Professor Jeffrey Lipman
Professor

Jeffrey Lipman

Email: 
Phone: 
+61 7 334 65015
Phone: 
+61 7 3646 1847

Background

Prof Lipman is Executive Director of the Burns Trauma & Critical Care Research Centre; Professor of Anesthesiology & Critical Care, The University of Queensland and until recently (for 23 years) was Director of Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital; He holds Honorary Professorial appointments at Chinese University of Hong Kong, Unversity of Witwatersrand (South Africa) and Qeensland University of Technology.

He has qualifications in anesthesia and intensive care and has set up and been in charge of a number of Intensive Care and Trauma Units in South Africa before coming to Australia in 1997. he currently manages a large multidisciplinary research team with an output of over 120 peer-reviewed articles per annum. He has supervised dozens of PhD students to completion and is currently supervising 6 PhD, 1 MPhil and 1 MBBS/Hons students. Prof Lipman has been instrumental in developing the anaesthesiology and critical care component of a graduate medical program for Queensland and continues to lecture to medical and postgraduate students.

Prof Lipman is the author of over 550 peer reviewed publications, 30 book chapters and has been invited to deliver over 120 lectures at national and international conferences in many countries across the world. His research interests include all aspects of infection management in intensive care and he has a special interest in the pharmacokinetics of antibiotic dosage, an area in which he received his MD in 2006. His research into antibiotic usage in acute situations has received international recognition and he is regarded as an expert in the field. As such, he and his research team have conducted and presently conduct a number of clinical trials in Australia, New Zealand, Hong Kong, Europe and the UK.

Prof Lipman is an Editorial Board member for 10 International Journals, is Section Editor on four Antibiotic related Journals, reviews for 23 journals and is an external reviewer for NHMRC project grants (Local) as well as equivalent for a number overseas countries.

He is Chief Investigator on a 7000 patient International Randomised Controlled Trial comparing bolus dosing versus continuous infusions of meropenem and piperacillin-tazobactam

Availability

Professor Jeffrey Lipman is:
Not available for supervision
Media expert

Fields of research

Anaesthesiology Biomedical and Clinical Sciences Clinical pharmacology and therapeutics Clinical sciences Infectious diseases Intensive care Pharmacology and pharmaceutical sciences

Research interests

  • Antibiotic dosing in critically ill patients

    Severe sepsis is defined as failure of one or more organ systems, most commonly cardiovascular (including shock), respiratory and renal failure, caused by infection. Bacteria, either alone or in combination with other pathogens, are the most common cause of severe sepsis, and Gram-positive and Gram-negative organism account for up to 87% of culture positive episodes. Severe sepsis is a major cause of mortality worldwide. The ANZICS CTG reported that the Australian and New Zealand adult annual incidence of severe sepsis is 77 cases per 100,000,4 which is equivalent to over 17,000 patient episodes per year at an estimated cost per episode of AUD 42,300. Similar population incidence rates have been reported elsewhere. Importantly, 11.8% of all admissions to Australian and New Zealand ICUs are associated with severe sepsis and in-hospital mortality is 37.5%. In patients with septic shock, mortality approaches 60%. The burden of death is almost four times the annual national road toll. The death rate also exceeds other diseases that impact significantly on the Australian community, such as breast and colorectal cancer. In short, severe sepsis is a major public health concern in Australia and improved therapies are needed urgently. My research group is conducting national and international clinical trials investigating the effect of various dosing regimes on health outcomes in critically ill patients.

Research impacts

My research has been instrumental in changing antibiotic prescribing habits worldwide for critically ill patients, first with aminoglycosides (I did the first and still largest clinical trial to show single daily dosing to be effective) and more recently with beta-lactam antibiotics. Due to critically ill patients having altered pharmacokinetics, using standard antibiotic dosing for these patients is fraught with problems. This has led to the use of Therapeutic Drug Monitoring (TDM) for beta-lactams.

TDM of aminoglycosides and glycopeptides is performed to decrease side-effects of these drugs. Beta-lactams have a large therapeutic ratio and hence measurement of them is infrequent. I helped set up routine TDM of beta-lactam antibiotics at RBWH. I have changed how we dose patients particularly in ICU but also within the wards of RBWH. By means of TDM we have shown we need dose adjustments in 74% of patients to which we administer β-lactam antibiotics in the ICU (Roberts JA et al. Int J Antimicrob Agents 2010;36:332-39). Although scarcely performed world-wide, TDM of beta-lactams is now becoming more commonly performed. We are currently collating data from 5 International centres that also use TDM in an attempt to show outcome benefits of TDM and are starting to publish accordingly (Wong G et al. An international, multi-centre survey of beta-lactam antibiotics TDM practice in intensive care units. J Antimicrob Chemother 2014;69: 1416–1423).

