Emeritus Professor Istvan Toth
Emeritus Professor

Istvan Toth

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Background

Professor István Tóth is Chair in Biological Chemistry at The University of Queensland (UQ), Brisbane, Australia, and Affiliated Professorial Research Fellow at the Institute of Molecular Biosciences, UQ. He graduated with a degree in Chemical Engineering from the Technical University, Budapest, Hungary and was awarded his PhD for his Alkaloid Chemistry research. Professor Tóth undertook a postdoctoral fellowship at Carleton University, Ottawa Canada before returning to Hungary to work as a Research Associate, then Scientific Group Leader at the Central Research Institute for Chemistry, Hungarian Academy of Science. He joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 and was awarded a Doctor of Science degree (DSc 1994) for his work in Drug Delivery (Hungarian Academy of Sciences), before relocating to the University of Queensland in 1998 where he has built a productive research group. Professor Tóth was a visiting professor at the School of Pharmacy, University of London (1994-2004) and at the Department of Bioengineering and Therapeutic Science, University of California, San Francisco (2011-2013). Professor Tóth’s major research interests are: drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides, and nucleotides. This research has attracted over $85 million in competitive grants, research contracts and investment funds in the past 10 years. Professor Tóth has over 500 peer-reviewed publications, 45 patents, and an excellent track record in research commercialisation. He is a one of key founders of Alchemia, Implicit Bioscience Pty Ltd, Neurotide Pty Ltd and TetraQ (the commercial arm of Centre of Integrated Preclinical Drug Development). Professor Tóth is an elected RACI Fellow and Fellow of the Queensland Academy of Arts and Sciences. and Feklloiw of the Hungarian Academy of Sciences (since 2016) In 2009 he was awarded the Adrian Albert award for sustained and outstanding research in medicinal biochemistry, and a Business/Higher Education Round Table (BHERT) Award for Outstanding Achievement in International Collaborative Research and Development he obtained the Doctor Honoris Causa degree at Semmelweis university budapest Hungary (2019). Professor Tóth was appointed as a member of the ARC College of Experts (2008-2010). He was the founding (2007) then the elected (2008-2009) President of the Australian Chapter of Controlled Release Society.

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision
Media expert

Fields of research

Medicinal and biomolecular chemistry Organic chemistry

Qualifications

  • Doctor of Philosophy of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics
  • Doctoral Diploma of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics

Search Professor Istvan Toth’s works on UQ eSpace

683 works between 1972 and 2025
All (683) Journal Article (480) Book Chapter (42) Conference Publication (151) Book (3) Other Outputs (6) Edited Outputs (1)

521 - 540 of 683 works

2001

Conference Publication

Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity.

Toth, I., Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P. F., Adams, D. J. and Good, M. F. (2001). Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity.. 2nd International & 17th American Peptide Symposium, San Diego, California, US, 9-14 June, 2001. San Diego, CA: American Peptide Society.

Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity.

2001

Journal Article

Structural effects of lipophilic methotrexate conjugates on model phospholipid biomembranes

Pignatello, R., Toth, I. and Puglisi, G. (2001). Structural effects of lipophilic methotrexate conjugates on model phospholipid biomembranes. Thermochimica Acta, 380 (2), 255-264. doi: 10.1016/S0040-6031(01)00679-7

Structural effects of lipophilic methotrexate conjugates on model phospholipid biomembranes

2001

Book Chapter

Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity

Toth, Istvan, McGeary, Ross, Blanchfield, Joanne, Rhee, Handoo, Alewood, Paul, Adams, David and Good, Michael (2001). Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity. Peptides: The Wave of the Future. (pp. 937-939) edited by Michal Lebl and Richard A. Houghten. Dordrecht, Netherlands: Springer Netherlands. doi: 10.1007/978-94-010-0464-0_437

Liposaccharides: Utilisation for peptide delivery and for enhancing synthetic peptide immunogenicity

2001

Conference Publication

Lipoamino acid and liposaccharide conjugated peptides: Enhancement of bioavailability.

Chan, Y., Wong, A. K. and Toth, I. (2001). Lipoamino acid and liposaccharide conjugated peptides: Enhancement of bioavailability.. 2nd International Peptide Symposium & 17th American Peptide Symposium, San Diego, California, 9-14 June 2001. California: American Peptide Society.

Lipoamino acid and liposaccharide conjugated peptides: Enhancement of bioavailability.

2001

Conference Publication

Synthesis of lipo- and liposaccharide a-conotoxin MII conjugates.

Blanchfield, J. T., Dutton, J. L., Craik, D. J., Alewood, P.F., Lewis, R. J., Adams, D. J. and Toth, I. (2001). Synthesis of lipo- and liposaccharide a-conotoxin MII conjugates.. APSA Annual Conference 2001, Melbourne, Australia, 9-12 December, 2001. Melbourne, Australia: Australasian Pharmaceutical Science Association.

Synthesis of lipo- and liposaccharide a-conotoxin MII conjugates.

2001

Conference Publication

Lipids and sugars: Application for peptide delivery and for enhancing synthetic peptide immunogenicity

Toth, I., Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P.F. and Good, M. F. (2001). Lipids and sugars: Application for peptide delivery and for enhancing synthetic peptide immunogenicity. 4th Australian Peptide Conference, Lindeman Is., Queensland, 7-12 Oct 2001.

Lipids and sugars: Application for peptide delivery and for enhancing synthetic peptide immunogenicity

2001

Book Chapter

Lipoamino Acid and Liposaccharide Conjugated Peptides: Enhancement of Bioavailability

Chan, Yiu-Ngok, Wong, Allan K. and Toth, Istvan (2001). Lipoamino Acid and Liposaccharide Conjugated Peptides: Enhancement of Bioavailability. Peptides: The Wave of the Future. (pp. 955-956) Dordrecht, The Netherlands: Springer Netherlands. doi: 10.1007/978-94-010-0464-0_445

Lipoamino Acid and Liposaccharide Conjugated Peptides: Enhancement of Bioavailability

2001

Conference Publication

Synthetic vaccines containing multiple copies of group A streptococcus peptide epitopes.

Mcgeary, R. P., Schubert, A., Olive, C., Hayman, W., Good, M. F. and Toth, I. (2001). Synthetic vaccines containing multiple copies of group A streptococcus peptide epitopes.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Synthetic vaccines containing multiple copies of group A streptococcus peptide epitopes.

2001

Conference Publication

Synthetic vaccines built on carbohydrate cores

Mcgeary, R. P. and Toth, I. (2001). Synthetic vaccines built on carbohydrate cores. 4th Australian Peptide Conference, Lindeman Is., Qld, 7-12 Oct 2001. Australian Peptide Society.

Synthetic vaccines built on carbohydrate cores

2001

Conference Publication

Solid-phase synthesis of oligosaccharides utilising a novel Dde-based linker

Moyle, P.M., Mcgeary, R. P. and Toth, I. (2001). Solid-phase synthesis of oligosaccharides utilising a novel Dde-based linker. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

Solid-phase synthesis of oligosaccharides utilising a novel Dde-based linker

2001

Conference Publication

C-linked sugar - lipoamino acid conjugates

Falconer, R. A. and Toth, I. (2001). C-linked sugar - lipoamino acid conjugates. 26th European Peptide Conference, Montpellier, France, 10-15 Sept 2000. Paris, France: EDK.

C-linked sugar - lipoamino acid conjugates

2001

Journal Article

Conversion of glucosamine to galactosamine and allosamine derivatives: Control of inversions of stereochemistry at C-3 and C-4

McGeary, R. P., Wright, K. and Toth, I. (2001). Conversion of glucosamine to galactosamine and allosamine derivatives: Control of inversions of stereochemistry at C-3 and C-4. Journal of Organic Chemistry, 66 (15), 5102-5105. doi: 10.1021/jo010210+

Conversion of glucosamine to galactosamine and allosamine derivatives: Control of inversions of stereochemistry at C-3 and C-4

2001

Other Outputs

Protected aminosugars

Toth, I., Dekany, G. and Kellam, B. (2001). Protected aminosugars. 730910.

Protected aminosugars

2001

Conference Publication

Lipid-core-peptides for vaccination: A structure-activity relationship study.

Olive, C., Schubert, A., Wong, A. K., Good, M. F. and Toth, I. (2001). Lipid-core-peptides for vaccination: A structure-activity relationship study.. 4th Australian Peptide Conference, Lindeman Island, Qld., 7-12 Oct 2001.

Lipid-core-peptides for vaccination: A structure-activity relationship study.

2001

Conference Publication

The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.

Blanchfield, J. T., Rhee, H. and Toth, I. (2001). The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.. Brisbane Biological & Organic Chemistry Symposium 2001, University of Queensland, Brisbane, 30 Nov 2001. Brisbane:

The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.

2001

Journal Article

Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.

Olive, C., Toth, I. and Jackson, D. (2001). Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.. Mini Reviews in Medicinal Chemistry, 1 (4), 429-438. doi: 10.2174/1389557013406666

Technological advances in antigen delivery and synthetic peptide vaccine developmental strategies.

2001

Conference Publication

The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.

Blanchfield, J. T., Rhee, H. and Toth, I. (2001). The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.. APSA Annual Conference 2001, Melbourne, 9-12 Dec 2001. Melbourne: Australasian Pharmaceutical Science Association.

The synthesis and biological activity of an orally available liposaccharide analogue of LHRH.

2001

Conference Publication

Allosamines and galactosamines from glucosamine: Control of stereochemical inversions at C-3 and C-4.

Mcgeary, R. P., Wright, K. and Toth, I. (2001). Allosamines and galactosamines from glucosamine: Control of stereochemical inversions at C-3 and C-4.. Brisbane Biological and Organic Chemistry Symposium 2001, UQ, Brisbane, 30 Nov 2001. Brisbane:

Allosamines and galactosamines from glucosamine: Control of stereochemical inversions at C-3 and C-4.

2001

Conference Publication

Enhancing peptide delivery using lipoamino acids and liposaccharides.

Mcgeary, R. P., Blanchfield, J. T., Rhee, H., Alewood, P.F. and Toth, I. (2001). Enhancing peptide delivery using lipoamino acids and liposaccharides.. 7th International Symposium on Solid Phase Synthesis & Combinatorial Chemical Libraries, Southampton, UK, 18-22 Sept 2001. UK: European Peptide Society & BS/RSC Protein & Peptide Group, UK.

Enhancing peptide delivery using lipoamino acids and liposaccharides.

2001

Conference Publication

Determination of the transport across Caco-2 cell monolayers of compounds varying in lipophilicity using LC-MS

Wong, A. K., Ross, B. P., Artusson, P., Lazorova, L. and Toth, I. (2001). Determination of the transport across Caco-2 cell monolayers of compounds varying in lipophilicity using LC-MS. 26th European Peptide Conference, Montpellier, France, 10th - 15th September, 2000. Paris, France: EDK.

Determination of the transport across Caco-2 cell monolayers of compounds varying in lipophilicity using LC-MS

Current funding

  • 2024 - 2025
    Single-shot anti-fertility vaccine in pigs
    Australia's Economic Accelerator Seed Grants
    Open grant

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Emeritus Professor Istvan Toth directly for media enquiries about:

  • Chemistry - lipid
  • Chemistry - medicinal
  • Chemistry - peptide
  • Chemistry - sugar
  • Drug - oral administration
  • Drug delivery
  • Genes and vaccines
  • Immunisation
  • Lipid chemistry
  • Medicinal chemistry
  • Oral administration of vaccines
  • Peptide chemistry
  • Peptide drug delivery
  • Sugar chemistry
  • Vaccines - oral administration
  • Vaccines and genes

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