
Overview
Background
Professor Jason Roberts is Director of the University of Queensland Centre for Clinical Research (UQCCR), an Australian National Health and Medical Research Council (NHMRC) Leadership Fellow L2 at The University of Queensland. He is also a Consultant Clinical Pharmacist at the Royal Brisbane and Women’s Hospital and Interim Director of the Herston Infectious Diseases Institute (HeIDI). He is Director of the NHMRC-funded Centre for Research Excellence RESPOND which is based at UQCCR. He is a clinician-scientist with a strong interest in research and his principal research theme is optimization of antimicrobial dosing in the critically ill. Prof Roberts has authored over 650 published papers and book chapters on this topic, has been awarded over $55 million in grants and has supervised >20 PhD students to completion.
Prof Roberts was recognised as Australia’s leading researcher in two separate categories, Critical Care and Communicable Diseases, by the Australian’s 2019 Research Magazine.
He has been invited to present his results at major international conferences in critical care, infectious diseases, pharmacy, nephrology, transplant and safety. He has served on the Critical Review Panel for ATS/IDSA Guidelines of HAP, HCAP and VAP and the Australian Therapeutic Guidelines - Antibiotic and the 2021 Surviving Sepsis Guidelines. He is the Past Chair of the Working Group for Antimicrobial Use in ICU for the European Society of Intensive Care Medicine and an Executive Member of the PK/PD Group (EPASG) within the European Society for Clinical Microbiology and Infectious Diseases (ESCMID).
He is Section Editor for the International Journal of Antimicrobial Agents and an Associate Editor of the Journal or Pharmacy Practice and Research, the journal for the Society of Hospital Pharmacists of Australia and an Associate Editor for Pharmacotherapy and Aanesthesiology Pain and Critical Care Medicine journal. He has convened >50 seminars/conferences including being co-convenor for Medicines Management 2013, The National Conference for Society of Hospital Pharmacists of Australia.
He also engages with Industry to perform studies that develop optimised antibiotic dosing regimens that maximise antibiotic efficacy for testing in clinical trials or for use in special patient populations (e.g. critically ill, pneumonia, dialysis).
Availability
- Professor Jason Roberts is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours), University of Sydney
- Doctor of Philosophy, The University of Queensland
- Society of Hospital Pharmacists of Australia, Society of Hospital Pharmacists of Australia
Works
Search Professor Jason Roberts’s works on UQ eSpace
2015
Journal Article
Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients
Wong G., Farkas A., Sussman R., Daroczi G., Hope W.W., Lipman J. and Roberts J.A. (2015). Comparison of the accuracy and precision of pharmacokinetic equations to predict free meropenem concentrations in critically ill patients. Antimicrobial Agents and Chemotherapy, 59 (3), 1411-1417. doi: 10.1128/AAC.04001-14
2015
Journal Article
β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study
Donadello, Katia, Antonucci, Elio, Cristallini, Stefano, Roberts, Jason A., Beumier, Marjorie, Scolletta, Sabino, Jacobs, Frederique, Rondelet, Benoit, de Backer, Daniel, Vincent, Jean-Louis and Taccone, Fabio Silvio (2015). β-Lactam pharmacokinetics during extracorporeal membrane oxygenation therapy: A case-control study. International Journal of Antimicrobial Agents, 45 (3), 278-282. doi: 10.1016/j.ijantimicag.2014.11.005
2015
Journal Article
Streamlined research funding using short proposals and accelerated peer review: An observational study
Barnett, Adrian G., Herbert, Danielle L., Campbell, Megan, Daly, Naomi, Roberts, Jason A., Mudge, Alison and Graves, Nicholas (2015). Streamlined research funding using short proposals and accelerated peer review: An observational study. BMC Health Services Research, 15 (1) 55. doi: 10.1186/s12913-015-0721-7
2015
Journal Article
A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans
Parker S.L., Lipman J., Roberts J.A. and Wallis S.C. (2015). A simple LC-MS/MS method using HILIC chromatography for the determination of fosfomycin in plasma and urine: Application to a pilot pharmacokinetic study in humans. Journal of Pharmaceutical and Biomedical Analysis, 105, 39-45. doi: 10.1016/j.jpba.2014.11.042
2015
Journal Article
Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study
Sinnollareddy, Mahipal G., Roberts, Jason A., Lipman, Jeffrey, Akova, Murat, Bassetti, Matteo, De Waele, Jan J., Kaukonen, Kirsi-Maija, Koulenti, Despoina, Martin, Claude, Montravers, Philippe, Rello, Jordi, Rhodes, Andrew, Starr, Therese, Wallis, Steven C. and Dimopoulos, George (2015). Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study. Critical Care, 19 (33) 33, 1-7. doi: 10.1186/s13054-015-0758-3
2015
Journal Article
Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development
Abdul-Aziz, Mohd H., Lipman, Jeffrey, Mouton, Johan W., Hope, William W. and Roberts, Jason A. (2015). Applying Pharmacokinetic/Pharmacodynamic Principles in Critically Ill Patients: Optimizing Efficacy and Reducing Resistance Development. Seminars in Respiratory and Critical Care Medicine, 36 (1), 136-153. doi: 10.1055/s-0034-1398490
2015
Journal Article
Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration
Sinnollareddy, Mahipal G., Roberts, Michael S., Lipman, Jeffrey, Robertson, Thomas A., Peake, Sandra L. and Roberts, Jason A. (2015). Pharmacokinetics of fluconazole in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration. International Journal of Antimicrobial Agents, 45 (2), 192-195. doi: 10.1016/j.ijantimicag.2014.08.013
2015
Journal Article
Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?
Varghese J.M., Jarrett P., Wallis S.C., Boots R.J., Kirkpatrick C.M.J., Lipman J. and Roberts J.A. (2015). Are interstitial fluid concentrations of meropenem equivalent to plasma concentrations in critically ill patients receiving continuous renal replacement therapy?. Journal of Antimicrobial Chemotherapy, 70 (2), 528-533. doi: 10.1093/jac/dku413
2015
Journal Article
Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement
Kanji S., Hayes M., Ling A., Shamseer L., Chant C., Edwards D.J., Edwards S., Ensom M.H.H., Foster D.R., Hardy B., Kiser T.H., La Porte C., Roberts J.A., Shulman R., Walker S., Zelenitsky S. and Moher D. (2015). Reporting Guidelines for Clinical Pharmacokinetic Studies: The ClinPK Statement. Clinical Pharmacokinetics, 54 (7), 783-795. doi: 10.1007/s40262-015-0236-8
2015
Journal Article
Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?
Udy, Andrew A., Lipman, Jeffrey, Jarrett, Paul, Klein, Kerenaftali, Wallis, Steven C., Patel, Kashyap, Kirkpatrick, Carl M. J., Kruger, Peter S., Paterson, David L., Roberts, Michael S. and Roberts, Jason A. (2015). Are standard doses of piperacillin sufficient for critically ill patients with augmented creatinine clearance?. Critical Care, 19 (28) 28, 1-9. doi: 10.1186/s13054-015-0750-y
2015
Journal Article
Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial
Harris, Patrick N. A., Peleg, Anton Y., Iredell, Jon, Ingram, Paul R., Miyakis, Spiros, Stewardson, Andrew J., Rogers, Benjamin A., McBryde, Emma S., Roberts, Jason A., Lipman, Jeff, Athan, Eugene, Paul, Sanjoy K., Baker, Peter, Harris-Brown, Tiffany and Paterson, David L. (2015). Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections due to ceftriaxone non-susceptible Escherichia coli and Klebsiella spp (the MERINO trial): study protocol for a randomised controlled trial. Trials, 16 (1) 24, 24.1-24.8. doi: 10.1186/s13063-014-0541-9
2015
Journal Article
Impact of an inducement to give high doses of amikacin and gentamicin on serum concentrations in critically ill patients with severe sepsis
Roger, C., Louart, B., Muller, L., Roberts, J. A. and Lefrant, J. Y. (2015). Impact of an inducement to give high doses of amikacin and gentamicin on serum concentrations in critically ill patients with severe sepsis. Intensive Care Medicine Experimental , 3 A402. doi: 10.1186/2197-425X-3-S1-A402
2015
Conference Publication
The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting
Abdul-Aziz, M. H., Sulaiman, H., Mat-Nor, M., Rai, V., Wong, K., Hasan, M., Wallis, S., Lipman, J., Staatz, C. E. and Roberts, J. (2015). The BLISS Study: Beta-Lactam Infusion in Severe Sepsis- Randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting. Interscience Conference of Antimicrobial Agents and Chemotherapy (ICAAC), San Diego, CA United States, 17-21 September 2015.
2015
Journal Article
Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring
Cotta, Menino Osbert, Gowen, Belinda, Truloff, Natasha, Bursle, Evan, Mcwhinney, Brett, Ungerer, Jacobus P. J., Roberts, Jason A. and Lipman, Jeffrey (2015). Even high-dose extended infusions may not yield desired concentrations of beta-lactams: the value of therapeutic drug monitoring. Infectious Diseases, 47 (10), 739-742. doi: 10.3109/23744235.2015.1021831
2015
Conference Publication
Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial
Sime, F. B., Roberts, M., Tiong, I. S., Gardner, J., Lehman, S., Peake, S., Hahn, U., Warner, M. and Roberts, J. (2015). Can therapeutic drug monitoring optimise exposure of piperacillin in febrile neutropenic patients with haematological malignancies? A randomised controlled trial. 20th Congress of European Hematology Association, Vienna, Austria, 11-14 June 2015. Pavia, Italy: Fondazione Ferrata Storti.
2015
Journal Article
Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy
Carlier, Mieke, Taccone, Fabio S, Beumier, Majorie, Seyler, Lucie, Cotton, Frederic, Jacobs, Grederique and Roberts, Jason A (2015). Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy. International Journal of Antimicrobial Agents, 46 (4), 413-419. doi: 10.1016/j.ijantimicag.2015.05.020
2015
Journal Article
Linezolid pharmacokinetics in critically ill patients with renal replacement therapy: Comparison of equi-dose of continuous veno-venous haemofiltration with continuous veno-venous haemodiafiltration
Roger, C., Louart, B., Muller, L., Roberts, J. A. and Lefrant, J. Y. (2015). Linezolid pharmacokinetics in critically ill patients with renal replacement therapy: Comparison of equi-dose of continuous veno-venous haemofiltration with continuous veno-venous haemodiafiltration. Intensive Care Medicine Experimental , 3 A631. doi: 10.1186/2197-425X-3-S1-A631
2015
Journal Article
Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration
Jamal, Janattul-Ain, Mat-Nor, Mohd-Basri, Mohamad-Nor, Fariz-Safhan, Udy, Andrew A., Wallis, Steven C., Lipman, Jeffrey and Roberts, Jason A. (2015). Pharmacokinetics of meropenem in critically ill patients receiving continuous venovenous haemofiltration: A randomised controlled trial of continuous infusion versus intermittent bolus administration. International Journal of Antimicrobial Agents, 45 (1), 41-45. doi: 10.1016/j.ijantimicag.2014.09.009
2015
Journal Article
Subtleties in practical application of prolonged infusion of β-lactam antibiotics
De Waele, J.J., Lipman, J., Carlier, M. and Roberts, J.A. (2015). Subtleties in practical application of prolonged infusion of β-lactam antibiotics. International Journal of Antimicrobial Agents, 45 (5) 4517, 461-463. doi: 10.1016/j.ijantimicag.2015.01.007
2015
Journal Article
Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside
Roehr, Anka C., Frey, Otto R., Koeberer, Andreas, Fuchs, Thomas, Roberts, Jason A. and Brinkmann, Alexander (2015). Anti-infective drugs during continuous hemodialysis - using the bench to learn what to do at the bedside. International Journal of Artificial Organs, 38 (1), 17-22. doi: 10.5301/ijao.5000377
Funding
Current funding
Past funding
Supervision
Availability
- Professor Jason Roberts is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Establishing effective antibiotic and sedative dosing in paediatrics with extracorporeal therapies (including extracorporeal membrane oxygenation and renal replacement therapies)
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Honorary Professor Luregn Schlapbach
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Improving drug therapy for children with sepsis and life-threatening infections
Principal Advisor
Other advisors: Honorary Professor Luregn Schlapbach, Dr Sainath Raman
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Pharmacokinetics of anti-mycobacterial drugs in patients with cystic fibrosis
Principal Advisor
Other advisors: Professor Rachel Thomson, Professor Scott Bell
-
Doctor Philosophy
How to use antibiotics better in Paediatric Intensive Care using pharmacokinetic principles
Principal Advisor
Other advisors: Dr Mark Coulthard, Professor Jeffrey Lipman, Dr Xin Liu, Dr Patty Mitre
-
Doctor Philosophy
Perioperative pharmacokinetics of surgical antibiotic prophylaxis
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Professor Andre Van Zundert
-
Doctor Philosophy
Stability of cephalosporin/b-lactam with b-lactamase inhibitor combinations for use in OPAT and simulation of OPAT-like drug exposures in a Biofilm model to assess the effect on MDR isolates.
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
What is the validity of altered dosing approaches for ensuring appropriate antibiotic dosing in the critically ill?
Principal Advisor
-
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
Doctor Philosophy
Suitability of ß-lactam and ß-lactamase inhibitor combinations for use in outpatient parenteral antimicrobial therapy
Principal Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Precision antimicrobial dosing in infected critically ill patients
Principal Advisor
-
Doctor Philosophy
Designing and Implementing a Clinician-Led Protocol for Heparinisation Using Optimal Targets- anti Xa vs APTT
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Intraoperative lignocaine infusions: Development of an optimised infusion dosing regimen for obese patients.
Associate Advisor
Other advisors: Professor Victoria Eley
-
Doctor Philosophy
In vitro evaluation of the impact of different durations of exposure of fast-acting antimicrobials in combination with beta-lactams
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Centre of Research Excellence - REduce the burden of antimicrobial reSistance through oPtimal, persONalised Dosing (RESPOND)
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
Doctor Philosophy
Optimisation of antibiotic regimens for the treatment of resistant infections using dynamic in vitro infections models
Associate Advisor
Other advisors: Dr Fekade Sime
-
Doctor Philosophy
Optimising antibiotic dosing for the treatment and prevention of central nervous system infections
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
Master Philosophy
Designing and implementing a nurse-led electronic medical record (EMR) integrated heparinisation protocol using optimal targets (anti Xa vs APTT)
Associate Advisor
Other advisors: Dr Jessica Schults, Associate Professor Jayesh Dhanani
-
Doctor Philosophy
Optimising the stability and dosing regimens of antibiotics for outpatient parenteral antibiotic therapy
Associate Advisor
Other advisors: Dr Fekade Sime
Completed supervision
-
2025
Doctor Philosophy
Optimising Care of Critically Ill Patients Through Improved Antibiotic Dosing
Principal Advisor
-
2024
Doctor Philosophy
Defining Optimal Dosing Regimens of Colistin and Polymyxin B in Malaysian Patient Populations
Principal Advisor
Other advisors: Dr Hafiz Abdul-Aziz, Dr Fekade Sime
-
2023
Doctor Philosophy
Strategies to improve the use of antimicrobials in hospitalised Indonesian patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman, Dr Hafiz Abdul-Aziz
-
2022
Doctor Philosophy
Evaluation of combination antibiotic regimens for the treatment of multidrug-resistant Acinetobacter baumannii infections
Principal Advisor
Other advisors: Dr Fekade Sime
-
2022
Doctor Philosophy
Microbiological evaluation of piperacillin/tazobactam versus meropenem against extended-spectrum ß-lactamase-producing Escherichia coli
Principal Advisor
Other advisors: Dr Fekade Sime
-
2021
Doctor Philosophy
Optimising antimicrobial dosing in critically ill patients on extracorporeal membrane oxygenation (ECMO)
Principal Advisor
Other advisors: Professor Kiran Shekar, Dr Hafiz Abdul-Aziz
-
2020
Doctor Philosophy
Optimisation of alternative antibiotic dosing regimens for maximal antibacterial activity and suppression of emergence of resistance
Principal Advisor
Other advisors: Dr Fekade Sime
-
2019
Doctor Philosophy
A pharmacokinetic/pharmacodynamic and clinical outcome evaluation of beta-lactam antibiotic therapeutic drug monitoring in critically ill patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2019
Doctor Philosophy
Study of the disposition of nebulized tobramycin
Principal Advisor
Other advisors: Professor John Fraser, Associate Professor Jeremy Cohen
-
2017
Doctor Philosophy
Improving antibiotic dosing in critically ill Australian Indigenous patients with severe sepsis
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Translating Innovative Pharmacokinetic Sampling Techniques into Improved Antibiotic Dosing Regimens in Critically Ill Patients
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2016
Doctor Philosophy
Optimizing beta-lactam antibiotic dosing in critically ill patients: Prolonged infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Dr Christine Staatz, Professor Jeffrey Lipman
-
2015
Doctor Philosophy
ß-lactam antibiotic pharmacokinetics during continuous venovenous haemofiltration in critically ill patients: Continuous infusion versus intermittent bolus administration
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2015
Master Philosophy
Vancomycin-associated nephrotoxicity in the Critically-Ill
Principal Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
The metabolic fate of infused citrate in the critically ill population undergoing continuous renal replacment therapy using regional citrate anticoagulation
Associate Advisor
Other advisors: Professor Bala Venkatesh
-
2024
Doctor Philosophy
Optimising Antibiotic Dosing for Treatment of Nosocomial Central Nervous System Infections in Neurocritical Care Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2024
Doctor Philosophy
Personalising Antimicrobial Therapy in Critically Ill Patients using Bayesian Dosing Software
Associate Advisor
-
2023
Doctor Philosophy
Translating Microsampling Techniques into Improved Antimicrobial Dosing for Critically Ill Children
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2021
Doctor Philosophy
Advanced Oral Antibiotic Formulations
Associate Advisor
Other advisors: Professor Peter Cabot, Professor Amirali Popat, Dr Fekade Sime, Dr James Robert Falconer
-
2017
Master Philosophy
Improving the quality of prescribing in elderly hospital inpatients: evaluating the effect of a clinical pharmacist on ward rounds
Associate Advisor
-
2016
Doctor Philosophy
Sick Patients, Starved Circuits and Sticky Drugs: Understanding pharmacokinetics during extracorporeal membrane oxygenation to optimise drug dosing and improve patient outcomes
Associate Advisor
Other advisors: Professor John Fraser
-
2016
Doctor Philosophy
An Investigation of the Pharmacokinetics of Piperacillin, Meropenem and Fluconazole in Critically Ill Obese Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman, Emeritus Professor Michael Roberts
-
2014
Doctor Philosophy
Improving Antimicrobial Use In Critically Ill Patients
Associate Advisor
Other advisors: Professor Jeffrey Lipman
-
2014
Doctor Philosophy
Dose optimisation of antibiotics during different forms of renal replacement therapy: focus on tissue and target site antibiotic concentrations
Associate Advisor
Other advisors: Associate Professor Robert Boots, Professor Jeffrey Lipman
-
2012
Master Philosophy
Challenges in management of infections on a burn injury unit.
Associate Advisor
Other advisors: Professor Jeffrey Lipman
Media
Enquiries
Contact Professor Jason Roberts directly for media enquiries about:
- Antibiotics
- Drug dosage
- Therapeutic drug monitoring
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