
Overview
Background
Professor Ian Frazer is a clinician scientist, trained as a clinical immunologist in Scotland. As a professor at the University of Queensland, he leads a research group working at TRI in Brisbane, Australia on the immunobiology of epithelial cancers. He is recognised as co-inventor of the technology enabling the HPV vaccines, currently used worldwide to help prevent cervical cancer. He heads a biotechnology company, Jingang Medicine (Aus) Pty Ltd, working on new vaccine technologies, and is a board member of several companies and not for profit organisations. He was the inaugural president of the Australian Academy of Health and Medical Sciences, and a member of the Australian National Science and Technology Council. He chairs the Australian Medical Research Advisory Board of the Medical Research Future Fund.
He was recognised as Australian of the Year in 2006. He was recipient of the Prime Ministers Prize for Science, and of the Balzan Prize, in 2008, and was elected Fellow of the Royal Society of London in 2012. He was appointed Companion of the Order of Australia in the Queen’s Birthday Honours list in 2013.
Availability
- Professor Ian Frazer is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of Edinburgh
- Bachelor of Medicine Surgery, University of Edinburgh
- Doctoral Diploma of Medicine, University of Melbourne
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
- Royal College of Physicians of Edinburgh, Royal College of Physicians of Edinburgh
Works
Search Professor Ian Frazer’s works on UQ eSpace
1993
Journal Article
Synthesis and Assembly of Infectious Bovine Papillomavirus Particles Invitro
Zhou, J, Stenzel, DJ, Sun, XY and Frazer, IH (1993). Synthesis and Assembly of Infectious Bovine Papillomavirus Particles Invitro. Journal of General Virology, 74 (4), 763-768. doi: 10.1099/0022-1317-74-4-763
1993
Journal Article
Transmission of Human Papillomaviruses From Mother to Child
Fredericks, BD, Balkin, A, Daniel, HW, Schonrock, J, Ward, B and Frazer, IH (1993). Transmission of Human Papillomaviruses From Mother to Child. Australian & New Zealand Journal of Obstetrics & Gynaecology, 33 (1), 30-32. doi: 10.1111/j.1479-828X.1993.tb02047.x
1993
Conference Publication
Adjuvants Can Bias to Th1 or Th2 the Immune-Response to Hpv E7 Protein in Mice
Fernando, G. J., Zhou, J., Tindle, R. W. and Frazer, I. H. (1993). Adjuvants Can Bias to Th1 or Th2 the Immune-Response to Hpv E7 Protein in Mice. -, -, 1993. BETHESDA: Wiley-Blackwell.
1993
Conference Publication
Antigen Presentation as a Determinant of the Outcome of Papillomavirus Infection
Frazer, IH (1993). Antigen Presentation as a Determinant of the Outcome of Papillomavirus Infection.
1993
Journal Article
To the editor [3]
Hare, A. and Frazer, I. (1993). To the editor [3]. Australian and New Zealand Journal of Obstetrics and Gynaecology, 33 (4)
1993
Conference Publication
Precursors of Cervical-Cancer - the Male Factor
Oconnor, DT, Frazer, I and Kennedy, L (1993). Precursors of Cervical-Cancer - the Male Factor. 7Th World Congress of Cervical Pathology and Colposcopy, Rome Italy, May , 1990.
1993
Conference Publication
An Improved Immunoassay for the E7 Protein of Hpv16
Dunn, L. A., Tindle, R. W., Fernando, G. J. and Frazer, I. H. (1993). An Improved Immunoassay for the E7 Protein of Hpv16. -, -, 1993. BETHESDA: Wiley-Blackwell.
1993
Conference Publication
Use of Recombinant Hepatitis-B Core Antigen Particles to Deliver Hpv16-E7 Immunogenic Signals
Tindle, R., Londono, P., Herd, K., Frazer, I. and Dougan, G. (1993). Use of Recombinant Hepatitis-B Core Antigen Particles to Deliver Hpv16-E7 Immunogenic Signals. -, -, -. Oxford, United Kingdom: John Wiley & Sons.
1993
Journal Article
HPV DNA in oropharyngeal squamous cell cancers: Comparison of results from four DNA detection methods
Frazer, I. H., Leonard, J. H., Schonrock, J., Wright, R. G. and Kearsley, J. H. (1993). HPV DNA in oropharyngeal squamous cell cancers: Comparison of results from four DNA detection methods. Pathology, 25 (2), 138-143. doi: 10.3109/00313029309084788
1993
Journal Article
Localized granulomatous epiglottitis
Hetterich, F., Suthers, M., Wells, J., Coman, W., Frazer, I. and Hogan, P. (1993). Localized granulomatous epiglottitis. Australian Journal of Otolaryngology, 1 (4), 369-371.
1993
Conference Publication
A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer
Frazer, I. H., Lieppe, D., Lambert, P., Griep, A., Tindle, R. W. and Fernando, G. (1993). A Transgenic Mouse Model of the Immunobiology of Hpv16 Induced Cervical-Cancer. -, -, 1993. BETHESDA: FEDERATION AMER SOC EXP BIOL.
1992
Journal Article
Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls
Tindle, Robert W., Murray, Barbara, Herd, Karen, Kennedy, Lynn, O'Connor, Dan T., Fernando, Germain J. P. and Frazer, Ian H. (1992). Humoral immune response to the E7 open reading frame protein of human papillomavirus genotype 16 in subjects with anogenital papillomavirus infection and controls. Immunology and Infections Diseases, 2, 223-228.
1992
Journal Article
Definition of Linear Antigenic Regions of the Hpv16 L1-Capsid Protein Using Synthetic Virion-Like Particles
Zhou, J, Sun, XY, Davies, H, Crawford, L, Park, D and Frazer, IH (1992). Definition of Linear Antigenic Regions of the Hpv16 L1-Capsid Protein Using Synthetic Virion-Like Particles. Virology, 189 (2), 592-599. doi: 10.1016/0042-6822(92)90582-A
1992
Journal Article
The vaccinia virus K2L gene encodes a serine protease inhibitor which inhibits cell-cell fusion
Zhou, J., Sun, X. Y., Fernando, G. J. P. and Frazer, I. H. (1992). The vaccinia virus K2L gene encodes a serine protease inhibitor which inhibits cell-cell fusion. Virology, 189 (2), 678-686. doi: 10.1016/0042-6822(92)90591-C
1992
Journal Article
Human Papillomaviruses in Normal Oral-Mucosa - a Comparison of Methods for Sample Collection
Lawton, G, Thomas, S, Schonrock, J, Monsour, F and Frazer, I (1992). Human Papillomaviruses in Normal Oral-Mucosa - a Comparison of Methods for Sample Collection. Journal of Oral Pathology & Medicine, 21 (6), 265-269. doi: 10.1111/j.1600-0714.1992.tb01008.x
1992
Journal Article
An Elisa Capture Assay for the E7 Transforming Proteins of Hpv16 and Hpv18
Selvey, L. A., Dunn, L. A., Murray, B., Tindle, R. W. and Frazer, I. H. (1992). An Elisa Capture Assay for the E7 Transforming Proteins of Hpv16 and Hpv18. Journal of Virological Methods, 37 (2), 119-128. doi: 10.1016/0166-0934(92)90039-G
1991
Journal Article
Identification of the Nuclear-Localization Signal of Human Papillomavirus Type-16 L1-Protein
Zhou, J, Doorbar, J, Sun, XY, Crawford, LV, McLean, CS and Frazer, IH (1991). Identification of the Nuclear-Localization Signal of Human Papillomavirus Type-16 L1-Protein. Virology, 185 (2), 625-632. doi: 10.1016/0042-6822(91)90533-H
1991
Journal Article
Expression of Vaccinia Recombinant Hpv 16 L1 and L2 Orf Proteins in Epithelial-Cells Is Sufficient for Assembly of Hpv Virion-Like Particles
Zhou, J, Sun, XY, Stenzel, DJ and Frazer, IH (1991). Expression of Vaccinia Recombinant Hpv 16 L1 and L2 Orf Proteins in Epithelial-Cells Is Sufficient for Assembly of Hpv Virion-Like Particles. Virology, 185 (1), 251-257. doi: 10.1016/0042-6822(91)90772-4
1991
Journal Article
The Hygromycin-Resistance-Encoding Gene as a Selection Marker for Vaccinia Virus Recombinants
Zhou, J, Crawford, L, Sun, XY and Frazer, IH (1991). The Hygromycin-Resistance-Encoding Gene as a Selection Marker for Vaccinia Virus Recombinants. Gene, 107 (2), 307-312. doi: 10.1016/0378-1119(91)90331-5
1991
Journal Article
Zinc deficiency and the short bowel syndrome
Terry, S. I., Ford, M. J., Sircus, W., Suttle, N. F., Frazer, I. and Munro, J. F. (1991). Zinc deficiency and the short bowel syndrome. Journal of Trace Elements in Experimental Medicine, 4 (2), 85-88.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Ian Frazer is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
-
Doctor Philosophy
Assessment of predictors of response to checkpoint blockades in cancer patients.
Associate Advisor
Other advisors: Dr Ahmed Mehdi, Dr Janin Chandra, Dr Bree Tillett
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
Completed supervision
-
2024
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of the skin microbiota in cutaneous squamous cell carcinoma
Principal Advisor
Other advisors: Professor Mark Morrison
-
2020
Doctor Philosophy
Modulation of Immune Responses by HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Dr Janin Chandra
-
2018
Doctor Philosophy
Association of Local Immune Suppression in Skin with HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2017
Master Philosophy
Aetiology of Oral Cavity Squamous Cell Carcinoma - An Exploration utilising Next Generation Sequencing
Principal Advisor
-
2015
Doctor Philosophy
Mechanisms of 2,4-Dinitrochlorobenzene-induced acute inflammation in Human Papillomavirus type 16 E7 oncoprotein expressing skin
Principal Advisor
-
2014
Doctor Philosophy
Mechanisms of immunoregulation in human papillomavirus-associated epithelial hyperplasia: of mice and (wo)men
Principal Advisor
Other advisors: Professor Antje Blumenthal
-
2013
Doctor Philosophy
LANGERHANS CELLS IN SKIN EXPRESSING HUMAN PAPILLOMAVIRUS TYPE 16 E7
Principal Advisor
-
2010
Doctor Philosophy
CD4+ T cells provide help to CD8+ T cells in immune recall responses in skin
Principal Advisor
-
2010
Doctor Philosophy
Augmenting CD8+ T cell-mediated cutaneous immunotherapy in a murine model system
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2010
Doctor Philosophy
Role of dendritic epidermal T cells in skin graft rejection
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2009
Doctor Philosophy
Human Papillomavirus 16 E7 Inhibits the ability of IFN-γ in Enhancement of MHC Class I Antigen Presentation and CTL Lysis by Affecting IRF-1 Expression in Keratinocytes
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
-
2008
Doctor Philosophy
Studies on mechanisms of skin graft rejection
Principal Advisor
Other advisors: Honorary Professor Geoffrey Hill
-
2003
Doctor Philosophy
IMMUNE RESPONSE TO PAPILLOMAVIRUS INFECTION
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2002
Doctor Philosophy
DETERMINING CTL CHARACTERISTICS WHICH CORRELATE WITH TUMOUR REGRESSION IN VIVO
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2023
Doctor Philosophy
Local Delivery Of Immunotherapeutic Antibodies To Skin Cancers
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor Graham Leggatt
-
2022
Doctor Philosophy
Understanding CD4+ T cell responses to HPV16 E7 antigen in a mouse model of precancerous skin
Associate Advisor
Other advisors: Dr Kelvin Tuong, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of CD8+ T cells in the regression of squamous cell carcinoma
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor James Wells
-
2017
Doctor Philosophy
Uncovering novel regulators of CD8+ T-cell function in the skin
Associate Advisor
Other advisors: Associate Professor James Wells
-
2016
Doctor Philosophy
Evaluating CD8+ T-cell function in skin and squamous cell carcinoma following systemic suppression with rapamycin and tacrolimus.
Associate Advisor
Other advisors: Professor Fiona Simpson, Associate Professor James Wells
-
2015
Doctor Philosophy
Characterisation of RP105's divergent functions in macrophage responses to mycobacteria and LPS
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2015
Doctor Philosophy
Contributions of Wnt signalling to immune responses during acute bacterial infection
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2011
Doctor Philosophy
The effects of the balance of Type I and Type II NKT cells on CD8 T cells and Tumour Therapy
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
-
2008
Doctor Philosophy
Interactions among Control Beliefs, Illness Severity, Biological Factors and a Psychological Preparation for Heart Surgery: Predictors of Health Outcomes
Associate Advisor
Other advisors: Emeritus Professor Kenneth Pakenham
-
2007
Doctor Philosophy
Treatment of Cervical Cancer using RNA-Interference Against Human Papillomavirus Oncogenes
Associate Advisor
-
2005
Doctor Philosophy
Regulation of squamous differentiation by the E2F family transcription factors
Associate Advisor
-
2003
Doctor Philosophy
DENDRITIC CELL IMMUNOTHERAPY BASED ON HUMAN PAPILLOMAVIRUS
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2003
Doctor Philosophy
IDENTIFICATION AND CLONING OF GENES ASSOCIATED WITH SQUAMOUS CELL CARCINOMA IN HUMAN SKIN TUMOURS
Associate Advisor
-
2003
Doctor Philosophy
THE ROLE OF AP2 IN SQUAMOUS DIFFERENTIATION
Associate Advisor
-
Doctor Philosophy
Peripheral Mechanisms of CD8+ T Cell Tolerance in H-2b K14E7 Transgenic Mice
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
Media
Enquiries
Contact Professor Ian Frazer directly for media enquiries about:
- Allergy
- Autoimmune disease
- Cancer - immunity
- Cancer - vaccines to prevent
- Cervical cancer vaccine
- Education - medical
- Genital wart virus disease
- Host-virus interactions
- Immunity
- Immunodeficiency
- Immunology
- Medical education
- Papillomavirus vaccines
- Pathology
- Transplantation immunology
- Tumour immunology
- Tumour vaccines
- Vaccines
- Viral infection
- Viral vaccines
- Viruses
- Warts - genital
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