance and Adaptation to Resistance Exercise.
Principal Advisor
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2018
Doctor Philosophy
The Role of Phytochemicals in Modulating Intrinsic Human Cellular Defence Processes
Principal Advisor
Other advisors: Professor Robert Fassett, Dr David Briskey
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2017
Doctor Philosophy
Fitness and Clinical Outcomes in Liver Transplantation
Principal Advisor
Other advisors: Associate Professor Graeme Macdonald
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2017
Doctor Philosophy
A high intensity interval training intervention in children with obesity
Principal Advisor
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2016
Doctor Philosophy
Different volumes of high-intensity interval training in individuals with metabolic syndrome: how low can you go?
Principal Advisor
Other advisors: Professor Robert Fassett
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2015
Doctor Philosophy
Exercise and Lifestyle Intervention and High Intensity Interval Training in Patients with Chronic Kidney Disease
Principal Advisor
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2014
Doctor Philosophy
O-GlcNAc modification of skeletal muscle proteins in response to exercise
Principal Advisor
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2014
Doctor Philosophy
Cellular, molecular and physiological effects of post-resistance exercise cold water immersion: Implications for subsequent performance
Principal Advisor
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2013
Doctor Philosophy
Heart rate variability as a tool to monitor cardiac parasympathetic function during short- and long-term recovery from exercise
Principal Advisor
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2012
Doctor Philosophy
Exercise and Lifestyle Intervention in patients with Chronic Kidney Disease
Principal Advisor
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2012
Doctor Philosophy
Significance, assessment and therapy of subclinical cardiac autonomic neuropathy in patients with type 2 diabetes
Principal Advisor
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2011
Doctor Philosophy
Exercise, RhoA and Cardioprotection
Principal Advisor
Other advisors: Associate Professor Barbara Rolfe, Professor Robert Fassett
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2010
Doctor Philosophy
Quantifying oxidative stress and its role in mitochondrial biogenesis
Principal Advisor
Other advisors: Professor Robert Fassett
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2008
Doctor Philosophy
The effects of atorvastatin on kidney function and arterial stiffness in patients with chronic kidney disease
Principal Advisor
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2008
Doctor Philosophy
The Effect of Lifestyle Modification on Type 2 Diabetic Myocardium
Principal Advisor
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2008
Doctor Philosophy
The efficacy of bile pigment supplementation: In vitro and in vivo considerations
Principal Advisor
Other advisors: Professor Joanne Blanchfield, Emeritus Professor Istvan Toth
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2006
Doctor Philosophy
THE INFLUENCE OF BOVINE COLOSTRUM SUPPLEMENTATION ON IMMUNE VARIABLES AND EXERCISE PERFORMANCE IN TRAINED CYCLISTS
Principal Advisor
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2005
Doctor Philosophy
CYCLOSPORINE A INDUCED ALTERATIONS TO ENDOTHELIAL FUNCTION AND ERYTHROCYTE AND PLASMA REDOX BALANCE, AND THE BENEFITS OF ANTIOXIDANT SUPPLEMENTATION
Principal Advisor
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2005
Doctor Philosophy
EXERCISE TRAINING, ANTIOXIDANT SUPPLEMENTATION AND THE ENDOTHELIAL CELL
Principal Advisor
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2005
Master Philosophy
EFFECTS OF ANTIOXIDANT SUPPLEMENTATION IN RENAL TRANSPLANT RECIPIENTS
Principal Advisor
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2004
Doctor Philosophy
Exercise intensity and mode effects on neutrophil activation
Principal Advisor
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2004
Doctor Philosophy
HAEMODYNAMICS OF EXERSICE IN HEALTH, AGEING AND HYPERCHOLESTEROLAEMIA
Principal Advisor
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2002
Master Science
THE EFFECT OF LOW-DENDSITY LIPOPROTEINS ON VASCULAR ENDOTHELIAL FUNCTION IN HAEMODIALYSIS PATIENTS.
Principal Advisor
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2024
Doctor Philosophy
Exercise, Digital Health and Chronic Disease: Feasibility, Effectiveness and Uptake
Associate Advisor
Other advisors: Dr Shelley Keating
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2024
Doctor Philosophy
The interaction between exercise, diet and adiposity; how can we best promote cardiometabolic health in children and adolescents?
Associate Advisor
Other advisors: Dr Tom Bailey
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2024
Doctor Philosophy
Understanding the Influence of Passive Heat Therapy and Heat Stress Duration on Cardiovascular and Cerebrovascular Function in Middle and Older Age Adults
Associate Advisor
Other advisors: Dr Tom Bailey
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2023
Doctor Philosophy
"Stepping up" exercise for type 2 diabetes: a stepped care approach to lifestyle therapy
Associate Advisor
Other advisors: Dr Shelley Keating
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2023
Doctor Philosophy
Understanding the effects of blood pressure and menopause on peripheral and cerebrovascular function in middle-aged and older adults
Associate Advisor
Other advisors: Dr Tom Bailey
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2023
Doctor Philosophy
The implications of age and sex on cerebrovascular regulation across the adult lifespan
Associate Advisor
Other advisors: Dr Tom Bailey
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2020
Doctor Philosophy
Enhancing Language Learning in Ageing with Exercise
Associate Advisor
Other advisors: Professor David Copland
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2019
Doctor Philosophy
Assessment of Sarcopenia, Hepatic Function and Clinical Outcomes in Liver Transplantation
Associate Advisor
Other advisors: Associate Professor Graeme Macdonald
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2019
Doctor Philosophy
Kidney Function following Surgical Management of Kidney Cancer
Associate Advisor
Other advisors: Professor Susan Jordan, Associate Professor Ross Francis
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2015
Doctor Philosophy
IDENTIFICATION OF POTENTIAL MEDIATORS OF OXIDATIVE DAMAGE AND TARGETS FOR NOVEL TREATMENTS FOR CHRONIC KIDNEY DISEASE
Associate Advisor
Other advisors: Professor David Johnson
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2011
Doctor Philosophy
Effects of Caffeine Dose and Timing on Exercise Performance
Associate Advisor
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2011
Doctor Philosophy
Effect of Intervention on Cardiovascular Pathophysiology in Diastolic Dysfunction
Associate Advisor
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2006
Doctor Philosophy
THE ROLE OF IMMUNE DISTURBANCES IN THE PATHOLOGY OF HEAT STROKE: THE DUAL PATHWAY MODEL OF HEAT STROKE
Associate Advisor
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2005
Doctor Philosophy
INFLAMMATION AND CARDIOVASCULAR REMODELLING
Associate Advisor
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2004
Doctor Philosophy
THE INFLUENCE OF HIGH-INTENSITY INTERVAL TRAINING IN ALREADY HIGHLY-TRAINED ATHLETES
Associate Advisor
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2004
Doctor Philosophy
ULTRA-ENDURANCE EXERCISE, OXIDATIVE STRESS AND ARTERIAL STIFFNESS
Associate Advisor
Media
Enquiries
Contact Professor Jeff Coombes directly for media enquiries about:
- Antioxidants
- Apoptosis
- Athletes - performance
- Cardiovascular disease
- Diet
- Exercise
- Fitness
- Health
- Heart attack
- Nutrition - sport
- Oxidative stress
- Sport nutrition
- Sport performance
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