Emeritus Professor Istvan Toth
Emeritus Professor

Istvan Toth

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Background

Professor István Tóth is Chair in Biological Chemistry at The University of Queensland (UQ), Brisbane, Australia, and Affiliated Professorial Research Fellow at the Institute of Molecular Biosciences, UQ. He graduated with a degree in Chemical Engineering from the Technical University, Budapest, Hungary and was awarded his PhD for his Alkaloid Chemistry research. Professor Tóth undertook a postdoctoral fellowship at Carleton University, Ottawa Canada before returning to Hungary to work as a Research Associate, then Scientific Group Leader at the Central Research Institute for Chemistry, Hungarian Academy of Science. He joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 and was awarded a Doctor of Science degree (DSc 1994) for his work in Drug Delivery (Hungarian Academy of Sciences), before relocating to the University of Queensland in 1998 where he has built a productive research group. Professor Tóth was a visiting professor at the School of Pharmacy, University of London (1994-2004) and at the Department of Bioengineering and Therapeutic Science, University of California, San Francisco (2011-2013). Professor Tóth’s major research interests are: drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides, and nucleotides. This research has attracted over $85 million in competitive grants, research contracts and investment funds in the past 10 years. Professor Tóth has over 500 peer-reviewed publications, 45 patents, and an excellent track record in research commercialisation. He is a one of key founders of Alchemia, Implicit Bioscience Pty Ltd, Neurotide Pty Ltd and TetraQ (the commercial arm of Centre of Integrated Preclinical Drug Development). Professor Tóth is an elected RACI Fellow and Fellow of the Queensland Academy of Arts and Sciences. and Feklloiw of the Hungarian Academy of Sciences (since 2016) In 2009 he was awarded the Adrian Albert award for sustained and outstanding research in medicinal biochemistry, and a Business/Higher Education Round Table (BHERT) Award for Outstanding Achievement in International Collaborative Research and Development he obtained the Doctor Honoris Causa degree at Semmelweis university budapest Hungary (2019). Professor Tóth was appointed as a member of the ARC College of Experts (2008-2010). He was the founding (2007) then the elected (2008-2009) President of the Australian Chapter of Controlled Release Society.

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision
Media expert

Fields of research

Medicinal and biomolecular chemistry Organic chemistry

Qualifications

  • Doctor of Philosophy of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics
  • Doctoral Diploma of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics

Search Professor Istvan Toth’s works on UQ eSpace

683 works between 1972 and 2025
All (683) Journal Article (480) Book Chapter (42) Conference Publication (151) Book (3) Other Outputs (6) Edited Outputs (1)

561 - 580 of 683 works

2000

Conference Publication

Synthesis of glycopeptide modified IgE epitopes

Jablonkai, I. and Toth, I. (2000). Synthesis of glycopeptide modified IgE epitopes. 16th American Peptide Symposium, Minnesota, USA, 26 June-1 Jul. 2000. Dordrecht: Kluwer Academic.

Synthesis of glycopeptide modified IgE epitopes

2000

Conference Publication

A novel liposaccharide based system for peptide drug delivery

Blanchfield, J. T., Adams, D. J., Alewood, P. F., Lewis, R. J. and Toth, I. (2000). A novel liposaccharide based system for peptide drug delivery. The APSA 2000 Annual Conference, Newcastle, 6th - 8th December, 2000. Australia: APSA.

A novel liposaccharide based system for peptide drug delivery

2000

Conference Publication

Synthesis of glycopeptide modified IgE epitopes

Jablonkai, I and Toth, I (2000). Synthesis of glycopeptide modified IgE epitopes. 16th American Peptide Symposium, Minneapolis Mn, Jun 26-Jul 01, 1999. DORDRECHT: SPRINGER.

Synthesis of glycopeptide modified IgE epitopes

2000

Conference Publication

Synthesis of lipoamino acid and liposaccharide based peptides for enhancement of oral bioavailability

Chan, Y., Wong, A. K. and Toth, I. (2000). Synthesis of lipoamino acid and liposaccharide based peptides for enhancement of oral bioavailability. The First Brisbane Biological and Organic Chemistry Symposium, Griffith University, Brisbane, 27 November 2000. Brisbane, Australia: Griffith Unversity.

Synthesis of lipoamino acid and liposaccharide based peptides for enhancement of oral bioavailability

2000

Conference Publication

Synthesis of amphipathic glycolipids for drug delivery

Falconer, R. A. and Toth, I. (2000). Synthesis of amphipathic glycolipids for drug delivery. Millennial World Congress of Pharmaceutical Sciences, San Francisco, USA, 16-20 April 2000. San Francisco, USA: International Pharmaceutical Federation USA.

Synthesis of amphipathic glycolipids for drug delivery

2000

Journal Article

Synthesis of C-terminal glycopeptides from resin-bound glycosyl azides via a modified staudinger reaction

Malkinson, John P., Falconer, Robert A. and Toth, Istvan (2000). Synthesis of C-terminal glycopeptides from resin-bound glycosyl azides via a modified staudinger reaction. Journal of Organic Chemistry, 65 (17), 5249-5252. doi: 10.1021/jo000381z

Synthesis of C-terminal glycopeptides from resin-bound glycosyl azides via a modified staudinger reaction

2000

Conference Publication

A novel liposaccharide based system for peptide drug delivery

Adams, D. J., Alewood, P. F., Blanchfield, J. T., Lewis, R. J. and Toth, I. (2000). A novel liposaccharide based system for peptide drug delivery. The First Brisbane Biological and Organic Chemistry Symposium, Griffith University, Brisbane, 27 November. 2000.

A novel liposaccharide based system for peptide drug delivery

2000

Journal Article

Porcine postweaning diarrhea isolates of Escherichia coli with uropathogenic characters

Tóth, István, Oswald, Eric, Mainil, Jacques, Awad-Masalmeh, Mohamed and Nagy, Béla (2000). Porcine postweaning diarrhea isolates of Escherichia coli with uropathogenic characters. Advances in Experimental Medicine and Biology, 485, 331-334.

Porcine postweaning diarrhea isolates of Escherichia coli with uropathogenic characters

2000

Journal Article

Virulence markers of human uropathogenic Escherichia coli strains isolated in Hungary

Tóth, István, Oswald, Eric, Szabó, Béla, Barcs, István and Emődy, Levente (2000). Virulence markers of human uropathogenic Escherichia coli strains isolated in Hungary. Advances in Experimental Medicine and Biology, 485, 335-338.

Virulence markers of human uropathogenic Escherichia coli strains isolated in Hungary

2000

Conference Publication

Synthesis of C-linked lipoamino acid based glycolipids

Falconer, R. A. and Toth, I. (2000). Synthesis of C-linked lipoamino acid based glycolipids. 20th International Carbohydrate Symposium, Hamburg, Germany, 27 Aug - 1 Sep 2001. Hamburg: Carbohydrate Society.

Synthesis of C-linked lipoamino acid based glycolipids

2000

Journal Article

Synthesis of C-linked sugar-lipoamino acid conjugates

Falconer, R. A. and Toth, I. (2000). Synthesis of C-linked sugar-lipoamino acid conjugates. Journal of Peptide Science, 6, 106.

Synthesis of C-linked sugar-lipoamino acid conjugates

2000

Conference Publication

Lipoamino acid and liposaccharide based peptide delivery system

Chan, Y., Wong, A. K. and Toth, I. (2000). Lipoamino acid and liposaccharide based peptide delivery system. APSA 2000 Annual Conference, Newcastle, NSW, 6-8 December 2000. Brisbane, Australia: University of Qld.

Lipoamino acid and liposaccharide based peptide delivery system

2000

Conference Publication

Synthesis and characterisation of linear amphipathic lysine-lipid conjugates

Sakthivel, T., Yanai, S., Toth, I. and Florence, A. T. (2000). Synthesis and characterisation of linear amphipathic lysine-lipid conjugates. Millennial World Congress of Pharmaceutical Sciences, San Francisco, USA, 16-20 April 2000. San Francisco, USA: International Pharmaceutical Federation USA.

Synthesis and characterisation of linear amphipathic lysine-lipid conjugates

2000

Journal Article

Liposaccharide based peptide delivery system for tumour selective somatostatin analogues

Wong, A. K., Malkinson, J. P., Keri, G., Artursson, P. and Toth, I. (2000). Liposaccharide based peptide delivery system for tumour selective somatostatin analogues. Journal of Peptide Science, 6 (Supplement 1: 26th European Peptide Society Meeting), 109.

Liposaccharide based peptide delivery system for tumour selective somatostatin analogues

2000

Conference Publication

Novel lipoamino acid and liposaccharide based peptide delivery system for tumour selective somatostatin analogues

Malkinson, J. P., Keri, G., Artursson, P. and Toth, I. (2000). Novel lipoamino acid and liposaccharide based peptide delivery system for tumour selective somatostatin analogues. 16th American Peptide Symposium, Minnesota, USA, 26th June - 1 July, 1999. Dordrecht: Kluwer Academic.

Novel lipoamino acid and liposaccharide based peptide delivery system for tumour selective somatostatin analogues

2000

Conference Publication

Determination of the transport across CACO-2 cell monolayers of compounds varying in lipophilicity using LC-MS

Wong, A. K., Ross, B. P., Jones, A., Artursson, P., Lazorova, L. and Toth, I. (2000). Determination of the transport across CACO-2 cell monolayers of compounds varying in lipophilicity using LC-MS. APSA 2000 Annual Conference, Newcastle, 6-8 December, 2000. Australia: The University of Queensland.

Determination of the transport across CACO-2 cell monolayers of compounds varying in lipophilicity using LC-MS

1999

Journal Article

The formation of a paniculate delivery system using MG145-LCP

Fletcher, K., Florence, A. T., Gard, P. R., Hillery, A. M., Lloyd, A. W. and Toth, I. (1999). The formation of a paniculate delivery system using MG145-LCP. Journal of Pharmacy and Pharmacology, 51 (SUPPL.).

The formation of a paniculate delivery system using MG145-LCP

1999

Journal Article

Investigation of transfection & cell viability using high concentrations of lipidic dendrimeric lysine.

Shah, D. S., Sakthivel, T., Toth, I., Florence, A. T. and Wilderspin, A. F. (1999). Investigation of transfection & cell viability using high concentrations of lipidic dendrimeric lysine.. Journal of Pharm.Pharmacol., 51 (51), 138.

Investigation of transfection & cell viability using high concentrations of lipidic dendrimeric lysine.

1999

Conference Publication

Novel liposaccharide based drug & peptide delivery systems

Toth, I., Wright, K., Flinn, N. S., Malkinson, J. P. and Falconer, R. A. (1999). Novel liposaccharide based drug & peptide delivery systems. European Peptide Conference, Budapest, Hungary, 30 Aug-4 Sept, 1998. Budapest: Academiai Kiado.

Novel liposaccharide based drug & peptide delivery systems

1999

Journal Article

Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration

Sakthivel, T., Toth , I. and Florence, A. T. (1999). Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration. International Journal of Pharmaceutics, 183 (183), 51-55. doi: 10.1016/S0378-5173(99)00043-5

Distribution of a lipidic 2.5 nm diameter dendrimer carrier after oral administration

Current funding

  • 2024 - 2025
    Single-shot anti-fertility vaccine in pigs
    Australia's Economic Accelerator Seed Grants
    Open grant

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Emeritus Professor Istvan Toth directly for media enquiries about:

  • Chemistry - lipid
  • Chemistry - medicinal
  • Chemistry - peptide
  • Chemistry - sugar
  • Drug - oral administration
  • Drug delivery
  • Genes and vaccines
  • Immunisation
  • Lipid chemistry
  • Medicinal chemistry
  • Oral administration of vaccines
  • Peptide chemistry
  • Peptide drug delivery
  • Sugar chemistry
  • Vaccines - oral administration
  • Vaccines and genes

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