Search Professor Jeffrey Lipman’s works on UQ eSpace

728 works between 1981 and 2025
All (728) Journal Article (685) Book Chapter (21) Conference Publication (16) Book (3) Other Outputs (3)

281 - 300 of 728 works

2016

Journal Article

Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients

Roger, Claire, Wallis, Steven C., Louart, Benjamin, Lefrant, Jean-Yves, Lipman, Jeffrey, Muller, Laurent and Roberts, Jason A. (2016). Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients. Journal of Antimicrobial Chemotherapy, 71 (6), 1643-1650. doi: 10.1093/jac/dkw043

Comparison of equal doses of continuous venovenous haemofiltration and haemodiafiltration on ciprofloxacin population pharmacokinetics in critically ill patients

2016

Journal Article

We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?

Cotta, Menino Osbert, Roberts, Jason A. and Lipman, Jeffrey (2016). We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?. Critical Care, 20 (1) 163. doi: 10.1186/s13054-016-1348-8

We need to optimize piperacillin-tazobactam dosing in critically ill patients-but how?

2016

Journal Article

Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists

Cotta, Menino O., Dulhunty, Joel M., Roberts, Jason A., Myburgh, John and Lipman, Jeffrey (2016). Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists. International Journal of Antimicrobial Agents, 47 (6), 436-438. doi: 10.1016/j.ijantimicag.2016.02.017

Should β-lactam antibiotics be administered by continuous infusion in critically ill patients? A survey of Australia and New Zealand intensive care unit doctors and pharmacists

2016

Journal Article

Is there a role for microsampling in antibiotic pharmacokinetic studies?

Parker, Suzanne L., Dorofaeff, Tavey, Lipman, Jeffrey, Ballot, Daynia E., Bandini, Rossella M., Wallis, Steven C. and Roberts, Jason A. (2016). Is there a role for microsampling in antibiotic pharmacokinetic studies?. Expert Opinion on Drug Metabolism and Toxicology, 12 (6), 601-614. doi: 10.1080/17425255.2016.1178238

Is there a role for microsampling in antibiotic pharmacokinetic studies?

2016

Journal Article

In 2035, will all bacteria be multidrug-resistant? No

Barbier, Francois, Lipman, Jeffrey and Bonten, Marc J. M. (2016). In 2035, will all bacteria be multidrug-resistant? No. Intensive Care Medicine, 42 (12), 1-4. doi: 10.1007/s00134-016-4348-x

In 2035, will all bacteria be multidrug-resistant? No

2016

Journal Article

Therapeutic drug monitoring of anti-infective agents in critically ill patients

Jager, Nynke G., van Hest, Reinier M., Lipman, Jeffrey, Taccone, Fabio S. and Roberts, Jason A. (2016). Therapeutic drug monitoring of anti-infective agents in critically ill patients. Expert Review of Clinical Pharmacology, 9 (7), 961-979. doi: 10.1586/17512433.2016.1172209

Therapeutic drug monitoring of anti-infective agents in critically ill patients

2016

Journal Article

A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit

Tabah, Alexis, Cotta, Menino Osbert, Garnacho-Montero, Jose, Schouten, Jeroen, Roberts, Jason A., Lipman, Jeffrey, Tacey, Mark, Timsit, Jean-Francois, Leone, Marc, Zahar, Jean Ralph and De Waele, Jan J. (2016). A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit. Clinical Infectious Diseases, 62 (8), 1009-1017. doi: 10.1093/cid/civ1199

A systematic review of the definitions, determinants, and clinical outcomes of antimicrobial de-escalation in the Intensive Care Unit

2016

Journal Article

The use and risks of antibiotics in critically ill patients

Denny, Kerina J., Cotta, Menino O., Parker, Suzanne L., Roberts, Jason A. and Lipman, Jeffrey (2016). The use and risks of antibiotics in critically ill patients. Expert Opinion on Drug Safety, 15 (5), 667-678. doi: 10.1517/14740338.2016.1164690

The use and risks of antibiotics in critically ill patients

2016

Journal Article

Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review

Alobaid, Abdulaziz S., Hites, Maya, Lipman, Jeffrey, Taccone, Fabio Silvio and Roberts, Jason A. (2016). Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review. International Journal of Antimicrobial Agents, 47 (4), 259-268. doi: 10.1016/j.ijantimicag.2016.01.009

