
Overview
Background
Professor Ian Frazer is a clinician scientist, trained as a clinical immunologist in Scotland. As a professor at the University of Queensland, he leads a research group working at TRI in Brisbane, Australia on the immunobiology of epithelial cancers. He is recognised as co-inventor of the technology enabling the HPV vaccines, currently used worldwide to help prevent cervical cancer. He heads a biotechnology company, Jingang Medicine (Aus) Pty Ltd, working on new vaccine technologies, and is a board member of several companies and not for profit organisations. He was the inaugural president of the Australian Academy of Health and Medical Sciences, and a member of the Australian National Science and Technology Council. He chairs the Australian Medical Research Advisory Board of the Medical Research Future Fund.
He was recognised as Australian of the Year in 2006. He was recipient of the Prime Ministers Prize for Science, and of the Balzan Prize, in 2008, and was elected Fellow of the Royal Society of London in 2012. He was appointed Companion of the Order of Australia in the Queen’s Birthday Honours list in 2013.
Availability
- Professor Ian Frazer is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of Edinburgh
- Bachelor of Medicine Surgery, University of Edinburgh
- Doctoral Diploma of Medicine, University of Melbourne
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
- Royal College of Physicians of Edinburgh, Royal College of Physicians of Edinburgh
Works
Search Professor Ian Frazer’s works on UQ eSpace
1998
Journal Article
Histologic and immunohistochemical responses after aortic valve allografts in the rat
Green, Marjorie K., Walsh, Michael D., Dare, Anthony, Hogan, Patrick G., Zhao, Xiao-Ming, Frazer, Ian H., Bansal, Amolak S. and OBrien, Mark F. (1998). Histologic and immunohistochemical responses after aortic valve allografts in the rat. Annals of Thoracic Surgery, 66 (6), S216-S220. doi: 10.1016/S0003-4975(98)01123-0
1997
Journal Article
Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animal
Dunn, Linda A., Evander, Magnus, Tindle, Robert W., Bulloch, Anne Louise, de Kluyver, Rachel L., Fernando, Germain J. P., Lambert, Paul F. and Frazer, Ian H. (1997). Presentation of the HPV16E7 protein by skin grafts is insufficient to allow graft rejection in an E7-primed animal. Virology, 235 (1), 94-103. doi: 10.1006/viro.1997.8650
1997
Journal Article
E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein
Herd, K., Fernando, G. J. P., Dunn, L. A., Frazer, I. H., Lambert, P. and Tindle, R. W. (1997). E7 oncoprotein of human papillomavirus type 16 expressed constitutively in the epidermis has no effect on E7-specific B- or Th-repertoires or on the immune response induced or sustained after immunization with E7 protein. Virology, 231 (1), 155-165. doi: 10.1006/viro.1997.8491
1997
Journal Article
Identification of the alpha(6) integrin as a candidate receptor for papillomaviruses
Evander, Magnus, Frazer, Ian H., Payne, Elizabeth, Qi, Ying Mei, Hengst, Kylie and McMillan, Nigel A.J. (1997). Identification of the alpha(6) integrin as a candidate receptor for papillomaviruses. Journal of Virology, 71 (3), 2449-2456. doi: 10.1128/jvi.71.3.2449-2456.1997
1997
Journal Article
Strategies for immunoprophylaxis and immunotherapy of papillomaviruses
Frazer, I. (1997). Strategies for immunoprophylaxis and immunotherapy of papillomaviruses. Clinics In Dermatology, 15 (2), 285-297. doi: 10.1016/S0738-081X(96)00151-4
1996
Journal Article
Human aortic valve allografts elicit a donor-specific immune response
Hogan, P, Duplock, L, Green, M, Smith, S, Gall, KL, Frazer, IH and OBrien, MF (1996). Human aortic valve allografts elicit a donor-specific immune response. Journal of Thoracic and Cardiovascular Surgery, 112 (5), 1260-1266. doi: 10.1016/S0022-5223(96)70139-3
1996
Journal Article
Immunology of papillomavirus infection
Frazer, IH (1996). Immunology of papillomavirus infection. Current Opinion in Immunology, 8 (4), 484-491. doi: 10.1016/S0952-7915(96)80035-5
1996
Journal Article
Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen
Londono, L. Patricia, Chatfield, Steven, Tindle, Robert W., Herd, Karen, Gao, Xiao-Ming, Frazer, Ian and Dougan, Gordon (1996). Immunisation of mice using Salmonella typhimurium expressing human papillomavirus type 16 E7 epitopes inserted into hepatitis B virus core antigen. Vaccine, 14 (6), 545-552. doi: 10.1016/0264-410X(95)00216-N
1996
Journal Article
Combined therapy trial with interferon alpha-2a and ablative therapy in the treatment of anogential warts
Armstrong, DKB, Maw, RD, Dinsmore, WW, Blaakaer, J, Correa, MAG, Falk, L, Ferenczy, AS, Fortier, M, Frazer, I, Law, C, Moller, BM and Oyakawa, N (1996). Combined therapy trial with interferon alpha-2a and ablative therapy in the treatment of anogential warts. Genitourinary Medicine, 72 (2), 103-107. doi: 10.1136/sti.72.2.103
1996
Journal Article
Familial primary antiphospholipid antibody syndrome
Bansal, AS, Hogan, PG, Gibbs, H and Frazer, IH (1996). Familial primary antiphospholipid antibody syndrome. Arthritis and Rheumatism, 39 (4), 705-706. doi: 10.1002/art.1780390427
1996
Journal Article
How HIV promotes malignancies
Boyle, M.J., Goldstein, D.A., Frazer, I.H. and Sculley, T.B. (1996). How HIV promotes malignancies. Medical Journal of Australia, 164 (4), 230-232.
1996
Journal Article
Epithelial cells display separate receptors for papillomavirus VLPs and for soluble L1 capsid protein
Qi, YM, Peng, SW, Hengst, K, Evander, M, Park, DS, Zhou, J and Frazer, IH (1996). Epithelial cells display separate receptors for papillomavirus VLPs and for soluble L1 capsid protein. Virology, 216 (1), 35-45. doi: 10.1006/viro.1996.0032
1996
Book Chapter
Papovaviridiae: capsid structure and capsid protein function
Zhou, J. and Frazer, I. H. (1996). Papovaviridiae: capsid structure and capsid protein function. Papillomavirus reviews: current research on papillomaviruses. (pp. 93-100) edited by Charles Lacey. Leeds, Yorkshire, United Kingdom: Leeds University Press.
1996
Journal Article
The role of vaccines in the control of STDs: HPV vaccines
Frazer, I. H. (1996). The role of vaccines in the control of STDs: HPV vaccines. Genitourinary Medicine, 72 (6), 398-403. doi: 10.1136/sti.72.6.398
1995
Journal Article
Sequences Required for the Nuclear Targeting and Accumulation of Human Papillomavirus Type 6B L2 Protein
Sun, XY, Frazer, I, Muller, M, Gissmann, L and Zhou, J (1995). Sequences Required for the Nuclear Targeting and Accumulation of Human Papillomavirus Type 6B L2 Protein. Virology, 213 (2) 70005, 321-327. doi: 10.1006/viro.1995.0005
1995
Journal Article
Section review: Biologicals & immunologicals: Human papillomavirus infection, genital warts and cervical cancer: Prospects for prophylactic and therapeutic vaccines
Tindle, Robert W. and Frazer, Ian H. (1995). Section review: Biologicals & immunologicals: Human papillomavirus infection, genital warts and cervical cancer: Prospects for prophylactic and therapeutic vaccines. Expert Opinion on Investigational Drugs, 4 (9), 783-797. doi: 10.1517/13543784.4.9.783
1995
Journal Article
Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease
Frazer, I. H., Leippe, D. M., Dunn, L. A., Liem, A., Tindle, R. W., Fernando, G. J. P., Phelps, W. C. and Lambert, P. F. (1995). Immunological responses in human papillomavirus 16 E6/E7-transgenic mice to E7 protein correlate with the presence of skin disease. Cancer Research, 55 (12), 2635-2639.
1995
Journal Article
Human papillomavirus not found in squamous and large-cell lung carcinomas by polymerase chain-reaction
Fong, K.M., Schonrock, J., Frazer, I.H., Zimmerman, P.V. and Smith, P.J. (1995). Human papillomavirus not found in squamous and large-cell lung carcinomas by polymerase chain-reaction. Cancer, 75 (9), 2400-2401. doi: 10.1002/1097-0142(19950501)75:93.0.CO;2-6
1995
Journal Article
T-helper epitopes of the E7 transforming protein of cervical-cancer associated human papillomavirus type-18 (hpv18)
Fernando, G.J.P., Tindle, R.W and Frazer, I.H. (1995). T-helper epitopes of the E7 transforming protein of cervical-cancer associated human papillomavirus type-18 (hpv18). Virus Research, 36 (1), 1-13. doi: 10.1016/0168-1702(94)00101-H
1995
Journal Article
Papillomavirus Capsid Binding and Uptake by Cells From Different Tissues and Species
Muller, Martin, Gissmann, Lutz, Cristiano, Richard J., Sun, Xiao-Yi, Frazer, Ian H., Jenson, A. Bennet, Alonso, Angel, Zentgraf, Hanswalter and Zhou, Jian (1995). Papillomavirus Capsid Binding and Uptake by Cells From Different Tissues and Species. Journal of Virology, 69 (2), 948-954. doi: 10.1128/jvi.69.2.948-954.1995
Funding
Current funding
Past funding
Supervision
Availability
- Professor Ian Frazer is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
-
Doctor Philosophy
Assessment of predictors of response to checkpoint blockades in cancer patients.
Associate Advisor
Other advisors: Dr Ahmed Mehdi, Dr Janin Chandra, Dr Bree Tillett
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
Completed supervision
-
2024
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of the skin microbiota in cutaneous squamous cell carcinoma
Principal Advisor
Other advisors: Professor Mark Morrison
-
2020
Doctor Philosophy
Modulation of Immune Responses by HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Dr Janin Chandra
-
2018
Doctor Philosophy
Association of Local Immune Suppression in Skin with HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2017
Master Philosophy
Aetiology of Oral Cavity Squamous Cell Carcinoma - An Exploration utilising Next Generation Sequencing
Principal Advisor
-
2015
Doctor Philosophy
Mechanisms of 2,4-Dinitrochlorobenzene-induced acute inflammation in Human Papillomavirus type 16 E7 oncoprotein expressing skin
Principal Advisor
-
2014
Doctor Philosophy
Mechanisms of immunoregulation in human papillomavirus-associated epithelial hyperplasia: of mice and (wo)men
Principal Advisor
Other advisors: Professor Antje Blumenthal
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2013
Doctor Philosophy
LANGERHANS CELLS IN SKIN EXPRESSING HUMAN PAPILLOMAVIRUS TYPE 16 E7
Principal Advisor
-
2010
Doctor Philosophy
CD4+ T cells provide help to CD8+ T cells in immune recall responses in skin
Principal Advisor
-
2010
Doctor Philosophy
Augmenting CD8+ T cell-mediated cutaneous immunotherapy in a murine model system
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2010
Doctor Philosophy
Role of dendritic epidermal T cells in skin graft rejection
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2009
Doctor Philosophy
Human Papillomavirus 16 E7 Inhibits the ability of IFN-γ in Enhancement of MHC Class I Antigen Presentation and CTL Lysis by Affecting IRF-1 Expression in Keratinocytes
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
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2008
Doctor Philosophy
Studies on mechanisms of skin graft rejection
Principal Advisor
Other advisors: Honorary Professor Geoffrey Hill
-
2003
Doctor Philosophy
IMMUNE RESPONSE TO PAPILLOMAVIRUS INFECTION
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2002
Doctor Philosophy
DETERMINING CTL CHARACTERISTICS WHICH CORRELATE WITH TUMOUR REGRESSION IN VIVO
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2023
Doctor Philosophy
Local Delivery Of Immunotherapeutic Antibodies To Skin Cancers
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor Graham Leggatt
-
2022
Doctor Philosophy
Understanding CD4+ T cell responses to HPV16 E7 antigen in a mouse model of precancerous skin
Associate Advisor
Other advisors: Dr Kelvin Tuong, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of CD8+ T cells in the regression of squamous cell carcinoma
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor James Wells
-
2017
Doctor Philosophy
Uncovering novel regulators of CD8+ T-cell function in the skin
Associate Advisor
Other advisors: Associate Professor James Wells
-
2016
Doctor Philosophy
Evaluating CD8+ T-cell function in skin and squamous cell carcinoma following systemic suppression with rapamycin and tacrolimus.
Associate Advisor
Other advisors: Professor Fiona Simpson, Associate Professor James Wells
-
2015
Doctor Philosophy
Characterisation of RP105's divergent functions in macrophage responses to mycobacteria and LPS
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2015
Doctor Philosophy
Contributions of Wnt signalling to immune responses during acute bacterial infection
Associate Advisor
Other advisors: Professor Antje Blumenthal
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2011
Doctor Philosophy
The effects of the balance of Type I and Type II NKT cells on CD8 T cells and Tumour Therapy
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
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2008
Doctor Philosophy
Interactions among Control Beliefs, Illness Severity, Biological Factors and a Psychological Preparation for Heart Surgery: Predictors of Health Outcomes
Associate Advisor
Other advisors: Emeritus Professor Kenneth Pakenham
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2007
Doctor Philosophy
Treatment of Cervical Cancer using RNA-Interference Against Human Papillomavirus Oncogenes
Associate Advisor
-
2005
Doctor Philosophy
Regulation of squamous differentiation by the E2F family transcription factors
Associate Advisor
-
2003
Doctor Philosophy
DENDRITIC CELL IMMUNOTHERAPY BASED ON HUMAN PAPILLOMAVIRUS
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2003
Doctor Philosophy
THE ROLE OF AP2 IN SQUAMOUS DIFFERENTIATION
Associate Advisor
-
2003
Doctor Philosophy
IDENTIFICATION AND CLONING OF GENES ASSOCIATED WITH SQUAMOUS CELL CARCINOMA IN HUMAN SKIN TUMOURS
Associate Advisor
-
Doctor Philosophy
Peripheral Mechanisms of CD8+ T Cell Tolerance in H-2b K14E7 Transgenic Mice
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
Media
Enquiries
Contact Professor Ian Frazer directly for media enquiries about:
- Allergy
- Autoimmune disease
- Cancer - immunity
- Cancer - vaccines to prevent
- Cervical cancer vaccine
- Education - medical
- Genital wart virus disease
- Host-virus interactions
- Immunity
- Immunodeficiency
- Immunology
- Medical education
- Papillomavirus vaccines
- Pathology
- Transplantation immunology
- Tumour immunology
- Tumour vaccines
- Vaccines
- Viral infection
- Viral vaccines
- Viruses
- Warts - genital
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