Overview
Background
Professor Khosrotehrani is a clinical scientist, dircetor of the Frazer institute, the university of Queensalnd, sharing his passion for academic medicine and translation of science discorveries into real world solutions for patients. Prof Khosrotehrani is a dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Frazer Institute within the Translational Research Institute in Brisbane, Australia. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.
As the inaugural St Baker-Soyer chair of Dermatology at the University of Queensland, Professor Khosrotehrani is a national leader in the discipline of Dermatology. He is a board director at the Australasian College of Dermatologists and the Queensland Skin and Cancer Foundation and the director of the Dermatology Department at the Princess Alexandra Hospital. He has held multiple leadership roles as past-President of the Australasian Society for Dermatology Research, Editor in chief of the Australasian Journal of Dermatology and board member of the International Society of investigative Dermatology.
During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Paris
Research interests
-
Tissue regeneration
Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.
-
Skin cancer
Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation
Works
Search Professor Kiarash Khosrotehrani’s works on UQ eSpace
2025
Journal Article
Sociodemographic disparities in melanoma stage at diagnosis: the role of socioeconomic status and residential location
Gavanescu, Danielle, Dobson, Annette, Sharma, Hansa, Tan, Samuel X., Muller, Nicholas M., Hughes, Maria Celia B., Malt, Maryrose K., Smithers, B. Mark, Khosrotehrani, Kiarash and von Schuckmann, Lena A. (2025). Sociodemographic disparities in melanoma stage at diagnosis: the role of socioeconomic status and residential location. Cancer Epidemiology, Biomarkers and Prevention, 34 (10), 1771-1775. doi: 10.1158/1055-9965.epi-25-0372
2025
Journal Article
Criteria for Commencing and Continuing Subsidised Janus Kinase Inhibitor Therapy in Australian Alopecia Areata Patients—Results From an Australian Expert Consensus Exercise
Thomas, Meryl, Hankins, Madeline, Darchini‐Maragheh, Emadodin, Bokhari, Laita, Eisman, Samantha, Yip, Leona, York, Katherine, Li, Jane, Sharma, Pooja, Triwongwaranat, Daranporn, Chitreddy, Vijaya, Ghiya, Ragini, Kushnir‐Grinbaum, Daniella, Frewen, John, Yong, Shin Shen, Rathnayake, Deepani, Cranwell, William, Wall, Dmitri, Varathan, Vanathy, Khosrotehrani, Kiarash, Orchard, David, Moussa, Anthony, Paranjape, Meghana and Sinclair, Rodney (2025). Criteria for Commencing and Continuing Subsidised Janus Kinase Inhibitor Therapy in Australian Alopecia Areata Patients—Results From an Australian Expert Consensus Exercise. Australasian Journal of Dermatology, 66 (7) ajd.14556, 404-412. doi: 10.1111/ajd.14556
2025
Conference Publication
Topical sirolimus prevents cutaneous squamous cell carcinomas by disrupting the balance between differentiation and proliferation
Dousset, L., Zhou, C., Kao, Y., Tan, S., Muller, N., Sormani, L., Cox, C., Soyer, H.P., Stark, M.S., Wong, H., Roy, E. and Khosrotehrani, K. (2025). Topical sirolimus prevents cutaneous squamous cell carcinomas by disrupting the balance between differentiation and proliferation. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.777
2025
Conference Publication
Spatial transcriptomics reveals molecular determinants of mortality in thin melanoma
Zhou, C., Tan, S.X., Kao, Y., Claeson, M., Brown, S., Lambie, D., Whiteman, D.C., Pandeya, N., Olsen, C.M., Barbour, A., MacGregor, S., Soyer, H.P., Stark, M.S., Hayward, N., Smithers, B.M., Nguyen, Q. and Khosrotehrani, K. (2025). Spatial transcriptomics reveals molecular determinants of mortality in thin melanoma. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.109
2025
Conference Publication
Epithelial-mesenchymal transition and immune exclusion underpin the natural history of primary cutaneous melanoma
Tan, S.X., Muller, N., Zhou, C., Vipulaguna, N., Kao, Y., Whiteman, D.C., Soyer, H.P., Stark, M.S., Nguyen, Q. and Khosrotehrani, K. (2025). Epithelial-mesenchymal transition and immune exclusion underpin the natural history of primary cutaneous melanoma. Society for Investigative Dermatology (SID) 2025 Meeting, San Diego, CA United States, 7-10 May 2025. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2025.06.953
2025
Other Outputs
Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types
Prakrithi, P., Grice, Laura F., Zhang, Feng, Hockey, Levi, Tan, Samuel X., Tan, Xiao, Xiong, Zherui, Mulay, Onkar, Causer, Andrew, Newman, Andrew, Pham, Duy, Ni, Guiyan, Tuong, Kelvin, Jin, Xinnan, Kim, Eunju, Tran, Minh, Vu, Hani, Muller, Nicholas M., Killingbeck, Emily E., Gregory, Mark T., Teoh, Siok Min, Vo, Tuan, Zhang, Min, Landi, Maria Teresa, Brown, Kevin M., Iles, Mark M., Reitz, Zachary, Devitt, Katharina, Pan, Liuliu ... Nguyen, Quan (2025). Integrating 12 Spatial and Single Cell Technologies to Characterise Tumour Neighbourhoods and Cellular Interactions in three Skin Cancer Types. doi: 10.1101/2025.07.25.666708
2025
Journal Article
Bigger might actually be better: A prospective investigation into the association between body mass index, tumour stage, and recurrence in patients with high-risk primary melanoma
Sharma, Hansa, Hughes, Maria Celia B., Gavanescu, Danielle, Malt, Maryrose, Smithers, B Mark, Khosrotehrani, Kiarash and von Schuckmann, Lena (2025). Bigger might actually be better: A prospective investigation into the association between body mass index, tumour stage, and recurrence in patients with high-risk primary melanoma. Journal of the American Academy of Dermatology, 93 (6), 1543-1545. doi: 10.1016/j.jaad.2025.07.043
2025
Journal Article
The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases
Dang, Thi Viet Trinh, Mehdi, Ahmed M., Kumari, Snehlata, Khosrotehrani, Kiarash, Frazer, Ian H., Hume, David A. and Chandra, Janin (2025). The Involvement of IL-34 in Inflammatory and Malignant Skin Diseases. Journal of Investigative Dermatology, 145 (11), 1-13. doi: 10.1016/j.jid.2025.05.003
2025
Conference Publication
The effects of body mass index and type 2 diabetes mellitus on melanoma prognosis in patients with high-risk primaries
Sharma, Hansa, Hughes, Maria Celia, Gavanescu, Danielle, Smithers, Mark, Khosrotehrani, Kiarash and Von Schuckmann, Lena (2025). The effects of body mass index and type 2 diabetes mellitus on melanoma prognosis in patients with high-risk primaries. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC 3121 Australia: John Wiley & Sons.
2025
Conference Publication
Can diet affect melanoma prognosis? An analysis of the healthy eating index and the mediterranean diet in patients with high-risk primary melanoma
Sharma, Hansa, Hughes, Maria Celia, Gavanescu, Danielle, Smithers, Mark, Khosrotehrani, Kiarash and Von Schuckmann, Lena (2025). Can diet affect melanoma prognosis? An analysis of the healthy eating index and the mediterranean diet in patients with high-risk primary melanoma. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Conference Publication
Outcomes of checkpoint inhibitors in kidney transplant recipients
Nam, Hyun Jae, Shao, Emily, Cao, Michael, Wong, Kennedy, Khosrotehrani, Kiarash, Isbel, Nicole, Campbell, Scott and Ladwa, Rahul (2025). Outcomes of checkpoint inhibitors in kidney transplant recipients. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Conference Publication
The first 1000 participants in the Australasian Dermatology Registry
Baker, Christopher, Lehmann, Chelsea, Armstrong, Julie, Anderson, Sue, Chan, Jonathan, Penas, Pablo Fernandez, Kern, Johannes S., Khosrotehrani, Kiarash, Sidhu, Shireen, Youssef, Peter and Foley, Peter (2025). The first 1000 participants in the Australasian Dermatology Registry. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Conference Publication
Can you see me? Development and validation of digital algorithms to identify hidradenitis suppurativa in Queensland
Liu, Timothy, Pham, Hai, Flores, Deborah Toledo, Khosrotehrani, Kiarash, Pole, Jason and McMeniman, Erin (2025). Can you see me? Development and validation of digital algorithms to identify hidradenitis suppurativa in Queensland. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Conference Publication
Ensemble machine learning informs risk of recurrence in primary cutaneous melanoma: a 7-year prospective cohort study
Tan, Samuel, Muller, Nicholas, Gavanescu, Danielle, Sharma, Hansa, Vipulaguna, Nisal, Smithers, Mark, Khosrotehrani, Kiarash and Von Schuckmann, Lena (2025). Ensemble machine learning informs risk of recurrence in primary cutaneous melanoma: a 7-year prospective cohort study. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Conference Publication
Association between occupational UV exposure and melanoma recurrence
Gavanescu, Danielle, Sharma, Hansa, Tan, Samuel, Muller, Nicholas, Von Schuckmann, Lena and Khosrotehrani, Kiarash (2025). Association between occupational UV exposure and melanoma recurrence. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Conference Publication
Thick versus thin: the natural history of primary melanoma is characterized by Mesenchymal transition and immune exclusion
Tan, Samuel, Muller, Nicholas, Zhou, Chenhao, Kao, Yung-Ching, Vipulaguna, Nisal, Gavanescu, Danielle, Roy, Edwige, Whiteman, David, Soyer, H. Peter, Stark, Mitchell, Nguyen, Quan and Khosrotehrani, Kiarash (2025). Thick versus thin: the natural history of primary melanoma is characterized by Mesenchymal transition and immune exclusion. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May 2025 – 2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Conference Publication
Implementation of a new teledermatology clinic
Stone, Corey, Kelly, Madeleine, Wu, Jason, Khosrotehrani, Kiarash and Soyer, H. Peter (2025). Implementation of a new teledermatology clinic. Australasian College of Dermatologists, 57th Annual Scientific Meeting, Brisbane, QLD, Australia, 31 May-2 June 2025. Richmond, VIC, Australia: John Wiley & Sons.
2025
Journal Article
Assessment of the Influence of <scp>UVR</scp> in Cutaneous Melanoma
Walker, Graeme J. and Khosrotehrani, Kiarash (2025). Assessment of the Influence of UVR in Cutaneous Melanoma. Photodermatology, Photoimmunology & Photomedicine, 41 (3) e70024, e70024. doi: 10.1111/phpp.70024
2025
Journal Article
Haematological cancers and skin cancer: statistics from the Netherlands
von Schuckmann, Lena A and Khosrotehrani, Kiarash (2025). Haematological cancers and skin cancer: statistics from the Netherlands. British Journal of Dermatology, 192 (6), 966-967. doi: 10.1093/bjd/ljaf081
2025
Journal Article
Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study
Tan, Samuel X., Muller, Nicholas, Zhou, Chenhao, Walpole, Euan, Smithers, B. Mark, Whiteman, David C. and Khosrotehrani, Kiarash (2025). Prognostic markers could extend adjuvant immunotherapy to high-risk Stage IB/IIA melanoma: a modelling study. JAAD International, 18, 86-87. doi: 10.1016/j.jdin.2024.09.010
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Master Philosophy
Skin micro-bio-tox: understanding the skin toxicity associated with immune checkpoint inhibitors
Principal Advisor
Other advisors: Dr Janin Chandra
-
Master Philosophy
Spatial omics to characterize the clinicopathologic subsets of melanoma
Principal Advisor
-
Doctor Philosophy
Evaluating the impact of social determinants of health on skin cancer outcomes
Principal Advisor
-
Doctor Philosophy
Understanding and targeting determinants of mortality from melanoma
Principal Advisor
Other advisors: Dr Quan Nguyen, Dr Lena Von Schuckmann
-
Doctor Philosophy
Spatial imaging to predict survival in melanoma
Principal Advisor
Other advisors: Dr Quan Nguyen
-
Doctor Philosophy
Understanding Melanoma Vascularisation to prevent metastasis
Associate Advisor
-
Doctor Philosophy
Understanding immune diversity in skin inflammation
Associate Advisor
Other advisors: Professor Gabrielle Belz, Dr Snehlata Kumari
-
Doctor Philosophy
Predictive and prognostic biomarkers for melanoma progression (BioMEL)
Associate Advisor
Other advisors: Associate Professor Mitchell Stark
-
Master Philosophy
Analysing the association between diet, comorbidities and melanoma prognosis in patients with high-risk primaries
Associate Advisor
Other advisors: Dr Lena Von Schuckmann
-
Doctor Philosophy
Characterizing the role of ion channel kinase in skin homeostasis
Associate Advisor
Other advisors: Professor Fiona Simpson, Dr Snehlata Kumari
-
Doctor Philosophy
Defining the role of non-immune MHCII expression in the development of squamous cell cancers.
Associate Advisor
Other advisors: Dr Debottam Sinha, Dr Janin Chandra
-
Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass, Dr Abbas Shafiee, Associate Professor Jason Lee
-
Doctor Philosophy
Novel genomic predictors of survival in thin and thick melanomas
Associate Advisor
Other advisors: Associate Professor Mitchell Stark
Completed supervision
-
2025
Master Philosophy
A Pilot Observational Study of Changes in Naevi during Pregnancy using Total-Body Imaging.
Principal Advisor
-
2024
Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
-
2024
Doctor Philosophy
Potency and activity of meso-endothelial bipotent progenitors in vivo in homeostasis and injury
Principal Advisor
Other advisors: Dr Simranpreet Kaur
-
2024
Doctor Philosophy
Identifying genetic and epigenetic regulators of skin and hair follicle physiology and disease in mice: A systems-based approach using The Collaborative Cross
Principal Advisor
Other advisors: Dr Sally Mortlock
-
-
2023
Doctor Philosophy
Deciphering the Influence of Macrophages on Endothelial Progenitors
Principal Advisor
Other advisors: Professor Allison Pettit, Dr Simranpreet Kaur, Professor Antje Blumenthal
-
-
2023
Doctor Philosophy
Investigating the contribution of vascular Sox9 to fibrosis in homeostasis and systemic sclerosis
Principal Advisor
Other advisors: Dr Simranpreet Kaur
-
2023
Master Philosophy
Mutation burden as a biomarker of keratinocyte cancer risk prediction and field treatment efficacy
Principal Advisor
-
2022
Doctor Philosophy
Uncovering the Role of Endovascular Progenitors in Melanoma Development and Metastatic Progression
Principal Advisor
-
2022
Doctor Philosophy
Defining endovascular progenitors in homeostasis and disease
Principal Advisor
-
2020
Master Philosophy
Predicting melanoma outcome using clinical and biological indicators
Principal Advisor
-
2019
Master Philosophy
Dissecting Molecular Events in Pregnancy-Associated Melanoma
Principal Advisor
-
2018
Doctor Philosophy
The Role of Skin Macrophages Under Conditions of Stress and Injury: Ultraviolet Irradiation and Wound Healing
Principal Advisor
-
2018
Master Philosophy
Understanding the differences between basal cell carcinoma subtypes at the genomic and transcriptomic level.
Principal Advisor
-
2017
Doctor Philosophy
Prognostic factors in early stage invasive cutaneous melanoma
Principal Advisor
-
2017
Doctor Philosophy
A Genome-wide Approach to Identify Genetic Determinants of Skin Wound Healing and Scar Formation.
Principal Advisor
-
2015
Master Philosophy
The influence of pregnancy, parity, and sex on melanoma prognosis
Principal Advisor
-
2015
Doctor Philosophy
Mesenchymal-Epidermal Interactions in Hair Follicle Cycling and Regeneration
Principal Advisor
-
2025
Master Philosophy
Antibody-mediated exacerbation of chronic wounds colonised with Pseudomonas aeruginosa
Associate Advisor
Other advisors: Associate Professor Timothy Wells
-
2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
Other advisors: Professor Mark Smithers
-
2018
Doctor Philosophy
The role of SOX7 transcription factor in early blood vessel development
Associate Advisor
-
2014
Doctor Philosophy
Immune mediators of alloreactive responses in allogeneic stem cell transplantation and in pregnancy-induced microchimerism
Associate Advisor
Other advisors: Honorary Professor Geoffrey Hill
-
2013
Doctor Philosophy
Endogenous stem cell behaviour in tissue repair: lessons from fetal microchimerism
Associate Advisor
Media
Enquiries
Contact Professor Kiarash Khosrotehrani directly for media enquiries about:
- basal cell carcinoma
- Dermatology
- Fetal stem cells
- Melanoma
- Skin cancer
- Skin wound healing
- squamous cell carcinoma
- Stem cells - fetal
- Stem cells - skin wound healing
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: