
Overview
Background
After completing my undergraduate and postgraduate studies at the University of Newcastle, I held a Postdoctoral Fellowship at the University of Basel (Switzerland) from 1990-2. I returned to Australia in 1993 to take up an Australian Research Council Postdoctoral Fellowship at the Australian National University (Canberra) from 1993-4. I joined The University of Queensland in 1994.
Availability
- Professor Paul Bernhardt is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy, University of Newcastle
Research interests
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Protein Electrochemistry
This research involves incorporating redox active enzymes with electrochemical systems such that the enzyme functions natively whilst in communication with an electrode (rather than with a natural electron transfer partner). We are currently investigating a number of systems, most from the molybdenum enzyme family that catalyse oxygen transfer reactions of both organic and inorganic substrates.
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Copper Complexes as Atom Transfer Radical Catalysts
Atom transfer radical polymerisation (ATRP) is one of the most widely used 'controlled' radical polymerisation techniques and has resulted in polymers with well defined molecular weights and architectures. Our work is focused on complexes that catalyse this process by generating organic radicals from the simple reaction between a Cu(I) complex and an alkyl halide initiator. We can probe this atom transfer reaction with cyclic voltammetry and we have gained new insight to this interesting and fundamentally important reaction. This has now progressed to developing electrocatalytic synthetic methods for C-C bond formation reactions in collaboration with Prof. Craig Williams (SCMB).
Research impacts
My research interests include all aspects of coordination chemistry; particularly its relevance to the areas of electrochemistry, bioinorganic chemistry, spectroscopy and catalysis.
In recent years some of the areas in which we have been, and continue to be, actively involved include:
- Enzyme electrochemistry (collaborations with several UQ and international groups).
- Invesitigation of copper complexes that are active in atom transfer radical polymerisation catalysis
- Transition metal-mediated organic oxidation and reduction reactions
Works
Search Professor Paul Bernhardt’s works on UQ eSpace
1997
Journal Article
Macrocycle formation through carbon acid-formaldehyde condensation reactions of bis(propane-1,2-diamine)- and bis (2-methylpropane-1,2-diamine)-copper(II) ions
Rossignoli, M, Bernhardt, PV, Lawrance, GA and Maeder, M (1997). Macrocycle formation through carbon acid-formaldehyde condensation reactions of bis(propane-1,2-diamine)- and bis (2-methylpropane-1,2-diamine)-copper(II) ions. Australian Journal of Chemistry, 50 (6), 529-534. doi: 10.1071/C96219
1996
Journal Article
The potentially hexadentate isomeric macrocycles trans- and cis-6,13-diethyl-1,4,8,11-tetraazacyclotetradecane-6,13-diamine and their cobalt(III) complexes: Unexpected conformational behavior
Bernhardt, P.V., Byriel, K.A., Kennard, C.H.L. and Sharpe, P.C. (1996). The potentially hexadentate isomeric macrocycles trans- and cis-6,13-diethyl-1,4,8,11-tetraazacyclotetradecane-6,13-diamine and their cobalt(III) complexes: Unexpected conformational behavior. Inorganic Chemistry, 35 (7), 2045-2052. doi: 10.1021/ic951260y
1996
Journal Article
Stereoselective assembly of a new pendant-arm macrocycle
