Professor Mark Walker
Professor

Mark Walker

Email: 
Phone: 
+61 7 334 61623

Availability

Professor Mark Walker is:
Available for supervision
Media expert

Fields of research

Biological Sciences Medical microbiology Microbiology

Qualifications

  • Doctor of Philosophy, The University of Queensland

Search Professor Mark Walker’s works on UQ eSpace

308 works between 1967 and 2026
All (308) Journal Article (276) Conference Publication (26) Book Chapter (6)

141 - 160 of 308 works

2013

Journal Article

Spectre of the stranger

Walker, Mark J. (2013). Spectre of the stranger. European Journal of Psychotherapy & Counselling, 15 (3), 303-305. doi: 10.1080/13642537.2013.814420

Spectre of the stranger

2013

Book Chapter

Group A streptococcal vaccine candidates: potential for the development of a human vaccine

Henningham, Anna, Gillen, Christine M. and Walker, Mark J. (2013). Group A streptococcal vaccine candidates: potential for the development of a human vaccine. Host-pathogen interactions in streptococcal diseases. (pp. 207-242) edited by G. Singh Chhatwal. New York, NY, United States: Springer. doi: 10.1007/82_2012_284

Group A streptococcal vaccine candidates: potential for the development of a human vaccine

2013

Journal Article

Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus

Tsatsaronis, James A., Hollands, Andrew, Cole, Jason N., Maamary, Peter G., Gillen, Christine M., Ben Zakour, Nouri L., Kotb, Malak, Nizet, Victor, Beatson, Scott A., Mark J. Walker and Sanderson-Smith, Martina L. (2013). Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus. FASEB Journal, 27 (7), 2633-2643. doi: 10.1096/fj.12-226662

Streptococcal collagen-like protein A and general stress protein 24 are immunomodulating virulence factors of group A Streptococcus

2013

Conference Publication

Accurate Pose Determination for Autonomous Vehicle Navigation

Walker, Mark J. and Sasiadek, Jurek Z. (2013). Accurate Pose Determination for Autonomous Vehicle Navigation. 18th International Conference on Methods and Models in Automation and Robotics (MMAR), Miedzyzdroje Poland, Aug 26-29, 2013. NEW YORK: IEEE.

Accurate Pose Determination for Autonomous Vehicle Navigation

2012

Journal Article

Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates

Woolley, Lauren K., Fell, Shayne, Gonsalves, Jocelyn R., Walker, Mark J., Djordjevic, Steven P., Jenkins, Cheryl and Eamens, Graeme J. (2012). Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates. Veterinary Microbiology, 161 (1-2), 186-195. doi: 10.1016/j.vetmic.2012.07.025

Evaluation of clinical, histological and immunological changes and qPCR detection of Mycoplasma hyopneumoniae in tissues during the early stages of mycoplasmal pneumonia in pigs after experimental challenge with two field isolates

2012

Journal Article

Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis

Cook, Simon M., Skora, Amanda, Gillen, Christine M., Walker, Mark J. and McArthur, Jason D. (2012). Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis. Molecular Microbiology, 86 (5), 1052-1062. doi: 10.1111/mmi.12037

Streptokinase variants from Streptococcus pyogenes isolates display altered plasminogen activation characteristics - implications for pathogenesis

2012

Journal Article

Outsmarting outbreaks

Walker, Mark J. and Beatson, Scott A. (2012). Outsmarting outbreaks. Science, 338 (6111), 1161-1162. doi: 10.1126/science.1232327

Outsmarting outbreaks

2012

Journal Article

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

Maamary, Peter G., Ben Zakour, Nouri L., Cole, Jason N., Hollands, Andrew, Aziz, Ramy K., Barnett, Timothy C., Cork, Amanda J., Henningham, Anna, Sanderson-Smith, Martina, McArthur, Jason D., Venturini, Carola, Gillen, Christine M., Kirk, Joshua K., Johnson, Dwight R., Taylor, William L., Kaplan, Edward L., Kotb, Malak, Nizet, Victor, Beatson, Scott A. and Walker, Mark J. (2012). Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone. FASEB Journal, 26 (11), 4675-4684. doi: 10.1096/fj.12-212142

