Emeritus Professor Istvan Toth
Emeritus Professor

Istvan Toth

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Background

Professor István Tóth is Chair in Biological Chemistry at The University of Queensland (UQ), Brisbane, Australia, and Affiliated Professorial Research Fellow at the Institute of Molecular Biosciences, UQ. He graduated with a degree in Chemical Engineering from the Technical University, Budapest, Hungary and was awarded his PhD for his Alkaloid Chemistry research. Professor Tóth undertook a postdoctoral fellowship at Carleton University, Ottawa Canada before returning to Hungary to work as a Research Associate, then Scientific Group Leader at the Central Research Institute for Chemistry, Hungarian Academy of Science. He joined the School of Pharmacy at the University of London in 1987 as a Senior Lecturer and Royal Society sponsored Senior Research Fellow. He became a Reader in Medicinal Organic Chemistry in 1994 and was awarded a Doctor of Science degree (DSc 1994) for his work in Drug Delivery (Hungarian Academy of Sciences), before relocating to the University of Queensland in 1998 where he has built a productive research group. Professor Tóth was a visiting professor at the School of Pharmacy, University of London (1994-2004) and at the Department of Bioengineering and Therapeutic Science, University of California, San Francisco (2011-2013). Professor Tóth’s major research interests are: drug delivery, immunoadjuvants, carbohydrates, lipids, peptides, nucleosides, and nucleotides. This research has attracted over $85 million in competitive grants, research contracts and investment funds in the past 10 years. Professor Tóth has over 500 peer-reviewed publications, 45 patents, and an excellent track record in research commercialisation. He is a one of key founders of Alchemia, Implicit Bioscience Pty Ltd, Neurotide Pty Ltd and TetraQ (the commercial arm of Centre of Integrated Preclinical Drug Development). Professor Tóth is an elected RACI Fellow and Fellow of the Queensland Academy of Arts and Sciences. and Feklloiw of the Hungarian Academy of Sciences (since 2016) In 2009 he was awarded the Adrian Albert award for sustained and outstanding research in medicinal biochemistry, and a Business/Higher Education Round Table (BHERT) Award for Outstanding Achievement in International Collaborative Research and Development he obtained the Doctor Honoris Causa degree at Semmelweis university budapest Hungary (2019). Professor Tóth was appointed as a member of the ARC College of Experts (2008-2010). He was the founding (2007) then the elected (2008-2009) President of the Australian Chapter of Controlled Release Society.

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision
Media expert

Fields of research

Medicinal and biomolecular chemistry Organic chemistry

Qualifications

  • Doctor of Philosophy of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics
  • Doctoral Diploma of Medicinal and Biomolecular Chemistry, Budapest University of Technology and Economics

Search Professor Istvan Toth’s works on UQ eSpace

683 works between 1972 and 2025
All (683) Journal Article (480) Book Chapter (42) Conference Publication (151) Book (3) Other Outputs (6) Edited Outputs (1)

401 - 420 of 683 works

2006

Conference Publication

The synthesis of a novel dendritic system for gene delivery

Coles, D. J., Yang, S, Esposito, A., Mitchell, D J, Minchin, R F and Toth, I (2006). The synthesis of a novel dendritic system for gene delivery. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

The synthesis of a novel dendritic system for gene delivery

2006

Conference Publication

The lipid core peptide system in vaccine delivery

Toth, I., Moyle, P. M., Karpati, L., Horvath, A., Olive, C. and Good, M. F. (2006). The lipid core peptide system in vaccine delivery. XVIth Lancefield International Symposium on Streptococci and Streptococcal Diseases, Palm Cove, Australia, 25 and 29 September 2005. Amsterdam, The Netherlands: Excerpta Medica Foundation. doi: 10.1016/j.ics.2005.11.057

The lipid core peptide system in vaccine delivery

2006

Conference Publication

The synthesis of a novel dendritic system for gene delivery

Coles, D. J., Yang, S., Esposito, A., Mitchell, D. J., Minchin, R. F. and Toth, I. (2006). The synthesis of a novel dendritic system for gene delivery. Annual Conference of the Australasian Pharmaceutical Science Association, Adelaide, Australia, 3-5 December, 2006.

The synthesis of a novel dendritic system for gene delivery

2006

Journal Article

Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A

White, Karen, Rades, Thomas, Kearns, Philip, Toth, Istvan and Hook, Sarah (2006). Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A. Pharmaceutical Research, 23 (7), 1473-1481. doi: 10.1007/s11095-006-0272-z

Immunogenicity of liposomes containing lipid core peptides and the adjuvant Quil A

2006

Journal Article

Protein transduction by lipidic peptide dendrimers

Bayele, Henry K., Ramaswamy, Chandrasekaran, Wilderspin, Andrew F., Srai, Kaila S., Toth, Istvan and Florence, Alexander T. (2006). Protein transduction by lipidic peptide dendrimers. Journal of Pharmaceutical Sciences, 95 (6), 1227-1237. doi: 10.1002/jps.20606

Protein transduction by lipidic peptide dendrimers

2006

Conference Publication

Synthetic lipopeptides formulated in liposomes: effect on their immune stimulatory capacity in vitro

Liang, Ming T., Hennessy, Tania, Toth, Istvan, Davies, Nigel M. and Hook, Sarah (2006). Synthetic lipopeptides formulated in liposomes: effect on their immune stimulatory capacity in vitro. International Conference on Nanoscience and Nanotechnology, Brisbane Australia, Jul 03-07, 2006. NEW YORK: IEEE.

Synthetic lipopeptides formulated in liposomes: effect on their immune stimulatory capacity in vitro

2006

Conference Publication

Caco-2 cell permeability and stability assays of two d-glycopyranuronanamide conjugates of thyrotropic releasing hormone

Wessling, S., Ross, B P, Blanchfield, J T and Toth, I (2006). Caco-2 cell permeability and stability assays of two d-glycopyranuronanamide conjugates of thyrotropic releasing hormone. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 Nov 2006.

Caco-2 cell permeability and stability assays of two d-glycopyranuronanamide conjugates of thyrotropic releasing hormone

2006

Conference Publication

Synthetic lipopeptides formulated in liposomes: Effect on their immune stimulatory capacity in vitro

Liang, M, Hennessy, T., Toth, I, Davies, N M and Hook, S. (2006). Synthetic lipopeptides formulated in liposomes: Effect on their immune stimulatory capacity in vitro. 2006 International Conference on Nanoscience and Nanotechnoloy, Brisbane / Brisbane Convention Centre, 3-7 July 2006. Canberra: IEEE.

Synthetic lipopeptides formulated in liposomes: Effect on their immune stimulatory capacity in vitro

2006

Journal Article

Dde as a protecting group for carbohydrate synthesis

Bornaghi, L., Dekany, G., Drinnan, N. B., Taylor, S., Toth, I. and West, M. L. (2006). Dde as a protecting group for carbohydrate synthesis. Journal of Carbohydrate Chemistry, 25 (1), 1-18. doi: 10.1080/07328300500388685

Dde as a protecting group for carbohydrate synthesis

2006

Journal Article

Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide

Everett, Ruth S., Vanhook, Miriam K., Barozzi, Nadia, Toth, Istvan and Johnson, Larry G. (2006). Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide. Molecular Pharmacology, 69 (2), 492-500. doi: 10.1124/mol.105.017251

Specific modulation of airway epithelial tight junctions by apical application of an occludin peptide

2006

Conference Publication

Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A streptococcus

Fujita, Y, Moyle, P. M., Olive, C., Good, M F and Toth, I (2006). Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A streptococcus. 29th European Peptide Symposium, Gdansk, 3-8 Sept, 2006.

Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A streptococcus

2006

Conference Publication

Modified influenza virosomes for gene delivery

Khoshnejad, M., Toth, I., Young, P. R. and Minchin, R. F. (2006). Modified influenza virosomes for gene delivery. Brisbane Biological & Organic Chemistry Symposium, Brisbane, Qld, 24 Nov 2006.

Modified influenza virosomes for gene delivery

2006

Conference Publication

Liposaccharides in peptide, gene and vaccine delivery

Toth, I., Moyle, P. M., Koda, Y., Olive, C. and Good, M. F. (2006). Liposaccharides in peptide, gene and vaccine delivery. 33rd Annual Meeting and Exposition of the Controlled Release Soy, Vienna, 22-26 July, 2006.

Liposaccharides in peptide, gene and vaccine delivery

2006

Journal Article

Particulate systems as adjuvants and carriers for peptide and protein antigens

Liang, M T, Davies, N M, Blanchfield, J T and Toth, I (2006). Particulate systems as adjuvants and carriers for peptide and protein antigens. Current Drug Delivery, 3 (4), 379-388. doi: 10.2174/156720106778559029

Particulate systems as adjuvants and carriers for peptide and protein antigens

2006

Conference Publication

Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A Streptococcus

Fujita, Y., Moyle, P., Olive, C., Good, M. and Toth, I. (2006). Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A Streptococcus. CHICHESTER: JOHN WILEY & SONS LTD.

Multi-epitopic lipid core peptide vaccine with broad protective immune responses against Group A Streptococcus

2006

Conference Publication

Liposaccharides in peptide, gene and vaccine delivery

Toth, I., Moyle, P. M., Simerska, P., Fujita, Y., Olive, C. and Good, M. F. (2006). Liposaccharides in peptide, gene and vaccine delivery. Drug Design Amongst the Vines, Hunter Valley, 3 - 7 December, 2006.

Liposaccharides in peptide, gene and vaccine delivery

2006

Conference Publication

Enhancement of drug oral absorption - effect of lipidic conjugation on the stability and permeability of a dipeptide amide derivative in Caco-2 models

Bergeon, J and Toth, I (2006). Enhancement of drug oral absorption - effect of lipidic conjugation on the stability and permeability of a dipeptide amide derivative in Caco-2 models. Brisbane Biological & Organic Chemistry Symposium, Brisbane, 24 November 2006.

Enhancement of drug oral absorption - effect of lipidic conjugation on the stability and permeability of a dipeptide amide derivative in Caco-2 models

2006

Journal Article

Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine

Moyle, P. M., Olive, C., Ho, M.-F., Burgess, M., Karpati, L., Good, M. F. and Toth, I. (2006). Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine. International Congress Series, 1289, 324-328. doi: 10.1016/j.ics.2005.11.084

Towards the synthesis of a highly pure, multiepitopic, mucosal group A streptoccal lipopeptide vaccine

2006

Journal Article

Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide

Caccetta, R., Blanchfield, J. T., Harrison, J., Toth, I. and Benson, H. A. E. (2006). Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide. International Journal of Peptide Research and Therapeutics, 12 (3), 327-333. doi: 10.1007/s10989-006-9024-5

Epidermal penetration of a therapeutic peptide by lipid conjugation; Stereo-selective peptide availability of a topical diastereomeric lipopeptide

2006

Conference Publication

Liposaccharides in peptide, gene and vaccine delivery

Toth, I, Moyle, P. M., Koda, Y., Olive, C. and Good, M F (2006). Liposaccharides in peptide, gene and vaccine delivery. 10th Naples Workshop on Bioactive Peptides, Naples, 11-14 June, 2006.

Liposaccharides in peptide, gene and vaccine delivery

Current funding

  • 2024 - 2025
    Single-shot anti-fertility vaccine in pigs
    Australia's Economic Accelerator Seed Grants
    Open grant

Availability

Emeritus Professor Istvan Toth is:
Not available for supervision

Supervision history

Current supervision

Completed supervision

Enquiries

Contact Emeritus Professor Istvan Toth directly for media enquiries about:

  • Chemistry - lipid
  • Chemistry - medicinal
  • Chemistry - peptide
  • Chemistry - sugar
  • Drug - oral administration
  • Drug delivery
  • Genes and vaccines
  • Immunisation
  • Lipid chemistry
  • Medicinal chemistry
  • Oral administration of vaccines
  • Peptide chemistry
  • Peptide drug delivery
  • Sugar chemistry
  • Vaccines - oral administration
  • Vaccines and genes

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