Emeritus Professor Istvan Toth
Emeritus Professor

Istvan Toth

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Background

Professor István Tóth is Chair in Biological Chemistry at The University of Queensland (UQ), Brisbane, Australia, and Affiliated Professorial Research Fellow at the Institute of Molecular Biosciences, UQ. He graduated with a degree in Chemical Engineering from the Technical University, Budapest, Hungary and was awarded his PhD for his Alkaloid Chemistry research. Professor Tóth undertook a postdoctoral fellowship at Carleton University, Ottawa Canada before returning to Hungary to work as a Research Associate, then Scientific Group Leader at the Central Research Institute for Chemistry, Hungarian Academy of Science. He joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 and was awarded a Doctor of Science degree (DSc 1994) for his work in Drug Delivery (Hungarian Academy of Sciences), before relocating to the University of Queensland in 1998 where he has built a productive research group. Professor Tóth was a visiting professor at the School of Pharmacy, University of London (1994-2004) and at the Department of Bioengineering and Therapeutic Science, University of California, San Francisco (2011-2013). Professor Tóth’s major research interests are: drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides, and nucleotides. This research has attracted over $85 million in competitive grants, research contracts and investment funds in the past 10 years. Professor Tóth has over 500 peer-reviewed publications, 45 patents, and an excellent track record in research commercialisation. He is a one of key founders of Alchemia, Implicit Bioscience Pty Ltd, Neurotide Pty Ltd and TetraQ (the commercial arm of Centre of Integrated Preclinical Drug Development). Professor Tóth is an elected RACI Fellow and Fellow of the Queensland Academy of Arts and Sciences. and Feklloiw of the Hungarian Academy of Sciences (since 2016) In 2009 he was awarded the Adrian Albert award for sustained and outstanding research in medicinal biochemistry, and a Business/Higher Education Round Table (BHERT) Award for Outstanding Achievement in International Collaborative Research and Development he obtained the Doctor Honoris Causa degree at Semmelweis university budapest Hungary (2019). Professor Tóth was appointed as a member of the ARC College of Experts (2008-2010). He was the founding (2007) then the elected (2008-2009) President of the Australian Chapter of Controlled Release Society.

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision
Media expert

Fields of research

Medicinal and biomolecular chemistry Organic chemistry

Qualifications

  • Doctor of Philosophy of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics
  • Doctoral Diploma of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics

Search Professor Istvan Toth’s works on UQ eSpace

683 works between 1972 and 2025
All (683) Journal Article (480) Book Chapter (42) Conference Publication (151) Book (3) Other Outputs (6) Edited Outputs (1)

581 - 600 of 683 works

1999

Journal Article

Lipoamino acid based glycolipids for drug delivery

Falconer, R. A., Florence, A. T. and Toth, I. (1999). Lipoamino acid based glycolipids for drug delivery. Journal of Pharm.Pharmacol., 51 (51), 335.

Lipoamino acid based glycolipids for drug delivery

1999

Conference Publication

Oral absorption of nanoparticles & dendrimers: facts & promise

Florence, A. T., Sakthivel, T., Carreno-Gomez, B. and Toth, I. (1999). Oral absorption of nanoparticles & dendrimers: facts & promise. 9th International symposium on recent advances in drug delivery, Salt Lake City, USA, 22-25 Feb 1999.

Oral absorption of nanoparticles & dendrimers: facts & promise

1999

Journal Article

Novel lipoamino acid & liposaccharide based system for peptide delivery: application for administering tumour selective somatostatin analogues

Toth, I., Malkinson, J. P., Flinn, N. S., Drouillat, B., Artursson, P. M. D. and Keri, G. (1999). Novel lipoamino acid & liposaccharide based system for peptide delivery: application for administering tumour selective somatostatin analogues. Journal of Medicinal Chemistry, 42 (42), 4010-4013. doi: 10.1021/jm9910167

Novel lipoamino acid & liposaccharide based system for peptide delivery: application for administering tumour selective somatostatin analogues

1999

Conference Publication

Synthesis of amphipathic lipoamino acid-based glycoconjugates PA061, 199

Falconer, R. A. and Toth, I. (1999). Synthesis of amphipathic lipoamino acid-based glycoconjugates PA061, 199. 10th European Carbohydrate Symposium, Galway, Ireland, 11-16 July 1999. Galway, Ireland: National Univ. of Ireland, Galway.

Synthesis of amphipathic lipoamino acid-based glycoconjugates PA061, 199

1999

Journal Article

Novel cationic lipidic peptide dendrimer vectors in vitro gene delivery

Toth, I., Sakthivel, T., Wilderspin, A. F., Bayele, H., O'Donnell, M., Perry, D. J., Pasi, K. J., Lee, C. A. and Florence, A. T. (1999). Novel cationic lipidic peptide dendrimer vectors in vitro gene delivery. S.T.P. Pharma Sciences, 9 (1), 93-99.

Novel cationic lipidic peptide dendrimer vectors in vitro gene delivery

1999

Journal Article

Efficient synthesis of thioglycosides via a Mitsunobu condensation.

Falconer, R. A., Jablonkai, I. and Toth, I. (1999). Efficient synthesis of thioglycosides via a Mitsunobu condensation.. Tetrahedron Letters, 40 (40), 8663-8666. doi: 10.1016/S0040-4039(99)01834-1

Efficient synthesis of thioglycosides via a Mitsunobu condensation.

1999

Conference Publication

Novel liposaccharide based drug & peptide delivery systems

Toth, I., Wright, K., Flinn, N. S., Malkinson, J. P. and Falconer, R. A. (1999). Novel liposaccharide based drug & peptide delivery systems. European Peptide Conference, Budapest, Hungary, 30 Aug-4 Sept, 1998. Budapest: Academiai Kiado.

Novel liposaccharide based drug & peptide delivery systems

1999

Journal Article

Investigation of transfection & cell viability using high concentrations of lipidic dendrimeric lysine.

Shah, D. S., Sakthivel, T., Toth, I., Florence, A. T. and Wilderspin, A. F. (1999). Investigation of transfection & cell viability using high concentrations of lipidic dendrimeric lysine.. Journal of Pharm.Pharmacol., 51 (51), 138.

Investigation of transfection & cell viability using high concentrations of lipidic dendrimeric lysine.

1999

Conference Publication

Solid phase synthesis of C-terminal glycopeptides via a modified Staudinger reaction

Malkinson, J. P., Falconer, R. A. and Toth, I. (1999). Solid phase synthesis of C-terminal glycopeptides via a modified Staudinger reaction. 10th European Carbohydrate Symposium, Galway, Ireland, 11-16 July 1999. Galway, Ireland:

Solid phase synthesis of C-terminal glycopeptides via a modified Staudinger reaction

1999

Journal Article

Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration

Sakthivel, T., Toth , I. and Florence, A. T. (1999). Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration. International Journal of Pharmaceutics, 183 (183), 51-55. doi: 10.1016/S0378-5173(99)00043-5

Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration

1999

Conference Publication

Novel liposaccharide conjugates for drug/peptide delivery & enhancing synthetic peptide immunogenicity

Toth, I. (1999). Novel liposaccharide conjugates for drug/peptide delivery & enhancing synthetic peptide immunogenicity. Australian Pharmaceutical Sciences Assoc. 1999 Annual Conf., Fremantle, WA, 28 Nov-1 Dec, 1999. Perth, WA: Curtin Uni.of Technology.

Novel liposaccharide conjugates for drug/peptide delivery & enhancing synthetic peptide immunogenicity

1999

Conference Publication

Lipid dendrimers: Oral absorption and distribution

Florence, A. T., Sakthivel, T. and Toth, I. (1999). Lipid dendrimers: Oral absorption and distribution.

Lipid dendrimers: Oral absorption and distribution

1999

Journal Article

Lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues

Artursson, P., Keri, G., Malkinson, J. P. and Toth, I. (1999). Lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues. Journal of pharmacy and pharmacology, 51 (51), 299.

Lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues

1999

Conference Publication

Novel lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues

Malkinson, J. P., Keri, G., Artursson, P. and Toth, I. (1999). Novel lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues. 16TH American Peptide Symposium, Minnesota, USA, 27 June - 1 July 1999. Menneapolis, USA: American Peptide Society.

Novel lipoamino acid & liposaccharide based peptide delivery system for tumour selective somatostatin analogues

1998

Journal Article

Partial inhibition of amplifications by primers of EHEC genes

Gadó, I., Ruzsics, Zs, Tóth, I., Király, Margit and Milch, Hedda (1998). Partial inhibition of amplifications by primers of EHEC genes. Acta Microbiologica et Immunologica Hungarica, 45 (2), 239-252.

Partial inhibition of amplifications by primers of EHEC genes

1998

Journal Article

Preparation and characterization of an IgG-dehydroepiandrosterone conjugate

Kittivoravitkul, Sasitorn, Flinn, Nicholas S., Toth, Istvan and Gregoriadis, Gregory (1998). Preparation and characterization of an IgG-dehydroepiandrosterone conjugate. Journal of Pharmacy and Pharmacology, 50 (SUPPL. 9), 243-243. doi: 10.1111/j.2042-7158.1998.tb02443.x

Preparation and characterization of an IgG-dehydroepiandrosterone conjugate

1998

Journal Article

Synthetic bicyclic analogues of quassinoids

Lang'at, Caroline C., Watt, Robert A., Toth, Istvan and Phillipson, J. David (1998). Synthetic bicyclic analogues of quassinoids. Tetrahedron, 54 (24), 6857-6866. doi: 10.1016/S0040-4020(98)00368-8

Synthetic bicyclic analogues of quassinoids

1998

Journal Article

Semisynthetic derivatives of quassin

Lang'at, Caroline C., Watt, Robert A., Toth, Istvan and Phillipson, J. David (1998). Semisynthetic derivatives of quassin. Tetrahedron, 54 (24), 6841-6856. doi: 10.1016/S0040-4020(98)00367-6

Semisynthetic derivatives of quassin

1998

Journal Article

Synthesis and physicochemical properties of lipophilic polyamide dendrimers

Sakthivel, T, Toth, I and Florence, AT (1998). Synthesis and physicochemical properties of lipophilic polyamide dendrimers. Pharmaceutical Research, 15 (5), 776-782. doi: 10.1023/A:1011935406664

Synthesis and physicochemical properties of lipophilic polyamide dendrimers

1998

Journal Article

Lipoamino acid conjugates of methotrexate with antitumor activity

Pignatello, R, Jansen, G, Kathmann, I, Puglisi, G and Toth, I (1998). Lipoamino acid conjugates of methotrexate with antitumor activity. Journal of Pharmaceutical Sciences, 87 (3), 367-371. doi: 10.1021/js970194p

Lipoamino acid conjugates of methotrexate with antitumor activity

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Emeritus Professor Istvan Toth directly for media enquiries about:

  • Chemistry - lipid
  • Chemistry - medicinal
  • Chemistry - peptide
  • Chemistry - sugar
  • Drug - oral administration
  • Drug delivery
  • Genes and vaccines
  • Immunisation
  • Lipid chemistry
  • Medicinal chemistry
  • Oral administration of vaccines
  • Peptide chemistry
  • Peptide drug delivery
  • Sugar chemistry
  • Vaccines - oral administration
  • Vaccines and genes

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