
Overview
Background
Professor Ian Frazer is a clinician scientist, trained as a clinical immunologist in Scotland. As a professor at the University of Queensland, he leads a research group working at TRI in Brisbane, Australia on the immunobiology of epithelial cancers. He is recognised as co-inventor of the technology enabling the HPV vaccines, currently used worldwide to help prevent cervical cancer. He heads a biotechnology company, Jingang Medicine (Aus) Pty Ltd, working on new vaccine technologies, and is a board member of several companies and not for profit organisations. He was the inaugural president of the Australian Academy of Health and Medical Sciences, and a member of the Australian National Science and Technology Council. He chairs the Australian Medical Research Advisory Board of the Medical Research Future Fund.
He was recognised as Australian of the Year in 2006. He was recipient of the Prime Ministers Prize for Science, and of the Balzan Prize, in 2008, and was elected Fellow of the Royal Society of London in 2012. He was appointed Companion of the Order of Australia in the Queen’s Birthday Honours list in 2013.
Availability
- Professor Ian Frazer is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of Edinburgh
- Bachelor of Medicine Surgery, University of Edinburgh
- Doctoral Diploma of Medicine, University of Melbourne
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
- Royal College of Physicians of Edinburgh, Royal College of Physicians of Edinburgh
Works
Search Professor Ian Frazer’s works on UQ eSpace
1999
Journal Article
Potential strategies utilised by papillomavirus to evade host immunity
Frazer, Ian H., Thomas, Ranjeny, Zhou, Jian A., Leggatt, Graham R., Dunn, Linda, Mcmillan, Nigel A. J., Tindle, Robert W., Filgueira, Luis, Manders, Peter, Barnard, Paula and Sharkey, Michael (1999). Potential strategies utilised by papillomavirus to evade host immunity. Immunological Reviews, 168 (1), 131-142. doi: 10.1111/j.1600-065X.1999.tb01288.x
1999
Journal Article
Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16
Fernando, G. J. P., Murray, B., Zhou, J. and Frazer, I. H. (1999). Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16. Clinical & Experimental Immunology, 115 (3), 397-403. doi: 10.1046/j.1365-2249.1999.00813.x
1999
Book Chapter
Cell mediated immunity to papillomaviruses
Frazer, I. H. and Tindle, R. (1999). Cell mediated immunity to papillomaviruses. Current research on papillomaviruses. (pp. 151-164) edited by Charles Lacey. Leeds, England: Leeds University Press.
1999
Book Chapter
Immunology of HPV infection
Leggatt, G. R. and Frazer, I. H. (1999). Immunology of HPV infection. Vaccines for Human Papillomavirus Infection and Anogenital Disease. (pp. 13-31) edited by Robert W. Tindle. Austin, USA: R. G. Landes Company.
1999
Book
The current status of development of prophylactic vaccines against Human Papillomavirus infection
Frazer, Ian and Vaccine Development Team (1999). The current status of development of prophylactic vaccines against Human Papillomavirus infection. Geneva, Switzerland: World Health Organization.
1999
Journal Article
T cell-mediated and non-specific inflammatory mechanisms contribute to the skin pathology of HPV 16 E6E7 transgenic mice
Hilditch-Maguire, Paige A., Lieppe, Donna M., West, Donna M., Lambert, Paul F. and Frazer, Ian H. (1999). T cell-mediated and non-specific inflammatory mechanisms contribute to the skin pathology of HPV 16 E6E7 transgenic mice. Intervirology, 42 (1), 43-50. doi: 10.1159/000024959
1999
Book Chapter
Safety and Immunogenicity of HPV16 E7/Algammulin
Frazer, I. H., Tindle, R. W., Fernando, G. J., Malcolm, K. M., Herd, K. A., McFadyen, S. M., Cooper, P. D. and Ward, B. G. (1999). Safety and Immunogenicity of HPV16 E7/Algammulin. Vaccines for Human Papillomavirus Infection and Anogenital Disease. (pp. 91-104) edited by R. W. Tindle. Austin, USA: R.G. Landes Company.
1999
Book Chapter
Papillomavirus
Frazer, I. H. and Dunn, L. A. (1999). Papillomavirus. Persistent Viral Infections. (pp. 131-146) edited by Rafi Ahmed and Irvin S.Y. Chen. Chichester, USA: John Wiley & Sons.
1999
Journal Article
T-Helper epitopes identified within the E6 transforming protein of cervical cancer-associated human papillomavirus type 16
Azoury-Ziadeh, Rania, Herd, Karen, Fernando, Germain J. P., Frazer, Ian H. and Tindle, Robert W. (1999). T-Helper epitopes identified within the E6 transforming protein of cervical cancer-associated human papillomavirus type 16. Viral Immunology, 12 (4), 297-312. doi: 10.1089/vim.1999.12.297
1998
Conference Publication
The role of the immune system in anogenital human papillomavirus
Frazer, I. H. (1998). The role of the immune system in anogenital human papillomavirus.
1998
Journal Article
Mucosal immunisation with papillomavirus virus-like particles elicits systemic and mucosal immunity in mice
Liu, Xiao Song, Abdul-Jabbar, Ibtissam, Qi, Ying Mei, Frazer, Ian H. and Zhou, Jian (1998). Mucosal immunisation with papillomavirus virus-like particles elicits systemic and mucosal immunity in mice. Virology, 252 (1), 39-45. doi: 10.1006/viro.1998.9442
1998
Journal Article
The role of the immune system in anogenital human papillomavirus.
Frazer, I H (1998). The role of the immune system in anogenital human papillomavirus.. Australasian Journal of Dermatology, 39 Suppl 1.
1998
Journal Article
Simplifying the molecular mechanisms of human papillomavirus
Saunders, Nicholas A. and Frazer, Ian H. (1998). Simplifying the molecular mechanisms of human papillomavirus. Dermatologic Clinics, 16 (4), 823-827. doi: 10.1016/S0733-8635(05)70054-1
1998
Journal Article
Th2-type CD4(+) cells neither enhance nor suppress antitumor CTL activity in a mouse tumor model
Fernando, Germain J. P., Stewart, Trina J., Tindle, Robert W. and Frazer, Ian H. (1998). Th2-type CD4(+) cells neither enhance nor suppress antitumor CTL activity in a mouse tumor model. Journal of Immunology, 161 (5), 2421-2427.
1998
Journal Article
Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes
Frazer, Ian H., Fernando, Germain J. P., Fowler, Nina, Leggatt, Graham R., Lambert, Paul F., Liem, Amy, Malcolm, Karen and Tindle, Robert W. (1998). Split tolerance to a viral antigen expressed in thymic epithelium and keratinocytes. European Journal of Immunology, 28 (9), 2791-2800. doi: 10.1002/(SICI)1521-4141(199809)28:093.0.CO;2-B
1998
Journal Article
The role of the immune system in human papillomavirus infection
Frazer, I. (1998). The role of the immune system in human papillomavirus infection. Journal of Obstetrics and Gynaecology, 18 (5 Suppl 2), S72-S75. doi: 10.1080/01443619866598
1998
Journal Article
Vaccine-induced Th1-type responses are dominant over Th2-type responses in the short term whereas pre-existing Th2 responses are dominant in the longer term
Fernando, G. J. P., Stewart, T. J., Tindle, R. W. and Frazer, I. H. (1998). Vaccine-induced Th1-type responses are dominant over Th2-type responses in the short term whereas pre-existing Th2 responses are dominant in the longer term. Scandinavian Journal of Immunology, 47 (5), 459-465. doi: 10.1046/j.1365-3083.1998.00327.x
1998
Journal Article
Type specific and genotype cross reactive B epitopes of the L1 protein of HPV16 defined by a panel of monoclonal antibodies
Kulski, Jerzy K., Sadleir, John W., Kelsall, Stephen R., Cicchini, Maria S., Shellam, Geoffrey, Peng, Shi Wen, Qi, Ying Mei, Galloway, Denise A., Zhou, Jian and Frazer, Ian H. (1998). Type specific and genotype cross reactive B epitopes of the L1 protein of HPV16 defined by a panel of monoclonal antibodies. Virology, 243 (2), 275-282. doi: 10.1006/viro.1997.9011
1998
Journal Article
DNA packaging by L1 and L2 capsid proteins of bovine papillomavirus type 1
Zhao, Kong-Nan, Sun, Xiao-Yi, Frazer, Ian H. and Zhou, Jian (1998). DNA packaging by L1 and L2 capsid proteins of bovine papillomavirus type 1. Virology, 243 (2), 482-491. doi: 10.1006/viro.1998.9091
1998
Journal Article
Papillomavirus virus-like particles can deliver defined CTL epitopes to the MHC class I pathway
Peng, Shiwen W., Frazer, Ian H., Fernando, Germain J. P. and Zhou, Jian (1998). Papillomavirus virus-like particles can deliver defined CTL epitopes to the MHC class I pathway. Virology, 240 (1), 147-157. doi: 10.1006/viro.1997.8912
Funding
Current funding
Past funding
Supervision
Availability
- Professor Ian Frazer is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
Assessment of predictors of response to checkpoint blockades in cancer patients.
Associate Advisor
Other advisors: Dr Ahmed Mehdi, Dr Janin Chandra, Dr Bree Tillett
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
Completed supervision
-
2024
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of the skin microbiota in cutaneous squamous cell carcinoma
Principal Advisor
Other advisors: Professor Mark Morrison
-
2020
Doctor Philosophy
Modulation of Immune Responses by HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Dr Janin Chandra
-
2018
Doctor Philosophy
Association of Local Immune Suppression in Skin with HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2017
Master Philosophy
Aetiology of Oral Cavity Squamous Cell Carcinoma - An Exploration utilising Next Generation Sequencing
Principal Advisor
-
2015
Doctor Philosophy
Mechanisms of 2,4-Dinitrochlorobenzene-induced acute inflammation in Human Papillomavirus type 16 E7 oncoprotein expressing skin
Principal Advisor
-
2014
Doctor Philosophy
Mechanisms of immunoregulation in human papillomavirus-associated epithelial hyperplasia: of mice and (wo)men
Principal Advisor
Other advisors: Professor Antje Blumenthal
-
2013
Doctor Philosophy
LANGERHANS CELLS IN SKIN EXPRESSING HUMAN PAPILLOMAVIRUS TYPE 16 E7
Principal Advisor
-
2010
Doctor Philosophy
CD4+ T cells provide help to CD8+ T cells in immune recall responses in skin
Principal Advisor
-
2010
Doctor Philosophy
Augmenting CD8+ T cell-mediated cutaneous immunotherapy in a murine model system
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2010
Doctor Philosophy
Role of dendritic epidermal T cells in skin graft rejection
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2009
Doctor Philosophy
Human Papillomavirus 16 E7 Inhibits the ability of IFN-γ in Enhancement of MHC Class I Antigen Presentation and CTL Lysis by Affecting IRF-1 Expression in Keratinocytes
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
-
2008
Doctor Philosophy
Studies on mechanisms of skin graft rejection
Principal Advisor
Other advisors: Honorary Professor Geoffrey Hill
-
2003
Doctor Philosophy
IMMUNE RESPONSE TO PAPILLOMAVIRUS INFECTION
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2002
Doctor Philosophy
DETERMINING CTL CHARACTERISTICS WHICH CORRELATE WITH TUMOUR REGRESSION IN VIVO
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2023
Doctor Philosophy
Local Delivery Of Immunotherapeutic Antibodies To Skin Cancers
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor Graham Leggatt
-
2022
Doctor Philosophy
Understanding CD4+ T cell responses to HPV16 E7 antigen in a mouse model of precancerous skin
Associate Advisor
Other advisors: Dr Kelvin Tuong, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of CD8+ T cells in the regression of squamous cell carcinoma
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor James Wells
-
2017
Doctor Philosophy
Uncovering novel regulators of CD8+ T-cell function in the skin
Associate Advisor
Other advisors: Associate Professor James Wells
-
2016
Doctor Philosophy
Evaluating CD8+ T-cell function in skin and squamous cell carcinoma following systemic suppression with rapamycin and tacrolimus.
Associate Advisor
Other advisors: Professor Fiona Simpson, Associate Professor James Wells
-
2015
Doctor Philosophy
Characterisation of RP105's divergent functions in macrophage responses to mycobacteria and LPS
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2015
Doctor Philosophy
Contributions of Wnt signalling to immune responses during acute bacterial infection
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2011
Doctor Philosophy
The effects of the balance of Type I and Type II NKT cells on CD8 T cells and Tumour Therapy
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
-
2008
Doctor Philosophy
Interactions among Control Beliefs, Illness Severity, Biological Factors and a Psychological Preparation for Heart Surgery: Predictors of Health Outcomes
Associate Advisor
Other advisors: Emeritus Professor Kenneth Pakenham
-
2007
Doctor Philosophy
Treatment of Cervical Cancer using RNA-Interference Against Human Papillomavirus Oncogenes
Associate Advisor
-
2005
Doctor Philosophy
Regulation of squamous differentiation by the E2F family transcription factors
Associate Advisor
-
2003
Doctor Philosophy
DENDRITIC CELL IMMUNOTHERAPY BASED ON HUMAN PAPILLOMAVIRUS
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2003
Doctor Philosophy
IDENTIFICATION AND CLONING OF GENES ASSOCIATED WITH SQUAMOUS CELL CARCINOMA IN HUMAN SKIN TUMOURS
Associate Advisor
-
2003
Doctor Philosophy
THE ROLE OF AP2 IN SQUAMOUS DIFFERENTIATION
Associate Advisor
-
Doctor Philosophy
Peripheral Mechanisms of CD8+ T Cell Tolerance in H-2b K14E7 Transgenic Mice
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
Media
Enquiries
Contact Professor Ian Frazer directly for media enquiries about:
- Allergy
- Autoimmune disease
- Cancer - immunity
- Cancer - vaccines to prevent
- Cervical cancer vaccine
- Education - medical
- Genital wart virus disease
- Host-virus interactions
- Immunity
- Immunodeficiency
- Immunology
- Medical education
- Papillomavirus vaccines
- Pathology
- Transplantation immunology
- Tumour immunology
- Tumour vaccines
- Vaccines
- Viral infection
- Viral vaccines
- Viruses
- Warts - genital
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: