
Overview
Background
Professor Jason Roberts is Director of the University of Queensland Centre for Clinical Research (UQCCR), an Australian National Health and Medical Research Council (NHMRC) Leadership Fellow L2 at The University of Queensland. He is also a Consultant Clinical Pharmacist at the Royal Brisbane and Women’s Hospital and Interim Director of the Herston Infectious Diseases Institute (HeIDI). He is Director of the NHMRC-funded Centre for Research Excellence RESPOND which is based at UQCCR. He is a clinician-scientist with a strong interest in research and his principal research theme is optimization of antimicrobial dosing in the critically ill. Prof Roberts has authored over 650 published papers and book chapters on this topic, has been awarded over $55 million in grants and has supervised >20 PhD students to completion.
Prof Roberts was recognised as Australia’s leading researcher in two separate categories, Critical Care and Communicable Diseases, by the Australian’s 2019 Research Magazine.
He has been invited to present his results at major international conferences in critical care, infectious diseases, pharmacy, nephrology, transplant and safety. He has served on the Critical Review Panel for ATS/IDSA Guidelines of HAP, HCAP and VAP and the Australian Therapeutic Guidelines - Antibiotic and the 2021 Surviving Sepsis Guidelines. He is the Past Chair of the Working Group for Antimicrobial Use in ICU for the European Society of Intensive Care Medicine and an Executive Member of the PK/PD Group (EPASG) within the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).
He is Section Editor for the International Journal of Antimicrobial Agents and an Associate Editor of the Journal or Pharmacy Practice and Research, the journal for the Society of Hospital Pharmacists of Australia and an Associate Editor for Pharmacotherapy and Aanesthesiology Pain and Critical Care Medicine journal. He has convened >50 seminars/conferences including being co-convenor for Medicines Management 2013, The National Conference for Society of Hospital Pharmacists of Australia.
He also engages with Industry to perform studies that develop optimised antibiotic dosing regimens that maximise antibiotic efficacy for testing in clinical trials or for use in special patient populations (e.g. critically ill, pneumonia, dialysis).
Availability
- Professor Jason Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours), University of Sydney
- Doctor of Philosophy, The University of Queensland
- Society of Hospital Pharmacists of Australia, Society of Hospital Pharmacists of Australia
Works
Search Professor Jason Roberts’s works on UQ eSpace
2014
Journal Article
Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies
Sime, Fekade Bruck, Roberts, Michael S., Roberts, Jason A. and Robertson, Thomas A. (2014). Simultaneous determination of seven β-lactam antibiotics in human plasma for therapeutic drug monitoring and pharmacokinetic studies. Journal of Chromatography B, 960, 134-144. doi: 10.1016/j.jchromb.2014.04.029
2014
Journal Article
Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration
Maseda, Emilio, Grau, Santiago, Villagran, Maria-Jose, Hernandez-Gancedo, Carmen, Lopez-Tofino, Araceli, Roberts, Jason A., Aguilar, Lorenzo, Luque, Sonia, Sevillano, David, Gimenez, Maria-Jose and Gilsanz, Fernando (2014). Micafungin pharmacokinetic/pharmacodynamic adequacy for the treatment of invasive candidiasis in critically ill patients on continuous venovenous haemofiltration. Journal of Antimicrobial Chemotherapy, 69 (6), 1624-1632. doi: 10.1093/jac/dku013
2014
Journal Article
Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?