Effect of obesity on the pharmacokinetics of antimicrobials in critically ill patients: a structured review

2016

Journal Article

CAMERA2-combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial

Tong, Steven Y. C., Nelson, Jane, Paterson, David L., Fowler, Vance G., Jr., Howden, Benjamin P., Cheng, Allen C., Chatfield, Mark, Lipman, Jeffrey, Van Hal, Sebastian, O'Sullivan, Matthew, Robinson, James O., Yahav, Dafna, Lye, David and Davis, Joshua S. (2016). CAMERA2-combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial. Trials, 17 (1) 170, 170. doi: 10.1186/s13063-016-1295-3

CAMERA2-combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial

2016

Journal Article

SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients

Roberts, Jason A., Choi, Gordon Y. S., Joynt, Gavin M., Paul, Sanjoy K., Deans, Renae, Peake, Sandra, Cole, Louise, Stephens, Dianne, Bellomo, Rinaldo, Turnidge, John, Wallis, Steven C., Roberts, Michael S., Roberts, Darren M., Lassig-Smith, Melissa, Starr, Therese and Lipman, Jeffrey (2016). SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients. Bmc Infectious Diseases, 16 (1) 103, 103.1-103.8. doi: 10.1186/s12879-016-1421-6

SaMpling antibiotics in renal replacement therapy (SMARRT): an observational pharmacokinetic study in critically ill patients

2016

Journal Article

Use of neostigmine for acute colonic pseudo-obstruction in a patient receiving dexmedetomidine

Dodds, Michelle M., Frazer, Callum D., Lipman, Jeffrey and Reade, Michael (2016). Use of neostigmine for acute colonic pseudo-obstruction in a patient receiving dexmedetomidine. Critical Care and Resuscitation, 18 (1), 59-61.

Use of neostigmine for acute colonic pseudo-obstruction in a patient receiving dexmedetomidine

2016

Journal Article

What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?

Alobaid, Abdulaziz S., Brinkmann, Alexander, Frey, Otto R., Roehr, Anka C., Luque, Sonia, Grau, Santiago, Wong, Gloria, Abdul-Aziz, Mohd-Hafiz, Roberts, Michael S., Lipman, Jeffrey and Roberts, Jason A. (2016). What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?. Journal of Antimicrobial Chemotherapy, 71 (3) dkv412, 696-702. doi: 10.1093/jac/dkv412

What is the effect of obesity on piperacillin and meropenem trough concentrations in critically ill patients?

2016

Journal Article

Severity scores in emergency department patients with presumed infection: a prospective validation study

Williams, Julian M., Greenslade, Jaimi H., Chu, Kevin, Brown, Anthony F. T. and Lipman, Jeffrey (2016). Severity scores in emergency department patients with presumed infection: a prospective validation study. Critical Care Medicine, 44 (3), 539-547. doi: 10.1097/CCM.0000000000001427

Severity scores in emergency department patients with presumed infection: a prospective validation study

2016

Journal Article

In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis

Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Lassig-Smith, Melissa, Starr, Therese, Robertson, Thomas, Peake, Sandra L. and Roberts, Jason A. (2016). In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis. Antimicrobial Agents and Chemotherapy, 60 (2), 827-832. doi: 10.1128/AAC.02461-15

In vivo microdialysis to determine subcutaneous interstitial fluid penetration and pharmacokinetics of fluconazole in intensive care unit patients with sepsis

2016

Journal Article

Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration

Roger, C., Muller, L., Wallis, S. C., Louart, B., Saissi, G., Lipman, J., Lefrant, J. Y. and Roberts, J. A. (2016). Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 71 (2) dkv349, 464-470. doi: 10.1093/jac/dkv349

Population pharmacokinetics of linezolid in critically ill patients on renal replacement therapy: comparison of equal doses in continuous venovenous haemofiltration and continuous venovenous haemodiafiltration

2016

Journal Article

EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeability

Woodruff, Trent M., Wu, Mike C.-L., Morgan, Michael, Bain, Nathan T., Jeanes, Angela, Lipman, Jeffrey, Ting, Michael J., Boyd, Andrew W., Taylor, Stephen M. and Coulthard, Mark G. (2016). EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeability. Shock, 45 (2), 184-191. doi: 10.1097/SHK.0000000000000494

EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeability

2016

Journal Article

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

Abdul-Aziz, Mohd H., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Dulhunty, Joel, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Roberts, Jason A., Paul, Sanjoy, Ribas, Antonio Margarit, De Crop, Luc, Spapen, Herbert, Wauters, Joost, Dugernier, Thierry, Jorens, Philippe, Dapper, Ilse, De Backer, Daniel, Taccone, Fabio S., Ruano, Laura, Afonso, Elsa, Alvarez-Lerma, Francisco ... Ozveren, Arife (2016). Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort. Journal of Antimicrobial Chemotherapy, 71 (1), 196-207. doi: 10.1093/jac/dkv288

Is prolonged infusion of piperacillin/tazobactam and meropenem in critically ill patients associated with improved pharmacokinetic/pharmacodynamic and patient outcomes? An observation from the Defining Antibiotic Levels in Intensive care unit patients (DALI) cohort

2016

Conference Publication

“Early epidural analgesia”: Practice guidelines are interpreted variably by specialist anaesthetists caring for obese parturients

Eley, Victoria , Callaway, Leonie , van Zundert, Andre , Lipman, Jeffrey and Gallois, Cindy (2016). “Early epidural analgesia”: Practice guidelines are interpreted variably by specialist anaesthetists caring for obese parturients. Australian and New Zealand College of Anaesthetists Annual Scientific Meeting, Auckland, New Zealand, April 30- May 4th 2016.

“Early epidural analgesia”: Practice guidelines are interpreted variably by specialist anaesthetists caring for obese parturients

2016

Journal Article

Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit

Abdul-Aziz, Mohd H., Abd Rahman, Azrin N., Mat-Nor, Mohd-Basri, Sulaiman, Helmi, Wallis, Steven C., Lipman, Jeffrey, Roberts, Jason A. and Staatz, Christine E. (2016). Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit. Antimicrobial Agents and Chemotherapy, 60 (1), 206-214. doi: 10.1128/AAC.01543-15

Population pharmacokinetics of doripenem in critically ill patients with sepsis in a Malaysian intensive care unit

Current funding

  • 2021 - 2026
    Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
    NHMRC Centres of Research Excellence
    Open grant
  • 2015 - 2025
    TxA levels in the PATCH-Trauma trial
    Intensive Care Foundation
    Open grant
  • 2014 - 2025
    Research donations in support of the Burns Trauma and Critical Care Research Centre
    Royal Brisbane and Women's Hospital Foundation
    Open grant

Past funding

  • 2023
    Assessing the level of adherence to the new developed work-based oral care bundles for critical care patients to ensure service quality
    Australian Dental Research Fund Inc
    Open grant
  • 2022 - 2023
    Assessing the level of adherence to current work-based guidelines in oral care for critical care patients to improve service quality
    Metro North Hospital and Health Service
    Open grant
  • 2022 - 2023
    Investigating Metabolic Acidosis in Gastroenterology Induced by Colonoscopy preparation and Sodium glucose transporter 2 inhibitors: The MAGICS Study (MSH HHS Project Grant administered by MSH HHS)
    Metro South Hospital and Health Service
    Open grant
  • 2021 - 2023
    Continuous vs intermittent infusion of beta-lactam antibacterial drugs: impact on resistance and outcomes in sepsis - PMWP 170
    United States Food and Drug Administration
    Open grant
  • 2021 - 2022
    Developing evidence-based antibiotic dosing guidelines during extracorporeal therapies using advanced pharmacometric methods... (RBWH grant administered by UQ)
    Metro North Hospital and Health Service
    Open grant
  • 2020 - 2021
    The effect of extracorporeal membrane oxygenation (ECMO) on the effectiveness of Coronavirus Disease 2019 (COVID-19) pharmacotherapy - ex vivo characterisation and quantification [...]
    Metro North Hospital and Health Service
    Open grant
  • 2020
    Rapid detection of resistance genes from Gram-negative bacteria isolated from blood in ICU-admitted patients
    Pathology Queensland - Study, Education & Research Trust Fund
    Open grant
  • 2019 - 2021
    Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients (Led by MNHHS)
    Metro North Hospital and Health Service
    Open grant
  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2024
    Novel dosing regimens to maximise antibiotic effectiveness for treatment of pneumonia in the intensive care unit
    NHMRC Project Grant
    Open grant
  • 2018
    Effect of albumin resuscitation on drug pharmacokinetics in low protein and LPS challenged sheep
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2018
    Ion Mobility Separation of Challenging Clinical Samples
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2019
    Nuclear medicine suite for animals
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2019
    Pharmacokinetic-pharmacodynamic substudy of patients with severe sepsis randomised to receive beta-lactam antibiotics by either intermittent or continuous infusion.
    Metro North Hospital and Health Service
    Open grant
  • 2017 - 2018
    Does routine antibiotic administration in overweight women having elective caesarean section achieve therapeutic levels?
    Metro North Hospital and Health Service
    Open grant
  • 2017
    Implementing microsampling into clinical pharmacokinetic research studies - it only takes a drop of blood!
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2017 - 2018
    Pharmacokinetic-pharmacodynamic substudy of patients with severe sepsis randomised to receive beta-lactam antibiotics by either intermittent or continuous infusion
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016 - 2018
    Using a drop of blood to personalise antibiotic dosing in children and prevent antibiotic resistance
    Ian Potter Foundation
    Open grant
  • 2016 - 2019
    A biomarker for Sepsis to thwart antibiotic overuse in the Intensive Care Unit
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2016
    Pharmacokinetic/Pharmacodynamic (PK/PD) analysis of antimicrobials in renal replacement therapy (RRT) and septic shock
    University Hospital of Nîmes
    Open grant
  • 2015 - 2021
    Centre for REdefining antibiotic use to reDUce resistanCE and prolong the lives of antibiotics (REDUCE)
    NHMRC Centres of Research Excellence
    Open grant
  • 2015 - 2017
    SoM Leaders Research Support for Head Academic Discipline of Anaesthesiology and Critical Care
    Mayne Bequest Fund
    Open grant
  • 2015
    Pharmacokinetic Australasian Collaborative
    Intensive Care Foundation
    Open grant
  • 2015 - 2016
    A biomarker for sepsis to thwart antibiotic overuse in the intensive care unit
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015
    Addressing an unmet need by establishing a state-of-the-art translational model at UQ: The hollow fibre in vitro infection model
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015 - 2019
    CAMERA 2: Combination antibiotic treatment for methicillin resistant Staphylococcus aureus bacteraemia - a randomised controlled trial (NHMRC Project Grant administered by Menzies)
    Menzies School of Health Research
    Open grant
  • 2015
    Incidence, risk factors, consequences and treatment of ventilated patients with nosocomial infection with pandrug resistant organisms in hospitals in Asia
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2015
    Pilot randomised controlled trial of meropenem versus piperacillin-tazobactam for the definitive treatment of bloodstream infections caused by AmpC beta-lactamase producing Enterobacter spp, ...
    Royal Brisbane and Women's Hospital
    Open grant
  • 2014 - 2015
    Interventional multi-centre prospective epidemiological study of ventilator-associated pneumonia
    Royal Brisbane and Women's Hospital
    Open grant
  • 2014 - 2015
    A Phase II randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients
    Auckland District Health Board Charitable Trust
    Open grant
  • 2014 - 2017
    Innovative dosing approaches to maximise bacterial killing and prevent resistance in septic critically ill patients
    NHMRC Project Grant
    Open grant
  • 2014
    Strenghtening the School of Medicine's position as a central coordinator of global pharmacokenetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2014
    Randomised controlled trial of beta-lactam continuous infusion compared with intermittent dosing in critically ill patients
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013 - 2016
    Robust antibiotic dosing for critically ill patients receiving renal replacement therapy
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    A phase IIb randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients (Special Purpose Grant BTCCRC)
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2012 - 2017
    A Phase IIb Randomised Controlled Trial of Continuous Beta-Lactam Infusion Compared With Intermittent Beta-Lactam Dosing in Critically Ill Patients With Severe Sepsis
    Baxter Healthcare Pty Ltd
    Open grant
  • 2012 - 2015
    A phase IIb randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis
    NHMRC Project Grant
    Open grant
  • 2012
    Facilitating School of Medicine as a central coordinator of global pharmacokinetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2014
    Identifying a cost-effective approach to MRSA control in Australia (NHMRC Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2012 - 2015
    Pilot Study of pharmacokinetic and pharmacodynamic assessment of monotherapy versus combination therapy for the management of gram negative bacteraemia
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012 - 2015
    Prevention of Ventilator Associated Pneumonia by Inhaled Heparin
    Australian and New Zealand Intensive Care Foundation
    Open grant
  • 2012
    Tandem fluorescent and phase-contrast imaging of live cells in real time for application to cancer cell biology, developmental biology, respiratory biology, wound healing investigation and cellular to
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2013
    UQ/UWA joint project on Severe Sepsis
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2011 - 2013
    Microdialysis to monitor fluid shifts and predict organ failure in the systemic inflammatory response syndrome
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2011 - 2012
    DALI: Defining antibiotic levels in intensive care unit patients
    European Society of Intensive Care Medicine
    Open grant
  • 2010 - 2012
    Examining Sepsis in the Emergency Department
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2015
    Microcirculation in shocked patients
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2016
    Tamsulosin for the treatment of Distal Ureteric Calculi: A double-blinded, placebo-controlled, randomised, multi-centre trial
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2010 - 2011
    Pilot RCT of continuous beta-lactam infusion compared with intermittent dosing in critically ill patients
    Australian and New Zealand Intensive Care Foundation
    Open grant
  • 2010
    Improving outcomes post major trauma
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010 - 2012
    Pharmacokinetics in continuous venovenous haemodiafiltration (CVVHDF) - using plasma and tissue antibiotic concentrations to optimise dosing of beta-lactam antibodies
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2012
    Mayne Bequest Fund Research Support Award: Sepsis and Intensive Care
    Mayne Bequest Fund
    Open grant
  • 2009 - 2011
    Myocardial function in burns: A Prospective and observational study
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2014
    Assessment of the Microcirculation in Shocked Critically Unwell Patients during the first 24 hours of resuscitation
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2011
    Pharmacokinetics of Cephalothin, Vancomycin and Gentamicin Used for Antimicrobial Prophylaxis during elective abdominal aortic aneurysm surgery
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2009 - 2011
    Glomerular Hyperfiltration in at risk patients on Admission to the Intensive Care Unit (GHAU) Study
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009
    Improving outcomes post burn injury
    UQ School/Centre Co-Funding
    Open grant
  • 2009 - 2014
    Inhaled Prophylactic-Heparin In Ventilator Associated Pneumonia Prevention Trial (IPHAPP)
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2011
    The Sepsis Registry: A prospective database to characterise and facilitate improved outcome for admitted patients with community-acquired infection
    QEMRF Emergency Medicine Staff Specialist Research Grants Scheme
    Open grant
  • 2008 - 2010
    Antibiotic dosing in the at risk critically ill patient
    NHMRC Project Grant
    Open grant
  • 2008
    Imaging of the microcirculation using the Microscan (orthogonal polarization spectral imaging) and providing improved quality of drug analysis for PK studies in critically ill patients
    NHMRC Equipment Grant
    Open grant
  • 2008
    Improved quantification of spatial and temporal changes in plasma and tissue drug levels and tissue pathology
    NHMRC Equipment Grant
    Open grant
  • 2007
    Multi-drug resistant Acinetobacter: an emerging nosocomial pathogen
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2006 - 2007
    Microdialysis in antibiotic dosing, pain management and neurosurgical outcome
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2006
    NHMRC_Infrastructure Item_Metabolic Exercise System, MetaMax Portable CPX
    Open grant
  • 2006 - 2007
    Pharmacokinetic Modelling of Various B-lactam Antibiotics in Critically-ill Patients using Microdialysis
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2005
    Advanced auditory displays for patient monitoring in anesthesia and intensive care
    University of Queensland Research Development Grants Scheme
    Open grant
  • 2005 - 2007
    Management of burn injury: Fluid dynamics and antibiotic pharmacokinetics
    NHMRC Project Grant
    Open grant
  • 2005
    NHMRC Equipment Grant : Estimation of drugs, peptides and metabolites using HPLC-Mass-spectrometry-microdialysis
    NHMRC Equipment Grant
    Open grant
  • 2005
    Optimal Antibiotic Dosing in Burns: Fluid Dynamics and Drug Tissue Pharmacokinetics
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2005 - 2006
    Start-up Grant
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2005 - 2008
    Study of Risk Assessment To reduce complications In patients Following noncardiac surgerY (STRATIFY)
    NHMRC Project Grant
    Open grant
  • 2005 - 2006
    Supplementary funding to advance development
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2004 - 2015
    Burns, Trauma, Critical Care Research Centre
    Royal Women's Hospital Research & Development Foundation
    Open grant
  • 2004 - 2009
    Burns, Trauma and Critical Care Research Centre
    Mayne Bequest Fund
    Open grant

Availability

Professor Jeffrey Lipman is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Professor Jeffrey Lipman directly for media enquiries about:

  • Antibiotics
  • Intensive care
  • pharmacokinetics

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