Emeritus Professor Istvan Toth
Emeritus Professor

Istvan Toth

Email: 

Background

Professor István Tóth is Chair in Biological Chemistry at The University of Queensland (UQ), Brisbane, Australia, and Affiliated Professorial Research Fellow at the Institute of Molecular Biosciences, UQ. He graduated with a degree in Chemical Engineering from the Technical University, Budapest, Hungary and was awarded his PhD for his Alkaloid Chemistry research. Professor Tóth undertook a postdoctoral fellowship at Carleton University, Ottawa Canada before returning to Hungary to work as a Research Associate, then Scientific Group Leader at the Central Research Institute for Chemistry, Hungarian Academy of Science. He joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 and was awarded a Doctor of Science degree (DSc 1994) for his work in Drug Delivery (Hungarian Academy of Sciences), before relocating to the University of Queensland in 1998 where he has built a productive research group. Professor Tóth was a visiting professor at the School of Pharmacy, University of London (1994-2004) and at the Department of Bioengineering and Therapeutic Science, University of California, San Francisco (2011-2013). Professor Tóth’s major research interests are: drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides, and nucleotides. This research has attracted over $85 million in competitive grants, research contracts and investment funds in the past 10 years. Professor Tóth has over 500 peer-reviewed publications, 45 patents, and an excellent track record in research commercialisation. He is a one of key founders of Alchemia, Implicit Bioscience Pty Ltd, Neurotide Pty Ltd and TetraQ (the commercial arm of Centre of Integrated Preclinical Drug Development). Professor Tóth is an elected RACI Fellow and Fellow of the Queensland Academy of Arts and Sciences. and Feklloiw of the Hungarian Academy of Sciences (since 2016) In 2009 he was awarded the Adrian Albert award for sustained and outstanding research in medicinal biochemistry, and a Business/Higher Education Round Table (BHERT) Award for Outstanding Achievement in International Collaborative Research and Development he obtained the Doctor Honoris Causa degree at Semmelweis university budapest Hungary (2019). Professor Tóth was appointed as a member of the ARC College of Experts (2008-2010). He was the founding (2007) then the elected (2008-2009) President of the Australian Chapter of Controlled Release Society.

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision
Media expert

Fields of research

Medicinal and biomolecular chemistry Organic chemistry

Qualifications

  • Doctor of Philosophy of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics
  • Doctoral Diploma of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics

Search Professor Istvan Toth’s works on UQ eSpace

683 works between 1972 and 2025
All (683) Journal Article (480) Book Chapter (42) Conference Publication (151) Book (3) Other Outputs (6) Edited Outputs (1)

641 - 660 of 683 works

1992

Journal Article

Lipidic peptides. XIII: Synthesis, structure elucidation and in vitro toxicity assessment of chlorambucil conjugates with lipidic acids, lipidic amino acids and their oligomers

Wood, IP, Toth, I, Holley, JL and Gibbons, WA (1992). Lipidic peptides. XIII: Synthesis, structure elucidation and in vitro toxicity assessment of chlorambucil conjugates with lipidic acids, lipidic amino acids and their oligomers. International Journal of Pharmaceutics, 87 (1-3), 141-147. doi: 10.1016/0378-5173(92)90237-V

Lipidic peptides. XIII: Synthesis, structure elucidation and in vitro toxicity assessment of chlorambucil conjugates with lipidic acids, lipidic amino acids and their oligomers

1992

Journal Article

Lipidic Peptides .14. Conversion of Racemic Lipidic Amino-Acids Into Sphingosine and Ceramide Analogs and 1,2-Diamines

Kokotos, G., Constantinoukokotou, V., Fernandez, E.D., Toth, I. and Gibbons, W.A. (1992). Lipidic Peptides .14. Conversion of Racemic Lipidic Amino-Acids Into Sphingosine and Ceramide Analogs and 1,2-Diamines. Liebigs Annalen der Chemie, 1992 (9), 961-964. doi: 10.1002/jlac.1992199201158

Lipidic Peptides .14. Conversion of Racemic Lipidic Amino-Acids Into Sphingosine and Ceramide Analogs and 1,2-Diamines

1992

Journal Article

Lipidic Peptides .5. Penicillin and Cephalosporin Acid Conjugates with Increased Lipophilic Character

Hughes, RA, Toth, I, Ward, P, McColm, AM, Cox, DM, Anderson, GJ and Gibbons, WA (1992). Lipidic Peptides .5. Penicillin and Cephalosporin Acid Conjugates with Increased Lipophilic Character. Journal of Pharmaceutical Sciences, 81 (8), 845-848. doi: 10.1002/jps.2600810826

Lipidic Peptides .5. Penicillin and Cephalosporin Acid Conjugates with Increased Lipophilic Character

1992

Journal Article

Synthesis and Spectroscopy of Membrane-Receptor Proteins - the Gamma Subunit of the Ige Receptor

Anderson, GJ, Haris, PI, Chapman, D, Romer, JT, Toth, GK, Toth, I and Gibbons, WA (1992). Synthesis and Spectroscopy of Membrane-Receptor Proteins - the Gamma Subunit of the Ige Receptor. European Journal of Biochemistry, 207 (1), 51-54. doi: 10.1111/j.1432-1033.1992.tb17018.x

Synthesis and Spectroscopy of Membrane-Receptor Proteins - the Gamma Subunit of the Ige Receptor

1992

Journal Article

LIPIDIC PEPTIDES .12. CELLULAR UPTAKE STUDIES OF A LIPIDIC AMINO-ACID, ITS OLIGOMERS AND HIGHLY LIPOPHILIC DRUG CONJUGATES ON EHRLICH ASCITES TUMOR-CELLS

TOTH, , FERNANDEZ, ED, HAFEEZ, RA, HOLLEY, JL, WOOD, IP, WARD, P and GIBBONS, WA (1992). LIPIDIC PEPTIDES .12. CELLULAR UPTAKE STUDIES OF A LIPIDIC AMINO-ACID, ITS OLIGOMERS AND HIGHLY LIPOPHILIC DRUG CONJUGATES ON EHRLICH ASCITES TUMOR-CELLS. International Journal of Pharmaceutics, 83 (1-3), 131-138. doi: 10.1016/0378-5173(82)90015-1

LIPIDIC PEPTIDES .12. CELLULAR UPTAKE STUDIES OF A LIPIDIC AMINO-ACID, ITS OLIGOMERS AND HIGHLY LIPOPHILIC DRUG CONJUGATES ON EHRLICH ASCITES TUMOR-CELLS

1992

Journal Article

Lipid methyl transferase inhibitory activity of novel α-amino alkylic acid derivatives

Delolmo, E, Toth, I, Fonteh, AN and Gibbons, WA (1992). Lipid methyl transferase inhibitory activity of novel α-amino alkylic acid derivatives. International Journal of Pharmaceutics, 81 (2-3), 267-269. doi: 10.1016/0378-5173(92)90019-X

Lipid methyl transferase inhibitory activity of novel α-amino alkylic acid derivatives

1992

Journal Article

Lipidic peptides. VIII. Cellular uptake studies of lipidic amino acid, its oligomers and highly lipophilic drug conjugates

Toth, I, Griffith, IP, Fernandez, ED, Hafeez, RA, Holley, JL, Ward, P and Gibbons, WA (1992). Lipidic peptides. VIII. Cellular uptake studies of lipidic amino acid, its oligomers and highly lipophilic drug conjugates. International Journal of Pharmaceutics, 79 (1-3), 39-45. doi: 10.1016/0378-5173(92)90091-F

Lipidic peptides. VIII. Cellular uptake studies of lipidic amino acid, its oligomers and highly lipophilic drug conjugates

1992

Journal Article

Lipidic Peptides, IX. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1992). Lipidic Peptides, IX. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers. Liebigs Annalen der Chemie, 1992 (2), 169-171. doi: 10.1002/jlac.199219920131

Lipidic Peptides, IX. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers

1992

Journal Article

Lipidic Peptides, IX. Synthesis and Structural Elucidation of Lipophilic Azidothymidine Conjugates

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1992). Lipidic Peptides, IX. Synthesis and Structural Elucidation of Lipophilic Azidothymidine Conjugates. Liebigs Annalen der Chemie, 1992 (2), 169-171. doi: 10.1002/jlac.199219920131

Lipidic Peptides, IX. Synthesis and Structural Elucidation of Lipophilic Azidothymidine Conjugates

1992

Book Chapter

Synthesis of lipidic peptide conjugates of nucleoside antiviral and cytostatic agents

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1992). Synthesis of lipidic peptide conjugates of nucleoside antiviral and cytostatic agents. Peptides. (pp. 450-451) Dordrecht, The Netherlands: Springer Netherlands. doi: 10.1007/978-94-011-2264-1_170

Synthesis of lipidic peptide conjugates of nucleoside antiviral and cytostatic agents

1992

Book Chapter

Synthesis and biological activity of heteroalkyl lipidic amino acids

del Olmo, Esther, Toth, Istvan, Fonteh, Alfred N. and Gibbons, William A. (1992). Synthesis and biological activity of heteroalkyl lipidic amino acids. Peptides. (pp. 452-453) Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/978-94-011-2264-1_171

Synthesis and biological activity of heteroalkyl lipidic amino acids

1992

Journal Article

Lipidic peptides X. Synthesis, structural and physico-chemical elucidation of lipidic amino acid conjugates with hydrophilic compounds

Toth, I, Anderson, GJ, Hussain, R, Wood, IP, Fernandez, ED, Ward, P and Gibbons, WA (1992). Lipidic peptides X. Synthesis, structural and physico-chemical elucidation of lipidic amino acid conjugates with hydrophilic compounds. Tetrahedron, 48 (5), 923-930. doi: 10.1016/S0040-4020(01)88194-1

Lipidic peptides X. Synthesis, structural and physico-chemical elucidation of lipidic amino acid conjugates with hydrophilic compounds