Nunez-Nunez, Maria, Bellapart, Judith, O’Donoghue, Steven, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Variable ganciclovir concentrations in a critically ill patient receiving continuous renal replacement therapy and plasma exchange?. International journal of antimicrobial agents, 43 (6), 572-573. doi: 10.1016/j.ijantimicag.2014.03.001
2014
Journal Article
Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study
Blot, Stijn, Koulenti, Despoina, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2014). Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study. Critical Care, 18 (3) R99, 1-11. doi: 10.1186/cc13874
2014
Journal Article
Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients
Roberts, Jason A., Udy, Andrew A., Jarrett, Paul, Wallis, Steven C., Hope, William W., Sharma, Raman, Kirkpatrick, Carl M. J., Kruger, Peter S., Roberts, Michael S. and Lipman, Jeffrey (2014). Plasma and target-site subcutaneous tissue population pharmacokinetics and dosing simulations of cefazolin in post-trauma critically ill patients. Journal of Antimicrobial Chemotherapy, 70 (5) dku564, 1495-1502. doi: 10.1093/jac/dku564
2014
Journal Article
An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units
Wong, Gloria, Brinkman, Alexander, Benefield, Russell J., Carlier, Mieke, De Waele, Jan J., Helali, Najoua, Frey, Otto, Harbarth, Stephan, Huttner, Angela, McWhinney, Brett, Misset, Benoit, Pea, Federico, Preisenberger, Judit, Roberts, Michael S., Robertson, Thomas A., Roehr, Anka, Sime, Fekade Bruck, Taccone, Fabio Silvio, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). An international, multicentre survey of β-lactam antibiotic therapeutic drug monitoring practice in intensive care units. Journal of Antimicrobial Chemotherapy, 69 (5) dkt523, 1416-1423. doi: 10.1093/jac/dkt523
2014
Journal Article
The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?
Blot,Stijn, Lipman, Jeffrey, Roberts, Darren M. and Roberts, Jason A (2014). The influence of acute kidney injury on antimicrobial dosing in critically ill patients: Are dose reductions always necessary?. Diagnostic Microbiology and Infectious Disease, 79 (1), 77-84. doi: 10.1016/j.diagmicrobio.2014.01.015
2014
Journal Article
DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?
Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). DALI: defining antibiotic levels in intensive care unit patients. Are current beta-lactam antibiotic doses sufficient for critically ill patients?. Clinical Infectious Diseases, 58 (8), 1072-1083. doi: 10.1093/cid/ciu027
2014
Journal Article
Cefazolin plasma protein binding in different human populations: More than cefazolin-albumin interaction
Smits, Anne, Roberts, Jason A., Vella-Brincat, Jane W. A. and Allegaert, Karel (2014). Cefazolin plasma protein binding in different human populations: More than cefazolin-albumin interaction. International Journal of Antimicrobial Agents, 43 (2), 199-200. doi: 10.1016/j.ijantimicag.2013.10.008
2014
Journal Article
Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration
Roberts, Jason A., Udy, Andrew A., Bulitta, Juergen B., Stuart, Janin, Jarrett, Paul, Starr, Therese, Lassig-Smith, Melissa, Roberts, Natasha A., Dunlop, Rachel, Hayashi, Yoshiro, Wallis, Steven C. and Lipman, Jeffrey (2014). Doripenem population pharmacokinetics and dosing requirements for critically ill patients receiving continuous venovenous haemodiafiltration. Journal of Antimicrobial Chemotherapy, 69 (9) dku177, 2508-2516. doi: 10.1093/jac/dku177
2014
Journal Article
Antibiotic dosing in critically ill patients with septic shock and on continuous renal replacement therapy: can we resolve this problem with pharmacokinetic studies and dosing guidelines?
