
Overview
Background
Professor Jason Roberts is Director of the University of Queensland Centre for Clinical Research (UQCCR), an Australian National Health and Medical Research Council (NHMRC) Leadership Fellow L2 at The University of Queensland. He is also a Consultant Clinical Pharmacist at the Royal Brisbane and Women’s Hospital and Interim Director of the Herston Infectious Diseases Institute (HeIDI). He is Director of the NHMRC-funded Centre for Research Excellence RESPOND which is based at UQCCR. He is a clinician-scientist with a strong interest in research and his principal research theme is optimization of antimicrobial dosing in the critically ill. Prof Roberts has authored over 650 published papers and book chapters on this topic, has been awarded over $55 million in grants and has supervised >20 PhD students to completion.
Prof Roberts was recognised as Australia’s leading researcher in two separate categories, Critical Care and Communicable Diseases, by the Australian’s 2019 Research Magazine.
He has been invited to present his results at major international conferences in critical care, infectious diseases, pharmacy, nephrology, transplant and safety. He has served on the Critical Review Panel for ATS/IDSA Guidelines of HAP, HCAP and VAP and the Australian Therapeutic Guidelines - Antibiotic and the 2021 Surviving Sepsis Guidelines. He is the Past Chair of the Working Group for Antimicrobial Use in ICU for the European Society of Intensive Care Medicine and an Executive Member of the PK/PD Group (EPASG) within the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).
He is Section Editor for the International Journal of Antimicrobial Agents and an Associate Editor of the Journal or Pharmacy Practice and Research, the journal for the Society of Hospital Pharmacists of Australia and an Associate Editor for Pharmacotherapy and Aanesthesiology Pain and Critical Care Medicine journal. He has convened >50 seminars/conferences including being co-convenor for Medicines Management 2013, The National Conference for Society of Hospital Pharmacists of Australia.
He also engages with Industry to perform studies that develop optimised antibiotic dosing regimens that maximise antibiotic efficacy for testing in clinical trials or for use in special patient populations (e.g. critically ill, pneumonia, dialysis).
Availability
- Professor Jason Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours), University of Sydney
- Doctor of Philosophy, The University of Queensland
- Society of Hospital Pharmacists of Australia, Society of Hospital Pharmacists of Australia
Works
Search Professor Jason Roberts’s works on UQ eSpace
2015
Journal Article
Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies
Sime, Fekade Bruck., Roberts, Michael S., Tiong, Ing Soo., Gardner, Julia H., Lehman, Sheila., Peake, Sandra L., Hahn, Uwe., Warner, Morgyn S. and Roberts, Jason A. (2015). Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies. Antimicrobial Agents and Chemotherapy, 59 (9), 5463-5469. doi: 10.1128/AAC.00389-15
2015
Journal Article
A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients
Carlier, Mieke, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2015). A simulation study reveals lack of pharmacokinetic/pharmacodynamic target attainment in de-escalated antibiotic therapy in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (8), 4689-4694. doi: 10.1128/AAC.00409-15
2015
Journal Article
Does appropriate antibiotic therapy mean only adequate spectrum and timing?
Lipman, Jeffrey and Roberts, Jason (2015). Does appropriate antibiotic therapy mean only adequate spectrum and timing?. Critical Care Medicine, 43 (8), 1773-1774. doi: 10.1097/CCM.0000000000001060
2015
Journal Article
The need for cost-effectiveness analyses of antimicrobial stewardship programmes: a structured review
Coulter, Sonali, Merollini, Katharina, Roberts, Jason A., Graves, Nicholas and Halton, Kate (2015). The need for cost-effectiveness analyses of antimicrobial stewardship programmes: a structured review. International Journal of Antimicrobial Agents, 46 (2) 4585, 140-149. doi: 10.1016/j.ijantimicag.2015.04.007
2015
Journal Article
Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?
Jamal, Janattul-Ain, Udy, Andrew A., Wallis, Steven C., Ranganathan, Dwarakanathan, McWhinney, Brett C., Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2015). Can we use an ex vivo continuous hemofiltration model to describe the adsorption and elimination of meropenem and piperacillin?. International Journal of Artificial Organs, 38 (8), 419-424. doi: 10.5301/ijao.5000422
2015
Journal Article
Enterovirus D68 disease and molecular epidemiology in Australia
Levy, Avram, Roberts, Jason, Lang, Jurissa, Tempone, Simone, Kesson, Alison, Dofai, Alfred, Daley, Andrew J., Thorley, Bruce and Speers, David J. (2015). Enterovirus D68 disease and molecular epidemiology in Australia. Journal of Clinical Virology, 69, 117-121. doi: 10.1016/j.jcv.2015.06.079
2015
Journal Article
Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review
Carlier, Mieke, Stove, Veronique, Wallis, Steven C., De Waele, Jan J., Verstraete, Alain G., Lipman, Jeffrey and Roberts, Jason A. (2015). Assays for therapeutic drug monitoring of β-lactam antibiotics: a structured review. International Journal of Antimicrobial Agents, 46 (4), 367-375. doi: 10.1016/j.ijantimicag.2015.06.016
2015
Journal Article
Standard dosing of amikacin and gentamicin in critically ill patients results in variable and subtherapeutic concentrations
Roger, Claire, Nucci, Bastian, Molinari, Nicolas, Bastide, Sophie, Saissi, Gilbert, Pradel, Gael, Barbar, Saber, Aubert, Clement, Lloret, Sophie, Elotmani, Loubna, Polge, Anne, Lefrant, Jean-Yves, Roberts, Jason A and Muller, Laurent (2015). Standard dosing of amikacin and gentamicin in critically ill patients results in variable and subtherapeutic concentrations. International Journal of Antimicrobial Agents, 46 (1), 21-27. doi: 10.1016/j.ijantimicag.2015.02.009
2015
Journal Article
Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Peake, Sandra L. and Roberts, Jason A. (2015). Influence of sustained low-efficiency diafiltration (SLED-f) on interstitial fluid concentrations of fluconazole in a critically ill patient: use of microdialysis. International Journal of Antimicrobial Agents, 46 (1), 121-124. doi: 10.1016/j.ijantimicag.2015.02.017
2015
Journal Article
Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration
Jamal, Janattul-Ain, Roberts, Darren M., Udy, Andrew A., Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of piperacillin in critically ill patients receiving continuous venovenous haemofiltration: a randomised controll edtrial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 46 (1), 39-44. doi: 10.1016/j.ijantimicag.2015.02.014
2015
Journal Article
Pharmacokinetics and preliminary safety ofhigh dose linezolid for the treatment of Gram-positive bacterial infections
Lopez-Garcia, Belen, Luque, Sonia, Roberts, Jason A. and Grau, Santiago (2015). Pharmacokinetics and preliminary safety ofhigh dose linezolid for the treatment of Gram-positive bacterial infections. Journal of Infection, 71 (5), 604-607. doi: 10.1016/j.jinf.2015.06.007
2015
Journal Article
Microbiologic clearance following transition from standard infusion piperacillin-tazobactam to extended-infusion for persistent Gram-negative bacteremia and possible endocarditis: a case report and review of the literature
D'Agostino, Carly, Rhodes, Nathaniel J., Skoglund, Erik, Roberts, Jason A. and Scheetz, Marc H. (2015). Microbiologic clearance following transition from standard infusion piperacillin-tazobactam to extended-infusion for persistent Gram-negative bacteremia and possible endocarditis: a case report and review of the literature. Journal of Infection and Chemotherapy, 21 (10), 742-746. doi: 10.1016/j.jiac.2015.05.010
2015
Journal Article
Australian National Enterovirus Reference Laboratory annual report, 2013
Roberts, Jason A., Hobday, Linda K., Ibrahim, Aishah, Aitkin, Thomas and Thorley, Bruce R. (2015). Australian National Enterovirus Reference Laboratory annual report, 2013. Communicable Diseases Intelligence Quarterly Report, 39 (2), E208-E216.
2015
Journal Article
Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis
Brink, A. J., Richards, G. A., Lautenbach, E. E. G., Rapeport, N., Schillack, V., van Niekerk, L., Lipman, J. and Roberts, J. A. (2015). Albumin concentration significantly impacts on free teicoplanin plasma concentrations in non-critically ill patients with chronic bone sepsis. International Journal of Antimicrobial Agents, 45 (6), 647-651. doi: 10.1016/j.ijantimicag.2015.01.015
2015
Journal Article
Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial
Sime, Fekade B., Roberts, Michael S., Tiong, Ing S., Gardner, Julia H., Lehman, Sheila, Peake, Sandra L., Hahn, Uwe, Warner, Morgyn S. and Roberts, Jason A. (2015). Can therapeutic drug monitoring optimize exposure to piperacillin in febrile neutropenic patients with haematological malignancies? A randomized controlled trial. Journal of Antimicrobial Chemotherapy, 70 (8) dkv123, 2369-2375. doi: 10.1093/jac/dkv123
2015
Journal Article
Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply
Hanrahan, Timothy P., Harlow, Georgina, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2015). Vancomycin-associated nephrotoxicity: unintentional consequences of a loading dose? Reply. Critical Care Medicine, 43 (5), E154-E155. doi: 10.1097/CCM.0000000000000952
2015
Journal Article
How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?
Jamal, Janattul-Ain, Mueller, Bruce A., Choi, Gordon Y. S., Lipman, Jeffrey and Roberts, Jason A. (2015). How can we ensure effective antibiotic dosing in critically ill patients receiving different types of renal replacement therapy?. Diagnostic Microbiology and Infectious Disease, 82 (1), 92-103. doi: 10.1016/j.diagmicrobio.2015.01.013
2015
Journal Article
Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients
De Waele, J. J., Lipman, J., Akova, M., Bassetti, M. , Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P. , Rello, J. , Rhodes, A. , Udy, A. A. , Starr, T. , Wallis, S. C. and Roberts, J. A. (2015). Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 41 (5), 969-969. doi: 10.1007/s00134-015-3772-7
2015
Journal Article
Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study
Shekar, Kiran, Roberts, Jason A, Mcdonald, Charles I, Ghassabian, Sussan, Anstey, Chris, Wallis, Steven C, Mullany, Daniel V, Fung, Yoke L and Fraser, John F (2015). Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: Results from an ex vivo study. Critical Care, 19 (164) 164, 164. doi: 10.1186/s13054-015-0891-z
2015
Journal Article
A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics
Roberts, Darren M, Liu, Xin, Roberts, Jason A, Nair, Priya, Cole, Louise, Roberts, Michael S, Lipman, Jeffrey, Bellomo, Rinaldo and RENAL Replacement Therapy Study Investigators (2015). A multicenter study on the effect of continuous hemodiafiltration intensity on antibiotic pharmacokinetics. Critical Care, 19 (84) 84, 84. doi: 10.1186/s13054-015-0818-8
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jason Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Pharmacokinetics of anti-mycobacterial drugs in patients with cystic fibrosis
Principal Advisor
Other advisors: Professor Rachel Thomson, Professor Scott Bell
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Principal Advisor
Other advisors: Dr Mark Coulthard, Professor Jeffrey Lipman, Dr Xin Liu, Dr Patty Mitre
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
What is the validity of altered dosing approaches for ensuring appropriate antibiotic dosing in the critically ill?
Principal Advisor
-
Doctor Philosophy
Suitability of ß-lactam and ß-lactamase inhibitor combinations for use in outpatient parenteral antimicrobial therapy
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Precision antimicrobial dosing in infected critically ill patients
Principal Advisor
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Honorary Professor Luregn Schlapbach
-
Doctor Philosophy
Improving drug therapy for children with sepsis and life-threatening infections
Principal Advisor
Other advisors: Honorary Professor Luregn Schlapbach, Dr Sainath Raman
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Designing and Implementing a Clinician-Led Protocol for Heparinisation Using Optimal Targets- anti Xa vs APTT
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimising the stability and dosing regimens of antibiotics for outpatient parenteral antibiotic therapy
Associate Advisor
Other advisors: Dr Fekade Sime
-
Master Philosophy
Designing and implementing a nurse-led electronic medical record (EMR) integrated heparinisation protocol using optimal targets (anti Xa vs APTT)
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimising antibiotic dosing for the treatment and prevention of central nervous system infections
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
Doctor Philosophy
In vitro evaluation of the impact of different durations of exposure of fast-acting antimicrobials in combination with beta-lactams
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients.
Associate Advisor
Other advisors: Professor Victoria Eley
Completed supervision
-
2025
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Dr Fekade Sime
-
2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Dr Hafiz Abdul-Aziz
-
2022
Doctor Philosophy
Microbiological evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum ß-lactamase-producing Escherichia coli
Principal Advisor
Other advisors: Dr Fekade Sime
-
2022
Doctor Philosophy
Evaluation of combination antibiotic regimens for the treatment of multidrug-resistant Acinetobacter baumannii infections
Principal Advisor
Other advisors: Dr Fekade Sime
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Principal Advisor
Other advisors: Professor Kiran Shekar, Dr Hafiz Abdul-Aziz
-
2020
Doctor Philosophy
Optimisation of alternative antibiotic dosing regimens for maximal antibacterial activity and suppression of emergence of resistance
Principal Advisor
Other advisors: Dr Fekade Sime
-
2019
Doctor Philosophy
A pharmacokinetic/pharmacodynamic and clinical outcome evaluation of beta-lactam antibiotic therapeutic drug monitoring in critically ill patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2019
Doctor Philosophy
Study of the disposition of nebulized tobramycin
Principal Advisor
Other advisors: Professor John Fraser, Associate Professor Jeremy Cohen
-
2017
Doctor Philosophy
Improving antibiotic dosing in critically ill Australian Indigenous patients with severe sepsis
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Translating Innovative Pharmacokinetic Sampling Techniques into Improved Antibiotic Dosing Regimens in Critically Ill Patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Dr Christine Staatz, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
ß-lactam antibiotic pharmacokinetics during continuous venovenous haemofiltration in critically ill patients: Continuous infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2015
Master Philosophy
Vancomycin-associated nephrotoxicity in the Critically-Ill
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2024
Doctor Philosophy
Optimising Antibiotic Dosing for Treatment of Nosocomial Central Nervous System Infections in Neurocritical Care Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
Personalising Antimicrobial Therapy in Critically Ill Patients using Bayesian Dosing Software
Associate Advisor
-
2023
Doctor Philosophy
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Associate Advisor
Other advisors: Professor Peter Cabot, Professor Amirali Popat, Dr Fekade Sime, Dr James Robert Falconer
-
2017
Master Philosophy
Improving the quality of prescribing in elderly hospital inpatients: evaluating the effect of a clinical pharmacist on ward rounds
Associate Advisor
-
2016
Doctor Philosophy
Sick Patients, Starved Circuits and Sticky Drugs: Understanding pharmacokinetics during extracorporeal membrane oxygenation to optimise drug dosing and improve patient outcomes
Associate Advisor
Other advisors: Professor John Fraser
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman, Emeritus Professor Michael Roberts
-
2014
Doctor Philosophy
Dose optimisation of antibiotics during different forms of renal replacement therapy: focus on tissue and target site antibiotic concentrations
Associate Advisor
Other advisors: Associate Professor Robert Boots, Professor Jeffrey Lipman
-
2014
Doctor Philosophy
Improving Antimicrobial Use In Critically Ill Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2012
Master Philosophy
Challenges in management of infections on a burn injury unit.
Associate Advisor
Other advisors: Professor Jeffrey Lipman
Media
Enquiries
Contact Professor Jason Roberts directly for media enquiries about:
- Antibiotics
- Drug dosage
- Therapeutic drug monitoring
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