Professor

Wally Thomas

Email: 
Phone: 
+61 7 336 51074

Availability

Professor Wally Thomas is:
Available for supervision
Media expert

Fields of research

Biological Sciences Cardiovascular medicine and haematology Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor of Science, The University of Queensland
  • Bachelor (Honours) of Science (Advanced), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Search Professor Wally Thomas’s works on UQ eSpace

174 works between 1985 and 2024
All (174) Journal Article (139) Book Chapter (4) Conference Publication (31)

141 - 160 of 174 works

2000

Journal Article

Agonist-induced phosphorylation of the angiotensin II (AT1A) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling state

Thomas, Walter G., Qian, Hongwei W., Chang, Chang-Sheng and Karnik, Sadashiva (2000). Agonist-induced phosphorylation of the angiotensin II (AT1A) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling state. Journal of Biological Chemistry, 275 (4), 2893-2900. doi: 10.1074/jbc.275.4.2893

Agonist-induced phosphorylation of the angiotensin II (AT1A) receptor requires generation of a conformation that is distinct from the inositol phosphate-signaling state

1999

Journal Article

Identification of protein kinase C phosphorylation sites in the angiotensin II (AT(1A)) receptor

Qian, HW, Pipolo, L and Thomas, WG (1999). Identification of protein kinase C phosphorylation sites in the angiotensin II (AT(1A)) receptor. Biochemical Journal, 343 (3), 637-644. doi: 10.1042/0264-6021:3430637

Identification of protein kinase C phosphorylation sites in the angiotensin II (AT(1A)) receptor

1999

Journal Article

New aspects of angiotensin receptor regulation: Implications for other seven transmembrane-spanning receptors.

Thomas, WG (1999). New aspects of angiotensin receptor regulation: Implications for other seven transmembrane-spanning receptors.. Protein and Peptide Letters, 6 (5), 305-317.

New aspects of angiotensin receptor regulation: Implications for other seven transmembrane-spanning receptors.

1999

Journal Article

Identification of a Ca2+/calmodulin-binding domain within the carboxyl-terminus of the angiotensin II (AT(1A)) receptor

Thomas, WG, Pipolo, L and Qian, HW (1999). Identification of a Ca2+/calmodulin-binding domain within the carboxyl-terminus of the angiotensin II (AT(1A)) receptor. FEBS Letters, 455 (3), 367-371. doi: 10.1016/S0014-5793(99)00904-7

Identification of a Ca2+/calmodulin-binding domain within the carboxyl-terminus of the angiotensin II (AT(1A)) receptor

1999

Journal Article

Regulation of angiotensin II type 1 (AT1) receptor function

Thomas, Walter G. (1999). Regulation of angiotensin II type 1 (AT1) receptor function. Regulatory Peptides, 79 (1), 9-23. doi: 10.1016/S0167-0115(98)00140-2

Regulation of angiotensin II type 1 (AT1) receptor function

1998

Journal Article

Phosphorylation of the angiotensin II (AT(1A)) receptor carboxyl terminus: A role in receptor endocytosis

Thomas, WG, Motel, TJ, Kule, CE, Karoor, V and Baker, KM (1998). Phosphorylation of the angiotensin II (AT(1A)) receptor carboxyl terminus: A role in receptor endocytosis. Molecular Endocrinology, 12 (10), 1513-1524. doi: 10.1210/me.12.10.1513

Phosphorylation of the angiotensin II (AT(1A)) receptor carboxyl terminus: A role in receptor endocytosis

1998

Journal Article

Functional role for the angiotensin II receptor (AT(1A)) 3 '-untranslated region in determining cellular responses to agonist: evidence for recognition by RNA binding proteins

Thekkumkara, TJ, Thomas, WG, Motel, TJ and Baker, KM (1998). Functional role for the angiotensin II receptor (AT(1A)) 3 '-untranslated region in determining cellular responses to agonist: evidence for recognition by RNA binding proteins. Biochemical Journal, 329 (2), 255-264. doi: 10.1042/bj3290255

Functional role for the angiotensin II receptor (AT(1A)) 3 '-untranslated region in determining cellular responses to agonist: evidence for recognition by RNA binding proteins

1996

Journal Article

Cardiac effects of AII: AT1A Receptor Signaling, Desensitization, and Internalization

Thomas, W. G., Thekkumkara, T. J. and Baker, K. M. (1996). Cardiac effects of AII: AT1A Receptor Signaling, Desensitization, and Internalization. Advances in Experimental Medicine and Biology, 396, 59-69.

Cardiac effects of AII: AT1A Receptor Signaling, Desensitization, and Internalization

1996

Conference Publication

Angiotensin II receptor (AT(1A)) endocytosis involves phosphorylation of the carboxyl-terminus ''STL'' internalization motif.

Thomas, WG, Motel, TJ, Kule, CE and Baker, KM (1996). Angiotensin II receptor (AT(1A)) endocytosis involves phosphorylation of the carboxyl-terminus ''STL'' internalization motif.. DALLAS: AMER HEART ASSOC.

Angiotensin II receptor (AT(1A)) endocytosis involves phosphorylation of the carboxyl-terminus ''STL'' internalization motif.

1996

Journal Article

Molecular mechanisms of angiotensin II (AT(1A)) receptor endocytosis

Thomas, WG, Thekkumkara, TJ and Baker, KM (1996). Molecular mechanisms of angiotensin II (AT(1A)) receptor endocytosis. Clinical and Experimental Pharmacology and Physiology, 23, S74-S80.

Molecular mechanisms of angiotensin II (AT(1A)) receptor endocytosis

1996

Journal Article

Evidence against a role for protein kinase C in the regulation of the angiotensin II (AT1A) receptor

Thomas, WG, Baker, KM, Booz, GW and Thekkumkara, TJ (1996). Evidence against a role for protein kinase C in the regulation of the angiotensin II (AT1A) receptor. European Journal of Pharmacology, 295 (1), 119-122. doi: 10.1016/0014-2999(95)00732-6

Evidence against a role for protein kinase C in the regulation of the angiotensin II (AT1A) receptor

1996

Conference Publication

Cardiac effects of AII - AT(1A) receptor signaling, desensitization, and internalization

Thomas, WG, Thekkumkara, TJ and Baker, KM (1996). Cardiac effects of AII - AT(1A) receptor signaling, desensitization, and internalization. 1st International Symposium on the Cellular and Molecular Aspects of Angiotensin Receptors, Gainesville Fl, Dec 09-11, 1994. NEW YORK: PLENUM PRESS DIV PLENUM PUBLISHING CORP.

Cardiac effects of AII - AT(1A) receptor signaling, desensitization, and internalization

1995

Journal Article

Molecular forms of rat angiotensinogen in plasma and brain: identification by isoelectric focusing and immunoblot analysis

Thomas, WG, Kerr, D and Sernia, C (1995). Molecular forms of rat angiotensinogen in plasma and brain: identification by isoelectric focusing and immunoblot analysis. Regulatory Peptides, 59 (1), 31-41. doi: 10.1016/0167-0115(95)00071-I

Molecular forms of rat angiotensinogen in plasma and brain: identification by isoelectric focusing and immunoblot analysis

1995

Conference Publication

An Essential Role for Leu316 and Tyr319 in Angiotensin-Ii (Atia) Receptor Endocytosis

Thomas, WG, Baker, KM, Motel, TJ and Thekkumkara, TJ (1995). An Essential Role for Leu316 and Tyr319 in Angiotensin-Ii (Atia) Receptor Endocytosis. DALLAS: AMER HEART ASSOC.

An Essential Role for Leu316 and Tyr319 in Angiotensin-Ii (Atia) Receptor Endocytosis

1995

Journal Article

Angiotensin-Ii Receptor Endocytosis Involves 2 Distinct Regions Ef the Cytoplasmic Tail - a Role for Residues On the Hydrophobic Face of a Putative Amphipathic Helix

Thomas, WG, Baker, KM, Motel, TJ and Thekkumkara, TJ (1995). Angiotensin-Ii Receptor Endocytosis Involves 2 Distinct Regions Ef the Cytoplasmic Tail - a Role for Residues On the Hydrophobic Face of a Putative Amphipathic Helix. Journal of Biological Chemistry, 270 (38), 22153-22159. doi: 10.1074/jbc.270.38.22153

Angiotensin-Ii Receptor Endocytosis Involves 2 Distinct Regions Ef the Cytoplasmic Tail - a Role for Residues On the Hydrophobic Face of a Putative Amphipathic Helix

1995

Journal Article

Activation of the Stat Pathway by Angiotensin-Ii in T3Cho/at(1A) Cells - Cross-Talk Between Angiotensin-Ii and Interleukin-6 Nuclear Signaling

