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Emeritus Professor Maree Smith
Emeritus Professor

Maree Smith

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Overview

Background

Update Profile

Emeritus Professor Maree Smith AC FTSE FAHMS is a full-time researcher and Director, CIPDD, School of Biomedical Sciences, Faculty of Medicine, The University of Queensland.

In the 12 years prior to her current appointment, Professor Smith led a high-performing team in building the CIPDD and its commercial interface TetraQ, recognized as a unique, GLP-accredited drug development Centre in Australia. Professor Smith has considerable expertise in biomedical discovery/translation with specialist expertise in the novel pain therapeutics discovery/translation field encompassing a portfolio of 16 rodent pain models that mimic individual human pain conditions. This portfolio of models conducted in a purpose-built facility operated in accordance with the requirements of our Quality Management System, making the CIPDD unique in Australia and rare internationally.

In the 15 years prior to establishing the CIPDD, Professor Maree Smith was a full-time academic in the School of Pharmacy. In brief, she joined the School of Pharmacy as a Lecturer in 1989 and was successively promoted through the academic ranks to Professor in 2004. Prior to that she undertook a PhD and early postdoctoral training in clinical pharmacology with specialist expertise in bioanalytical method development, bioanalysis of human plasma samples, drug metabolism and clinical pharmacokinetics. Her second postdoc was in the field of pain management and pain pharmacology.

In the years, 1990-2005, Maree Smith taught in the Drug Discovery stream of the 2nd, 3rd & 4th years of the undergraduate Pharmacy program and she was instrumental in developing innovative courses for the final year of the undergraduate Pharmacy curriculum. She was also instrumental in the development of a course for the M Biotech program at UQ entitled “Quality Systems in Biotechnology” which continues to this day and is a compulsory course in the Program. Maree has successfully advised/co-advised to completion 33 PhD students, 2 Research Masters students and ~50 Honours students. She also served for 14 years as an external evaluator for the TGA.

Maree's Current Research Interests are as follows:

1. Subtle differences in the pathobiology of individual chronic pain conditions

2. Improving preclinical to clinical translation in novel analgesics development

3. Preclinical drug development of novel pain therapeutics

4. Preclinical drug development

Awards

2021 UQ Fellowship

2019 Companion of the Order of Australia (AC) in the Queen's Birthday Honours List

2018 Honorary Bragg Membership (The Royal Institution of Australia)

2016 Bowl of Hygeia Award (Pharmaceutical Society of Australia)

2016 Clunies Ross Knowledge Commercialisation Award (ATSE)

2015 Honoured to be included in inaugural list of Australia's top Innovators; viz Knowledge Nation 100

2015 Inaugural Inductee into the Life Sciences Queensland (LSQ) Hall of Fame

2015 Johnson and Johnson Innovaton AusBiotech Industry Excellen Award - Outstanding Leader category.

2015 Elected Fellow, Australian Academy of Health and Medical Sciences (AAHMS)

2015 Australian Pain Society Distinguished Member Award - For services to the promotion, treatment and science of pain management and lifelong contribution to the Australian Pain Society

2013 UQ Top 5 Inventor - Award by Thomson Reuters and UQ at inaugural Awards

2013 UQ Top 5 Innovator - Award by UniQuest Pty Ltd and UQ at inaugural Awards

2012 Queensland Life Sciences Industry Excellence Award jointly with Dr Jim Aylward

2011 Elected Fellow, Australian Academy of Technological Sciences (ATSE)

2009 Honorary Fellowship, Faculty of Pain Medicine, ANZCA (Australian and New Zealand College of Anaesthetists).

2008 WiT (Women in Technology): Biotech Outstanding Achievement Award

2002 Meritorious Mention for Sustained Excellence in Research Higher Degree Supervision

2001 Meritorious Mention for Sustained Excellence in Research Higher Degree Supervision

Availability

Emeritus Professor Maree Smith is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Research impacts

Maree is a leading researcher internationally in the pain field. Spinifex Pharmaceuticals was formed in 2005 to commercialize her angiotensin II type 2 (AT2) receptor antagonists technology for neuropathic pain and subsequently chronic inflammatory pain. Spinifex was acquired by Novartis in mid-2015 on the basis of successful early phase clinical trials in patients with post-herpetic neuralgia, a type of peripheral neuropathic pain that is often intractable.

Also, she has highly specialized expertise in the pain field encompassing a portfolio of 15 innovative rodent pain models that closely mimic individual human pain conditions. These models combined with the OECD GLP accreditation of the CIPDD facility means that these capabilities are unique in Australia and rare outside of large pharmaceutical companies internationally.

Works

Search Professor Maree Smith’s works on UQ eSpace

335 works between 1979 and 2024

61 - 80 of 335 works

2017

Journal Article

Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods

Muralidharan, Arjun, Park, Thomas S. W., Mackie, John T., Gimenez, Luiz G. S., Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2017). Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods. Frontiers in Pharmacology, 8 493, 493.1-493.12. doi: 10.3389/fphar.2017.00493

Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods

2016

Journal Article

High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation

Moosavi, Seyed Mojtaba, Shekar, Kiran, Fraser, John, Smith, Maree T. and Ghassabian, Sussan (2016). High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation. Journal of Chromatography B, 1038, 80-87. doi: 10.1016/j.jchromb.2016.10.038

High-throughput assay for quantification of the plasma concentrations of thiopental using automated solid phase extraction (SPE) directly coupled to LC–MS/MS instrumentation

2016

Journal Article

The Walker 256 breast cancer cell-induced bone pain model in rats

Shenoy, Priyank A., Kuo, Andy, Vetter, Irina and Smith, Maree T. (2016). The Walker 256 breast cancer cell-induced bone pain model in rats. Frontiers in Pharmacology, 7 (AUG) 286, 286. doi: 10.3389/fphar.2016.00286

The Walker 256 breast cancer cell-induced bone pain model in rats

2016

Journal Article

Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading

Han, Felicity Y., Thurecht, Kristofer J., Whittaker, Andrew K. and Smith, Maree T. (2016). Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading. Frontiers in Pharmacology, 7 (JUN) 185, 1-11. doi: 10.3389/fphar.2016.00185

Bioerodable PLGA-based microparticles for producing sustained-release drug formulations and strategies for improving drug loading

2016

Journal Article

Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain

Muralidharan, Arjun, Kuo, Andy, Jacob, Meera, Lourdesamy, Jacintha S., Melo Sores Pinho De Carvalho, Lara, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2016). Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain. Frontiers in Behavioral Neuroscience, 10 (88) 88, 88. doi: 10.3389/fnbeh.2016.00088

Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain

2016

Conference Publication

In vivo biodistribution of the nitric oxide donor, PRG150, using PET imaging in rats

Pippin, Adam, Voll, Ronald, Liotta, Dennis, Smith, Maree and Goodman, Mark (2016). In vivo biodistribution of the nitric oxide donor, PRG150, using PET imaging in rats. RESTON: SOC NUCLEAR MEDICINE INC.

In vivo biodistribution of the nitric oxide donor, PRG150, using PET imaging in rats

2016

Journal Article

In Vitro Metabolic Stability and in Vivo Biodistribution of 3‑Methyl-4- furoxancarbaldehyde Using PET Imaging in Rats

Pippin, Adam B., Mohd Arshad, Zaira Hidayah, Vol, Ronald J., Nye, Jonathon A., Ghassabian, Sussan, Williams, Craig M., Mancini, Alessandra, Liotta, Dennis C., Smith, Maree T. and Goodman, Mark M. (2016). In Vitro Metabolic Stability and in Vivo Biodistribution of 3‑Methyl-4- furoxancarbaldehyde Using PET Imaging in Rats. ACS Medicinal Chemistry Letters, 7 (6), 563-567. doi: 10.1021/acsmedchemlett.5b00410

In Vitro Metabolic Stability and in Vivo Biodistribution of 3‑Methyl-4- furoxancarbaldehyde Using PET Imaging in Rats

