Professor Jason Roberts
Professor

Jason Roberts

Email: 
Phone: 
+61 7 334 66074

Background

Professor Jason Roberts is Director of the University of Queensland Centre for Clinical Research (UQCCR), an Australian National Health and Medical Research Council (NHMRC) Leadership Fellow L2 at The University of Queensland. He is also a Consultant Clinical Pharmacist at the Royal Brisbane and Women’s Hospital and Interim Director of the Herston Infectious Diseases Institute (HeIDI). He is Director of the NHMRC-funded Centre for Research Excellence RESPOND which is based at UQCCR. He is a clinician-scientist with a strong interest in research and his principal research theme is optimization of antimicrobial dosing in the critically ill. Prof Roberts has authored over 650 published papers and book chapters on this topic, has been awarded over $55 million in grants and has supervised >20 PhD students to completion.

Prof Roberts was recognised as Australia’s leading researcher in two separate categories, Critical Care and Communicable Diseases, by the Australian’s 2019 Research Magazine.

He has been invited to present his results at major international conferences in critical care, infectious diseases, pharmacy, nephrology, transplant and safety. He has served on the Critical Review Panel for ATS/IDSA Guidelines of HAP, HCAP and VAP and the Australian Therapeutic Guidelines - Antibiotic and the 2021 Surviving Sepsis Guidelines. He is the Past Chair of the Working Group for Antimicrobial Use in ICU for the European Society of Intensive Care Medicine and an Executive Member of the PK/PD Group (EPASG) within the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).

He is Section Editor for the International Journal of Antimicrobial Agents and an Associate Editor of the Journal or Pharmacy Practice and Research, the journal for the Society of Hospital Pharmacists of Australia and an Associate Editor for Pharmacotherapy and Aanesthesiology Pain and Critical Care Medicine journal. He has convened >50 seminars/conferences including being co-convenor for Medicines Management 2013, The National Conference for Society of Hospital Pharmacists of Australia.

He also engages with Industry to perform studies that develop optimised antibiotic dosing regimens that maximise antibiotic efficacy for testing in clinical trials or for use in special patient populations (e.g. critically ill, pneumonia, dialysis).

Availability

Professor Jason Roberts is:
Available for supervision
Media expert

Fields of research

Clinical sciences Pharmacology and pharmaceutical sciences

Qualifications

  • Bachelor (Honours), University of Sydney
  • Doctor of Philosophy, The University of Queensland
  • Society of Hospital Pharmacists of Australia, Society of Hospital Pharmacists of Australia

Search Professor Jason Roberts’s works on UQ eSpace

837 works between 1989 and 2025
All (837) Journal Article (755) Book Chapter (26) Conference Publication (49) Book (2) Other Outputs (5)

341 - 360 of 837 works

2020

Journal Article

Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations

Xie, Jiao, Roberts, Jason A., Lipman, Jeffrey, Cai, Yan, Wang, Haitao, Zhao, Nuannuan, Xu, Xiaona, Yang, Shan, Li, Youjia and Zhang, Kanghuai (2020). Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations. International Journal of Antimicrobial Agents, 55 (6) 105943, 105943. doi: 10.1016/j.ijantimicag.2020.105943

Pharmacokinetic/pharmacodynamic adequacy of polymyxin B against extensively drug-resistant Gram-negative bacteria in critically ill, general ward and cystic fibrosis patient populations

2020

Other Outputs

Pharmacokinetics-Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: a Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents

Zeitlinger, Markus, Koch, Birgit CP, Brüggemann, Roger, De Cock, Pieter, Felton, Timothy, Hites, Maya, Le, Jennifer, Luque, Sonia, MacGowan, Alasdair, Marriott, Deborah, Muller, Anouk E, Nadrah, Kristina, Paterson, David, Standing, Joseph F., Telles, João P., Wölfl-Duchek, Michael, Thy, Michael and Roberts, Jason A. (2020). Pharmacokinetics-Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: a Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents. doi: 10.2139/ssrn.3561236

Pharmacokinetics-Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: a Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents

2020

Journal Article

A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration

Sime, Fekade B., Lassig-Smith, Melissa, Starr, Therese, Stuart, Janine, Pandey, Saurabh, Parker, Suzanne L., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2020). A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration. Antimicrobial Agents and Chemotherapy, 64 (1) e01655. doi: 10.1128/aac.01655-19

A population pharmacokinetic model-guided evaluation of ceftolozane/tazobactam dosing in critically ill patients undergoing continuous venovenous hemodiafiltration

2020

Conference Publication

Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients.

Scuderi, C., Parker, S., John, G., McWhinney, B., Ungerer, J., Mallett, A., Roberts, J., Healy, H. and Staatz, C.E. (2020). Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients. . RBWH Symposium, Brisbane, QLD Australia, 7-11 December 2020.

Interest in possible alternative methods to venepuncture-based monitoring in kidney transplant patients.

2020

Conference Publication

The DECISIVE study: defining beta-lactam concentration in intensive care unit patients – the pharmacokinetics of piperacillin and meropenem in critically ill patients with conserved renal function

Abdul-Aziz, M., Rozali, M., Othman-Jailani, M., Rahman, A. Abd, Sulaiman, H., Atiya, N., Adiraju, S., Wallis, S., Mat, W. Wan, Mazlan, M., Jamaluddin, M., Hasan, M., Mat-Nor, M. and Roberts, J. (2020). The DECISIVE study: defining beta-lactam concentration in intensive care unit patients – the pharmacokinetics of piperacillin and meropenem in critically ill patients with conserved renal function. 31st ICC - 4th GCCMID 2019, Dubai, United Arab Emirates, 6 - 9 November 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.jiph.2020.01.129

The DECISIVE study: defining beta-lactam concentration in intensive care unit patients – the pharmacokinetics of piperacillin and meropenem in critically ill patients with conserved renal function

2019

Journal Article

Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study

Raby, Edward, Naicker, Saiyuri, Sime, Fekade Bruck, Manning, Laurens, Wallis, Steven C., Pandey, Saurabh and Roberts, Jason A. (2019). Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study. European Journal of Hospital Pharmacy, 27 (e1) e19002093, e84-e86. doi: 10.1136/ejhpharm-2019-002093

Ceftolozane–tazobactam in an elastomeric infusion device for ambulatory care: an in vitro stability study

2019

Journal Article

Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion

Dhaese, S.A.M., Colin, P., Willems, H., Heffernan, A., Gadeyne, B., Van Vooren, S., Depuydt, P., Hoste, E., Stove, V., Verstraete, A.G., Lipman, J., Roberts, J.A. and De Waele, J.J. (2019). Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion. International Journal of Antimicrobial Agents, 54 (6), 741-749. doi: 10.1016/j.ijantimicag.2019.08.024

Saturable elimination of piperacillin in critically ill patients: implications for continuous infusion

2019

Journal Article

Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN)

Ranganathan, Dwarakanathan, Abdul-Aziz, Mohd H., John, George T., McWhinney, Brett C., Fassett, Robert G., Healy, Helen, Kubler, Paul, Lim, Aaron, Lipman, Jeffrey, Purvey, Megan, Roberts, Matthew, Reyaldeen, Reza, Ungerer, Jacobus and Roberts, Jason A. (2019). Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN). Therapeutic Drug Monitoring, 41 (6), 703-713. doi: 10.1097/ftd.0000000000000658

Pharmacokinetics of enteric coated mycophenolate sodium in lupus nephritis (POEMSLUN)

2019

Journal Article

Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium

Leone, Marc, Roberts, Jason A., Bassetti, Matteo, Bouglé, Adrien, Lavigne, Jean-Philippe, Legrand, Matthieu, Neely, Michael, Paiva, José-Artur, Payen, Didier, Rello, Jordi, Roger, Claire, Sjövall, Fredrik and Jung, Boris (2019). Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium. Anaesthesia Critical Care and Pain Medicine, 38 (6), 647-656. doi: 10.1016/j.accpm.2019.09.009

Update in antibiotic therapy in intensive care unit: report from the 2019 Nîmes International Symposium

2019

Journal Article

Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial

Breilh, Dominique, Honore, Patrick M., De Bels, David, Roberts, Jason A., Gordien, Jean Baptiste, Fleureau, Catherine, Dewitte, Antoine, Coquin, Julien, Roze, Hadrien, Perez, Paul, Attou, Rachid, Redant, Sebastien, Kugener, Luc, Saux, Marie-Claude, Spapen, Herbert D., Ouattare, Alexandre and Joannes-Boyau, Olivier (2019). Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial. Journal of Translational Internal Medicine, 7 (4), 155-169. doi: 10.2478/jtim-2019-0031

Pharmacokinetics and pharmacodynamics of anti-infective agents during continuous veno-venous hemofiltration in critically ill patients: lessons learned from an ancillary study of the IVOIRE trial

2019

Journal Article

Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity

Luque, Sonia, Muñoz-Bermudez, Rosana, Echeverría-Esnal, Daniel, Sorli, Luisa, Campillo, Nuria, Martínez-Casanova, Javier, González-Colominas, Elena, Álvarez-Lerma, Francisco, Horcajada, Juan Pablo, Grau, Santiago and Roberts, Jason A. (2019). Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity. Therapeutic Drug Monitoring, 41 (6), 732-739. doi: 10.1097/FTD.0000000000000665

Linezolid dosing in patients with liver cirrhosis: standard dosing risk toxicity

2019

Journal Article

Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)

Tabah, Alexis, Bassetti, Matteo, Kollef, Marin H., Zahar, Jean-Ralph, Paiva, José-Artur, Timsit, Jean-Francois, Roberts, Jason A., Schouten, Jeroen, Giamarellou, Helen, Rello, Jordi, De Waele, Jan, Shorr, Andrew F., Leone, Marc, Poulakou, Garyphallia, Depuydt, Pieter and Garnacho-Montero, Jose (2019). Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP). Intensive Care Medicine, 46 (2), 245-265. doi: 10.1007/s00134-019-05866-w

Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP)

2019

Journal Article

Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?

Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?. Current Opinion in Anaesthesiology, 33 (1), 1-82. doi: 10.1097/aco.0000000000000810

Antibiotic dosing during extracorporeal membrane oxygenation: does the system matter?

2019

Journal Article

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

Parker, Suzanne L., Pandey, Saurabh, Sime, Fekade B., Lipman, Jeffrey, Roberts, Jason A. and Wallis, Steven C. (2019). A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study. Analytical and Bioanalytical Chemistry, 411 (29), 7831-7840. doi: 10.1007/s00216-019-02184-4

A validated LC-MSMS method for the simultaneous quantification of meropenem and vaborbactam in human plasma and renal replacement therapy effluent and its application to a pharmacokinetic study

2019

Journal Article

Attainment of therapeutic vancomycin level within the first 24 h: authors' response

Baptista, João Pedro, Roberts, Jason A., Sousa, Eduardo, Freitas, Ricardo, Devesa, Nuno and Pimentel, Jorge (2019). Attainment of therapeutic vancomycin level within the first 24 h: authors' response. Critical Care, 23 (1) 354, 354. doi: 10.1186/s13054-019-2639-7

Attainment of therapeutic vancomycin level within the first 24 h: authors' response

2019

Journal Article

Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study

Pandey, Saurabh, Dhanani, Jayesh, Lipman, Jeffrey, Roberts, Jason A., Wallis, Steve C. and Parker, Suzanne L. (2019). Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study. Clinical Chemistry and Laboratory Medicine, 58 (2), 274-284. doi: 10.1515/cclm-2019-0780

Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study

2019

Journal Article

Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report

Dhanani, Jayesh A., Lipman, Jeffrey, Pincus, Jason, Townsend, Shane, Livermore, Amelia, Wallis, Steven C., Abdul-Aziz, Mohd H. and Roberts, Jason A. (2019). Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report. Chemotherapy, 64 (3), 1-4. doi: 10.1159/000502474

Pharmacokinetics of total and unbound cefazolin during veno-arterial extracorporeal membrane oxygenation: a case report

2019

Journal Article

Amikacin initial dose in critically ill patients: a nonparametric approach to optimize a priori pharmacokinetic/pharmacodynamic target attainments in individual patients

Boidin, Clément, Bourguignon, Laurent, Cohen, Sabine, Roger, Claire, Lefrant, Jean-Yves, Roberts, Jason A., Allaouchiche, Bernard, Lepape, Alain, Friggeri, Arnaud and Goutelle, Sylvain (2019). Amikacin initial dose in critically ill patients: a nonparametric approach to optimize a priori pharmacokinetic/pharmacodynamic target attainments in individual patients. Antimicrobial Agents and Chemotherapy, 63 (11) e00993-19, e00993-19. doi: 10.1128/aac.00993-19

Amikacin initial dose in critically ill patients: a nonparametric approach to optimize a priori pharmacokinetic/pharmacodynamic target attainments in individual patients

2019

Journal Article

Pharmacokinetics of flucloxacillin during prolonged intermittent renal replacement therapy in a 76-year-old man

Fox, Emma, Cheng, Vesa, Rawlins, Matthew, Dyer, John, De Keulenaer, Bart, Page, Michael M., Hoad, Kirsten and Roberts, Jason (2019). Pharmacokinetics of flucloxacillin during prolonged intermittent renal replacement therapy in a 76-year-old man. Journal of Chemotherapy, 31 (7-8), 1-5. doi: 10.1080/1120009X.2019.1681622

Pharmacokinetics of flucloxacillin during prolonged intermittent renal replacement therapy in a 76-year-old man

2019

Other Outputs

Development of population and Bayesian models for applied use in patients receiving cefepime

Liu, Jiajun, Neely, Michael, Lipman, Jeffrey, Sime, Fekade, Roberts, Jason, Kiel, Patrick J, Avedissian, Sean N., Rhodes, Nathaniel J. and Scheetz, Marc H. (2019). Development of population and Bayesian models for applied use in patients receiving cefepime. doi: 10.1101/19009647

Development of population and Bayesian models for applied use in patients receiving cefepime