Bhat, GJ, Thekkumkara, TJ, Thomas, WG, Conrad, KM and Baker, KM (1995). Activation of the Stat Pathway by Angiotensin-Ii in T3Cho/at(1A) Cells - Cross-Talk Between Angiotensin-Ii and Interleukin-6 Nuclear Signaling. Journal of Biological Chemistry, 270 (32), 19059-19065. doi: 10.1074/jbc.270.32.19059

Activation of the Stat Pathway by Angiotensin-Ii in T3Cho/at(1A) Cells - Cross-Talk Between Angiotensin-Ii and Interleukin-6 Nuclear Signaling

1995

Journal Article

Stable expression of a truncated AT1A receptor in CHO-K1 cells: the carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization

Thomas, Walter G., Thekkumkara, Thomas J., Motel, Thomas J. and Baker, Kenneth M. (1995). Stable expression of a truncated AT1A receptor in CHO-K1 cells: the carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization. Journal of Biological Chemistry, 270 (1), 207-213. doi: 10.1074/jbc.270.1.207

Stable expression of a truncated AT1A receptor in CHO-K1 cells: the carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization

1995

Journal Article

Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: Rapid desensitization by angiotensin II

Thekkumkara, TJ, Du, J, Dostal, DE, Motel, TJ, Thomas, WG and Baker, KM (1995). Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: Rapid desensitization by angiotensin II. Molecular and Cellular Biochemistry, 146 (1), 79-89. doi: 10.1007/BF00926885

Stable expression of a functional rat angiotensin II (AT1A) receptor in CHO-K1 cells: Rapid desensitization by angiotensin II

1994

Journal Article

Angiotensin II stimulates sis-inducing factor-like DNA binding activity: evidence that the AT1A receptor activates transcription factor-Stat91 and/or a related protein

Bhat, G. Jayarama, Thekkumkara, Thomas J., Thomas, Walter G., Conrad, Kathleen M. and Baker, Kenneth M. (1994). Angiotensin II stimulates sis-inducing factor-like DNA binding activity: evidence that the AT1A receptor activates transcription factor-Stat91 and/or a related protein. Journal of Biological Chemistry, 269 (50), 31443-31449.

Angiotensin II stimulates sis-inducing factor-like DNA binding activity: evidence that the AT1A receptor activates transcription factor-Stat91 and/or a related protein

1994

Journal Article

A Novel Inhibitory Role for Glucocorticoids in the Secretion of Angiotensinogen by C6 Glioma-Cells

Sernia, C and Thomas, WG (1994). A Novel Inhibitory Role for Glucocorticoids in the Secretion of Angiotensinogen by C6 Glioma-Cells. Journal of Neurochemistry, 62 (4), 1296-1301. doi: 10.1046/j.1471-4159.1994.62041296.x

A Novel Inhibitory Role for Glucocorticoids in the Secretion of Angiotensinogen by C6 Glioma-Cells

Current funding

  • 2023 - 2025
    Studying the basis of and developing new therapies to treat heart disease
    IPF Healthy - Medical Research
    Open grant
  • 2023 - 2025
    Protecting hearts from trastuzumab-induced cardiomyopathy
    NHMRC IDEAS Grants
    Open grant

Past funding

  • 2022 - 2024
    Targeting cavin-1 via gene therapy in a model of metabolic/low-level chronic stress
    Diabetes Australia Research Program
    Open grant
  • 2020 - 2023
    Understanding how an old heart gets stiff
    ARC Discovery Projects
    Open grant
  • 2019 - 2022
    How tissues generate the peptide hormone angiotensin II
    ARC Discovery Projects
    Open grant
  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2018
    A potential role for C5a antagonism in the medical management of feline hypertrophic cardiornyopathy
    Peter & Mary Ellen Stone Memorial Fund
    Open grant
  • 2017 - 2018
    A Pharmacology Screening Facility to Accelerate Drug Discovery and Development
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    A state-of-the-art spinning disc confocal microscope for high speed imaging of live cells and super resolution microscopy
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2017
    New mediators of GPCR-growth factor receptor transactivation
    NHMRC Project Grant
    Open grant
  • 2015 - 2017
    PIPS regulate the type 1 angiotensin receptor (NHMRC Project Grant administered by Monash University)
    Monash University
    Open grant
  • 2014 - 2016
    Dietary Na reduction, food hedonism and hypertension
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant
  • 2014
    Establishment of a small animal surgical suite for integrative physiology.
    Open grant
  • 2014
    Mitochondrial analysis suite
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2015
    Chemosensory receptors in heart
    National Heart Foundation of Australia
    Open grant
  • 2013
    Establishment of an Integrated Facility for Single Cell Analysis
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    Establishment of Integrated Small Animal Metabolic and Physiology Assessment Facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012
    Examining vascular structure and function using pressurised myography
    NHMRC Equipment Grant
    Open grant
  • 2012 - 2016
    Manipulating store-operated Ca2+ entry to improve muscle function in dystrophy
    NHMRC Project Grant
    Open grant
  • 2012 - 2014
    Mechanism of Epidermal Growth Factor Receptor Transactivation
    NHMRC Project Grant
    Open grant
  • 2011
    A Multi-Channel Fluorescence Plate Reader for Studying Receptor-Ligand Interactions
    NHMRC Equipment Grant
    Open grant
  • 2011 - 2013
    Role of extracellular surface residues in agonist activation of the alpha1 adrenoceptor
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Improving muscle function in dystrophy
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2010
    Dual channel electrophysiological recordings
    NHMRC Equipment Grant
    Open grant
  • 2010
    High content imaging analysis for bioactive and novel therapeutic target evaluation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2012
    Molecular regulation of angiotensin receptors
    NHMRC Project Grant
    Open grant
  • 2010 - 2012
    Unravelling the sub-nuclear complexity of the brain (ARC Discovery Project administered by the University of Melbourne)
    University of Melbourne
    Open grant
  • 2009
    "Real Time PCR Facility for Biomedical Researchers"
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Establishment of a rodent cardiovascular and metabolic phenotyping platform
    UQ School/Centre Co-Funding
    Open grant
  • 2009
    Liquid Scintillation Spectroscopy Facility
    UQ School/Centre Co-Funding
    Open grant
  • 2008 - 2010
    NHMRC Senior Research Fellowship B
    NHMRC Research Fellowship
    Open grant
  • 2008 - 2010
    EGFR transactivation in cardiac hypertrophy
    NHMRC Project Grant
    Open grant
  • 2008 - 2009
    Molecular regulation of the type 1 angiotensin receptor
    NHMRC Project Grant
    Open grant
  • 2008 - 2010
    Regulation of Cardiac Hypertrophy (NHMRC grant administered by the University of Melbourne)
    Peter MacCallum Cancer Centre
    Open grant
  • 2008
    Understanding cell physiology by confocal laser scanning microscopy
    UQ Major Equipment and Infrastructure
    Open grant

Availability

Professor Wally Thomas is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Epidermal growth factor receptors in cardiac function and disease

    Principal Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    The role of neuregulin in cardiac function and failure

    Principal Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.

    Associate Advisor

    Other advisors: Associate Professor Dominic Ng, Dr Melissa Reichelt

  • Doctor Philosophy

    Understanding the role of HER2 in cardiac function.

    Associate Advisor

    Other advisors: Professor Fiona Simpson, Dr Melissa Reichelt

  • Doctor Philosophy

    Deciphering the Role of Immune Signalling in Cardiac Dysfunction

    Associate Advisor

  • Doctor Philosophy

    Understanding the role of WD40-Repeat Protein 62 (WDR62) in the regulation of heart function.

    Associate Advisor

    Other advisors: Associate Professor Dominic Ng, Dr Melissa Reichelt

  • Doctor Philosophy

    Understanding cardiomyocyte-endothelial cell interactions in regulating cardiac function

    Associate Advisor

    Other advisors: Dr Melissa Reichelt

  • Doctor Philosophy

    The role of C5a and ß-1 adrenergic receptors on cardiovascular function in cats

    Associate Advisor

    Other advisors: Professor Trent Woodruff, Professor Paul Mills

  • Doctor Philosophy

    Understanding cardiomyocyte-endothelial cell interactions in regulating cardiac function

    Associate Advisor

    Other advisors: Dr Melissa Reichelt

Completed supervision

Enquiries

Contact Professor Wally Thomas directly for media enquiries about:

  • Cardiovascular disease
  • Cardiovascular system
  • Cell biology
  • Cell signalling
  • G protein-coupled receptors
  • Heart disease

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