Bernhardt, Paul V., Byriel, Karl A., Kennard, Colin H. L. and Sharpe, Philip C. (1996). Stereoselective assembly of a new pendant-arm macrocycle. Journal of the Chemical Society - Dalton Transactions (1), 145-146. doi: 10.1039/dt9960000145
1996
Journal Article
Unexpected rearrangement of a novel pendent-arm tetraazamacrocyclic complex
Bernhardt P.V. and Sharpe P.C. (1996). Unexpected rearrangement of a novel pendent-arm tetraazamacrocyclic complex. Chemical Communications (11), 1267-1268. doi: 10.1039/cc9960001267
1996
Journal Article
N-methylation of diamino-substituted macrocyclic complexes: Intermolecular reactions
Bernhardt, PV (1996). N-methylation of diamino-substituted macrocyclic complexes: Intermolecular reactions. Journal of The Chemical Society-dalton Transactions (23), 4319-4324. doi: 10.1039/dt9960004319
1996
Journal Article
N-methylation of diamino-substituted macrocyclic complexes: Intramolecular cyclisation
Bernhardt, PV, Hetherington, JC and Jones, LA (1996). N-methylation of diamino-substituted macrocyclic complexes: Intramolecular cyclisation. Journal of The Chemical Society-dalton Transactions (23), 4325-4330. doi: 10.1039/dt9960004325
1995
Journal Article
COPPER(II) COMPLEXES OF SUBSTITUTED MACROBICYCLIC HEXAAMINES - COMBINED TRIGONAL AND TETRAGONAL DISTORTIONS
BERNHARDT, PV, BRAMLEY, R, ENGELHARDT, LM, HARROWFIELD, JM, HOCKLESS, DCR, KORYBUTDASZKIEWICZ, BR, KRAUSZ, ER, MORGAN, T, SARGESON, AM, SKELTON, BW and WHITE, AH (1995). COPPER(II) COMPLEXES OF SUBSTITUTED MACROBICYCLIC HEXAAMINES - COMBINED TRIGONAL AND TETRAGONAL DISTORTIONS. Inorganic Chemistry, 34 (14), 3589-3599. doi: 10.1021/ic00118a005
1994
Journal Article
N-METHYLATED MACROBICYCLIC HEXAAMINES OF COPPER(II) AND NICKEL(II) - LARGE STERIC EFFECTS
BERNHARDT, PV, HARROWFIELD, JM, HOCKLESS, DCR and SARGESON, AM (1994). N-METHYLATED MACROBICYCLIC HEXAAMINES OF COPPER(II) AND NICKEL(II) - LARGE STERIC EFFECTS. Inorganic Chemistry, 33 (25), 5659-5670. doi: 10.1021/ic00103a011
1994
Journal Article
STABILIZATION OF COBALT CAGE CONFORMERS IN THE SOLID-STATE AND SOLUTION
BERNHARDT, PV, BYGOTT, AMT, GEUE, RJ, HENDRY, AJ, KORYBUTDASZKIEWICZ, BR, LAY, PA, PLADZIEWICZ, , SARGESON, AM and WILLIS, AC (1994). STABILIZATION OF COBALT CAGE CONFORMERS IN THE SOLID-STATE AND SOLUTION. Inorganic Chemistry, 33 (20), 4553-4561. doi: 10.1021/ic00098a023
1994
Journal Article
QUINQUEDENTATE COORDINATION OF 3-[(2'-AMINO-ETHYL)AMINO]-2-[(2''-AMINOETHYL)AMINOMETHYL]PROPIONIC ACID (LH) - CRYSTAL-STRUCTURE OF TRANS-[CO(L)CL][CLO4].H2O AND MOLECULAR MECHANICS EXAMINATION OF ISOMERS
BERNHARDT, PV, HAMBLEY, TW, LAWRANCE, GA and MOLLOY, KJ (1994). QUINQUEDENTATE COORDINATION OF 3-[(2'-AMINO-ETHYL)AMINO]-2-[(2''-AMINOETHYL)AMINOMETHYL]PROPIONIC ACID (LH) - CRYSTAL-STRUCTURE OF TRANS-[CO(L)CL][CLO4].H2O AND MOLECULAR MECHANICS EXAMINATION OF ISOMERS. Australian Journal of Chemistry, 47 (5), 817-827. doi: 10.1071/CH9940817
1994
Journal Article
METAL-DIRECTED SYNTHESIS OF MACROCYCLIC TETRAAMINES WITH PENDANT NITRO OR AMINE GROUPS, BASED ON TRANS-CYCLOHEXANE-1,2-DIAMINE
BERNHARDT, PV, COMBA, P, ELLIOTT, BL, LAWRANCE, GA, MAEDER, M, OLEARY, MA, WEI, G and WILKES, EN (1994). METAL-DIRECTED SYNTHESIS OF MACROCYCLIC TETRAAMINES WITH PENDANT NITRO OR AMINE GROUPS, BASED ON TRANS-CYCLOHEXANE-1,2-DIAMINE. Australian Journal of Chemistry, 47 (6), 1171-1178. doi: 10.1071/CH9941171
1993
Journal Article
RESOLUTION OF RACEMIC AMINO-ACIDS VIA STEREOSELECTIVE LIGAND-EXCHANGE REACTIONS ON AN OPTICALLY PURE NICKEL(II) COMPLEX
BERNHARDT, PV, COMBA, P, HAMBLEY, TW, SOVAGO, and VARNAGY, K (1993). RESOLUTION OF RACEMIC AMINO-ACIDS VIA STEREOSELECTIVE LIGAND-EXCHANGE REACTIONS ON AN OPTICALLY PURE NICKEL(II) COMPLEX. Journal of the Chemical Society-Dalton Transactions (13), 2023-2026. doi: 10.1039/dt9930002023
1993
Journal Article
PREDICTION AND INTERPRETATION OF ELECTRONIC-SPECTRA OF TRANSITION-METAL COMPLEXES VIA THE COMBINATION OF MOLECULAR MECHANICS AND ANGULAR OVERLAP MODEL-CALCULATIONS
BERNHARDT, PV and COMBA, P (1993). PREDICTION AND INTERPRETATION OF ELECTRONIC-SPECTRA OF TRANSITION-METAL COMPLEXES VIA THE COMBINATION OF MOLECULAR MECHANICS AND ANGULAR OVERLAP MODEL-CALCULATIONS. Inorganic Chemistry, 32 (13), 2798-2803. doi: 10.1021/ic00065a003
1993
Journal Article
COMPLEXATION OF CIS-6,13-DIMETHYL-1,4,8,11-TETRAAZACYCLOTETRADECANE-6,13-DIAMINE WITH THE 1ST ROW TRANSITION-METAL IONS COBALT(III), CHROMIUM(III), AND NICKEL(II)
BERNHARDT, PV, COMBA, P and HAMBLEY, TW (1993). COMPLEXATION OF CIS-6,13-DIMETHYL-1,4,8,11-TETRAAZACYCLOTETRADECANE-6,13-DIAMINE WITH THE 1ST ROW TRANSITION-METAL IONS COBALT(III), CHROMIUM(III), AND NICKEL(II). Inorganic Chemistry, 32 (13), 2804-2809. doi: 10.1021/ic00065a004
1993
Journal Article
CHIRAL QUADRIDENTATE LIGANDS BASED ON AMINO-ACIDS - TEMPLATE SYNTHESES AND PROPERTIES OF THE FREE LIGANDS AND THEIR TRANSITION-METAL COMPLEXES
BALLA, J, BERNHARDT, PV, BUGLYO, P, COMBA, P, HAMBLEY, TW, SCHMIDLIN, R, STEBLER, S and VARNAGY, K (1993). CHIRAL QUADRIDENTATE LIGANDS BASED ON AMINO-ACIDS - TEMPLATE SYNTHESES AND PROPERTIES OF THE FREE LIGANDS AND THEIR TRANSITION-METAL COMPLEXES. Journal of the Chemical Society-Dalton Transactions (7), 1143-1149. doi: 10.1039/dt9930001143
1993
Journal Article
FORMATION OF EXOCYCLIC OLEFINIC GROUPS VIA STEREOSELECTIVE NITROSATIONS - A NEW ROUTE TOWARDS PENDANT ARM MACROCYCLIC LIGANDS
BERNHARDT, PV and COMBA, P (1993). FORMATION OF EXOCYCLIC OLEFINIC GROUPS VIA STEREOSELECTIVE NITROSATIONS - A NEW ROUTE TOWARDS PENDANT ARM MACROCYCLIC LIGANDS. Journal of the Chemical Society-Chemical Communications (2), 113-114. doi: 10.1039/c39930000113
1992
Journal Article
TRANSITION-METAL COMPLEXES OF THE NOVEL TRIDENTATE DI-2-PYRIDYLMETHANAMINE (DIPA)
BERNHARDT, PV, COMBA, P, MAHURICKENBACH, A, STEBLER, S, STEINER, S, VARNAGY, K and ZEHNDER, M (1992). TRANSITION-METAL COMPLEXES OF THE NOVEL TRIDENTATE DI-2-PYRIDYLMETHANAMINE (DIPA). Inorganic Chemistry, 31 (20), 4194-4200. doi: 10.1021/ic00046a038
1992
Journal Article
MOLECULAR MECHANICS CALCULATIONS OF TRANSITION-METAL COMPLEXES
BERNHARDT, PV and COMBA, P (1992). MOLECULAR MECHANICS CALCULATIONS OF TRANSITION-METAL COMPLEXES. Inorganic Chemistry, 31 (12), 2638-2644. doi: 10.1021/ic00038a060
1992
Journal Article
DETERMINATION OF SOLUTION STRUCTURES OF BINUCLEAR COPPER(II) COMPLEXES
BERNHARDT, PV, COMBA, P, HAMBLEY, TW, MASSOUD, SS and STEBLER, S (1992). DETERMINATION OF SOLUTION STRUCTURES OF BINUCLEAR COPPER(II) COMPLEXES. Inorganic Chemistry, 31 (12), 2644-2651. doi: 10.1021/ic00038a061
1992
Journal Article
PREDICTIONS AND METHODS OF SEPARATION OF RACEMIC BIDENTATE LIGANDS VIA STEREOSELECTIVE LIGAND-EXCHANGE REACTIONS
BERNHARDT, PV, COMBA, P, GYR, T and VARNAGY, K (1992). PREDICTIONS AND METHODS OF SEPARATION OF RACEMIC BIDENTATE LIGANDS VIA STEREOSELECTIVE LIGAND-EXCHANGE REACTIONS. Inorganic Chemistry, 31 (7), 1220-1223. doi: 10.1021/ic00033a018
Funding
Current funding
Past funding
Supervision
Availability
- Professor Paul Bernhardt is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Developing novel copper catalysts for carbon-carbon bond forming reactions using electrosynthesis.
Principal Advisor
Other advisors: Professor Craig Williams, Dr Masnun Naher
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Doctor Philosophy
Quantum Chemistry as a tool for Spectroscopic Analysis
Principal Advisor
-
Doctor Philosophy
Quantum Chemistry as a tool for Spectroscopic Analysis
Principal Advisor
-
Doctor Philosophy
New Applications for Photoactive Lanthanoid and Earth Abundant Metal Complexes
Associate Advisor
Other advisors: Associate Professor Evan Moore
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Doctor Philosophy
Pioneering stable copper carbanions for new C-C bond forming paradigms
Associate Advisor
Other advisors: Professor Craig Williams
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Doctor Philosophy
Electrochemical investigations of bacterial molybdenum enzymes
Associate Advisor
Other advisors: Professor Ulrike Kappler
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Doctor Philosophy
Development of innovative synthetic methodologies: electrochemical Atom Transfer Radical Addition (eATRA) and strained nitrogen ring synthesis paradigms
Associate Advisor
Other advisors: Professor Craig Williams
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Doctor Philosophy
New Applications for Photoactive Lanthanoid and Earth Abundant Metal Complexes
Associate Advisor
Other advisors: Associate Professor Evan Moore
Completed supervision
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2024
Doctor Philosophy
Immobilisation of human molybdenum enzymes for mediated electrochemical catalysis
Principal Advisor
Other advisors: Professor Gary Schenk
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2023
Doctor Philosophy
Electrocatalysis at the Atypical Cu(II)-C bond: Electrochemical and Spectroscopic Studies
Principal Advisor
Other advisors: Professor Craig Williams
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2017
Doctor Philosophy
Understanding the Mechanisms of Transition Metal Catalysed Redox Reactions
Principal Advisor
Other advisors: Professor Michael Monteiro
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2011
Doctor Philosophy
Tuning the redox potential of conducting polymeric films
Principal Advisor
Other advisors: Dr Philip Sharpe
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2010
Doctor Philosophy
The molecular basis for sulfite oxidation in a bacterial sulfite dehydrogenase from Starkeya novella
Principal Advisor
Other advisors: Professor Ulrike Kappler
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2009
Doctor Philosophy
Mediated Electrochemistry of DMSO Reductase from Rhodobacter capsulatus
Principal Advisor
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2009
Doctor Philosophy
Iron chelators in the treatment of cancer
Principal Advisor
Other advisors: Dr Philip Sharpe
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2008
Doctor Philosophy
Structural and mechanistic investigations into Dimethylsulfide dehyddrogenase from Rhodovulum sulfidophilum; a moyybdoenzyme from the DMSO reductase family
Principal Advisor
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2004
Doctor Philosophy
DISCRETE CYANO-BRIDGED MIXED VALENCE SYSTEMS
Principal Advisor
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2004
Doctor Philosophy
ORALLY ACTIVE CHELATORS FOR THE TREATMENT OF IRON OVERLOAD DISEASES
Principal Advisor
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2004
Doctor Philosophy
A MACROCYCLIC SCAFFOLD FOR ELECTRONIC ENERGY TRANSFER AND PHOTOINDUCED ELECTRON TRANSFER
Principal Advisor
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2002
Doctor Philosophy
INORGANIC COMPLEXES AS CANDIDATES FOR ENERGY UPCONVERSION MATERIALS
Principal Advisor
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2002
Doctor Philosophy
MACROCYCLIC COMPLEXES AS CHEMICAL RECEPTORS
Principal Advisor
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2023
Doctor Philosophy
Characterisation of Bacterial Cytochromes P450
Associate Advisor
Other advisors: Professor James De Voss
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2017
Doctor Philosophy
Modifications and a Mechanistic Study of the Ley-Griffith Oxidation, and Generation of Hydroxyl Radicals in the Gas Phase
Associate Advisor
Other advisors: Professor Craig Williams
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2008
Doctor Philosophy
Cytochrome P450cin: Chemistry and Biochemistry
Associate Advisor
Other advisors: Professor James De Voss
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2007
Doctor Philosophy
REDOX PROPERTIES AND MEMBRANE LOCALIZATION OF HUMAN RECOMBINANT CYTOCHROME P450 SYSTEMS
Associate Advisor
Other advisors: Professor Elizabeth Gillam, Professor James De Voss
Media
Enquiries
Contact Professor Paul Bernhardt directly for media enquiries about:
- Crystallography
- Electrochemistry
- Transition metal chemistry
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