Emeritus Professor Istvan Toth
Emeritus Professor

Istvan Toth

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Background

Professor István Tóth is Chair in Biological Chemistry at The University of Queensland (UQ), Brisbane, Australia, and Affiliated Professorial Research Fellow at the Institute of Molecular Biosciences, UQ. He graduated with a degree in Chemical Engineering from the Technical University, Budapest, Hungary and was awarded his PhD for his Alkaloid Chemistry research. Professor Tóth undertook a postdoctoral fellowship at Carleton University, Ottawa Canada before returning to Hungary to work as a Research Associate, then Scientific Group Leader at the Central Research Institute for Chemistry, Hungarian Academy of Science. He joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 and was awarded a Doctor of Science degree (DSc 1994) for his work in Drug Delivery (Hungarian Academy of Sciences), before relocating to the University of Queensland in 1998 where he has built a productive research group. Professor Tóth was a visiting professor at the School of Pharmacy, University of London (1994-2004) and at the Department of Bioengineering and Therapeutic Science, University of California, San Francisco (2011-2013). Professor Tóth’s major research interests are: drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides, and nucleotides. This research has attracted over $85 million in competitive grants, research contracts and investment funds in the past 10 years. Professor Tóth has over 500 peer-reviewed publications, 45 patents, and an excellent track record in research commercialisation. He is a one of key founders of Alchemia, Implicit Bioscience Pty Ltd, Neurotide Pty Ltd and TetraQ (the commercial arm of Centre of Integrated Preclinical Drug Development). Professor Tóth is an elected RACI Fellow and Fellow of the Queensland Academy of Arts and Sciences. and Feklloiw of the Hungarian Academy of Sciences (since 2016) In 2009 he was awarded the Adrian Albert award for sustained and outstanding research in medicinal biochemistry, and a Business/Higher Education Round Table (BHERT) Award for Outstanding Achievement in International Collaborative Research and Development he obtained the Doctor Honoris Causa degree at Semmelweis university budapest Hungary (2019). Professor Tóth was appointed as a member of the ARC College of Experts (2008-2010). He was the founding (2007) then the elected (2008-2009) President of the Australian Chapter of Controlled Release Society.

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision
Media expert

Fields of research

Medicinal and biomolecular chemistry Organic chemistry

Qualifications

  • Doctor of Philosophy of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics
  • Doctoral Diploma of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics

Search Professor Istvan Toth’s works on UQ eSpace

683 works between 1972 and 2025
All (683) Journal Article (480) Book Chapter (42) Conference Publication (151) Book (3) Other Outputs (6) Edited Outputs (1)

661 - 680 of 683 works

1990

Journal Article

Lipidic peptides, I. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers

Gibbons, William A., Hughes, Richard A., Charalambous, Mario, Christodoulou, Marika, Szeto, Alice, Aulabaugh, Anne E., Mascagni, Paolo and Toth, Istvan (1990). Lipidic peptides, I. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers. Liebigs Annalen der Chemie, 1990 (12), 1175-1183. doi: 10.1002/jlac.1990199001215

Lipidic peptides, I. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo‐ and hetero‐oligomers

1990

Journal Article

HODGKINS-DISEASE AFTER NON-HODGKINS MALIGNANT-LYMPHOMA IN ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME

SENALDI, E, LEE, MH, TOTH, and GRACE, W (1990). HODGKINS-DISEASE AFTER NON-HODGKINS MALIGNANT-LYMPHOMA IN ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME. Cancer, 66 (5), 960-964. doi: 10.1002/1097-0142(19900901)66:53.0.CO;2-3

HODGKINS-DISEASE AFTER NON-HODGKINS MALIGNANT-LYMPHOMA IN ACQUIRED-IMMUNE-DEFICIENCY-SYNDROME

1990

Journal Article

Influence of the 60-megadalton plasmid on adherence of Escherichia coli 0157:H7 and genetic derivatives