Roberts, Jason A. and Roberts, Darren M. (2014). Antibiotic dosing in critically ill patients with septic shock and on continuous renal replacement therapy: can we resolve this problem with pharmacokinetic studies and dosing guidelines?. Critical Care, 18 (3) 156. doi: 10.1186/cc13939
2014
Journal Article
Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study
Roberts, J. A., Stove, V., De Waele, J. J., Sipinkoski, B., McWhinney, B., Ungerer, J. P. J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, K.-M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Starr, T., Wallis, S. C. and Lipman, J. (2014). Variability in protein binding of teicoplanin and achievement of therapeutic drug monitoring targets in critically ill patients: Lessons from the DALI Study. International Journal of Antimicrobial Agents, 43 (5), 423-430. doi: 10.1016/j.ijantimicag.2014.01.023
2014
Journal Article
A national survey of renal replacement therapy prescribing practice for acute kidney injury in Malaysian intensive care units
Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). A national survey of renal replacement therapy prescribing practice for acute kidney injury in Malaysian intensive care units. Nephrology, 19 (8), 507-512. doi: 10.1111/nep.12276
2014
Journal Article
Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions
Roberts, Jason A., Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Vinks, Alexander ., Felton, Timothy W., Hope, William W., Farkas, Andras, Neely, Michael N., Schentag, Jerome J., Drusano, George, Frey, Otto R., Theuretzbacher, Ursula and Kuti, Joseph L. (2014). Individualised antibiotic dosing for patients who are critically ill: Challenges and potential solutions. The Lancet Infectious Diseases, 14 (6), 498-509. doi: 10.1016/S1473-3099(14)70036-2
2014
Journal Article
Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients
De Waele, Jan J., Lipman, J., Akova, M., Bassetti, M., Dimopoulos, G., Kaukonen, M., Koulenti, D., Martin, C., Montravers, P., Rello, J., Rhodes, A., Udy, A. A., Starr, T., Wallis, S. C. and Roberts, J. A. (2014). Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients. Intensive Care Medicine, 40 (9), 1340-1351. doi: 10.1007/s00134-014-3403-8
2014
Journal Article
Antimicrobial stewardship activities: a survey of Queensland hospitals
Avent, Minyon L., Hall, Lisa, Davis, Louise, Allen, Michelle, Roberts, Jason A., Unwin, Sean, McIntosh, Kylie A., Thursky, Karin, Buising, Kirsty and Paterson, David L. (2014). Antimicrobial stewardship activities: a survey of Queensland hospitals. Australian Health Review, 38 (5), 557-563. doi: 10.1071/AH13137
2014
Journal Article
Preface
Holstege, Gert, Beers, Caroline M. and Subramanian, Hari H. (2014). Preface. Progress in Brain Research, 209, xi-xii. doi: 10.1016/B978-0-444-63488-7.10000-X
2014
Conference Publication
The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units
Tabah, A., Roberts, J., De Waele, J. J., Lipman, J., Zahar, J. R., Cotta, M. O., Barton, G. and Timsit, J. -F. (2014). The ADMIN-ICU survey: A survey on antimicrobials dosing and monitoring strategies in intensive care units. 27th Annual Congress of the European Society of Intensive Care Medicine (ESICM), Barcelona, Spain, 27 September-1 October 2014. Heidelberg, Germany: Springer. doi: 10.1007/s00134-014-3451-0
2014
Conference Publication
Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis
Abdul-Aziz, M., Udy, A., Wallis, S., Roberts, M., Lipman, J. and Roberts, J. (2014). Plasma and subcutaneous tissue pharmacokinetics of piperacillin in a large cohort of critically ill patients with sepsis. European Congress of Clinical Microbiology & Infectious Diseases, Barcelona, Spain, 10-13 May 2014.
2014
Journal Article
Antimicrobial stewardship of β-lactams in intensive care units
Cotta, Menino Osbert, Roberts, Jason A., Tabah, Alexis, Lipman, Jeffrey, Vogelaers, Dirk and Blot, Stijn (2014). Antimicrobial stewardship of β-lactams in intensive care units. Expert Review of Anti-Infective Therapy, 12 (5), 581-595. doi: 10.1586/14787210.2014.902308
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jason Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Suitability of ß-lactam and ß-lactamase inhibitor combinations for use in outpatient parenteral antimicrobial therapy
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Principal Advisor
Other advisors: Dr Mark Coulthard, Professor Jeffrey Lipman, Dr Xin Liu, Dr Patty Mitre
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Honorary Professor Luregn Schlapbach
-
Doctor Philosophy
Precision antimicrobial dosing in infected critically ill patients
Principal Advisor
-
Doctor Philosophy
Improving drug therapy for children with sepsis and life-threatening infections
Principal Advisor
Other advisors: Honorary Professor Luregn Schlapbach, Dr Sainath Raman
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Pharmacokinetics of anti-mycobacterial drugs in patients with cystic fibrosis
Principal Advisor
Other advisors: Professor Rachel Thomson, Professor Scott Bell
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
What is the validity of altered dosing approaches for ensuring appropriate antibiotic dosing in the critically ill?
Principal Advisor
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
Optimising antibiotic dosing for the treatment and prevention of central nervous system infections
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients.
Associate Advisor
Other advisors: Professor Victoria Eley
-
Doctor Philosophy
Designing and Implementing a Clinician-Led Protocol for Heparinisation Using Optimal Targets- anti Xa vs APTT
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimising the stability and dosing regimens of antibiotics for outpatient parenteral antibiotic therapy
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
In vitro evaluation of the impact of different durations of exposure of fast-acting antimicrobials in combination with beta-lactams
Associate Advisor
Other advisors: Dr Fekade Sime
-
Master Philosophy
Designing and implementing a nurse-led electronic medical record (EMR) integrated heparinisation protocol using optimal targets (anti Xa vs APTT)
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
Completed supervision
-
2025
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Dr Fekade Sime
-
2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Dr Hafiz Abdul-Aziz
-
2022
Doctor Philosophy
Microbiological evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum ß-lactamase-producing Escherichia coli
Principal Advisor
Other advisors: Dr Fekade Sime
-
2022
Doctor Philosophy
Evaluation of combination antibiotic regimens for the treatment of multidrug-resistant Acinetobacter baumannii infections
Principal Advisor
Other advisors: Dr Fekade Sime
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Principal Advisor
Other advisors: Professor Kiran Shekar, Dr Hafiz Abdul-Aziz
-
2020
Doctor Philosophy
Optimisation of alternative antibiotic dosing regimens for maximal antibacterial activity and suppression of emergence of resistance
Principal Advisor
Other advisors: Dr Fekade Sime
-
2019
Doctor Philosophy
A pharmacokinetic/pharmacodynamic and clinical outcome evaluation of beta-lactam antibiotic therapeutic drug monitoring in critically ill patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2019
Doctor Philosophy
Study of the disposition of nebulized tobramycin
Principal Advisor
Other advisors: Professor John Fraser, Associate Professor Jeremy Cohen
-
2017
Doctor Philosophy
Improving antibiotic dosing in critically ill Australian Indigenous patients with severe sepsis
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Translating Innovative Pharmacokinetic Sampling Techniques into Improved Antibiotic Dosing Regimens in Critically Ill Patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Dr Christine Staatz, Professor Jeffrey Lipman
-
2015
Master Philosophy
Vancomycin-associated nephrotoxicity in the Critically-Ill
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2015
Doctor Philosophy
ß-lactam antibiotic pharmacokinetics during continuous venovenous haemofiltration in critically ill patients: Continuous infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2024
Doctor Philosophy
Optimising Antibiotic Dosing for Treatment of Nosocomial Central Nervous System Infections in Neurocritical Care Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
Personalising Antimicrobial Therapy in Critically Ill Patients using Bayesian Dosing Software
Associate Advisor
-
2023
Doctor Philosophy
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Associate Advisor
Other advisors: Professor Peter Cabot, Professor Amirali Popat, Dr Fekade Sime, Dr James Robert Falconer
-
2017
Master Philosophy
Improving the quality of prescribing in elderly hospital inpatients: evaluating the effect of a clinical pharmacist on ward rounds
Associate Advisor
-
2016
Doctor Philosophy
Sick Patients, Starved Circuits and Sticky Drugs: Understanding pharmacokinetics during extracorporeal membrane oxygenation to optimise drug dosing and improve patient outcomes
Associate Advisor
Other advisors: Professor John Fraser
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman, Emeritus Professor Michael Roberts
-
2014
Doctor Philosophy
Dose optimisation of antibiotics during different forms of renal replacement therapy: focus on tissue and target site antibiotic concentrations
Associate Advisor
Other advisors: Associate Professor Robert Boots, Professor Jeffrey Lipman
-
2014
Doctor Philosophy
Improving Antimicrobial Use In Critically Ill Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2012
Master Philosophy
Challenges in management of infections on a burn injury unit.
Associate Advisor
Other advisors: Professor Jeffrey Lipman
Media
Enquiries
Contact Professor Jason Roberts directly for media enquiries about:
- Antibiotics
- Drug dosage
- Therapeutic drug monitoring
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