
Overview
Background
Professor Jason Roberts is Director of the University of Queensland Centre for Clinical Research (UQCCR), an Australian National Health and Medical Research Council (NHMRC) Leadership Fellow L2 at The University of Queensland. He is also a Consultant Clinical Pharmacist at the Royal Brisbane and Women’s Hospital and Interim Director of the Herston Infectious Diseases Institute (HeIDI). He is Director of the NHMRC-funded Centre for Research Excellence RESPOND which is based at UQCCR. He is a clinician-scientist with a strong interest in research and his principal research theme is optimization of antimicrobial dosing in the critically ill. Prof Roberts has authored over 650 published papers and book chapters on this topic, has been awarded over $55 million in grants and has supervised >20 PhD students to completion.
Prof Roberts was recognised as Australia’s leading researcher in two separate categories, Critical Care and Communicable Diseases, by the Australian’s 2019 Research Magazine.
He has been invited to present his results at major international conferences in critical care, infectious diseases, pharmacy, nephrology, transplant and safety. He has served on the Critical Review Panel for ATS/IDSA Guidelines of HAP, HCAP and VAP and the Australian Therapeutic Guidelines - Antibiotic and the 2021 Surviving Sepsis Guidelines. He is the Past Chair of the Working Group for Antimicrobial Use in ICU for the European Society of Intensive Care Medicine and an Executive Member of the PK/PD Group (EPASG) within the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).
He is Section Editor for the International Journal of Antimicrobial Agents and an Associate Editor of the Journal or Pharmacy Practice and Research, the journal for the Society of Hospital Pharmacists of Australia and an Associate Editor for Pharmacotherapy and Aanesthesiology Pain and Critical Care Medicine journal. He has convened >50 seminars/conferences including being co-convenor for Medicines Management 2013, The National Conference for Society of Hospital Pharmacists of Australia.
He also engages with Industry to perform studies that develop optimised antibiotic dosing regimens that maximise antibiotic efficacy for testing in clinical trials or for use in special patient populations (e.g. critically ill, pneumonia, dialysis).
Availability
- Professor Jason Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours), University of Sydney
- Doctor of Philosophy, The University of Queensland
- Society of Hospital Pharmacists of Australia, Society of Hospital Pharmacists of Australia
Works
Search Professor Jason Roberts’s works on UQ eSpace
2014
Journal Article
Risk factors in hospitalized patients with burn injuries for developing heterotopic ossification—a retrospective analysis
Orchard, Gregory R., Paratz, Jennifer D., Blot, Stijn and Roberts, Jason A. (2014). Risk factors in hospitalized patients with burn injuries for developing heterotopic ossification—a retrospective analysis. Journal of Burn Care and Research, 36 (4), 465-470. doi: 10.1097/BCR.0000000000000123
2014
Journal Article
The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study
Shekar, Kiran, Fraser, John F., Taccone, Fabio Silvio, Welch, Susan, Wallis, Steven C., Mullany, Daniel V., Lipman, Jeffrey and Roberts, Jason A. (2014). The combined effects of extracorporeal membrane oxygenation and renal replacement therapy on meropenem pharmacokinetics: a matched cohort study. Critical Care, 18 (6) 565, 1-9. doi: 10.1186/s13054-014-0565-2
2014
Journal Article
Decreasing the time to achieve therapeutic vancomycin concentrations in critically ill patients: Developing and testing of a dosing nomogram
Baptista, Joao P., Roberts, Jason A., Sousa, Eduardo, Freitas, Ricardo, Deveza, Nuno and Pimentel, Jorge (2014). Decreasing the time to achieve therapeutic vancomycin concentrations in critically ill patients: Developing and testing of a dosing nomogram. Critical Care, 18 (654) 654, 1-9. doi: 10.1186/s13054-014-0654-2
2014
Journal Article
Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis
De Waele, J., Carlier, M., Hoste, E., Depuydt, P., Decruyenaere, J., Wallis, S. C., Lipman, J. and Roberts, J. A. (2014). Extended versus bolus infusion of meropenem and piperacillin: a pharmacolcinetic analysis. Minerva Anestesiologica, 80 (12), 1302-1309.
2014
Journal Article
Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014
Chau, M. M., Kong, D. C. M., van Hal, S. J., Urbancic, K., Trubiano, J. A., Cassumbhoy, M., Wilkes, J., Cooper, C. M., Roberts, J. A., Marriott, D. J. E. and Worth, L. J. (2014). Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014. Internal Medicine Journal, 44 (12), 1364-1388. doi: 10.1111/imj.12600
2014
Journal Article
Therapeutic drug monitoring of antibiotics – author's reply
Roberts, Jason A. (2014). Therapeutic drug monitoring of antibiotics – author's reply. Lancet Infectious Diseases, 14 (12), 1181-1181. doi: 10.1016/S1473-3099(14)71007-2
2014
Journal Article
Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis
Hanrahan, Timothy P., Harlow, Georgina, Hutchinson, James, Dulhunty, Joel M., Lipman, Jeffrey, Whitehouse, Tony and Roberts, Jason A. (2014). Vancomycin-associated nephrotoxicity in the critically ill: a retrospective multivariate regression analysis. Critical Care Medicine, 42 (12), 2527-2536. doi: 10.1097/CCM.0000000000000514
2014
Journal Article
Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds
Udy, Andrew A., Jarrett, Paul, Stuart, Janine, Lassig-Smith, Melissa, Starr, Therese, Dunlop, Rachel, Wallis, Steven C., Roberts, Jason A. and Lipman, Jeffrey (2014). Determining the mechanisms underlying augmented renal drug clearance in the critically ill: use of exogenous marker compounds. Critical Care, 18 (657) 657, 1-9. doi: 10.1186/s13054-014-0657-z
2014
Journal Article
How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?
Wong, Gloria, Sime, Fekade Bruck, Lipman, Jeffrey and Roberts, Jason A. (2014). How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?. BMC Infectious Diseases, 14 (288) 288, 1-11. doi: 10.1186/1471-2334-14-288
2014
Journal Article
Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study
Donadello, Katia, Roberts, Jason A., Cristallini, Stefano, Beumier, Marjorie, Shekar, Kiran, Jacobs, Frederique, Belhaj, Asmae, Vincent, Jean-Louis, de Backer, Daniel and Taccone, Fabio Silvio (2014). Vancomycin population pharmacokinetics during extracorporeal membrane oxygenation therapy: a matched cohort study. Critical Care, 18 (632) 632, 1-10. doi: 10.1186/s13054-014-0632-8
2014
Journal Article
Interethnic differences in pharmacokinetics of antibacterials
Tsai, Danny, Jamal, Janattul-Ain, Davis, Joshua S., Lipman, Jeffrey and Roberts, Jason A. (2014). Interethnic differences in pharmacokinetics of antibacterials. Clinical Pharmacokinetics, 54 (3), 243-260. doi: 10.1007/s40262-014-0209-3
2014
Journal Article
Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit
Adnan, S., Ratnam, S., Kumar, S., Paterson, D., Lipman, J., Roberts, J. and Udy, A. A. (2014). Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit. Anaesthesia And Intensive Care, 42 (6), 715-722. doi: 10.1177/0310057X1404200606
2014
Journal Article
Meeting the challenges of advanced drug delivery in critical illness
Roberts, Jason A. and Fraser, John F. (2014). Meeting the challenges of advanced drug delivery in critical illness. Advanced Drug Delivery Reviews, 77, 1-2. doi: 10.1016/j.addr.2014.11.002
2014
Journal Article
Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures
Carlier, Mieke, Noe, Michael, Roberts, Jason A., Stove, Veronique, Verstraete, Alain G., Lipman, Jeffrey and De Waele, Jan J. (2014). Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures. Journal of Antimicrobial Chemotherapy, 69 (10), 2797-2803. doi: 10.1093/jac/dku195
2014
Journal Article
Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU
Abdul-Aziz, Mohd H., McDonald, Craig, McWhinney, Brett, Ungerer, Jacobus P. J., Lipman, Jeffrey and Roberts, Jason A. (2014). Low flucloxacillin concentrations in a patient with central nervous system infection: the need for plasma and cerebrospinal fluid drug monitoring in the ICU. Annals of Pharmacotherapy, 48 (10), 1380-1384. doi: 10.1177/1060028014540610
2014
Journal Article
Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al
Roberts, Jason A., Paul, Sanjoy K., Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Dimopoulos, George, Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Lipman, Jeffrey (2014). Impact of loading doses on the time to adequate predicted beta-lactam concentrations in prolonged and continuous infusion dosing schemes: reply to Rhodes et al. Clinical Infectious Diseases, 59 (6), 907-908. doi: 10.1093/cid/ciu403
2014
Journal Article
Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections
Luque, S., Grau, S., Alvarez-Lerma, F., Ferrandez, O., Campillo, N., Horcajada, J.P., Basas, M., Lipman, J. and Roberts, J.A. (2014). Plasma and cerebrospinal fluid concentrations of linezolid in neurosurgical critically ill patients with proven or suspected central nervous system infections. International Journal of Antimicrobial Agents, 44 (5), 409-415. doi: 10.1016/j.ijantimicag.2014.07.001
2014
Journal Article
How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?
Felton, T. W., Hope, W. W. and Roberts, J. A. (2014). How severe is antibiotic pharmacokinetic variability in critically ill patients and what can be done about it?. Diagnostic Microbiology and Infectious Disease, 79 (4), 441-447. doi: 10.1016/j.diagmicrobio.2014.04.007
2014
Journal Article
The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens
Jamal, Janattul-Ain, Udy, Andrew A., Lipman, Jeffrey and Roberts, Jason A. (2014). The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens. Critical Care Medicine, 42 (7), 1640-1650. doi: 10.1097/CCM.0000000000000317
2014
Journal Article
Amikacin dosing in the ICU: we now know more, but still not enough ...
De Rosa, Francesco G. and Roberts, Jason A. (2014). Amikacin dosing in the ICU: we now know more, but still not enough .... Intensive Care Medicine, 40 (7), 1033-1035. doi: 10.1007/s00134-014-3308-6
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jason Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Pharmacokinetics of anti-mycobacterial drugs in patients with cystic fibrosis
Principal Advisor
Other advisors: Professor Rachel Thomson, Professor Scott Bell
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Principal Advisor
Other advisors: Dr Mark Coulthard, Professor Jeffrey Lipman, Dr Xin Liu, Dr Patty Mitre
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
What is the validity of altered dosing approaches for ensuring appropriate antibiotic dosing in the critically ill?
Principal Advisor
-
Doctor Philosophy
Suitability of ß-lactam and ß-lactamase inhibitor combinations for use in outpatient parenteral antimicrobial therapy
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Precision antimicrobial dosing in infected critically ill patients
Principal Advisor
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Honorary Professor Luregn Schlapbach
-
Doctor Philosophy
Improving drug therapy for children with sepsis and life-threatening infections
Principal Advisor
Other advisors: Honorary Professor Luregn Schlapbach, Dr Sainath Raman
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Designing and Implementing a Clinician-Led Protocol for Heparinisation Using Optimal Targets- anti Xa vs APTT
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimising the stability and dosing regimens of antibiotics for outpatient parenteral antibiotic therapy
Associate Advisor
Other advisors: Dr Fekade Sime
-
Master Philosophy
Designing and implementing a nurse-led electronic medical record (EMR) integrated heparinisation protocol using optimal targets (anti Xa vs APTT)
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimising antibiotic dosing for the treatment and prevention of central nervous system infections
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
Doctor Philosophy
In vitro evaluation of the impact of different durations of exposure of fast-acting antimicrobials in combination with beta-lactams
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients.
Associate Advisor
Other advisors: Professor Victoria Eley
Completed supervision
-
2025
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Dr Fekade Sime
-
2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Dr Hafiz Abdul-Aziz
-
2022
Doctor Philosophy
Microbiological evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum ß-lactamase-producing Escherichia coli
Principal Advisor
Other advisors: Dr Fekade Sime
-
2022
Doctor Philosophy
Evaluation of combination antibiotic regimens for the treatment of multidrug-resistant Acinetobacter baumannii infections
Principal Advisor
Other advisors: Dr Fekade Sime
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Principal Advisor
Other advisors: Professor Kiran Shekar, Dr Hafiz Abdul-Aziz
-
2020
Doctor Philosophy
Optimisation of alternative antibiotic dosing regimens for maximal antibacterial activity and suppression of emergence of resistance
Principal Advisor
Other advisors: Dr Fekade Sime
-
2019
Doctor Philosophy
A pharmacokinetic/pharmacodynamic and clinical outcome evaluation of beta-lactam antibiotic therapeutic drug monitoring in critically ill patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2019
Doctor Philosophy
Study of the disposition of nebulized tobramycin
Principal Advisor
Other advisors: Professor John Fraser, Associate Professor Jeremy Cohen
-
2017
Doctor Philosophy
Improving antibiotic dosing in critically ill Australian Indigenous patients with severe sepsis
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Translating Innovative Pharmacokinetic Sampling Techniques into Improved Antibiotic Dosing Regimens in Critically Ill Patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Dr Christine Staatz, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
ß-lactam antibiotic pharmacokinetics during continuous venovenous haemofiltration in critically ill patients: Continuous infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2015
Master Philosophy
Vancomycin-associated nephrotoxicity in the Critically-Ill
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2024
Doctor Philosophy
Optimising Antibiotic Dosing for Treatment of Nosocomial Central Nervous System Infections in Neurocritical Care Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
Personalising Antimicrobial Therapy in Critically Ill Patients using Bayesian Dosing Software
Associate Advisor
-
2023
Doctor Philosophy
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Associate Advisor
Other advisors: Professor Peter Cabot, Professor Amirali Popat, Dr Fekade Sime, Dr James Robert Falconer
-
2017
Master Philosophy
Improving the quality of prescribing in elderly hospital inpatients: evaluating the effect of a clinical pharmacist on ward rounds
Associate Advisor
-
2016
Doctor Philosophy
Sick Patients, Starved Circuits and Sticky Drugs: Understanding pharmacokinetics during extracorporeal membrane oxygenation to optimise drug dosing and improve patient outcomes
Associate Advisor
Other advisors: Professor John Fraser
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman, Emeritus Professor Michael Roberts
-
2014
Doctor Philosophy
Dose optimisation of antibiotics during different forms of renal replacement therapy: focus on tissue and target site antibiotic concentrations
Associate Advisor
Other advisors: Associate Professor Robert Boots, Professor Jeffrey Lipman
-
2014
Doctor Philosophy
Improving Antimicrobial Use In Critically Ill Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2012
Master Philosophy
Challenges in management of infections on a burn injury unit.
Associate Advisor
Other advisors: Professor Jeffrey Lipman
Media
Enquiries
Contact Professor Jason Roberts directly for media enquiries about:
- Antibiotics
- Drug dosage
- Therapeutic drug monitoring
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