Toth, I., Cohen, M. L., Rumschlag, H. S., Riley, L. W., White, E. H., Carr, J. H., Bond, W. W. and Wachsmuth, I. K. (1990). Influence of the 60-megadalton plasmid on adherence of Escherichia coli 0157:H7 and genetic derivatives. Infection and Immunity, 58 (5), 1223-1231. doi: 10.1128/IAI.58.5.1223-1231.1990

Influence of the 60-megadalton plasmid on adherence of Escherichia coli 0157:H7 and genetic derivatives

1988

Journal Article

Hydride abstraction in fast atom bombardment

Baldwin, MA, Welham, KJ, Toth, I and Gibbons, WA (1988). Hydride abstraction in fast atom bombardment. Organic Mass Spectrometry, 23 (10), 697-699. doi: 10.1002/oms.1210231004

Hydride abstraction in fast atom bombardment

1987

Journal Article

Berbanes: A New Class of Selective α2-adrenoceptor Antagonists

Vizi, E. Sylvester, Toth, Istvan, Somogyi, George T., Szabo, Lajos, Harsing, Laszlo G. and Szantay, Csaba (1987). Berbanes: A New Class of Selective α2-adrenoceptor Antagonists. Journal of Medicinal Chemistry, 30 (8), 1355-1359. doi: 10.1021/jm00391a015

Berbanes: A New Class of Selective α2-adrenoceptor Antagonists

1987

Journal Article

Investigations on the Chemistry of Berbanes, XIII. Selective Reduction of Normal‐, Allo‐, Pseudo‐, and Epiallo‐Depyrrolo‐Yohimbone Analogues

Tóth, István, Bozsár, Gabriella, Szabó, Lajos, Tamás, József, Baitz‐Gács, Eszter and Szántay, Csaba (1987). Investigations on the Chemistry of Berbanes, XIII. Selective Reduction of Normal‐, Allo‐, Pseudo‐, and Epiallo‐Depyrrolo‐Yohimbone Analogues. Liebigs Annalen der Chemie, 1987 (12), 1021-1024. doi: 10.1002/jlac.198719870867

Investigations on the Chemistry of Berbanes, XIII. Selective Reduction of Normal‐, Allo‐, Pseudo‐, and Epiallo‐Depyrrolo‐Yohimbone Analogues

1987

Journal Article

Investigations on the Chemistry of Berbanes, XII. Synthesis of Pseudo‐Depyrroloyohimbine Analogues

Tóth, István, Bozsár, Gabriella, Szabó, Lajos, Baitz‐Gács, Eszter, Tamás, József and Szántay, Csaba (1987). Investigations on the Chemistry of Berbanes, XII. Synthesis of Pseudo‐Depyrroloyohimbine Analogues. Liebigs Annalen der Chemie, 1987 (3), 243-247. doi: 10.1002/jlac.198719870315

Investigations on the Chemistry of Berbanes, XII. Synthesis of Pseudo‐Depyrroloyohimbine Analogues

1984

Journal Article

Investigations On the Chemistry of Berbanes .10. Synthesis of Raunescinone Analogs with Hypotensive and Antihypertensive Activity

Toth, I, Szabo, L, Bozsar, G, Szantay, C, Szekeres, L and Papp, JG (1984). Investigations On the Chemistry of Berbanes .10. Synthesis of Raunescinone Analogs with Hypotensive and Antihypertensive Activity. Journal of Medicinal Chemistry, 27 (11), 1411-1415. doi: 10.1021/jm00377a006

Investigations On the Chemistry of Berbanes .10. Synthesis of Raunescinone Analogs with Hypotensive and Antihypertensive Activity

1983

Journal Article

EFFECT OF THIOCARBAMATE HERBICIDES ON THE MEMBRANE-STRUCTURE AND TRANSPORT PROCESSES OF THE RICE ROOT

TOTH, and TOTH, M (1983). EFFECT OF THIOCARBAMATE HERBICIDES ON THE MEMBRANE-STRUCTURE AND TRANSPORT PROCESSES OF THE RICE ROOT. Botanikai Kozlemenyek-Botanical Publications, 70 (3-4), 139-149.

EFFECT OF THIOCARBAMATE HERBICIDES ON THE MEMBRANE-STRUCTURE AND TRANSPORT PROCESSES OF THE RICE ROOT

1982

Journal Article

Lipidic peptides. XI. Quantitative structure-activity relationships of a series of lipidic amino acid conjugates of β-lactam antibiotics

Valko, K, Toth, I, Ward, P, Slegel, P and Gibbons, WA (1982). Lipidic peptides. XI. Quantitative structure-activity relationships of a series of lipidic amino acid conjugates of β-lactam antibiotics. International Journal of Pharmaceutics, 83 (1-3), 123-130. doi: 10.1016/0378-5173(82)90014-X

Lipidic peptides. XI. Quantitative structure-activity relationships of a series of lipidic amino acid conjugates of β-lactam antibiotics

1979

Journal Article

Synthesis of Benzo[A]Quinolizidine Derivatives Showing Anti-Inflammatory Activity Without Ulcerogen Side-Effect

Szabo, L, Nogradi, K, Toth, I, Szantay, C, Radics, L, Virag, S and Kanyo, E (1979). Synthesis of Benzo[A]Quinolizidine Derivatives Showing Anti-Inflammatory Activity Without Ulcerogen Side-Effect. Acta Chimica Academiae Scientarium Hungaricae, 100 (1-4), 19-36.

Synthesis of Benzo[A]Quinolizidine Derivatives Showing Anti-Inflammatory Activity Without Ulcerogen Side-Effect

1979

Journal Article

Investigation On the Chemistry of Berbans .8. Synthesis of Inside Depyrrolo-Yohimbine Analogs

Toth, I, Szabo, L, Tamas, J and Szantay, C (1979). Investigation On the Chemistry of Berbans .8. Synthesis of Inside Depyrrolo-Yohimbine Analogs. Tetrahedron, 35 (17), 2043-2047. doi: 10.1016/S0040-4020(01)88976-6

Investigation On the Chemistry of Berbans .8. Synthesis of Inside Depyrrolo-Yohimbine Analogs

1979

Journal Article

Approaches to triterpene synthesis. Methyl group migration during catalytic hydrogenation of some precursors

Apsimon, JW and Toth, I (1979). Approaches to triterpene synthesis. Methyl group migration during catalytic hydrogenation of some precursors. Journal of the Chemical Society-Chemical Communications (2), 67-67. doi: 10.1039/C39790000067

Approaches to triterpene synthesis. Methyl group migration during catalytic hydrogenation of some precursors

1979

Journal Article

Synthesis of benzo[a]quinolizidine derivatives showing antiinflammatory activity without ulcerogen side effect

Szabo, L., Nogradi, K. and Toth, I. (1979). Synthesis of benzo[a]quinolizidine derivatives showing antiinflammatory activity without ulcerogen side effect. Acta Chimica Academiae Scientiarum Hungaricae, 100 (1-4), 19-36.

Synthesis of benzo[a]quinolizidine derivatives showing antiinflammatory activity without ulcerogen side effect

1978

Journal Article

Investigation On Chemistry of Berbans .7. Synthesis of 10,11-Dimethoxy(Depyrrolo)Raunescine Stereoisomers

Toth, I, Szabo, L, Kajtarperedi, M, Baitzgacs, E, Radics, L and Szantay, C (1978). Investigation On Chemistry of Berbans .7. Synthesis of 10,11-Dimethoxy(Depyrrolo)Raunescine Stereoisomers. Tetrahedron, 34 (14), 2113-2122. doi: 10.1016/0040-4020(78)89011-5

Investigation On Chemistry of Berbans .7. Synthesis of 10,11-Dimethoxy(Depyrrolo)Raunescine Stereoisomers

1977

Journal Article

Investigations On Chemistry of Berbans .5. Synthesis of 18-Acyloxy-10,11-Dimethoxy-(Depyrrolo)Alloyohimbinones

Szabo, L, Toth, I, Toke, L and Szantay, C (1977). Investigations On Chemistry of Berbans .5. Synthesis of 18-Acyloxy-10,11-Dimethoxy-(Depyrrolo)Alloyohimbinones. Justus Liebigs Annalen der Chemie (4), 634-641.