2016

Journal Article

Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere. Angewandte Chemie International Edition, 55 (11), 8359-8359. doi: 10.1002/anie.201681161

Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

2016

Journal Article

Evaluation of a high-throughput peptide reactivity format assay for assessment of the skin sensitization potential of chemicals

Wong, Chin Lin, Lam, Ai Leen, Smith, Maree T. and Ghassabian, Sussan (2016). Evaluation of a high-throughput peptide reactivity format assay for assessment of the skin sensitization potential of chemicals. Frontiers in Pharmacology, 7 (MAR) 53, 53. doi: 10.3389/fphar.2016.00053

Evaluation of a high-throughput peptide reactivity format assay for assessment of the skin sensitization potential of chemicals

2016

Journal Article

Validating Eaton's hypothesis: cubane as a benzene bioisostere

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Validating Eaton's hypothesis: cubane as a benzene bioisostere. Angewandte Chemie (International Edition), 55 (11), 3580-3585. doi: 10.1002/anie.201510675

Validating Eaton's hypothesis: cubane as a benzene bioisostere

2016

Journal Article

Selective small molecule angiotensin II type 2 (AT2) receptor antagonists for neuropathic pain: preclinical and clinical studies

Smith, Maree T., Anand, Praveen and Rice, Andrew S. C. (2016). Selective small molecule angiotensin II type 2 (AT2) receptor antagonists for neuropathic pain: preclinical and clinical studies. Pain, 157 (Supplement 1), S33-S41. doi: 10.1097/j.pain.0000000000000369

Selective small molecule angiotensin II type 2 (AT2) receptor antagonists for neuropathic pain: preclinical and clinical studies

2015

Journal Article

Why different pain-killers are only effective for certain types of pain

Smith, Maree (2015, 12 14). Why different pain-killers are only effective for certain types of pain

Why different pain-killers are only effective for certain types of pain

2015

Journal Article

A novel fully validated LC-MS/MS method for quantification of pyridoxal-5'-phosphate concentrations in samples of human whole blood

Ghassabian, Sussan, Griffiths, Lyn and Smith, Maree T (2015). A novel fully validated LC-MS/MS method for quantification of pyridoxal-5'-phosphate concentrations in samples of human whole blood. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 1000, 77-83. doi: 10.1016/j.jchromb.2015.07.019

A novel fully validated LC-MS/MS method for quantification of pyridoxal-5'-phosphate concentrations in samples of human whole blood

2015

Journal Article

Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture, TPM) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure

Smith, Maree T., Wyse, Bruce D., Edwards, Stephen R., El-Taminy, Mahmoud, Gaetano, Giacinto and Gavin, Paul (2015). Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture, TPM) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure. Journaal of Pharmaceutical Sciences, 104 (7), 2388-2396. doi: 10.1002/jps.24502

Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture, TPM) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure

2015

Journal Article

Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain

Han, Felicity Y., Thurecht, Kristofer J., Lam, Ai-Leen, Whittaker, Andrew K. and Smith, Maree T. (2015). Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain. Journal of Pharmaceutical Sciences, 104 (7), 2334-2344. doi: 10.1002/jps.24497

Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain

2015

Journal Article

The Furoxan Nitric Oxide Donor, PRG150, Evokes Dose-Dependent Analgesia in a Rat Model of Painful Diabetic Neuropathy (PDN)

Huang, Lillian Y., Tsui, Debbie Y., Williams, Craig M., Wyse, Bruce D. and Smith, Maree T. (2015). The Furoxan Nitric Oxide Donor, PRG150, Evokes Dose-Dependent Analgesia in a Rat Model of Painful Diabetic Neuropathy (PDN). Clinical and Experimental Pharmacology and Physiology, 42 (9), 921-929. doi: 10.1111/1440-1681.12442

The Furoxan Nitric Oxide Donor, PRG150, Evokes Dose-Dependent Analgesia in a Rat Model of Painful Diabetic Neuropathy (PDN)

2015

Journal Article

In vivo High Angular Resolution Diffusion-Weighted Imaging of Mouse Brain at 16.4 Tesla

Alomair, Othman I, Brereton, Ian M, Smith, Maree T, Galloway, Graham J and Kurniawan, Nyoman D (2015). In vivo High Angular Resolution Diffusion-Weighted Imaging of Mouse Brain at 16.4 Tesla. Plos One, 10 (6) e0130133, e0130133. doi: 10.1371/journal.pone.0130133

In vivo High Angular Resolution Diffusion-Weighted Imaging of Mouse Brain at 16.4 Tesla

2015

Journal Article

Neurotrophins and neuropathic pain: role in pathobiology

Khan, Nemat and Smith, Maree T. (2015). Neurotrophins and neuropathic pain: role in pathobiology. Molecules, 20 (6), 10657-10688. doi: 10.3390/molecules200610657

Neurotrophins and neuropathic pain: role in pathobiology

2015

Journal Article

Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cord

Khan, Nemat, Gordon, Richard, Woodruff, Trent M. and Smith, Maree T. (2015). Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cord. Pharmacology Research and Perspectives, 3 (3) e00137, 1-16. doi: 10.1002/prp2.137

Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cord

2015

Journal Article

In vitro methods for hazard assessment of industrial chemical - opportunities and challenges

Wong, Chin Lin, Ghassabian, Sussan, Smith, Maree T. and Lam, Ai-Leen (2015). In vitro methods for hazard assessment of industrial chemical - opportunities and challenges. Frontiers in Pharmacology, 6 (94) 94, 1-13. doi: 10.3389/fphar.2015.00094

In vitro methods for hazard assessment of industrial chemical - opportunities and challenges

Funding

Current funding

  • 2024 - 2025
    Novel ionophore combination therapeutic treatment (CARB-X grant administered by University of Melbourne)
    University of Melbourne
    Open grant
  • 2023 - 2028
    Centre for Integrated Preclinical Drug Development (CIPDD) NCRIS 2022 (administered by Therapeutic Innovation Australia (TIA))
    Therapeutic Innovation Australia Limited
    Open grant
  • 2023 - 2026
    Target validation of acid-sensing ion channel inhibitors to stop disease progression and manage pain in MS
    National Multiple Sclerosis Society-US
    Open grant
  • 2023 - 2025
    Breaking drug resistance in community acquired bacterial pneumonia (CABP) (NHMRC Development grant administered by University of Melbourne)
    University of Melbourne
    Open grant
  • 2022 - 2024
    Dose range finding and main efficacy study for one peptide-drug-conjugate using the MDA-MB-231 cell line-based xenograft mouse model of triple negative breast cancer
    University of Sydney
    Open grant
  • 2022 - 2024
    Assess the clinical disease-modifying effects of one peptide test item given twice-weekly for 3 weeks relative to sham control and vehicle in the relapsing-remitting experimental autoimmune encephalom
    Argenica Therapeutics Limited
    Open grant
  • 2022 - 2024
    Developing novel acid-sensing ion channel inhibitors as neuroprotective leads and diagnostic agents for multiple sclerosis
    Multiple Sclerosis Research Australia - Targeted Grant - Neurodegeneration
    Open grant
  • 2022 - 2026
    Mining the host-pathogen interface to deliver a drug pipeline for treating intractable and emerging infections
    NHMRC Synergy Grants
    Open grant
  • 2022 - 2024
    Novel long-acting and orally delivered conotoxin-based peptides with both analgesic efficacy and disease modifying potential
    NHMRC Development Grant
    Open grant

Past funding

  • 2020 - 2022
    Neuroprotective role of novel acid-sensing ion channel inhibitor in Multiple sclerosis (MS) disease
    Multiple Sclerosis Research Australia
    Open grant
  • 2019
    Advanced Brightfield and Fluorescent High Speed and Throughput Slide Scanner for biological, medical, materials science, and agricultural applications
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2021
    Development of a first-in-class neuroprotective drug for protecting the brain after stroke
    NHMRC Development Grant
    Open grant
  • 2019
    Vevo 3100 Imaging System for ultrahigh resolution and frame rate echocardiographic assessment of small animals.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    High-throughput ion channel pharmacology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2020
    Novel non-opioid analgesics
    NHMRC Development Grant
    Open grant
  • 2017 - 2018
    The impact of extracorporeal membrane oxygenation (ECMO) on the activities of drug enzymes that affect the pharmacokinetics and therapeutic outcomes of clinically important drugs
    Prince Charles Hospital Foundation
    Open grant
  • 2016
    Novel Pain therapeutics discovery: Probing molecular mechanisms
    NHMRC Equipment Grant
    Open grant
  • 2016 - 2019
    Novel prolonged-release polymeric microparticles for relief of intractable cancer-related pain
    NHMRC Project Grant
    Open grant
  • 2015 - 2016
    INK-004 Preliminary assessment of the analgesic efficacy of one test item following intrathecal bolus administration in a rat model of peripheral neuropathic pain
    UniQuest Pty Ltd
    Open grant
  • 2015 - 2022
    ACRF Facility for Molecular Imaging Agents in Cancer (AFMIAC)
    Australian Cancer Research Foundation
    Open grant
  • 2015
    Novel analgesics for improved relief of cancer induced bone pain
    UQ Collaboration and Industry Engagement Fund - Seed Research Grant
    Open grant
  • 2014 - 2015
    PHG-003 - Preparation of manuscript encompassing the data generated in studies PHG-001 and PHG-002 for publication in an international peer-reviewed journal
    UniQuest Pty Ltd
    Open grant
  • 2014 - 2023
    Translating Health Discovery (THD) - NCRIS 2013/2015/2016-17/2017-18/2018-19/2019-23 (administered by Therapeutic Innovation Australia (TIA))
    Therapeutic Innovation Australia Limited
    Open grant
  • 2014 - 2017
    Developing subtype-selective blockers of acid-sensing ion channels for treating peripheral pain
    NHMRC Project Grant
    Open grant
  • 2013 - 2016
    Investigations into the pain relief properties of Komipharm's test compound
    UniQuest Pty Ltd
    Open grant
  • 2013 - 2014
    Novel analgesics for improved treatment of chronic cancer pain
    Queensland Emory Development Alliance
    Open grant
  • 2013 - 2015
    Oral EMA401 mode of action study in a rat model of post-herpetic neralgia (PHN)
    Spinifex Pharmaceuticals Pty Ltd
    Open grant
  • 2013 - 2018
    Efficacy Profiling Innovation in Novel Pain Therapeutics Discovery
    ARC Linkage Projects
    Open grant
  • 2011 - 2014
    Therapeutic Innovation Australia - Queensland node (Source of funds: EIF)
    Therapeutic Innovation Australia Limited
    Open grant
  • 2011 - 2015
    Translating health discoveries into products
    Queensland Government Smart Futures Co-Investment Fund
    Open grant
  • 2010 - 2012
    Development of high throughput in-vitro test methods for screening sensitization potential of industrial chemicals
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2010 - 2013
    Novel polymeric microparticles for slow-release intrathecal delivery of analgesics
    ARC Linkage Projects
    Open grant
  • 2010 - 2013
    Development of chaperonin 10-based second generation biopharmaceuticals for treatment of inflammatory diseases
    ARC Linkage Projects
    Open grant
  • 2010
    Cost effective acquisition of an LC-MS/MS system to support CIPDD organics analysis and preclinical and clinical operations
    UQ Major Equipment and Infrastructure
    Open grant
  • 2010
    High content imaging analysis for bioactive and novel therapeutic target evaluation
    UQ Major Equipment and Infrastructure
    Open grant
  • 2009 - 2010
    Systematic evaluation of whether in vitro methods can predict in vivo opioid analgesic efficacy, safety and teolerability
    Alchemia Pty Ltd
    Open grant
  • 2009 - 2013
    Alzheimer's disease: Novel MRI Biomarkers for Clinical Diagnosis and Translational Studies
    Queensland Government Smart State National and International Research Alliances Program
    Open grant
  • 2009
    Robotics Instrumentation for High Throughput Sample preparation for Increased Productivity of the CIPDD/TetraQ's HPLC-MS/MS Systems for Quantitative Analysis of Organics in a Quality Systems NATA-Acc
    UQ Faculty Co-Funding
    Open grant
  • 2008
    Investigation of the relationship between cytokine levels and opioid analgesics in patients with chronic non-cancer pain receiving long term intrathecal opioid therapy for pain management
    Gallipoli Research Foundation
    Open grant
  • 2008
    Novel therapeutic for treating painful diabetic neuropathy
    Diabetes Australia Research Trust
    Open grant
  • 2006 - 2007
    Investigation of whether a small dose of Oxycodone enhances the efficacy and/or tolerability of orally administered pregabalin in patients with either post-herpetic neuralgia (PHN) or painful diabetic
    Gallipoli Research Foundation
    Open grant
  • 2006 - 2009
    Systematic evaluation of whether in vitro methods can predict in vivo opioid analgesic efficacy, safety and tolerability
    ARC Linkage Projects
    Open grant
  • 2006
    Advanced Cell Labelling and Imaging Facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2005
    NHMRC_Equipment Grant = DSI Telemetry System
    NHMRC Equipment Grant
    Open grant
  • 2004 - 2005
    The analgesic evaluation of novel natural products from the Australian plant Barringtonia acutangula
    Griffith University
    Open grant
  • 2004 - 2005
    NHMRC_Equipment Grant_HLTH_Pharmacy
    NHMRC Equipment Grant
    Open grant
  • 2004
    Synthesis And Pharmacological Evaluation Of Strong Opioid Analgesics With Improved Side-Effect Profiles
    University of Queensland Research Development Grants Scheme
    Open grant
  • 2003
    Evaluation Of Intravenous Oxycodone As An Analgesic In Dogs: Pharmacodynamic/Pharmacokinetic And Dose Ranging Studies
    University of Queensland Research Development Grants Scheme
    Open grant
  • 2003
    Malvern Zetasizer 3000HS
    NHMRC Equipment Grant
    Open grant
  • 2002 - 2003
    Pharmacological investigation of the toxicological effects of high doses of systemic morphine
    Queensland Cancer Fund
    Open grant
  • 2001 - 2002
    Prevention of chronic complications in the STZ-diabetic rat
    Mayne Bequest Fund
    Open grant
  • 2001 - 2004
    Lipid and liposaccharide based drug delivery systems
    Wellcome Trust
    Open grant
  • 2001
    A biohazard laminar flow hood for neuronal cell cultures:partial cost recovery from emergency purchase
    Brain Research Fund
    Open grant
  • 2001
    Neuro-excitatory side-effects of high-dose systemic morphine in cancer patients: mechanistic studies.
    Cancer Bequest Fund
    Open grant
  • 1999 - 2002
    A novel liposaccharide based system for drug/peptide delivery
    Wellcome Trust
    Open grant
  • 1999
    The use of fluorescence microscopy to investigate the role of the calcium pump in disease and the mechanism of excitatory side effects by high dose morphine
    Ramaciotti Foundation
    Open grant
  • 1998 - 1999
    Further investigation of morphine 3-glucuronide's role in the dose-limiting excitatory side-effects of morphine administered chronically to cancer patients
    Queensland Cancer Fund
    Open grant
  • 1998 - 2000
    M3G: Further Studies of its CNS Pharmacology
    NHMRC Project Grant
    Open grant

Supervision

Availability

Emeritus Professor Maree Smith is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Pathobiology of Neuropathic (nerve damage) Pain

  • Novel neuropathic pain therapeutics discovery

  • Painful Diabetic Neuropathy: Towards Improved Drug Treatments

Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Emeritus Professor Maree Smith directly for media enquiries about:

  • Bioanalysis - drugs
  • Clinical trials - drug development
  • Drug analysis
  • Drug development
  • Efficacy models - pharmacology
  • Opioid pharmacology
  • Pain management - pharmacy
  • Pharmacokinetics
  • Pharmacology
  • Pharmacy
  • Preclinical drug development
  • Preclinical efficacy models

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