Dr Christopher Howard
Dr

Christopher Howard

Email: 
Phone: 
+61 7 334 64209

Availability

Dr Christopher Howard is:
Available for supervision

Qualifications

  • Doctor of Philosophy, Queensland University of Technology

Research interests

  • Protein engineering, Programmable Bionanomaterials, Molecular Discovery, Bio Nano Technologies

Search Professor Christopher Howard’s works on UQ eSpace

81 works between 2005 and 2025
All (81) Journal Article (77) Conference Publication (4)

61 - 80 of 81 works

2018

Journal Article

Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant

Pham, Huong Thi, Nhiep, Nguyen Thi Hanh, Vu, Thu Ngoc Minh, Huynh, TuAnh Ngoc, Zhu, Yan, Huynh, Anh Le Diep, Chakrabortti, Alolika, Marcellin, Esteban, Lo, Raquel, Howard, Christopher B., Bansal, Nidhi, Woodward, Joshua J., Liang, Zhao-Xun and Turner, Mark S. (2018). Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant. PLOS Genetics, 14 (8) e1007574, e1007574. doi: 10.1371/journal.pgen.1007574

Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant

2018

Journal Article

Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach

Fontaine, Frank R., Goodall, Stephen, Prokop, Jeremy W., Howard, Christopher B., Moustaqil, Mehdi, Kumble, Sumukh, Rasicci, Daniel T., Osborne, Geoffrey W., Gambin, Yann, Sierecki, Emma, Jones, Martina L., Zuegg, Johannes, Mahler, Stephen and Francois, Mathias (2018). Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach. mAbs, 10 (4), 1-11. doi: 10.1080/19420862.2018.1451288

Functional domain analysis of SOX18 transcription factor using a single-chain variable fragment-based approach

2018

Journal Article

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

Tang, Jie, Howard, Christopher B., Mahler, Stephen M., Thurecht, Kristofer J., Huang, Leaf and Xu, Zhi Ping (2018). Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands. Nanoscale, 10 (9), 4258-4266. doi: 10.1039/c7nr08644j

Enhanced delivery of siRNA to triple negative breast cancer cells in vitro and in vivo through functionalizing lipid-coated calcium phosphate nanoparticles with dual target ligands

2018

Journal Article

Bispecific antibody-functionalized upconversion nanoprobe

He, Hao, Howard, Christopher B., Chen, Yinghui, Wen, Shihui, Lin, Gungun, Zhou, Jiajia, Thurecht, Kristofer J. and Jin, Dayong (2018). Bispecific antibody-functionalized upconversion nanoprobe. Analytical Chemistry, 90 (5), 3024-3029. doi: 10.1021/acs.analchem.7b05341

Bispecific antibody-functionalized upconversion nanoprobe

2018

Journal Article

Recent advances in the generation of antibody-nanomaterial conjugates

Sivaram, Amal J, Wardiana, Andri, Howard, Christopher B, Mahler, Stephen M and Thurecht, Kristofer J (2018). Recent advances in the generation of antibody-nanomaterial conjugates. Advanced Healthcare Materials, 7 (1) 1700607. doi: 10.1002/adhm.201700607

Recent advances in the generation of antibody-nanomaterial conjugates

2017

Journal Article

Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models

Alfaleh, Mohamed A., Howard, Christopher B., Sedliarou, Ilya, Jones, Martina L., Gudhka, Reema, Vanegas, Natasha, Weiss, Jocelyn, Suurbach, Julia H., de Bakker, Christopher J., Milne, Michael R., Rumballe, Bree A., MacDiarmid, Jennifer A., Brahmbhatt, Himanshu and Mahler, Stephen M. (2017). Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models. Plos One, 12 (10) e0186137, e0186137. doi: 10.1371/journal.pone.0186137

Targeting mesothelin receptors with drug-loaded bacterial nanocells suppresses human mesothelioma tumour growth in mouse xenograft models

2017

Journal Article

Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing

Wuethrich, Alain, Howard, Christopher B. and Trau, Matt (2017). Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing. Microchemical Journal, 137, 231-237. doi: 10.1016/j.microc.2017.10.012

Geometric optimisation of electrohydrodynamic fluid flows for enhanced biosensing

2017

Journal Article

Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsions

Tayeb, Hossam H, Piantavigna, Stefania, Howard, Christopher B, Nouwens, Amanda, Mahler, Stephen M, Middelberg, Anton P J, He, Lizhong, Holt, Stephen A and Sainsbury, Frank (2017). Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsions. Soft matter, 13 (43), 7953-7961. doi: 10.1039/c7sm01614j

Insights into the interfacial structure-function of poly(ethylene glycol)-decorated peptide-stabilised nanoscale emulsions

2017

Journal Article

Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning

Alfaleh, Mohamed A., Jones, Martina L., Howard, Christopher B. and Mahler, Stephen M. (2017). Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning. Antibodies, 6 (3) 10, 1-19. doi: 10.3390/antib6030010

Strategies for Selecting Membrane Protein-Specific Antibodies using Phage Display with Cell-Based Panning

2016

Journal Article

Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10

Alsultan, Abdulkarim M., Chin, David Y., Howard, Christopher B., de Bakker, Christopher J., Jones, Martina L. and Mahler, Stephen M. (2016). Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10. Scientific Reports, 5 (37348) 37348, 37348. doi: 10.1038/srep37348

Beyond antibodies: development of a novel protein scaffold based on human chaperonin 10

2016

Journal Article

Biosimilars approved for treatment of inflammatory rheumatological diseases

Mahler, Stephen M., Wardiana, Andri, Jones, Martina L., De Bakker, Christopher J., Graham, Garry G. and Howard, Christopher B. (2016). Biosimilars approved for treatment of inflammatory rheumatological diseases. International Journal of Rheumatic Diseases, 19 (11), 1043-1048. doi: 10.1111/1756-185X.13037

Biosimilars approved for treatment of inflammatory rheumatological diseases

2016

Journal Article

Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies

Howard, Christopher B., Fletcher, Nicholas, Houston, Zachary H., Fuchs, Adrian V., Boase, Nathan R. B., Simpson, Joshua D., Raftery, Lyndon J., Ruder, Tim, Jones, Martina L., de Bakker, Christopher J., Mahler, Stephen M. and Thurecht, Kristofer J. (2016). Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies. Advanced Healthcare Materials, 5 (16), 2055-2068. doi: 10.1002/adhm.201600263

Overcoming Instability of Antibody-Nanomaterial Conjugates: Next Generation Targeted Nanomedicines Using Bispecific Antibodies

2016

Journal Article

Targeting membrane proteins for antibody discovery using phage display

Jones, Martina L., Alfaleh, Mohamed A., Kumble, Sumukh, Zhang, Shuo, Osborne, Geoffrey W., Yeh, Michael, Arora, Neetika, Hou, Jeff Jia Cheng, Howard, Christopher B., Chin, David Y. and Mahler, Stephen M. (2016). Targeting membrane proteins for antibody discovery using phage display. Scientific Reports, 6 (1) 26240, 26240. doi: 10.1038/srep26240

Targeting membrane proteins for antibody discovery using phage display

2016

Journal Article

Biosensing made easy with PEG-targeted bi-specific antibodies

Raftery, Lyndon J., Grewal, Yadveer S., Howard, Christopher B., Jones, Martina L., Shiddiky, Muhammad J. A., Carrascosa, Laura G., Thurecht, Kristofer J., Mahler, Stephen M. and Trau, Matt (2016). Biosensing made easy with PEG-targeted bi-specific antibodies. Chemical Communications, 52 (33), 5730-5733. doi: 10.1039/C6CC01916A

Biosensing made easy with PEG-targeted bi-specific antibodies

2015

Journal Article

Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells

Tang, Jie, Li, Li, Howard, Christopher B., Mahler, Stephen M., Huang, Leaf and Xu, Zhi Ping (2015). Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells. Journal of Materials Chemistry B, 3 (33), 6805-6812. doi: 10.1039/c5tb00912j

Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells

2015

Journal Article

Production and characterisation of recombinant human chaperonin 10 for treatment of inflammatory disease

Naylor, Dean J., Hunt, Ben, Guidolin, Angelo, Hey, Allan W., Bastiras, Stan, de Bakker, Christopher J., Chin, David Y., Marquis, Christopher P., Lambert, Daniel, Howard, Christopher B., Dobbin, Caroline A. and Mahler, Stephen M. (2015). Production and characterisation of recombinant human chaperonin 10 for treatment of inflammatory disease. Process Biochemistry, 50 (10) 10466, 1669-1679. doi: 10.1016/j.procbio.2015.06.022

Production and characterisation of recombinant human chaperonin 10 for treatment of inflammatory disease

2014

Journal Article

Nanocell targeting using engineered bispecific antibodies.

Taylor, Karin, Howard, Christopher B., Jones, Martina L., Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P. and Mahler, Stephen M. (2014). Nanocell targeting using engineered bispecific antibodies.. mAbs, 7 (1), 53-65. doi: 10.4161/19420862.2014.985952

Nanocell targeting using engineered bispecific antibodies.

2014

Journal Article

Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells

Buecheler, Jakob W., Howard, Christopher B., de Bakker, Christopher J., Goodall, Stephen, Jones, Martina L, Win, Thinzar, Peng, Tao, Tan, Cher Heng, Chopra, Akhil, Mahler, Stephen M and Lim, Sierin (2014). Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells. Journal of Chemical Technology and Biotechnology, 90 (7), 1230-1236. doi: 10.1002/jctb.4545

Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells

2014

Journal Article

An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer

Goodall, Stephen, Howard, Christopher B., Jones, Martina L., Munro,Trent, Jia, Zhongfan, Monteiro, Michael J and Mahler, Stephen (2014). An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer. Journal of Chemical Technology and Biotechnology, 90 (7), 1222-1229. doi: 10.1002/jctb.4509

An EGFR targeting nanoparticle self assembled from a thermoresponsive polymer

2012

Journal Article

Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP

Mo, Jinyao, Boyle, Joseph P., Howard, Christopher B., Monie, Tom P., Davis, Beckley K. and Duncan, Joseph A. (2012). Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP. Journal of Biological Chemistry, 287 (27), 23057-23067. doi: 10.1074/jbc.M112.344283

Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP

Current funding

  • 2025 - 2027
    "COVID & Beyond": Innovative rapid response nanoprobes to detect the next pandemic threat.
    NHMRC IDEAS Grants
    Open grant
  • 2023 - 2025
    Research and Development of Membrane Technology
    Aegros Biopharma Pty Ltd
    Open grant

Past funding

  • 2022 - 2025
    An integrated nano-bioengineered chip for enhanced molecular evolution
    ARC Discovery Projects
    Open grant
  • 2021 - 2024
    Innovative delivery methods for the biologic soluble RAGE to prevent Type 1 Diabetes
    JDRF Pilot and Innovation Awards
    Open grant
  • 2020 - 2023
    Novel Virus Trap Nanotechnology for COVID-19 Detection
    Advance Queensland Industry Research Fellowships
    Open grant
  • 2019 - 2022
    Smart affinity membranes for manufacture of high value therapeutic proteins
    ARC Linkage Projects
    Open grant
  • 2019 - 2020
    Evaluation of recombinant biologics for immune modulation
    Servatus Biopharmaceuticals
    Open grant
  • 2019
    Production and analysis of recombinant therapeutics for immune modulation
    Servatus Biopharmaceuticals
    Open grant
  • 2019
    Expression of recombinant proteins in mammalian cells
    Servatus Biopharmaceuticals
    Open grant
  • 2018
    Continuous chromatography system for advanced bioprocessing
    UQ Major Equipment and Infrastructure
    Open grant
  • 2017 - 2018
    Provision of research services to Minomic International Ltd
    Minomic International Ltd
    Open grant
  • 2017 - 2023
    ARC Training Centre for Biopharmaceutical Innovation
    ARC Industrial Transformation Training Centres
    Open grant
  • 2016 - 2017
    EGFR targeted nanoparticle feasibility study
    Samyang Biopharmaceuticals Corporation
    Open grant
  • 2016 - 2019
    Next generation hybrid nanomaterials: bispecific antibody-targeted polymers
    ARC Linkage Projects
    Open grant
  • 2016 - 2018
    Immuno-polymeric drugs for prostate cancer therapy
    NHMRC Project Grant
    Open grant

Availability

Dr Christopher Howard is:
Available for supervision

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Available projects

Supervision history

Current supervision

  • Doctor Philosophy

    Engineering synthetic regulatory circuits for precise metabolic control in Saccharomyces cerevisiae

    Principal Advisor

    Other advisors: Professor Gary Schenk

  • Doctor Philosophy

    Engineering synthetic regulatory circuits for precise metabolic control in Saccharomyces cerevisiae

    Principal Advisor

    Other advisors: Professor Gary Schenk

  • Doctor Philosophy

    Development of next-generation molecular tools for diagnostics

    Principal Advisor

    Other advisors: Professor Matt Trau

  • Doctor Philosophy

    Surface engineering of nanoyeast

    Principal Advisor

    Other advisors: Professor Matt Trau

  • Doctor Philosophy

    Development of next-generation molecular tools for diagnostics

    Principal Advisor

    Other advisors: Professor Matt Trau

  • Doctor Philosophy

    Towards n-plex quantification of molecular interactions for evolution-free biopanning

    Associate Advisor

    Other advisors: Professor Matt Trau

  • Doctor Philosophy

    An integrated nano-bioengineered chip for enhanced molecular evolution

    Associate Advisor

    Other advisors: Professor Matt Trau

  • Doctor Philosophy

    Integration of innovative diagnostic technologies for the detection of flaviviral infections

    Associate Advisor

    Other advisors: Associate Professor Jody Peters

  • Doctor Philosophy

    Integration of innovative platform technologies for the diagnosis of flaviviral infections

    Associate Advisor

    Other advisors: Associate Professor Jody Peters

  • Doctor Philosophy

    Engineering Novel Theranostics for High Grade Glioma Through Site-Specific EphA2 Antibody Modification

    Associate Advisor

    Other advisors: Emeritus Professor Stephen Mahler, Dr Martina Jones

  • Doctor Philosophy

    Engineering Novel Theranostics for High Grade Glioma Through Site-Specific EphA2 Antibody Modification

    Associate Advisor

    Other advisors: Emeritus Professor Stephen Mahler, Dr Martina Jones

  • Doctor Philosophy

    Towards n-plex quantification of molecular interactions for evolution-free biopanning

    Associate Advisor

    Other advisors: Professor Matt Trau

  • Doctor Philosophy

    mRNA cancer therapies

    Associate Advisor

    Other advisors: Professor Timothy Mercer, Associate Professor Seth Cheetham

  • Doctor Philosophy

    Towards n-plex quantification of molecular interactions for evolution-free biopanning

    Associate Advisor

    Other advisors: Professor Matt Trau

  • Doctor Philosophy

    Investigating therapeutic potentials of brain-derived exosomes

    Associate Advisor

    Other advisors: Professor Matt Trau, Dr Richard Lobb

Completed supervision

Enquiries

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