Investigations On Chemistry of Berbans .5. Synthesis of 18-Acyloxy-10,11-Dimethoxy-(Depyrrolo)Alloyohimbinones

1977

Journal Article

Untersuchungen über Verbindungen mit Berban‐Gerüst, V. Über die Synthese von 18‐Acyloxy‐10,11‐dimethoxy(despyrrolo)‐alloyohimbinone

Szabó, Lajos, Tóth, István, Tőke, László and Szántay, Csaba (1977). Untersuchungen über Verbindungen mit Berban‐Gerüst, V. Über die Synthese von 18‐Acyloxy‐10,11‐dimethoxy(despyrrolo)‐alloyohimbinone. Justus Liebigs Annalen der Chemie, 1977 (4), 634-641. doi: 10.1002/jlac.197719770414

Untersuchungen über Verbindungen mit Berban‐Gerüst, V. Über die Synthese von 18‐Acyloxy‐10,11‐dimethoxy(despyrrolo)‐alloyohimbinone

1977

Journal Article

Untersuchungen über Verbindungen mit Berban‐Gerüst, VI. Neue Synthese von 10‐Methoxy(despyrrolo)reserpin und seinen Stereoisomeren

Szabó, Lajos, Tóth, István, Tőke, László, Szántay, Csaba and Tamás, József (1977). Untersuchungen über Verbindungen mit Berban‐Gerüst, VI. Neue Synthese von 10‐Methoxy(despyrrolo)reserpin und seinen Stereoisomeren. Justus Liebigs Annalen der Chemie, 1977 (4), 642-663. doi: 10.1002/jlac.197719770415

Untersuchungen über Verbindungen mit Berban‐Gerüst, VI. Neue Synthese von 10‐Methoxy(despyrrolo)reserpin und seinen Stereoisomeren

1977

Journal Article

Investigations On Chemistry of Berbans .6. New Synthesis of 10-Methoxy(Depyrrolo)-Reserpine and its Stereoisomers

Szabo, L, Toth, I, Toke, L, Szantay, C and Tamas, J (1977). Investigations On Chemistry of Berbans .6. New Synthesis of 10-Methoxy(Depyrrolo)-Reserpine and its Stereoisomers. Justus Liebigs Annalen der Chemie (4), 642-663.

Investigations On Chemistry of Berbans .6. New Synthesis of 10-Methoxy(Depyrrolo)-Reserpine and its Stereoisomers

1976

Journal Article

Investigation On Chemistry of Berbans .4. Synthesis of Halogen Containing Depyrroloyohimbon Derivatives with Pg-Like and Pg-Antagonistic Effect

Szabo, L, Toth, I, Toke, L, Kolonits, P and Szantay, C (1976). Investigation On Chemistry of Berbans .4. Synthesis of Halogen Containing Depyrroloyohimbon Derivatives with Pg-Like and Pg-Antagonistic Effect. Chemische Berichte-Recueil, 109 (10), 3390-3403. doi: 10.1002/cber.19761091017

Investigation On Chemistry of Berbans .4. Synthesis of Halogen Containing Depyrroloyohimbon Derivatives with Pg-Like and Pg-Antagonistic Effect

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Emeritus Professor Istvan Toth directly for media enquiries about:

  • Chemistry - lipid
  • Chemistry - medicinal
  • Chemistry - peptide
  • Chemistry - sugar
  • Drug - oral administration
  • Drug delivery
  • Genes and vaccines
  • Immunisation
  • Lipid chemistry
  • Medicinal chemistry
  • Oral administration of vaccines
  • Peptide chemistry
  • Peptide drug delivery
  • Sugar chemistry
  • Vaccines - oral administration
  • Vaccines and genes

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