Current funding

  • 2025 - 2027
    Beta-lactam Antibiotic Infusions in Septic Critically Ill Children - A Pilot Randomised Controlled Trial (BUILD)
    Intensive Care Foundation
    Open grant
  • 2025 - 2030
    Comparison of Beta-Lactam Antibiotic Infusions in Septic Critically Ill Children: The BUILD Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2025 - 2030
    Comparison of Continuous and Extended vs Intermittent Beta-Lactam Infusions in Critically Ill Children with Sepsis ¿ the BUILD Multicentre Binational Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2025 - 2029
    ROAD RCT: Resistance Optimised Antibiotic Dosing in critically ill patients - a Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2025 - 2029
    ROAD RCT: Resistance Optimised Antibiotic Dosing in critically ill patients - a Randomised Controlled Trial
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2024 - 2025
    Determining bEta-lactam Exposure targets in Patients with deep-seated infections. The DEEP Study (an observational PK-PD pilot study) (TPCHF Common Good Grant led by Metro North HHS)
    Metro North Hospital and Health Service
    Open grant
  • 2024 - 2025
    Establishing the pharmacokinetic profiles of Elexacaftor, Tezacaftor & Ivacaftor (Trikafta) in patients with Cystic Fibrosis to allow for therapeutic drug monitoring
    Open grant
  • 2024 - 2028
    Unlocking the gut microbiome to track the spread of AMR genes and pathogens
    MRFF - Global Health Initiative
    Open grant
  • 2023 - 2028
    OPTIMAL: OPTimising Immunoglobulin Management in Australia (NHMRC 2023 CRE administered by Monash University)
    Monash University
    Open grant
  • 2023 - 2026
    Fentanyl use by nebuliser in labour - the FUN Study (ANZCA Grant led by MNHHS)
    Metro North Hospital and Health Service
    Open grant
  • 2023 - 2025
    A prospective observational comparative plasma and cerebrospinal fluid pharmacokinetics of levetiractam in aneursymal subarachoid haemorrhage and traumatic brain injury (The ALLEVIATE STUDY)
    Metro North Hospital and Health Service
    Open grant
  • 2023 - 2028
    Building the next mRNA vaccines and therapies
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2023 - 2026
    Pharmacogenomics for better treatment of fungal infections in cancer
    MRFF Quality, Safety and Effectiveness of Medicine Use and Medicine Intervention by Pharmacists
    Open grant
  • 2022 - 2026
    A coordinated multiplatform randomised trial for hospitalised patients with COVID-19 (Led by Monash University)
    Monash University
    Open grant
  • 2022 - 2025
    Parkinson's Disease Bequest - Collaborative proposal, RN support
    Research Donation Generic
    Open grant
  • 2022 - 2026
    Translating precision antibiotic dosing into better outcomes for severe infections
    NHMRC Investigator Grants
    Open grant
  • 2021 - 2026
    Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
    NHMRC Centres of Research Excellence
    Open grant
  • 2021 - 2025
    Pharmacokinetics of antimicrobials in paediatric patients on extracorporeal therapies (APET-PK)
    Children's Health Queensland Hospital and Health Service
    Open grant
  • 2021 - 2026
    Testing a sinonasal microbiome transplant as a therapy for Chronic Rhinosinusitis by randomised controlled trial
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2021 - 2025
    OctapeptinX Potentiators to treat XDR Gram-negative infections
    NHMRC Development Grant
    Open grant
  • 2019 - 2025
    Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMAT)
    Cystic Fibrosis Foundation USA
    Open grant
  • 2018 - 2025
    Multi-drug resistant non-tuberculous mycobacteria infection research
    Research Donation Generic
    Open grant
  • 2018 - 2025
    A platform clinical trial approach to the management of Mycobacterium abscessus complex (MABSC)
    NHMRC MRFF - Lifting Clinical Trials Registries Capacity
    Open grant

