
Overview
Availability
- Professor Luke Guddat is:
- Available for supervision
Fields of research
Works
Search Professor Luke Guddat’s works on UQ eSpace
2000
Journal Article
The three-dimensional structure of a complex of a murine Fab (NC10.14) with a potent sweetener (NC174): An illustration of structural diversity in antigen recognition by immunoglobulins
Guddat, Luke W., Shan, Lin, Broomell, Christopher, Ramsland, Paul A., Fan, Zhao-Chang, Anchin, Jerry M., Linthicum, D. Scott and Edmundson, Allen B. (2000). The three-dimensional structure of a complex of a murine Fab (NC10.14) with a potent sweetener (NC174): An illustration of structural diversity in antigen recognition by immunoglobulins. Journal of Molecular Biology, 302 (4), 853-872. doi: 10.1006/jmbi.2000.4083
2000
Conference Publication
Sweet potato purple acid phosphatase: first example of a strongly antiferromagnetically coupled Fe-Mn binuclear centre in a protein
Schenk, G., Boutchard, C., Noble, C. J., Moubaraki, B., Murray, K. S., Hanson, G. R., De Jersey, J., Hamilton, S. E., Guddat, L. W. and Carrington, L. (2000). Sweet potato purple acid phosphatase: first example of a strongly antiferromagnetically coupled Fe-Mn binuclear centre in a protein. EUROBIC-5, Toulouse, France, 17-20 July 2000.
2000
Journal Article
Identification of mammalian-like purple acid phosphatases in a wide range of plants
Schenk, G., Ge, Y., Guddat, L., Carrington, L. E., Hume, D. A., Hamilton, S. E. and deJersey, J. (2000). Identification of mammalian-like purple acid phosphatases in a wide range of plants. Gene, 250 (1-2), 117-125. doi: 10.1016/S0378-1119(00)00186-4
1999
Journal Article
Crystallization and preliminary X-ray diffraction data for a purple acid phosphastase from sweet potato
Schenk, G., Carrington, L., Hamilton, S. E., De Jersey, J. and Guddat, L. W. (1999). Crystallization and preliminary X-ray diffraction data for a purple acid phosphastase from sweet potato. Acta Crystallographica Section D: Biological Crystallography, 55 (12), 2051-2052. doi: 10.1107/S0907444999012597
1999
Conference Publication
Plasmodium Falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase as a chemotherapeutic target: Comparison of the human and parasite enzymes
Dulley, G., Ng, A., Qi, J., Guddat, L. W., Keough, D. T. and De Jersey, J. (1999). Plasmodium Falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase as a chemotherapeutic target: Comparison of the human and parasite enzymes. ComBio 99, Conrad Jupiter, Gold Coast, 27-30 September, 1999. Kent Town, SA: Australian Society for Biochemistry and Molecular Biology.
1999
Journal Article
Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-γ-interferon antibody
Fan, Zhao-Chang, Shan, Lin, Goldsteen, Benjamin Z., Guddat, Luke W., Thakur, Archana, Landolfi, Nicholas F., Co, Man Sung, Vasquez, Maximiliano, Queen, Cary, Ramsland, Paul A. and Edmundson, Allen B. (1999). Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-γ-interferon antibody. Journal of Molecular Recognition, 12 (1), 19-32. doi: 10.1002/(SICI)1099-1352(199901/02)12:13.0.CO;2-Y
1999
Conference Publication
Planrtpurple acid phosphatases: Novel forms of the enzyme
Schenk, G., Carrington, L., Guddat, L. W., De Jersey, J. and Hamilton, S. E. (1999). Planrtpurple acid phosphatases: Novel forms of the enzyme. ComBio 99, Conrad Jupiters, Gold Coast, 27-30 September, 1999. Kent Town, SA: Aust. Society for Biochemistry and Molecular Biology.
1999
Journal Article
Crystallization and preliminary X-ray diffraction studies of mammalian purple acid phosphatase
Guddat, L. W., McAlpine, A. S., Hume, D. A., De Jersey, J., Hamilton, S. E. and Martin, J. L. (1999). Crystallization and preliminary X-ray diffraction studies of mammalian purple acid phosphatase. Acta Crystallographica Section D: Biological Crystallography, 55 (8), 1462-1464. doi: 10.1107/S0907444999006241
1999
Conference Publication
Crystal structure of mammalian purple acid phosphatase: An enzyme with a binuclear metal centre
Guddat, L. W., McAlpine, A. S., Hume, D. A., Hamilton, S. E, De Jersey, J. and Martin, J. L. (1999). Crystal structure of mammalian purple acid phosphatase: An enzyme with a binuclear metal centre. ComBio 99, Conrad Jupiters, Gold Coast, 27-30 September, 1999. Kent Town, SA: Aust. Society for Biochemistry & Molecular Biology.