1991

Journal Article

Lipidic Peptides .3. Lipidic Amino-Acid and Oligomer Conjugates of Morphine

Hughes, RA, Toth, I, Ward, P, Ireland, SJ and Gibbons, WA (1991). Lipidic Peptides .3. Lipidic Amino-Acid and Oligomer Conjugates of Morphine. Journal of Pharmaceutical Sciences, 80 (12), 1103-1105. doi: 10.1002/jps.2600801202

Lipidic Peptides .3. Lipidic Amino-Acid and Oligomer Conjugates of Morphine

1991

Journal Article

FATTY PEPTIDES .6. PENICILLIN AND CEPHALOSPORIN ESTERS WITH INCREASED LIPOPHILIC CHARACTER

TOTH, , HUGHES, RA, WARD, P, MCCOLM, AM, COX, DM, ANDERSON, GJ and GIBBONS, WA (1991). FATTY PEPTIDES .6. PENICILLIN AND CEPHALOSPORIN ESTERS WITH INCREASED LIPOPHILIC CHARACTER. International Journal of Pharmaceutics, 77 (1), 13-20.

FATTY PEPTIDES .6. PENICILLIN AND CEPHALOSPORIN ESTERS WITH INCREASED LIPOPHILIC CHARACTER

1991

Journal Article

Lipidic Peptides .7. Synthesis and Structure Elucidation of Gamma-Aminobutyric-Acid Conjugates with Lipidic Acids, Lipidic Amino-Acids and Lipidic Peptides

Hussain, Rohanah, Toth, Istvan and Gibbons, William A. (1991). Lipidic Peptides .7. Synthesis and Structure Elucidation of Gamma-Aminobutyric-Acid Conjugates with Lipidic Acids, Lipidic Amino-Acids and Lipidic Peptides. Liebigs Annalen der Chemie, 1991 (9), 963-966. doi: 10.1002/jlac.1991199101165

Lipidic Peptides .7. Synthesis and Structure Elucidation of Gamma-Aminobutyric-Acid Conjugates with Lipidic Acids, Lipidic Amino-Acids and Lipidic Peptides

1991

Journal Article

Lipidic peptides. IV. Penicillin and cephalosporin amide conjugates with lipidic amino acids and their oligomers

Toth, I, Hughes, RA, Ward, P, Baldwin, MA, Welham, KJ, McColm, AM, Cox, DM and Gibbons, WA (1991). Lipidic peptides. IV. Penicillin and cephalosporin amide conjugates with lipidic amino acids and their oligomers. International Journal of Pharmaceutics, 73 (3), 259-266. doi: 10.1016/0378-5173(91)90418-N

Lipidic peptides. IV. Penicillin and cephalosporin amide conjugates with lipidic amino acids and their oligomers

1991

Journal Article

Lipidic peptides. II. Synthesis, activity and transport of anti-inflammatory benzoquinolizine-lipidic peptide conjugates

Toth, I, Hughes, RA, Munday, MR, Murphy, CA, Mascagni, P and Gibbons, WA (1991). Lipidic peptides. II. Synthesis, activity and transport of anti-inflammatory benzoquinolizine-lipidic peptide conjugates. International Journal of Pharmaceutics, 68 (1-3), 191-198. doi: 10.1016/0378-5173(91)90141-A

Lipidic peptides. II. Synthesis, activity and transport of anti-inflammatory benzoquinolizine-lipidic peptide conjugates

1991

Conference Publication

Brain uptake of lipophilic γ-aminobutyric acid conjugate

Hussain, R., Toth, I., Bowery, N. G. and Gibbons, A. (1991). Brain uptake of lipophilic γ-aminobutyric acid conjugate.

Brain uptake of lipophilic γ-aminobutyric acid conjugate

1991

Journal Article

Low dose aminoglutethimide therapy without glycocorticoid administration. Clinical and hormonal findings

Kahan Zs., Zs, Toth, I. and Vecsernyes, M. (1991). Low dose aminoglutethimide therapy without glycocorticoid administration. Clinical and hormonal findings. Magyar Onkologia, 35 (1), 7-12.

Low dose aminoglutethimide therapy without glycocorticoid administration. Clinical and hormonal findings

1991

Conference Publication

Antiamoebic testing of some natural and synthetic compounds structurally related to berberine

Wright, C. W., Toth, I., Phillipson, J. D. and Warhurst, D. C. (1991). Antiamoebic testing of some natural and synthetic compounds structurally related to berberine.

Antiamoebic testing of some natural and synthetic compounds structurally related to berberine

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Emeritus Professor Istvan Toth directly for media enquiries about:

  • Chemistry - lipid
  • Chemistry - medicinal
  • Chemistry - peptide
  • Chemistry - sugar
  • Drug - oral administration
  • Drug delivery
  • Genes and vaccines
  • Immunisation
  • Lipid chemistry
  • Medicinal chemistry
  • Oral administration of vaccines
  • Peptide chemistry
  • Peptide drug delivery
  • Sugar chemistry
  • Vaccines - oral administration
  • Vaccines and genes

Need help?

For help with finding experts, story ideas and media enquiries, contact our Media team:

communications@uq.edu.au