Overview
Background
Critical Care Medicine focuses on supporting patients, often with one or multiple organ failures. Based at the largest Australian cardiac hospital, our research investigates better ways to support patients with heart and/or lung failure. We explore technological, pharmacological and engineering advances that could help our patients to live longer and better. Our group is world-renowned for clinically relevant large animal models, including heart failure, respiratory failure (ARDS), heart transplantation, sepsis, cardiogenic shock, and more. All our studies use hospital-grade equipment and follow the same clinical guideline to maximise translation. We actively take on honours, MPhil and PhD students from multi-disciplinary backgrounds (science, engineering, medicine, allied health), with a successful track record in supporting our students to secure their own grants and funding. Students are expected to contribute to other studies of the group. For more information about the group, please visit ccrg.org.au, and email if you are interested to join us.
Availability
- Associate Professor Jacky Suen is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy of Pharmacology, The University of Queensland
- Member, Extracorporeal Life Support Organization, Extracorporeal Life Support Organization
Works
Search Professor Jacky Suen’s works on UQ eSpace
2024
Journal Article
Protocol for high-plex, whole-slide imaging of human formalin-fixed paraffin-embedded tissue using PhenoCycler-Fusion
Donovan, Meg L., Jhaveri, Niyati, Ma, Ning, Cheikh, Bassem Ben, DeRosa, James, Mihani, Ritu, Berrell, Naomi, Suen, Jacky Y., Monkman, James, Fraser, John F. and Kulasinghe, Arutha (2024). Protocol for high-plex, whole-slide imaging of human formalin-fixed paraffin-embedded tissue using PhenoCycler-Fusion. STAR Protocols, 5 (3) 103226, 1-18. doi: 10.1016/j.xpro.2024.103226
2024
Conference Publication
In vivo isolated lung perfusion: an innovative platform for assessing lung injury propagation in ARDS
Fior, Gabriele, Lloyd, Benjamin, Liu, Keibun, Milani, Angelo, Obonyo, Nchafatso, Hoshino, Kota, Nonaka, Hideaki, Abbate, Gabriella, Portatadino, Sofia, Panduru, Rachana, Hyslop, Kieran, Passmore, Margaret, Meechan-Brown, Carolyn, Redmond, Kendal, Slaughter, Richard, Garlick, Bruce, Mcgiffin, David, Suen, Jacky, Fraser, John and Li Bassi, Gianluigi (2024). In vivo isolated lung perfusion: an innovative platform for assessing lung injury propagation in ARDS. European Respiratory Society Congress (ERS), Vienna, Austria, 7-11 September 2024. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2024.pa845
2024
Conference Publication
Development of Right Ventricular Dysfunction Induced by Respiratory Failure: Insights from an Ovine Model of Acute Respiratory Distress Syndrome and Veno-Venous Extracorporeal Membrane Oxygenation
Nonaka, Hideaki, Liu, Keibun, Milani, Angelo, Fior, Gabriele, Hoshino, Kota, Obonyo, Nchafatso, Portatadino, Sofia, Abbate, Gabriella, Panduru, Rachana, McInerney, Molly-Rose, Passmore, Margaret, Li Bassi, Gianluigi, Suen, Jacky and Fraser, John F. (2024). Development of Right Ventricular Dysfunction Induced by Respiratory Failure: Insights from an Ovine Model of Acute Respiratory Distress Syndrome and Veno-Venous Extracorporeal Membrane Oxygenation. 35th Annual ELSO Conference, Detroit, MI United States, 28 September - 1 October 2024. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1097/01.mat.0001070112.10477.fa
2024
Journal Article
Impact of hemoglobin levels on composite cardiac arrest or stroke outcome in patients with respiratory failure due to COVID-19
Feng, Shi Nan, Kelly, Thu-Lan, Fraser, John F., Li Bassi, Gianluigi, Suen, Jacky, Zaaqoq, Akram, Griffee, Matthew J., Arora, Rakesh C., White, Nicole, Whitman, Glenn, Robba, Chiara, Battaglini, Denise, Cho, Sung-Min, on behalf of COVID-19 Critical Care Consortium (CCCC) and Obonyo, Gikenyi N. (2024). Impact of hemoglobin levels on composite cardiac arrest or stroke outcome in patients with respiratory failure due to COVID-19. Critical Care Explorations, 6 (9) e1143, 1-12. doi: 10.1097/CCE.0000000000001143
2024
Journal Article
Optimising Clinical Epidemiology in Disease Outbreaks: Analysis of ISARIC-WHO COVID-19 Case Report Form Utilisation
Merson, Laura, Duque, Sara, Garcia-Gallo, Esteban, Yeabah, Trokon Omarley, Rylance, Jamie, Diaz, Janet, Flahault, Antoine, Abdalasalam, Sabriya, Abdalhadi, Alaa Abdalfattah, Abdalla, Walaa, Abdalla, Naana Reyam, Abdalrheem, Almthani Hamza, Abdalsalam, Ashraf, Abdeewi, Saedah, Abdelgaum, Esraa Hassan, Abdelhalim, Mohamed, Abdelkabir, Mohammed, Abdukahil, Sheryl Ann, Abdulbaqi, Lamees Adil, Abdulhamid, Widyan, Abdulhamid, Salaheddin, Abdulkadir, Nurul Najmee, Abdulwahed, Eman, Abdunabi, Rawad, Abe, Ryuzo, Abel, Laurent, Abodina, Ahmed Mohammed, Abouelmagd, Khaled, Abrous, Amal ... and ISARIC Clinical Characterisation Group (2024). Optimising Clinical Epidemiology in Disease Outbreaks: Analysis of ISARIC-WHO COVID-19 Case Report Form Utilisation. Epidemiologia, 5 (3), 557-580. doi: 10.3390/epidemiologia5030039
2024
Journal Article
Lightweight transformers for clinical natural language processing
Rohanian, Omid, Nouriborji, Mohammadmahdi, Jauncey, Hannah, Kouchaki, Samaneh, Nooralahzadeh, Farhad, Clifton, Lei, Merson, Laura, Clifton, David A., Abbas, Ali, Abdukahil, Sheryl Ann, Abdulkadir, Nurul Najmee, Abe, Ryuzo, Abel, Laurent, Abrous, Amal, Absil, Lara, Jabal, Kamal Abu, Salah, Nashat Abu, Acharya, Subhash, Acker, Andrew, Adachi, Shingo, Adam, Elisabeth, Adewhajah, Francisca, Adriano, Enrico, Adrião, Diana, Al Ageel, Saleh, Ahmed, Shakeel, Aiello, Marina, Ainscough, Kate, Airlangga, Eka ... Zucman, David (2024). Lightweight transformers for clinical natural language processing. Natural Language Engineering, 30 (5), 887-914. doi: 10.1017/S1351324923000542
2024
Journal Article
Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study
Obonyo, Nchafatso. G., Dhanapathy, Vikash, White, Nicole, Sela, Declan P., Rachakonda, Reema H., Tunbridge, Matthew, Sim, Beatrice, Teo, Derek, Nadeem, Zohaib, See Hoe, Louise E., Bassi, Gianluigi Li, Fanning, Jonathon P., Tung, John-Paul, Suen, Jacky Y. and Fraser, John F. (2024). Effects of red blood cell transfusion on patients undergoing cardiac surgery in Queensland – a retrospective cohort study. Journal of Cardiothoracic Surgery, 19 (1) 475, 1-9. doi: 10.1186/s13019-024-02974-7
2024
Journal Article
Worldwide application and valuation of extracorporeal membrane oxygenation support during the COVID-19 pandemic (WAVES)
Zaaqoq, Akram M, Heinsar, Silver, Yoon, Hwan-Jin, White, Nicole, Griffee, Matthew J, Suen, Jacky Y, Bassi, Gianluigi L, Fanning, Jonathon P, Shehatta, Ahmad Labib, M.A. Alexander, Peta, Jacobs, Jeffrey P., Dalton, Heidi J, Lorusso, Roberto, Cho, Sung-Min, Peek, Giles J, Fraser, John F and COVID-19 Critical Care Consortium (COVID Critical) (2024). Worldwide application and valuation of extracorporeal membrane oxygenation support during the COVID-19 pandemic (WAVES). Perfusion, 40 (4), 993-1003. doi: 10.1177/02676591241267228
2024
Journal Article
Current trends and latest developments in echocardiographic assessment of right ventricular function: load dependency perspective
Nonaka, Hideaki, Rätsep, Indrek, Obonyo, Nchafatso G., Suen, Jacky Y., Fraser, John F. and Chan, Jonathan (2024). Current trends and latest developments in echocardiographic assessment of right ventricular function: load dependency perspective. Frontiers in Cardiovascular Medicine, 11 1365798, 1-15. doi: 10.3389/fcvm.2024.1365798
2024
Journal Article
Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium
Feth, Maximilian, Weaver, Natasha, Fanning, Robert B., Cho, Sung-Min, Griffee, Matthew J., Panigada, Mauro, Zaaqoq, Akram M., Labib, Ahmed, Whitman, Glenn J. R., Arora, Rakesh C., Kim, Bo S., White, Nicole, Suen, Jacky Y., Li Bassi, Gianluigi, Peek, Giles J., Lorusso, Roberto, Dalton, Heidi, Fraser, John F., Fanning, Jonathon P., Bassi, Gianluigi Li, Suen, Jacky Y., Dalton, Heidi J., Laffey, John, Brodie, Daniel, Fan, Eddy, Torres, Antoni, Chiumello, Davide, Elhazmi, Alyaa, Hodgson, Carol ... the COVID-19 Critical Care Consortium (2024). Hemorrhage and thrombosis in COVID-19-patients supported with extracorporeal membrane oxygenation: an international study based on the COVID-19 critical care consortium. Journal of Intensive Care, 12 (1) 18, 1-12. doi: 10.1186/s40560-024-00726-2
2024
Journal Article
Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms
Citarella, Barbara Wanjiru, Kartsonaki, Christiana, Ibáñez-Prada, Elsa D., Gonçalves, Bronner P., Baruch, Joaquin, Escher, Martina, Pritchard, Mark G., Wei, Jia, Philippy, Fred, Dagens, Andrew, Hall, Matthew, Lee, James, Kutsogiannis, Demetrios James, Wils, Evert-Jan, Fernandes, Marília Andreia, Tirupakuzhi Vijayaraghavan, Bharath Kumar, Panda, Prasan Kumar, Martin-Loeches, Ignacio, Ohshimo, Shinichiro, Fatoni, Arie Zainul, Horby, Peter, Dunning, Jake, Rello, Jordi, Merson, Laura, Rojek, Amanda, Vaillant, Michel, Olliaro, Piero, Reyes, Luis Felipe, Moharam, S.A. ... Zucman, David (2024). Characteristics and outcomes of COVID-19 patients admitted to hospital with and without respiratory symptoms. Heliyon, 10 (10) e29591, e29591. doi: 10.1016/j.heliyon.2024.e29591
2024
Journal Article
Comparative analysis of novel esophageal pressure monitoring catheters versus commercially available alternatives in a biomechanical model of the thoracic cavity
Abbate, Gabriella, Colombo, Sebastiano Maria, Semenzin, Clayton, Sato, Noriko, Liu, Keibun, Ainola, Carmen, Milani, Angelo, Fior, Gabriele, Obonyo, Nchafatso, White, Nicole, Chiumello, Davide, Pauls, Jo, Suen, Jacky Y., Fraser, John F. and Li Bassi, Gianluigi (2024). Comparative analysis of novel esophageal pressure monitoring catheters versus commercially available alternatives in a biomechanical model of the thoracic cavity. Scientific Reports, 14 (1) 9771, 1-12. doi: 10.1038/s41598-024-59790-1
2024
Journal Article
Improved microcirculation with pulsatile veno-arterial ECMO: an ovine model of cardiogenic shock
Heinsar, Silver, Sato, Kei, Obonyo, Nchafatso, Farah, Samia M, Bouquet, Mahe, Passmore, Margaret R, Liu, Keibun, Ijunin, Shinichi, Ainola, Carmen, Li Bassi, Gianluigi, Suen, Jacky Y and Fraser, John F. (2024). Improved microcirculation with pulsatile veno-arterial ECMO: an ovine model of cardiogenic shock. American Journal of Respiratory and Critical Care Medicine, 209 (11), 1396-1399. doi: 10.1164/rccm.202402-0419le
2024
Journal Article
Variability of oxygen requirements in critically ill COVID-19 patients
Huth, Samuel F., Rothkopf, Alexander, Smith, Lisa, White, Nicole, Bassi, Gianluigi Li, Suen, Jacky Y. and Fraser, John F. (2024). Variability of oxygen requirements in critically ill COVID-19 patients. Journal of Global Health, 14 05012, 05012. doi: 10.7189/jogh.14.05012
2024
Journal Article
Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after COVID-19 hospitalization: an international multicenter prospective observational study
Cho, Sung-Min, Premraj, Lavienraj, Battaglini, Denise, Fanning, Jonathon Paul, Suen, Jacky (ISARIC Clinical Characterization Group), Bassi, Gianluigi Li, Fraser, John, Robba, Chiara, Griffee, Matthew, Solomon, Tom, Semple, Malcolm G, Baillie, Kenneth, Sigfrid, Louise, Scott, Janet T, Citarella, Barbara Wanjiru, Merson, Laura, Arora, Rakesh C, Whitman, Glenn, Thomson, David, White, Nicole, Abel, Laurent, Abrous, Amal, Jabal, Kamal Abu, Zayyad, Hiba Abu, Tamlihat, Younes Ait, Alameen, Aliya Mohammed, Alessi, Marta, Alex, Beatrice, Alexandre, Kévin ... ISARIC Clinical Characterization Group (2024). Sex differences in post-acute neurological sequelae of SARS-CoV-2 and symptom resolution in adults after COVID-19 hospitalization: an international multicenter prospective observational study. Brain Communications, 6 (2) fcae036, 1-14. doi: 10.1093/braincomms/fcae036
2024
Journal Article
A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload
Sato, Kei, Wildi, Karin, Chan, Jonathan, Palmieri, Chiara, Obonyo, Nchafatso G., Heinsar, Silver, Liu, Keibun, Livingstone, Samantha, Sato, Noriko, Ainola, Carmen, Abbate, Gabriella, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Platts, David G., Suen, Jacky, Bassi, Gianluigi Li and Fraser, John F. (2024). A novel speckle‐tracking echocardiography parameter assessing left ventricular afterload. European Journal of Clinical Investigation, 54 (2) e14106, 1-12. doi: 10.1111/eci.14106
2024
Journal Article
An appraisal of lung computer tomography in very early anti-inflammatory treatment of two different ovine ARDS phenotypes
Wildi, Karin, Colombo, Sebastiano Maria, McGuire, Daniel, Ainola, Carmen, Heinsar, Silver, Sato, Noriko, Sato, Kei, Liu, Keibun, Bouquet, Mahé, Wilson, Emily, Passmore, Margaret, Hyslop, Kieran, Livingstone, Samantha, Di Feliciantonio, Marianna, Strugnell, Wendy, Palmieri, Chiara, Suen, Jacky, Li Bassi, Gianluigi and Fraser, John (2024). An appraisal of lung computer tomography in very early anti-inflammatory treatment of two different ovine ARDS phenotypes. Scientific Reports, 14 (1) 2162, 1-11. doi: 10.1038/s41598-024-52698-w
2023
Journal Article
Race and ethnicity in the COVID-19 Critical Care Consortium: demographics, treatments, and outcomes, an international observational registry study
Griffee, Matthew J., Thomson, David A., Fanning, Jonathon, Rosenberger, Dorothea, Barnett, Adrian, White, Nicole M., Suen, Jacky, Fraser, John F., Li Bassi, Gianluigi, Cho, Sung-Min, Dalton, Heidi J., Laffey, John, Brodie, Daniel, Fan, Eddy, Torres, Antoni, Chiumello, Davide, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Marwali, Eva, Grasselli, Giacomo, Bartlett, Robert, Burrell, Aidan, Elhadi, Muhammed ... Zanella, Alberto (2023). Race and ethnicity in the COVID-19 Critical Care Consortium: demographics, treatments, and outcomes, an international observational registry study. International Journal for Equity in Health, 22 (1) 260, 1-17. doi: 10.1186/s12939-023-02051-w
2023
Journal Article
Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies
McNicholas, Bairbre A., Rezoagli, Emanuele, Simpkin, Andrew J., Khanna, Sankalp, Suen, Jacky Y., Yeung, Pauline, Brodie, Daniel, Li Bassi, Gianluigi, Pham, Tai, Bellani, Giacomo, Fraser, John F. and Laffey, John (2023). Epidemiology and outcomes of early-onset AKI in COVID-19-related ARDS in comparison with non-COVID-19-related ARDS: insights from two prospective global cohort studies. Critical Care, 27 (1) 3, 1-14. doi: 10.1186/s13054-022-04294-5
2023
Journal Article
Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis
Obonyo, Nchafatso G., Sela, Declan P., Raman, Sainath, Rachakonda, Reema, Schneider, Bailey, Hoe, Louise E. See, Fanning, Jonathon P., Bassi, Gianluigi Li, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2023). Resuscitation-associated endotheliopathy (RAsE): a conceptual framework based on a systematic review and meta-analysis. Systematic Reviews, 12 (1) 221, 1-17. doi: 10.1186/s13643-023-02385-0
Funding
Current funding
Supervision
Availability
- Associate Professor Jacky Suen is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Available projects
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Sleep in the ICU
We are looking for a RHD student to be involved in a project investigating sleep in the ICU. The student will have access to formally collected sleep data under various ICU conditions and measured with various objective and subjective tools. The aim of the project includes validating new and innovative sleep measurement devices against the gold standard polysomnography, mapping sleep patterns and circadian rhythms of patients in ICU, and comparing sleep between different environmental conditions.
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Honours students for cardio-respiratory failure
We are looking for honours students to be involved in our range of studies on cardiac/respiratory failure. Projects include heart transplantation, acute respiratory failure, sepsis and advanced life support. Students will be expected and supported for grant application, as most of our previous honours students were awarded with $10,000 New Investigator Grant.
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Mitochondrial dysfunction and repair during circulatory death and heart transplantation
We are looking for Honours and RHD students to be involved in our NHMRC-funded heart transplantation program. Previously, we have successfully translated our research on extended organ preservation to clinical practice in Australia/New Zealand. As we explore on a new donor source, we are looking for talented students to join the team to study mitochondrial dysfunction, as a key parameter in determining post-transplant cardiac function.
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Systematic examination of ECMO parameters
Extra-Corporeal Membrane Oxygenation (ECMO) is an artificial heart/lung machine that is use to support patients with severe cardiac/respiratory failure. It has been invented for more than 30 years. To date, there is a lack of systematic examination of various parameters and settings for ECMO. Many of the current clinical practise are based on convention and tradition. This project aims to research and provide empirical evidences in order to optimise ECMO usage for patients, leading to improved patient outcome and reduced length of hospital stay. The project could involve bench-top ex vivo experiments, large animal in vivo study, and, perspective and retrospective analysis of clinical studies.
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Impact of blood flow for lung function
We are looking for Honours or RHD students to be involved in a project examining the impact of blood flow to support patients with respiratory failure. The student will be using human primary lung cells to model the condition of respiratory failure and advanced life support. The project will be in partnership with a leading biomed tech industry partner.
Supervision history
Current supervision
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Doctor Philosophy
An investigation of Veno-Arterial Extracorporeal Membrane Oxygenation (V-A ECMO) and its interaction with Continuous Renal Replacement Therapy (CRRT)
Principal Advisor
Other advisors: Professor John Fraser
-
Doctor Philosophy
The importance of blood flow pattern on ECMO and cardiogenic shock
Associate Advisor
Other advisors: Professor John Fraser
-
Doctor Philosophy
Vascular Endothelial Injury, Repair and Preconditioning in the Artificial Circulation
Associate Advisor
Other advisors: Professor John Fraser
-
Doctor Philosophy
Load-Independent Right Ventricular Assessment by Echocardiography
Associate Advisor
Other advisors: Professor John Fraser
Completed supervision
-
2023
Doctor Philosophy
The differences in coagulation disturbances of the Acute Respiratory Distress Syndrome subphenotypes
Principal Advisor
Other advisors: Professor John Fraser
-
2024
Doctor Philosophy
Development of Speckle-Tracking Echocardiographic strain accounting for cardiac loading conditions
Associate Advisor
Other advisors: Professor John Fraser
-
2023
Doctor Philosophy
A Comprehensive Pre-Clinical Evaluation of Pulsatile Flow Veno-arterial Extracorporeal Membrane Oxygenation
Associate Advisor
Other advisors: Professor John Fraser
-
2023
Doctor Philosophy
The Significance of Different Phenotypes in Acute Respiratory Distress Syndrome (ARDS) for Effective Treatment
Associate Advisor
Other advisors: Professor John Fraser
-
2022
Master Philosophy
Pre-clinical model development of electrical impedance tomography in the assessment of the pulmonary distribution of nebulized solutions
Associate Advisor
Other advisors: Associate Professor Jayesh Dhanani, Dr Gianluigi Li Bassi, Professor John Fraser
-
2021
Doctor Philosophy
Combining Extracorporeal Life Support and Cell Therapy in Critical Illness: Mesenchymal stem cell therapy and extracorporeal membrane oxygenation in the Acute Respiratory Distress Syndrome
Associate Advisor
Other advisors: Professor John Fraser
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2019
Doctor Philosophy
A Translational Approach to Potential Toxicity of Stored Blood Components
Associate Advisor
Other advisors: Dr John-Paul Tung, Professor John Fraser
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2018
Doctor Philosophy
Modulating Protease-Activated Receptor 2
Associate Advisor
Other advisors: Dr Junxian Lim, Professor David Fairlie
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2014
Doctor Philosophy
Properties of C5a Receptor on Human Macrophages
Associate Advisor
Other advisors: Professor David Fairlie
Media
Enquiries
Contact Associate Professor Jacky Suen directly for media enquiries about:
- Critical Care Medicine
- ECMO
- Extracorporeal Membrane Oxygenation
- Heart Failure
- Heart transplant
- Respiratory Failure
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