1999
Journal Article
Crystal structure of mammalian purple acid phosphatase
Guddat, L. W., McAlpine, A. S., Hume, D. A., Hamilton, S. E., De Jersey, J. and Martin, J. L. (1999). Crystal structure of mammalian purple acid phosphatase. Structure With Folding & Design, 7 (7), 757-767. doi: 10.1016/S0969-2126(99)80100-2
1999
Conference Publication
Crystallisation of a mammalian purple acid phosphatase
Hamilton, S. E., Guddat, L. W., McAlpine, A. S., Hume, D. A., De Jersey, J. and Martin, J. L. (1999). Crystallisation of a mammalian purple acid phosphatase. 24th Annual Lorne Conference on Protein Structure and Functin, Erskine House, Lorne, Vic., 7-11 February, 1999. Lorne: Lorne Aust..
1998
Journal Article
Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization
Guddat, LW, Bardwell, JCA and Martin, JL (1998). Crystal structures of reduced and oxidized DsbA: investigation of domain motion and thiolate stabilization. Structure, 6 (6), 757-767. doi: 10.1016/S0969-2126(98)00077-X
1998
Journal Article
Three-dimensional structure of a human Fab with high affinity for tetanus toxoid
Faber, Catherine, Shan, Lin, Fan, Zhao-Chang, Guddat, Luke W., Furebring, Christina, Ohlin, Mats, Borrebaeck, Carl A.K. and Edmundson, Allen B. (1998). Three-dimensional structure of a human Fab with high affinity for tetanus toxoid. Immunotechnology, 3 (4), 253-270. doi: 10.1016/S1380-2933(97)10003-3
1997
Journal Article
Structural analysis of three His32 mutants of DsbA: Support for an electrostatic role of His32 in DsbA stability
Guddat, LW, Bardwell, JCA, Glockshuber, R, HuberWunderlich, M, Zander, T and Martin, JL (1997). Structural analysis of three His32 mutants of DsbA: Support for an electrostatic role of His32 in DsbA stability. Protein Science, 6 (9), 1893-1900. doi: 10.1002/pro.5560060910
1997
Journal Article
The uncharged surface features surrounding the active site of Escherichia coli DsbA are conserved and are implicated in peptide binding
Guddat, LW, Bardwell, JCA, Zander, T and Martin, JL (1997). The uncharged surface features surrounding the active site of Escherichia coli DsbA are conserved and are implicated in peptide binding. Protein Science, 6 (6), 1148-1156. doi: 10.1002/pro.5560060603
1997
Book Chapter
Structure of DsbA
Guddat, Luke and Martin, Jennifer Louise (1997). Structure of DsbA. Guidebook to molecular chaperones and protein-folding catalysts. (pp. x-xx) Oxford (U.K.): Oxford Universit Press.
1996
Journal Article
Three-dimensional structure of the alpha-conotoxin GI at 1.2 angstrom resolution
Guddat, LW, Martin, JL, Shan, L, Edmundson, AB and Gray, WR (1996). Three-dimensional structure of the alpha-conotoxin GI at 1.2 angstrom resolution. Biochemistry, 35 (35), 11329-11335. doi: 10.1021/bi960820h
1996
Journal Article
The 1.1 angstrom crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus
Hu, Shu-Hong, Gehrmann, John, Guddat, Luke W., Alewood, Paul F., Craik, David J. and Martin, Jennifer L. (1996). The 1.1 angstrom crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus. Structure, 4 (4), 417-423. doi: 10.1016/S0969-2126(96)00047-0
1996
Journal Article
Crystallographic analysis of antigen-antibody complexes: End-on insertion of ligands in antibodies - CDR3 loops as arbiters
Edmundson, Allen B., Shan, Lin, Fan, Zhao-Chang, Guddat, Luke W., Hanson, B. Leif and Andersen, Kim N. (1996). Crystallographic analysis of antigen-antibody complexes: End-on insertion of ligands in antibodies - CDR3 loops as arbiters. Methods: A Companion to Methods in Enzymology, 9 (3), 542-558. doi: 10.1006/meth.1996.0062
1995
Journal Article
Intramolecular signaling upon complexation
Guddat, L. W., Shan, L., Fan, Z. C., Andersen, K. N., Linthicum, , Rosauer, R., Linthicum, D. S. and Edmundson, A. B. (1995). Intramolecular signaling upon complexation. FASEB Journal, 9 (1), 101-106.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Luke Guddat is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Developing next generation green herbicides
Principal Advisor
Other advisors: Professor Craig Williams
-
-
Doctor Philosophy
Cryo-EM inspired antifungal drug discovery
Principal Advisor
Other advisors: Professor Gary Schenk, Professor Craig Williams
-
Doctor Philosophy
Cryo-EM inspired antifungal drug discovery
Principal Advisor
Other advisors: Professor Gary Schenk, Professor Craig Williams
-
Doctor Philosophy
Acetohydroxyacid Synthase and The Discovery of Novel Herbicides
Principal Advisor
Other advisors: Professor Gary Schenk
-
Doctor Philosophy
Acetohydroxyacid Synthase and The Discovery of Novel Herbicides
Principal Advisor
Other advisors: Professor Gary Schenk
-
-
Doctor Philosophy
Antimicrobial Drug Discovery
Principal Advisor
Other advisors: Professor Gary Schenk
-
Doctor Philosophy
Discovery of New Herbicides
Associate Advisor
Other advisors: Professor Craig Williams
Completed supervision
-
2025
Doctor Philosophy
Acetohydroxyacid Synthase and The Discovery of Novel Herbicides
Principal Advisor
Other advisors: Professor Gary Schenk
-
2024
Doctor Philosophy
Structure and function of ketol-acid reductoisomerases
Principal Advisor
Other advisors: Professor Gary Schenk
-
2024
Doctor Philosophy
Drug discovery targeting branched chain amino acid biosynthesis.
Principal Advisor
Other advisors: Professor Gary Schenk
-
2023
Doctor Philosophy
New Antimicrobial Drug Targets
Principal Advisor
Other advisors: Professor Nick West
-
2021
Doctor Philosophy
Structure and function of plant and fungal acetohydroxyacid synthases
Principal Advisor
Other advisors: Professor James Fraser
-
2021
Doctor Philosophy
Ketol-acid Reductoisomerase as a target for antimicrobial drug discovery
Principal Advisor
Other advisors: Professor Gary Schenk
-
2018
Doctor Philosophy
Structure, mechanism and inhibition of plant and fungal acetohydroxyacid synthases
Principal Advisor
Other advisors: Professor Gary Schenk
-
2017
Doctor Philosophy
Acyclic nucleoside phosphonates as possible chemotherapeutic agents against parasitic diseases
Principal Advisor
-
2017
Doctor Philosophy
Bacterial ketol-acid reductoisomerase: structure, catalytic mechanism and thermal stability
Principal Advisor
Other advisors: Professor Bostjan Kobe, Professor Mark Schembri
-
2017
Doctor Philosophy
Targeting acetohydroxyacid synthase for the discovery of antifungal and herbicidal agents
Principal Advisor
Other advisors: Professor Gary Schenk
-
2016
Doctor Philosophy
Inhibition of Bacterial 6-Oxopurine Phosphoribosyltransferase as Potential Antibacterial Target
Principal Advisor
Other advisors: Professor Nick West
-
2014
Doctor Philosophy
A study of the anticoagulant mechanisms of three biological compounds in vitro and in vivo
Principal Advisor
-
2013
Master Philosophy
Functional studies of rice KARI and inhibitor discovery
Principal Advisor
Other advisors: Professor Gary Schenk
-
-
2023
Doctor Philosophy
Structure, function and inhibition of Fe-S cluster-dependent dehydratases from the ilvD/EDD family
Associate Advisor
Other advisors: Professor Mikael Boden, Professor Gary Schenk
-
2022
Doctor Philosophy
Design, Synthesis, and Evaluation of Ketol-Acid Reductoisomerase Inhibitors: Potential Anti-Tuberculosis Drug Leads
Associate Advisor
Other advisors: Professor Gary Schenk
-
2021
Doctor Philosophy
Binuclear Metallohydrolases: Diversity in Structure and Function
Associate Advisor
Other advisors: Professor Gary Schenk
-
2021
Doctor Philosophy
Engineering stable cytochrome P450 2D forms as competent biocatalysts for industrial applications
Associate Advisor
Other advisors: Professor Elizabeth Gillam
-
2021
Doctor Philosophy
Structural and functional characterisation of ancestral cytochromes P450 from family 2 in tetrapods
Associate Advisor
Other advisors: Professor Elizabeth Gillam
-
2019
Doctor Philosophy
Acetohydroxyacid synthase AHAS: A new drug target for human fungal pathogens
Associate Advisor
Other advisors: Professor Craig Williams
-
2019
Doctor Philosophy
Drug Discovery Using Rational Structure-Based Design Approaches
Associate Advisor
Other advisors: Professor Gary Schenk
-
2012
Doctor Philosophy
IMPROVING OUTCOMES OF BIOCHEMICAL TESTING IN THE PATHOLOGY LABORATORY
Associate Advisor
-
2010
Doctor Philosophy
Characterisation of the first bacterial purple acid phosphates from Mycobacterium marinum
Associate Advisor
Other advisors: Professor Gary Schenk
-
2005
Doctor Philosophy
CRYSTAL STRUCTURE DETERMINATION AND SITE-DIRECTED MUTAGENESIS OF ACTIVE SITE RESIDUES IN ESCHERICHIA COLI KETOL-ACID REDUCTOISOMERASE
Associate Advisor
Media
Enquiries
For media enquiries about Professor Luke Guddat's areas of expertise, story ideas and help finding experts, contact our Media team: