
Overview
Background
Professor Khosrotehrani is a clinical scientist, dermatologist, interested in skin biology, regenerative medicine and skin cancer. He leads the Experimental Dermatology Group at the University of Queensland Diamantina Institute within the Translational Research Institute in Brisbane, Australia. He is also the deputy director of the Australian Skin and Skin Cancer Research Centre in Brisbane. Dr Khosrotehrani obtained his MD from the Cochin-Port Royal School of Medicine at René Descartes University, Paris, France, where he specialized in Dermatology. He is a former graduate of the Ecole Normale Supérieure and the Institut Pasteur of Paris (Université Paris VI, Pierre et Marie Curie) where he obtained a PhD in Physiology and Physiopathology. He is a fellow of the Australian College of Dermatologists and a practising dermatologist at the Princess Alexandra Hospital, Prince Charles Hospital and the Skin and Cancer Foundation’s Queensland Institute of Dermatology.
During his post-doctoral training at Tufts-New England Medical Center, Boston, USA, Dr. Khosrotehrani helped establish the contribution of fetal stem cells to tissue repair by demonstrating their multipotent capacity with a specific potency towards the endothelial lineage. The originality of this work was acknowledged by the NHMRC through an achievement award (2011) and an NHMRC excellence award (2016). He is currently a fellow of the NHMRC of Australia. The main focus of his laboratory is on regenerative medicine and stem cell biology in particular in injury response in skin wounds and skin cancer and how these responses contribute to cancer initiation and progression. Translating his laboratory findings, Dr Khosrotehrani is leading innovative clinical trials in wound healing, keratinocyte cancers and melanoma.
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Paris
Research interests
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Tissue regeneration
Endogenous response to injury. Vascular and Epithelial repair in response to ischemia or wounding. Hair follicle biology, cycling and regeneration.
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Skin cancer
Factors determining melanoma survival. Basal Cell carcinoma formation and progression Squamous cell carcinoma formation and UV irradiation
Works
Search Professor Kiarash Khosrotehrani’s works on UQ eSpace
2015
Conference Publication
Immune cell infiltrate subtypes inform on melanoma survival in stage Ib and II melanomas
Rowe, C., Tang, F., Rodero, M., Malt, M., Lambie, D., Smithers, M., Green, A. and Khosrotehrani, K. (2015). Immune cell infiltrate subtypes inform on melanoma survival in stage Ib and II melanomas. Australasian College of Dermatologists 48th Annual Scientific Meeting, Adelaide, Australia, 16 May 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12337
2015
Conference Publication
A Genome-wide Approach to Identify Determinants of Skin Wound Healing
Baz, B., Patel, J., Ram, R., Morahan, G., Walker, G. and Khosrotehrani, K. (2015). A Genome-wide Approach to Identify Determinants of Skin Wound Healing. 45th Annual Meeting of the European Society for Dermatological Research, Rotterdam, the Netherlands, 09-12 September 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/jid.2015.271
2014
Journal Article
In Vivo Imaging Reveals a Pioneer Wave of Monocyte Recruitment into Mouse Skin Wounds (vol 9, e108212, 2014)
Rodero, M. P., Licata, F., Poupel, L., Hamon, P. and Khosrotehrani, K. (2014). In Vivo Imaging Reveals a Pioneer Wave of Monocyte Recruitment into Mouse Skin Wounds (vol 9, e108212, 2014). Plos One, 9 (12) e115508, e115508. doi: 10.1371/journal.pone.0115508
2014
Journal Article
Concise review: understanding clonal dynamics in homeostasis and injury through multicolor lineage tracing
Roy, Edwige, Neufeld, Zoltan, Livet, Jean and Khosrotehrani, Kiarash (2014). Concise review: understanding clonal dynamics in homeostasis and injury through multicolor lineage tracing. Stem Cells, 32 (12), 3046-3054. doi: 10.1002/stem.1804
2014
Journal Article
Supportive care needs, anxiety, depression and quality of life amongst newly diagnosed patients with localised invasive cutaneous melanoma in Queensland, Australia
Beesley, Vanessa L., Smithers, B. Mark, Khosrotehrani, Kiarash, Khatun, Modsina, O'Rourke, Peter, Hughes, Maria Celia B., Malt, Maryrose K., Zonta, Mark J., Bayley, Gerard J., Barbour, Andrew P., Brown, Lee J., D'Arcy, Justin, Allan, Christopher and Green, Adèle C. (2014). Supportive care needs, anxiety, depression and quality of life amongst newly diagnosed patients with localised invasive cutaneous melanoma in Queensland, Australia. Psycho-Oncology, 24 (7), 763-770. doi: 10.1002/pon.3718
2014
Journal Article
In vivo imaging reveals a pioneer wave of monocyte recruitment into mouse skin wounds
Rodero, Mathieu P., Licata, Fabrice, Poupel, Lucie, Hamon, Pauline, Khosrotehrani, Kiarash, Combadiere, Christophe and Boissonnas, Alexandre (2014). In vivo imaging reveals a pioneer wave of monocyte recruitment into mouse skin wounds. PLoS One, 9 (10) e108212, e108212.1-e108212.9. doi: 10.1371/journal.pone.0108212
2014
Journal Article
In vitro pre-vascularisation of tissue-engineered constructs A co-culture perspective
Baldwin, Jeremy, Antille, Mélanie, Bonda, Ulrich, De-Juan-Pardo, Elena M., Khosrotehrani, Kiarash, Ivanovski, Saso, Petcu, Eugen Bogdan and Hutmacher, Dietmar Werner (2014). In vitro pre-vascularisation of tissue-engineered constructs A co-culture perspective. Vascular Cell, 6 (1) 13, 13.1-13.16. doi: 10.1186/2045-824X-6-13
2014
Journal Article
Transgenic flash mice for in vivo quantitative monitoring of canonical wnt signaling to track hair follicle cycle dynamics
Hodgson, Samantha S., Neufeld, Zoltan, Villani, Rehan M., Roy, Edwige and Khosrotehrani, Kiarash (2014). Transgenic flash mice for in vivo quantitative monitoring of canonical wnt signaling to track hair follicle cycle dynamics. Journal of Investigative Dermatology, 134 (6), 1519-1526. doi: 10.1038/jid.2014.92
2014
Journal Article
Nomograms to predict recurrence and survival in stage IIIB and IIIC melanoma after therapeutic lymphadenectomy
Khosrotehrani, Kiarash, van der Ploeg, Augustinus P.T., Siskind,Victor, Hughes, Maria Celia, Wright, Annaliesa, Thomas, Janine, Barbour, Andrew, Allan, Christopher, Bayley, Gerard, Eggermont, Alexander, Verhoef, Cornelis, Smithers, B. Mark and Green, Adele C. (2014). Nomograms to predict recurrence and survival in stage IIIB and IIIC melanoma after therapeutic lymphadenectomy. European Journal of Cancer, 50 (7), 1301-1309. doi: 10.1016/j.ejca.2014.02.010
2014
Journal Article
Biphasic recruitment of microchimeric fetal mesenchymal cells in fibrosis following acute kidney injury
Roy, Edwige, Seppanen, Elke, Ellis, Rebecca, Lee, Eddy S., Khosroterani, Kiarash, Fisk, Nicholas M. and Bou-Gharios, George (2014). Biphasic recruitment of microchimeric fetal mesenchymal cells in fibrosis following acute kidney injury. Kidney International, 85 (3), 600-610. doi: 10.1038/ki.2013.459
2014
Journal Article
Differential effects of ultraviolet irradiation in neonatal versus adult mice are not explained by defective macrophage or neutrophil infiltration.
Rodero, Mathieu P., Hokando, Herlina Y., Villani, Rehan M., Walker, Graeme J. and Khosrotehrani, Kiarash (2014). Differential effects of ultraviolet irradiation in neonatal versus adult mice are not explained by defective macrophage or neutrophil infiltration.. Journal of Investigative Dermatology, 134 (7), 1991-1997. doi: 10.1038/jid.2014.78
2014
Book Chapter
Microchimerism in Mouse Pregnancy
Nassar, Dany, Khosrotehrani, Kiarash and Aractingi, Selim (2014). Microchimerism in Mouse Pregnancy. The Guide to Investigation of Mouse Pregnancy. (pp. 251-258) Elsevier. doi: 10.1016/B978-0-12-394445-0.00021-7
2014
Conference Publication
A genome wide association study of survival in locally invasive melanoma
Rowe, C., Law, M., Palmer, J., MacGregor, S., Hayward, N. and Khosrotehrani, K. (2014). A genome wide association study of survival in locally invasive melanoma. 47th Annual Scientific Meeting, Melbourne, VIC Australia, 18-21 May 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12174
2014
Conference Publication
Melanoma prognosis differs according to sex: An Australian population study
Byrom, L., Dasgupta, P., Youlden, D., Baade, P., Green, A. and Khosrotehrani, K. (2014). Melanoma prognosis differs according to sex: An Australian population study. 47th Annual Scientific Meeting Conference, Melbourne, VIC Australia, 18-21 May 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12174
2014
Journal Article
Novel isolation strategy to deliver pure fetal-origin and maternal-origin mesenchymal stem cell (MSC) populations from human term placenta
Patel, J., Shafiee, A., Wang, W., Fisk, N. M. and Khosrotehrani, K. (2014). Novel isolation strategy to deliver pure fetal-origin and maternal-origin mesenchymal stem cell (MSC) populations from human term placenta. Placenta, 35 (11), 969-971. doi: 10.1016/j.placenta.2014.09.001
2014
Journal Article
Feto-maternal allo-immunity, regulatory T cells and predisposition to auto-immunity: does it all start in utero?
Leveque, Lucie and Khosrotehrani, Kiarash (2014). Feto-maternal allo-immunity, regulatory T cells and predisposition to auto-immunity: does it all start in utero?. Chimerism, 5 (2), 59-62. doi: 10.4161/chim.29844
2014
Conference Publication
Increased risk of melanoma mortality in pregnancy-associated tumours: A systematic review and meta-analysis
Byrom, L., Olsen, C., Knight, L., Khosrotehrani, K. and Green, A. C. (2014). Increased risk of melanoma mortality in pregnancy-associated tumours: A systematic review and meta-analysis. 47th Annual Scientific Meeting Conference, Melbourne, VIC Australia Conference, 18-21 May 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12174
2014
Journal Article
Multiple squamous cell carcinomas following introduction of nilotinib
Peters, P., Rabbolini, D., Sinnya, S., Khosrotehrani, K. and Wagner, G. (2014). Multiple squamous cell carcinomas following introduction of nilotinib. Clinical and Experimental Dermatology, 39 (7), 791-794. doi: 10.1111/ced.12388
2014
Conference Publication
Patients with a single invasive melanoma have a better prognosis than patients diagnosed with subsequent multiple melanomas
Rowe, C., Palmer, J., Hayward, N. and Khosrotehrani, K. (2014). Patients with a single invasive melanoma have a better prognosis than patients diagnosed with subsequent multiple melanomas. 47th Annual Scientific Meeting Conference, Melbourne, VIC Australia, 18-21 May 2014. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12174
2013
Journal Article
Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem cell transplantation
Andani, Rafiq, Robertson, Ivan, MacDonald, Kelli P. A., Durrant, Simon, Hill, Geoffrey R. and Khosrotehrani, Kiarash (2013). Origin of Langerhans cells in normal skin and chronic GVHD after hematopoietic stem cell transplantation. Experimental Dermatology, Accepted Article (1), 1-11. doi: 10.1111/exd.12301
Funding
Current funding
Past funding
Supervision
Availability
- Professor Kiarash Khosrotehrani is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Evaluating the impact of social determinants of health on skin cancer outcomes
Principal Advisor
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Master Philosophy
A Pilot Observational Study of Changes in Naevi during Pregnancy using Total-Body Photography
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Master Philosophy
Evaluating the impact of social determinants of health on melanoma outcomes
Principal Advisor
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Doctor Philosophy
Predicting melanoma survival using advanced digital imaging technologies
Principal Advisor
Other advisors: Dr Quan Nguyen
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Master Philosophy
Spatial omics to characterize the clinicopathologic subsets of melanoma
Principal Advisor
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Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
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Doctor Philosophy
Understanding and targeting determinants of mortality from melanoma
Principal Advisor
Other advisors: Dr Lena Von Schuckmann
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Doctor Philosophy
Mechanisms of Vascular Remodelling in Melanoma
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Master Philosophy
Understanding the mechanisms for increased mortality risk for pregnancy-associated melanoma.
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass, Dr Abbas Shafiee, Associate Professor Jason Lee
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Doctor Philosophy
Characterizing the role of ion channel kinase in skin homeostasis
Associate Advisor
Other advisors: Professor Fiona Simpson, Dr Snehlata Kumari
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Master Philosophy
Antibody-mediated exacerbation of Pseudomonas aeruginosa infected chronic wounds
Associate Advisor
Other advisors: Associate Professor Timothy Wells
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Doctor Philosophy
Understanding immune diversity in skin inflammation
Associate Advisor
Other advisors: Professor Gabrielle Belz, Dr Snehlata Kumari
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Doctor Philosophy
Understanding Melanoma Vascularisation to prevent metastasis
Associate Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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Master Philosophy
Evaluating the effects of chronic diseases and lifestyle on the risk of melanoma recurrence
Associate Advisor
Other advisors: Dr Lena Von Schuckmann
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Master Philosophy
Antibody mediated exacerbation of Pseudomonas aeruginosa infected chronic wounds
Associate Advisor
Other advisors: Associate Professor Timothy Wells
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Doctor Philosophy
Predictive and prognostic biomarkers for melanoma progression (BioMEL)
Associate Advisor
Other advisors: Associate Professor Mitchell Stark
Completed supervision
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2024
Doctor Philosophy
Mechanisms of Vascular Remodelling in Melanoma
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2024
Master Philosophy
Anatomical Distribution and Immunoprevention of Keratinocyte Carcinoma
Principal Advisor
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2024
Doctor Philosophy
Identifying genetic and epigenetic regulators of skin and hair follicle physiology and disease in mice: A systems-based approach using The Collaborative Cross
Principal Advisor
Other advisors: Dr Sally Mortlock
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2024
Doctor Philosophy
Potency and activity of meso-endothelial bipotent progenitors in vivo in homeostasis and injury
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Doctor Philosophy
Deciphering the Influence of Macrophages on Endothelial Progenitors
Principal Advisor
Other advisors: Professor Allison Pettit, Dr Simranpreet Kaur, Professor Antje Blumenthal
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2023
Doctor Philosophy
Investigating the contribution of vascular Sox9 to fibrosis in homeostasis and systemic sclerosis
Principal Advisor
Other advisors: Dr Simranpreet Kaur
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2023
Master Philosophy
Mutation burden as a biomarker of keratinocyte cancer risk prediction and field treatment efficacy
Principal Advisor
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2022
Doctor Philosophy
Defining endovascular progenitors in homeostasis and disease
Principal Advisor
Other advisors: Ms Laura Sormani Le Bourhis
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2022
Doctor Philosophy
Uncovering the Role of Endovascular Progenitors in Melanoma Development and Metastatic Progression
Principal Advisor
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2020
Master Philosophy
Predicting melanoma outcome using clinical and biological indicators
Principal Advisor
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2019
Master Philosophy
Dissecting Molecular Events in Pregnancy-Associated Melanoma
Principal Advisor
Other advisors: Associate Professor Helmut Schaider
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2018
Master Philosophy
Understanding the differences between basal cell carcinoma subtypes at the genomic and transcriptomic level.
Principal Advisor
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2018
Doctor Philosophy
The Role of Skin Macrophages Under Conditions of Stress and Injury: Ultraviolet Irradiation and Wound Healing
Principal Advisor
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2017
Doctor Philosophy
Prognostic factors in early stage invasive cutaneous melanoma
Principal Advisor
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2017
Doctor Philosophy
A Genome-wide Approach to Identify Genetic Determinants of Skin Wound Healing and Scar Formation.
Principal Advisor
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2015
Master Philosophy
The influence of pregnancy, parity, and sex on melanoma prognosis
Principal Advisor
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2015
Doctor Philosophy
Mesenchymal-Epidermal Interactions in Hair Follicle Cycling and Regeneration
Principal Advisor
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2020
Doctor Philosophy
Natural history of high-risk cutaneous primary melanoma and risk factors for disease progression
Associate Advisor
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2018
Doctor Philosophy
The role of SOX7 transcription factor in early blood vessel development
Associate Advisor
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2014
Doctor Philosophy
Immune mediators of alloreactive responses in allogeneic stem cell transplantation and in pregnancy-induced microchimerism
Associate Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2013
Doctor Philosophy
Endogenous stem cell behaviour in tissue repair: lessons from fetal microchimerism
Associate Advisor
Media
Enquiries
Contact Professor Kiarash Khosrotehrani directly for media enquiries about:
- basal cell carcinoma
- Dermatology
- Fetal stem cells
- Melanoma
- Skin cancer
- Skin wound healing
- squamous cell carcinoma
- Stem cells - fetal
- Stem cells - skin wound healing
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