Past funding

  • 2024 - 2025
    Optimising intraoperative coagulation management for precision vascular surgey (externally administered by Metro North Health and Hospital Service)
    Metro North Hospital and Health Service
    Open grant
  • 2023 - 2024
    Development and clinical integration of a novel precision dosing software application to improve antimicrobial dosing in critically ill patients
    Heidi-CSIRO IDR and AMR Projects
    Open grant
  • 2023
    Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU Study
    Gilead Australia Fellowship
    Open grant
  • 2022 - 2023
    CAPJI RETRO-Research Support
    Metro North Hospital and Health Service
    Open grant
  • 2022 - 2023
    Pharmacokinetic profile and breastmilk excretion of sugammadex in pregnant women (ANZCA grant administered by Metro North HHS)
    Metro North Hospital and Health Service
    Open grant
  • 2022 - 2023
    Prospective, Open-Label, Randomized Control Trial on Pharmacokinetics of Direct Oral Anticoagulant (Apixaban) in Prevention of Primary Nephrotic Syndrome Associated Thromboembolic Disease (RBWH admin)
    Metro North Hospital and Health Service
    Open grant
  • 2022 - 2023
    Evaluation of the stability of Aciclovir in elastomeric infusion devices used for Outpatient Parenteral Antimicrobial Therapy in accordance with the requirement of the UK NHS Yellow Cover Document
    British Society for Antimicrobial Chemotherapy
    Open grant
  • 2022 - 2023
    The effects of renal replacement therapy on immunosuppressive drug concentrations (RWBH and RBWH Foundation Research Project Grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2022 - 2023
    CT-Perfusion for neurological diagnostic evaluation: a prospective Canadian multicenter diagnostic test study
    Centre Hospitalier de l'Universite de Montreal
    Open grant
  • 2022
    Comparative pharmacokinetics of nebulised and intravenous ketamine and dexmedetomidine in ventilated patients
    Australian and New Zealand College of Anaesthestists
    Open grant
  • 2021 - 2023
    Continuous vs intermittent infusion of beta-lactam antibacterial drugs: impact on resistance and outcomes in sepsis - PMWP 170
    United States Food and Drug Administration
    Open grant
  • 2021 - 2022
    A prospective observational study to describe the population pharmacokinetics of olanzapine and quetiapine in critically ill patients with delirium (PARANOID)
    Melbourne Health
    Open grant
  • 2021
    Evaluation of the stability of Aciclovir in elastomeric infusion devises used in Outpatient Parenteral Antimicrobial Therapy in accordance with the requirement of the UK NHS Yellow Cover Document
    British Society for Antimicrobial Chemotherapy
    Open grant
  • 2021 - 2022
    Evaluation of the stability of Amoxicillin in elastomeric infusion devices used for Outpatient Parenteral Antimicrobial Therapy in accordance with the requirement of the UK NHS Yellow Cover Document
    British Society for Antimicrobial Chemotherapy
    Open grant
  • 2021 - 2022
    PIMS Study: An investigation of the utility of Microsampling versus traditional blood sampling for antibiotic pharmacokinetics in Children (SCHS Wishlist Foundation grant administered by SCHHS
    Sunshine Coast Hospital and Health Service
    Open grant
  • 2021
    Optimising Cefazolin and Ceftriaxone Dosing in Australian Indigenous patients Requiring Intermittent Haemodialysis (Collaborative Research Project led by Flinders University)
    Flinders University
    Open grant
  • 2021 - 2022
    Optimising dosing regimens of antimicrobials in critically ill children on extracorporeal membrane oxygenation (ECMO)
    Preclinical and Clinical Early Career Research
    Open grant
  • 2020 - 2021
    The effect of extracorporeal membrane oxygenation (ECMO) on the effectiveness of Coronavirus Disease 2019 (COVID-19) pharmacotherapy - ex vivo characterisation and quantification [...]
    Metro North Hospital and Health Service
    Open grant
  • 2020 - 2021
    Evaluation of the stability of Temocillin in elastomeric infusion devices used for Outpatient Parenteral Antimicrobial Therapy in accordance with the requirement of the UK NHS Yellow Cover Document
    British Society for Antimicrobial Chemotherapy
    Open grant
  • 2020
    Dose optimization and clinical drug testing for Ivermectin
    Monash University
    Open grant
  • 2020 - 2024
    Optimising antibiotic dosing for critically ill patients
    Queensland Advancing Clinical Research Fellowship
    Open grant
  • 2020 - 2021
    USE OF THERAPEUTIC DRUG MONITORING (TDM) TO OPTIMISE ORAL/ENTERAL HYDROXYCHLOROQUINE DOSING IN CRITICALLY ILL PATIENTS WITH COVID-19 (MRFF CRR Respiratory Medicine administered by QUT)
    Queensland University of Technology
    Open grant
  • 2020
    Rapid detection of resistance genes from Gram-negative bacteria isolated from blood in ICU-admitted patients
    Pathology Queensland - Study, Education & Research Trust Fund
    Open grant
  • 2020 - 2022
    The development of novel pharmacokinetic techniques to optimise treatment and reduce antimicrobial resistance for sexually transmitted infections (STIs). (2020 NHMRC Ideas Grant led by UoM)
    University of Melbourne
    Open grant
  • 2019 - 2021
    Screening anti-fungal exposure in intensive care unit
    European Society of Clinical Microbiology and Infectious Diseases Study Group Research Grant
    Open grant
  • 2019 - 2021
    Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients (Led by MNHHS)
    Metro North Hospital and Health Service
    Open grant
  • 2019
    Establishing UQ Centre for Clinical Research as the centre for Aerosol therapy in critical care by optimising particle size of aerosols for effective drug delivery.
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2024
    Novel dosing regimens to maximise antibiotic effectiveness for treatment of pneumonia in the intensive care unit
    NHMRC Project Grant
    Open grant
  • 2019 - 2020
    Optimising the treatment of invasive infection in critically ill neonates, through application of an innovative microsampling approach
    Metro North Hospital and Health Service
    Open grant
  • 2019
    Pharmacokinetic and statistical analysis of data from Screening Anti-Fungal Exposure in Intensive Care Units (SAFE-ICU) study
    Metro North Hospital and Health Service
    Open grant
  • 2018 - 2020
    Measuring aspirin penetration into synovial fluid to assess its potential for prevention of prosthetic joint infection
    Study, education and research trust account
    Open grant
  • 2018 - 2019
    An in vitro study of the stability of ceftolozane-tazobactam in elastomeric infusor devices for ambulatory care
    South Metropolitan Health Service
    Open grant
  • 2018 - 2021
    Advanced treatment of infectious diseases for critically ill children, through innovation in blood sampling
    The Children's Hospital Foundation
    Open grant
  • 2018
    Antimicrobial pharmacokinetics in critically ill adults during sustained low efficiency dialysis (SLED)
    Ottawa Hospital Research Institute
    Open grant
  • 2018 - 2019
    Can software optimise antibiotic dosing in critically ill patients?
    Metro North Hospital and Health Service
    Open grant
  • 2018
    Effect of albumin resuscitation on drug pharmacokinetics in low protein and LPS challenged sheep
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2018 - 2019
    Innovative blood sampling to reduce the burden of long-term treatment for kidney transplant recipients
    Metro North Hospital and Health Service
    Open grant
  • 2018
    Ion Mobility Separation of Challenging Clinical Samples
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2021
    Lipopeptide antibiotics for XDR Gram-negative infections
    NHMRC Development Grant
    Open grant
  • 2018 - 2019
    Nuclear medicine suite for animals
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2019
    Pharmacokinetic-pharmacodynamic substudy of patients with severe sepsis randomised to receive beta-lactam antibiotics by either intermittent or continuous infusion.
    Metro North Hospital and Health Service
    Open grant
  • 2018
    Rapid characterisation of pathogens for personalised antimicrobial selection in critically ill patients
    Metro North Hospital and Health Service
    Open grant
  • 2017 - 2018
    Assay development for therapeutic drug monitoring of ceftolozane-tazobactam
    Merck Sharp & Dohme Australia
    Open grant
  • 2017 - 2019
    A prospective observational pharmacokinetic evaluation of the plasma and cerebrospinal fluid concentrations of a single dose ceftolozane/tazobactam in infected critically ill patients with an ...
    Merck Sharp & Dohme Australia
    Open grant
  • 2017 - 2021
    BLING III: A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent betalactam dosing in... (NHMRC Project Grant led by the University of New South Wales)
    University of New South Wales
    Open grant
  • 2017 - 2018
    Does routine antibiotic administration in overweight women having elective caesarean section achieve therapeutic levels?
    Metro North Hospital and Health Service
    Open grant
  • 2017 - 2018
    Pharmacokinetic-pharmacodynamic substudy of patients with severe sepsis randomised to receive beta-lactam antibiotics by either intermittent or continuous infusion
    Royal Brisbane and Women's Hospital Foundation
    Open grant
  • 2017 - 2021
    Redefining antibiotic dosing to reduce bacterial resistance
    NHMRC Practitioner Fellowships
    Open grant
  • 2017 - 2018
    Screening Anti-Fungal Exposure in Intensive Care Units: The SAFE-ICU study
    Metro North Hospital and Health Service
    Open grant
  • 2016 - 2018
    Using a drop of blood to personalise antibiotic dosing in children and prevent antibiotic resistance
    Ian Potter Foundation
    Open grant
  • 2016
    Pharmacokinetic/Pharmacodynamic (PK/PD) analysis of antimicrobials in renal replacement therapy (RRT) and septic shock
    University Hospital of Nîmes
    Open grant
  • 2016 - 2018
    Single dose population pharmacokinetics of intravenous posaconazole in critically ill patients
    Merck Sharp & Dohme Australia
    Open grant
  • 2016 - 2019
    An observational pharmacokinetic study of ceftolozane-tazobactam in intensive care unit patients with and without continuous renal replacement therapy
    Merck Sharp & Dohme Australia
    Open grant
  • 2016 - 2017
    Does inhaled tobramycin distribute effectively into the lungs? A comparative study using radiolabelled tobramycin.
    Royal Brisbane and Women's Hospital
    Open grant
  • 2016 - 2019
    Novel membrane-targeted antibiotics against drug-resistant Gram-positive bacterial infections
    NHMRC Development Grant
    Open grant
  • 2016
    Optimising ceftriaxone dosing for critically ill patients with severe pneumonia
    Royal Brisbane and Women's Hospital
    Open grant
  • 2015 - 2021
    Centre for REdefining antibiotic use to reDUce resistanCE and prolong the lives of antibiotics (REDUCE)
    NHMRC Centres of Research Excellence
    Open grant
  • 2015 - 2016
    A preliminary investigation of the pharmacokinetics and pharmacodynamics of amikacin/fosfomycin combination against Acinetobacter baumannii using a dynamic in vitro hollow-fibre infection model
    Cardeas Pharma Corporation
    Open grant
  • 2015
    Pharmacokinetic Australasian Collaborative
    Intensive Care Foundation
    Open grant
  • 2015
    Addressing an unmet need by establishing a state-of-the-art translational model at UQ: The hollow fibre in vitro infection model
    UQ Major Equipment and Infrastructure
    Open grant
  • 2015
    Incidence, risk factors, consequences and treatment of ventilated patients with nosocomial infection with pandrug resistant organisms in hospitals in Asia
    UWA-UQ Bilateral Research Collaboration Award
    Open grant
  • 2015
    Optimising Benzylpenicillin dosing for critically ill patients with severe pneumonia