Tracing the evolutionary history of the pandemic group A streptococcal M1T1 clone

2012

Journal Article

Molecular characterization of the 2011 Hong Kong scarlet fever outbreak

Tse, Herman, Bao, Jessie Y. J., Davies, Mark R., Maamary, Peter, Tsoi, Hoi-Wah, Tong, Amy H. Y., Ho, Tom C. C., Lin, Chi-Ho, Gillen, Christine M., Barnett, Timothy C., Chen, Jonathan H. K., Lee, Mianne, Yam, Wing-Cheong, Wong, Chi-Kin, Ong, Cheryl-lynn Y., Chan, Yee-Wai, Wu, Cheng-Wei, Ng, Tony, Lim, Wilina W. L., Tsang, Thomas H. F., Tse, Cindy W. S., Dougan, Gordon, Walker, Mark J., Lok, Si and Yuen, Kwok-Yung (2012). Molecular characterization of the 2011 Hong Kong scarlet fever outbreak. The Journal of Infectious Diseases, 206 (3), 341-351. doi: 10.1093/infdis/jis362

Molecular characterization of the 2011 Hong Kong scarlet fever outbreak

2012

Journal Article

Pathogenesis of group A streptococcal infections

Henningham, Anna, Barnett, Timothy C., Maamary, Peter G. and Walker, Mark J. (2012). Pathogenesis of group A streptococcal infections. Discovery Medicine, 13 (72), 329-342.

Pathogenesis of group A streptococcal infections

2012

Journal Article

Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography

Bogema, Daniel R., Deutscher, Ania T., Woolley, Lauren K., Seymour, Lisa M., Raymond, Benjamin B. A., Tacchi, Jessica L., Padula, Matthew P., Dixon, Nicholas E., Minion, F. Chris, Jenkins, Cheryl, Walker, Mark J. and Djordjevic, Steven P. (2012). Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography. mBio, 3 (2) e00282-11, e00282.1-e00282.11. doi: 10.1128/mBio.00282-11

Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates surface topography

2012

Journal Article

Molecular characterization of a 21.4 kilobase antibiotic resistance plasmid from an alpha-Hemolytic Escherichia coli O108:H- Human Clinical Isolate

Dawes, Fay E., Bulach, Dieter M., Kuzevski, Alexander, Bettelheim, Karl A., Venturini, Carola, Djordjevic, Steven P. and Walker, Mark J. (2012). Molecular characterization of a 21.4 kilobase antibiotic resistance plasmid from an alpha-Hemolytic Escherichia coli O108:H- Human Clinical Isolate. Plos One, 7 (4) e34718, e34718.1-e34718.6. doi: 10.1371/journal.pone.0034718

Molecular characterization of a 21.4 kilobase antibiotic resistance plasmid from an alpha-Hemolytic Escherichia coli O108:H- Human Clinical Isolate

2012

Conference Publication

Mycoplasma hyopneumoniae surface proteins Mhp385 and Mhp384 bind host cilia and glycosaminoglycans and are endoproteolytically processed by proteases that recognize different cleavage motifs

Deutscher, Ania T., Tacchi, Jessica L., Minion, F. Chris, Padula, Matthew P., Crossett, Ben, Bogema, Daniel R., Jenkins, Cheryl, Kuit, Tracey A., Walker, Mark J. and Djordjevic, Steven P. (2012). Mycoplasma hyopneumoniae surface proteins Mhp385 and Mhp384 bind host cilia and glycosaminoglycans and are endoproteolytically processed by proteases that recognize different cleavage motifs. Washington, DC, United States: American Chemical Society. doi: 10.1021/pr201115v

Mycoplasma hyopneumoniae surface proteins Mhp385 and Mhp384 bind host cilia and glycosaminoglycans and are endoproteolytically processed by proteases that recognize different cleavage motifs

2012

Journal Article

The role of streptokinase as a virulence determinant of Streptococcus pyogenes: Potential for therapeutic targeting

McArthur, Jason D., Cook, Simon M., Venturini, Carola and Walker, Mark J. (2012). The role of streptokinase as a virulence determinant of Streptococcus pyogenes: Potential for therapeutic targeting. Current Drug Targets, 13 (3), 297-307. doi: 10.2174/138945012799424589

The role of streptokinase as a virulence determinant of Streptococcus pyogenes: Potential for therapeutic targeting

2012

Journal Article

Polyelectrolyte complex materials consisting of antibacterial and cell-supporting layers

Amin, Khairul Anuar Mat, Gilmore, Kerry J., Matic, Jake, Poon, Stephen, Walker, Mark J., Wilson, Mark R. and Panhuis, Marc In Het (2012). Polyelectrolyte complex materials consisting of antibacterial and cell-supporting layers. Macromolecular Bioscience, 12 (3), 374-382. doi: 10.1002/mabi.201100317

Polyelectrolyte complex materials consisting of antibacterial and cell-supporting layers

2012

Journal Article

Mhp182 (P102) binds fibronectin and contributes to the recruitment of plasmin(ogen) to the Mycoplasma hyopneumoniae cell surface

Seymour, Lisa M., Jenkins, Cheryl, Deutscher, Ania T., Raymond, Benjamin B. A., Padula, Matthew P., Tacchi, Jessica L., Bogema, Daniel R., Eamens, Graeme J., Woolley, Lauren K., Dixon, Nicholas E., Walker , Mark J. and Djordjevic, Steven P. (2012). Mhp182 (P102) binds fibronectin and contributes to the recruitment of plasmin(ogen) to the Mycoplasma hyopneumoniae cell surface. Cellular Microbiology, 14 (1), 81-94. doi: 10.1111/j.1462-5822.2011.01702.x

Mhp182 (P102) binds fibronectin and contributes to the recruitment of plasmin(ogen) to the Mycoplasma hyopneumoniae cell surface

2012

Journal Article

Analysis of a Streptococcus pyogenes puerperal sepsis cluster using whole-genome sequencing

Ben Zakour, Nouri L., Venturini, Carola, Beatson, Scott A. and Walker, Mark J. (2012). Analysis of a Streptococcus pyogenes puerperal sepsis cluster using whole-genome sequencing. Journal of Clinical Microbiology, 50 (7), 2224-2228. doi: 10.1128/JCM.00675-12

Analysis of a Streptococcus pyogenes puerperal sepsis cluster using whole-genome sequencing

2012

Journal Article

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

Henningham, Anna, Chiarot, Emiliano, Gillen, Christine M., Cole, Jason N., Rohde, Manfred, Fulde, Marcus, Ramachandran, Vidiya, Cork, Amanda J., Hartas, Jon, Magor, Graham, Djordjevic, Steven P., Cordwell, Stuart J., Kobe, Bostjan, Sriprakash, Kabada S., Nizet, Victor, Chhatwal, G. S., Margarit, Immaculada Y. R., Batzloff, Michael R. and Walker, Mark J. (2012). Conserved anchorless surface proteins as group A streptococcal vaccine candidates. Journal of Molecular Medicine, 90 (10), 1197-1207. doi: 10.1007/s00109-012-0897-9

Conserved anchorless surface proteins as group A streptococcal vaccine candidates

2012

Journal Article

Establishment of the Australian Infectious Diseases Research Centre

Walker, Mark (2012). Establishment of the Australian Infectious Diseases Research Centre. Current Drug Targets, 13 (11), 1347-1347. doi: 10.2174/138945012803530189

Establishment of the Australian Infectious Diseases Research Centre

2011

Journal Article

Sequence TTKF (down arrow) QE defines the site of proteolytic cleavage in Mhp683 protein, a novel glycosaminoglycan and cilium adhesin of Mycoplasma hyopneumoniae

Bogema, Daniel R., Scott, Nichollas E., Padula, Matthew P., Tacchi, Jessica L., Raymond, Benjamin B. A., Jenkins, Cheryl, Cordwell, Stuart J., Minion, F. Chris, Walker, Mark J. and Djordjevic, Steven P. (2011). Sequence TTKF (down arrow) QE defines the site of proteolytic cleavage in Mhp683 protein, a novel glycosaminoglycan and cilium adhesin of Mycoplasma hyopneumoniae. Journal of Biological Chemistry, 286 (48), 41217-41229. doi: 10.1074/jbc.M111.226084

Sequence TTKF (down arrow) QE defines the site of proteolytic cleavage in Mhp683 protein, a novel glycosaminoglycan and cilium adhesin of Mycoplasma hyopneumoniae

Current funding

  • 2026 - 2030
    Guiding Group A Streptococcus vaccines into clinical development.
    NHMRC Investigator Grants
    Open grant
  • 2024 - 2026
    Novel ionophore combination therapeutic treatment (CARB-X grant administered by University of Melbourne)
    University of Melbourne
    Open grant
  • 2024 - 2026
    Preclinical refinement of a UQ-Moderna vaccine developed to prevent StrepA infection
    NHMRC Development Grant
    Open grant
  • 2024 - 2027
    Screening experimental adjuvants in non-human primates for improved Group A Streptococcus (GAS) vaccine efficacy
    The University of Queensland in America, Inc
    Open grant
  • 2023 - 2026
    Breaking drug resistance in community acquired bacterial pneumonia (CABP) (NHMRC Development grant administered by University of Melbourne)
    University of Melbourne
    Open grant
  • 2022 - 2026
    Mining the host-pathogen interface to deliver a drug pipeline for treating intractable and emerging infections
    NHMRC Synergy Grants
    Open grant
  • 2021 - 2028
    Development of an mRNA vaccine to prevent Group A Streptococcus pharyngeal infection
    ModernaTX, Inc
    Open grant

Past funding

  • 2021 - 2022
    Testing of prototype GSK vaccines in a mouse model of GAS invasive disease.
    GSK Vaccines Institute for Global Health
    Open grant
  • 2021 - 2025
    Scarlet fever pandemic and reversing antibiotic resistance
    NHMRC Investigator Grants
    Open grant
  • 2020 - 2023
    Breaking antibiotic resistance in high priority Gram-negative sepsis pathogens
    NHMRC Development Grant
    Open grant
  • 2019
    A versatile accurate mass, high resolution QTOF mass spectrometer for chemistry and proteomic applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2022
    Deploying next-generation adjuvants to enhance protection of a group A streptococcal vaccine candidate
    NHMRC Development Grant
    Open grant
  • 2019
    In vivo imaging system for tracking inflammation, infection, cancer, pain and bioactive molecules
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Epifluorescent and live-cell imaging microscopes for the investigation of host-pathogen interactions and for molecular and cellular biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2018
    Centre for Geoanalytical Mass Spectrometry (CGMS) - Achieving excellence in isotope geochemistry and geochronology
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2017 - 2019
    Worldwide molecular analysis of Streptococcus pyogenes scarlet fever outbreaks
    NHMRC Project Grant
    Open grant
  • 2016 - 2017
    Facility for characterisation of bionanomaterials
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2016 - 2017
    Evaluation of immunological efficacy and safety parameters of experimental GAS vaccines in non-human primates
    Queensland Emory Development Alliance
    Open grant
  • 2016 - 2020
    Epidemiology, pathogenesis and prevention of group A streptococcal infection
    NHMRC Research Fellowship
    Open grant
  • 2016
    Instrumentation for the analysis of cellular and metabolic phenotypes
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Next-generation multi-collector inductively-coupled plasma mass spectrometer (MC-ICP-MS) with laser-ablation capability for in situ high-throughput and high resolution isotope dating and characterizat
    UQ Major Research Facility Fund
    Open grant
  • 2015 - 2016
    Sequencing and bioinformatics analysis of circulating GAS strains for the CANVAS project (Subcontract to Murdoch Childrens Research Institute under NHMRC Special Initiative administered by UWA)
    Murdoch Childrens Research Institute
    Open grant
  • 2015 - 2020
    GAS Switch from Colonizing Bacterium to Invasive Pathogen (NIH application submitted by University of California, San Diego)
    University of California, San Diego
    Open grant
  • 2015 - 2019
    Proteins and glycans in host-pathogen interactions: targets for novel drugs and vaccines (NHMRC Program Grant administered by The University of Adelaide)
    University of Adelaide
    Open grant
  • 2014 - 2017
    A pan-genome reverse vaccinology approach to disease prevention in farmed fish
    ARC Linkage Projects
    Open grant
  • 2014
    A confocal microscope for investigation of live bacterial and viral pathogens and for molecular cell biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2014 - 2016
    Evolution of bacterial pathogenesis
    ARC Discovery Projects
    Open grant
  • 2014 - 2016
    Non-human primate studies of group A streptococcal vaccine candidates
    NHMRC Development Grant
    Open grant
  • 2013 - 2014
    Development and immunological evaluation of a broadly-protective Group A Streptococcal vaccine, incorporating six highly-conserved protective antigens, in non-human primates
    Queensland Emory Development Alliance
    Open grant
  • 2013 - 2016
    Interaction of group A streptococci with intracellular innate immune defence
    NHMRC Project Grant
    Open grant
  • 2013 - 2014
    Post-genomic analysis of novel Streptococcus pyogenes virulence pathways
    Go8 Australia - Germany Joint Research Co-operation Scheme
    Open grant
  • 2012 - 2013
    A high-throughput screening and sequencing facility for single cell genomics
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2012 - 2013
    Multi angle light scattering detector for the measurement of absolute molecular weight, size, and conformation of macromolecules in solution
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Defining domains within Mycoplasma hyopneumaoniae surface proteins that interact with host extracellular matrix: efficacy testing of candidate vaccines in swine
    ARC Linkage Projects
    Open grant
  • 2011
    Cell culture facilities for studying host-pathogen interactions and immune function
    UQ Major Equipment and Infrastructure
    Open grant
  • 2011
    Mass spectrometer for biomolecule discovery, structural analysis and quantification.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2013
    GAS Switch from Colonizing Bacterium to Invasive Pathogen
    University of California, San Diego
    Open grant
  • 2010 - 2012
    Preclinical studies of group A Streptococcal vaccine candidates
    NHMRC Development Grant
    Open grant
  • 2010 - 2015
    NHMRC Research Fellowship
    NHMRC Research Fellowship
    Open grant
  • 2010 - 2012
    Does viral programming cause group A streptococcal invasive disease?
    NHMRC Project Grant
    Open grant
  • 2010
    An integrated high -throughput fluorescence imaging facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2014
    Pathogenesis, treatment and prevention of bacterial infectious diseases (NHMRC Program Grant administered by the University of Adelaide)
    University of Adelaide
    Open grant
  • 2009 - 2011
    Mapping cell wall and surface structures of Gram-positive cocci
    ARC Discovery Projects
    Open grant

Availability

Professor Mark Walker is:
Available for supervision

Looking for a supervisor? Read our advice on how to choose a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Deploying ex vivo intranasal and tonsillar epithelial models to investigate Streptococcus pyogenes colonisation

    Principal Advisor

    Other advisors: Dr Stephan Brouwer

  • Doctor Philosophy

    Studying the synergistic effects of streptococcal SLO and NADase on toxification of the host redox metabolism

    Principal Advisor

    Other advisors: Professor Kate Schroder, Dr Stephan Brouwer

  • Doctor Philosophy

    Preclinical refinement of a UQ-Moderna vaccine developed to prevent StrepA infection

    Principal Advisor

    Other advisors: Professor Gabrielle Belz

  • Doctor Philosophy

    The contribution of superantigens to the pathogenesis of Streptococcus pyogenes M1UK

    Principal Advisor

    Other advisors: Dr Stephan Brouwer

  • Doctor Philosophy

    Breaking antibiotic resistance in multi-drug resistant Acinetobacter baumanni

    Principal Advisor

    Other advisors: Emeritus Professor Maree Smith

  • Doctor Philosophy

    Discovery and development of an Antibiotic Modulator to Break Antibiotic Resistance in a Mouse Infection Model

    Associate Advisor

    Other advisors: Dr Andy Kuo, Emeritus Professor Maree Smith

Completed supervision

Enquiries

Contact Professor Mark Walker directly for media enquiries about:

  • Cellulitis
  • Disease
  • Impetigo
  • Invasive disease
  • Pharyngitis
  • Scarlet fever
  • Skin infections
  • Streptococcal toxic shock syndrome
  • Streptococcus
  • Toxic shock syndrome

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