    Royal Brisbane and Women's Hospital
    Open grant
  • 2014 - 2021
    Centre for Research Excellence in Advanced Cardio-respiratory Therapies Improving OrgaN Support (ACTIONS)
    NHMRC Centres of Research Excellence
    Open grant
  • 2014 - 2015
    Dose optimisation of fluconazole in critically ill
    Royal Brisbane and Women's Hospital
    Open grant
  • 2014 - 2017
    Innovative dosing approaches to maximise bacterial killing and prevent resistance in septic critically ill patients
    NHMRC Project Grant
    Open grant
  • 2014 - 2018
    Randomised controlled study of an intense short course of optimised combination therapy versus conventional therapy for the management of Gram-negative bacteraemia
    Merck Sharp & Dohme Australia Grant for Pharmacotherapeutics in Infectious Diseases
    Open grant
  • 2014
    Strenghtening the School of Medicine's position as a central coordinator of global pharmacokenetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2015
    DALI - Defining Antibiotic Levels in Intensive care unit patients
    University Hospital of Nîmes
    Open grant
  • 2013 - 2016
    NHMRC Career Development Fellowship (Clinical; Level 1): Antibiotic optimisation for severely ill patients
    NHMRC Career Development Award
    Open grant
  • 2013 - 2014
    Pharmacokinetics of cephalosporin antibiotics in peritoneal dialysis with peritonitis
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013
    Antibiotic Absorption and Clearance during Renal Replacement Therapy: An ex vivo study
    UQ Early Career Researcher
    Open grant
  • 2013 - 2015
    Are modern methods for aminoglycoside monitoring superior to existing approaches? A randomised controlled trial
    Royal Brisbane and Women's Hospital
    Open grant
  • 2013 - 2016
    Robust antibiotic dosing for critically ill patients receiving renal replacement therapy
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    A phase IIb randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients with severe sepsis
    NHMRC Project Grant
    Open grant
  • 2012
    Facilitating School of Medicine as a central coordinator of global pharmacokinetic studies in critically ill patients
    UQ Major Equipment and Infrastructure
    Open grant
  • 2012 - 2014
    Non-Haemolytic Friulimicins for the Treatment of Multi-Drug Resistant Bacteria
    NHMRC Project Grant
    Open grant
  • 2012 - 2015
    Pilot Study of pharmacokinetic and pharmacodynamic assessment of monotherapy versus combination therapy for the management of gram negative bacteraemia
    Royal Brisbane and Women's Hospital
    Open grant
  • 2012 - 2015
    Prevention of Ventilator Associated Pneumonia by Inhaled Heparin
    Australian and New Zealand Intensive Care Foundation
    Open grant
  • 2011 - 2013
    Microdialysis to monitor fluid shifts and predict organ failure in the systemic inflammatory response syndrome
    UQ Collaboration and Industry Engagement Fund
    Open grant
  • 2011 - 2013
    Improving antibiotic dosing in critically ill patients with renal failure
    UQ Foundation Research Excellence Awards - DVC(R) Funding
    Open grant
  • 2011 - 2015
    Membrane-targeted antibiotic for the treatment of skin and lung infections caused by drug resistant pathogens including MRSA, VISA, VRE and S pneumoniae
    Wellcome Trust Seeding Drug Discovery
    Open grant
  • 2011 - 2014
    Effect of intravenous glutamine supplementation in trauma patients receiving enteral nutrition: A prospective double-blind randomised clinical trial
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2010 - 2011
    Pilot RCT of continuous beta-lactam infusion compared with intermittent dosing in critically ill patients
    Australian and New Zealand Intensive Care Foundation
    Open grant
  • 2010 - 2012
    Antibiotics in critically ill patients - dosage adjustments in renal failure and during continuous veno-venous haemodialysis
    Viertel Foundation (Sylvia and Charles Viertel)
    Open grant
  • 2010 - 2012
    Infection and survival imperative - the need for antibiotic dose optimisation in critically ill patients receiving dialysis
    Ramaciotti Foundation
    Open grant
  • 2010 - 2012
    Pharmacokinetics in continuous venovenous haemodiafiltration (CVVHDF) - using plasma and tissue antibiotic concentrations to optimise dosing of beta-lactam antibodies
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2010
    Infection imperative - the need for antibiotic dose optimisation in critically ill patients receiving dialysis
    UQ New Staff Research Start-Up Fund
    Open grant
  • 2009 - 2013
    NHMRC Training (Postdoctoral) Fellowship: Improving antibiotic dosing in hospitalised patients
    NHMRC Training (Postdoctoral) Fellowship
    Open grant
  • 2009 - 2014
    Assessment of the Microcirculation in Shocked Critically Unwell Patients during the first 24 hours of resuscitation
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2011
    Pharmacokinetics of Cephalothin, Vancomycin and Gentamicin Used for Antimicrobial Prophylaxis during elective abdominal aortic aneurysm surgery
    Australian & New Zealand College of Anaesthetists
    Open grant
  • 2009 - 2011
    Glomerular Hyperfiltration in at risk patients on Admission to the Intensive Care Unit (GHAU) Study
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2009 - 2014
    Inhaled Prophylactic-Heparin In Ventilator Associated Pneumonia Prevention Trial (IPHAPP)
    Royal Brisbane & Women's Hospital Research Foundation
    Open grant
  • 2008 - 2010
    Antibiotic dosing in the at risk critically ill patient
    NHMRC Project Grant
    Open grant
  • 2008
    Improved quantification of spatial and temporal changes in plasma and tissue drug levels and tissue pathology
    NHMRC Equipment Grant
    Open grant
  • 2006 - 2007
    Pharmacokinetic Modelling of Various B-lactam Antibiotics in Critically-ill Patients using Microdialysis
    Australian & New Zealand College of Anaesthetists
    Open grant

Availability

Professor Jason Roberts is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)

    Principal Advisor

    Other advisors: Dr Hafiz Abdul-Aziz, Honorary Professor Luregn Schlapbach

  • Doctor Philosophy

    Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)

    Principal Advisor

    Other advisors: Dr Fekade Sime

  • Doctor Philosophy

    Improving drug therapy for children with sepsis and life-threatening infections

    Principal Advisor

    Other advisors: Honorary Professor Luregn Schlapbach, Dr Sainath Raman

  • Doctor Philosophy

    Perioperative pharmacokinetics of surgical antibiotic prophylaxis

    Principal Advisor

    Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert

  • Doctor Philosophy

    Pharmacokinetics of anti-mycobacterial drugs in patients with cystic fibrosis

    Principal Advisor

    Other advisors: Professor Rachel Thomson, Professor Scott Bell

  • Doctor Philosophy

    How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles

    Principal Advisor

    Other advisors: Dr Mark Coulthard, Professor Jeffrey Lipman, Dr Xin Liu, Dr Patty Mitre

  • Doctor Philosophy

    Perioperative pharmacokinetics of surgical antibiotic prophylaxis

    Principal Advisor

    Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert

  • Doctor Philosophy

    Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.

    Principal Advisor

    Other advisors: Dr Fekade Sime

  • Doctor Philosophy

    Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing

    Principal Advisor

  • Doctor Philosophy

    What is the validity of altered dosing approaches for ensuring appropriate antibiotic dosing in the critically ill?

    Principal Advisor

  • Doctor Philosophy

    Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing

    Principal Advisor

  • Doctor Philosophy

    Suitability of ß-lactam and ß-lactamase inhibitor combinations for use in outpatient parenteral antimicrobial therapy

    Principal Advisor

    Other advisors: Dr Fekade Sime

  • Doctor Philosophy

    Precision antimicrobial dosing in infected critically ill patients

    Principal Advisor

  • Doctor Philosophy

    Designing and Implementing a Clinician-Led Protocol for Heparinisation Using Optimal Targets- anti Xa vs APTT

    Associate Advisor

    Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani

  • Doctor Philosophy

    Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models

    Associate Advisor

    Other advisors: Dr Fekade Sime

  • Doctor Philosophy

    Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients.

    Associate Advisor

    Other advisors: Professor Victoria Eley

  • Doctor Philosophy

    In vitro evaluation of the impact of different durations of exposure of fast-acting antimicrobials in combination with beta-lactams

    Associate Advisor

    Other advisors: Dr Fekade Sime

  • Doctor Philosophy

    Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)

    Associate Advisor

    Other advisors: Dr Fekade Sime

  • Doctor Philosophy

    The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation

    Associate Advisor

    Other advisors: Professor Bala Venkatesh

  • Doctor Philosophy

    Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models

    Associate Advisor

    Other advisors: Dr Fekade Sime

  • Doctor Philosophy

    Optimising antibiotic dosing for the treatment and prevention of central nervous system infections

    Associate Advisor

    Other advisors: Professor Jeffrey Lipman

  • Master Philosophy

    Designing and implementing a nurse-led electronic medical record (EMR) integrated heparinisation protocol using optimal targets (anti Xa vs APTT)

    Associate Advisor

    Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani

  • Doctor Philosophy

    Optimising the stability and dosing regimens of antibiotics for outpatient parenteral antibiotic therapy

    Associate Advisor

    Other advisors: Dr Fekade Sime

Completed supervision

Enquiries

Contact Professor Jason Roberts directly for media enquiries about:

  • Antibiotics
  • Drug dosage
  • Therapeutic drug monitoring

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