
Overview
Background
Professor Ian Frazer is a clinician scientist, trained as a clinical immunologist in Scotland. As a professor at the University of Queensland, he leads a research group working at TRI in Brisbane, Australia on the immunobiology of epithelial cancers. He is recognised as co-inventor of the technology enabling the HPV vaccines, currently used worldwide to help prevent cervical cancer. He heads a biotechnology company, Jingang Medicine (Aus) Pty Ltd, working on new vaccine technologies, and is a board member of several companies and not for profit organisations. He was the inaugural president of the Australian Academy of Health and Medical Sciences, and a member of the Australian National Science and Technology Council. He chairs the Australian Medical Research Advisory Board of the Medical Research Future Fund.
He was recognised as Australian of the Year in 2006. He was recipient of the Prime Ministers Prize for Science, and of the Balzan Prize, in 2008, and was elected Fellow of the Royal Society of London in 2012. He was appointed Companion of the Order of Australia in the Queen’s Birthday Honours list in 2013.
Availability
- Professor Ian Frazer is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of Edinburgh
- Bachelor of Medicine Surgery, University of Edinburgh
- Doctoral Diploma of Medicine, University of Melbourne
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
- Royal College of Physicians of Edinburgh, Royal College of Physicians of Edinburgh
Works
Search Professor Ian Frazer’s works on UQ eSpace
1991
Journal Article
A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes
Tindle, Robert W., Fernando, Germain J. P., Sterling, Jane C. and Frazer, Ian H. (1991). A 'public' T-helper epitope of the E7 transforming protein of human papillomavirus 16 provides cognate help for several E7 B-cell epitopes from cervical cancer-associated human papillomavirus genotypes. Proceedings of the National Academy of Sciences of the United States of America, 88 (13), 5887-5891. doi: 10.1073/pnas.88.13.5887
1990
Journal Article
Identification of B-Epitopes in the Human Papillomavirus-18 E7 Open Reading Frame Protein
Selvey, L. A., Tindle, R. W., Geysen, H. M., Haller, C. J., Smith, J. A. and Frazer, I. H. (1990). Identification of B-Epitopes in the Human Papillomavirus-18 E7 Open Reading Frame Protein. Journal of Immunology, 145 (9), 3105-3110.
1990
Journal Article
Immunology of Anogenital Human Papillomavirus (Hpv) Infection
Tindle, R. W. and Frazer, I. H. (1990). Immunology of Anogenital Human Papillomavirus (Hpv) Infection. Australian & New Zealand Journal of Obstetrics & Gynaecology, 30 (4), 370-375. doi: 10.1111/j.1479-828X.1990.tb02033.x
1990
Journal Article
Major Population Differences in T-Cell Response to a Malaria Sporozoite Vaccine Candidate
Zevering, Y, Houghten, RA, Frazer, IH and Good, MF (1990). Major Population Differences in T-Cell Response to a Malaria Sporozoite Vaccine Candidate. International Immunology, 2 (10), 945-955. doi: 10.1093/intimm/2.10.945
1990
Journal Article
Humoral response to human papillomavirus genotype 16 and 18 open reading frame antigens in subjects with anogenital papillomavirus infection and controls
Smillie, Anne E., Tindle, Robert W., O'Connor, Dan T., Kennedy, Lynn and Frazer, Ian H. (1990). Humoral response to human papillomavirus genotype 16 and 18 open reading frame antigens in subjects with anogenital papillomavirus infection and controls. Immunology & Infections Diseases, 1, 13-17.
1990
Journal Article
The molecular specificity of linear B-epitopes in the E7 open reading frame protein of human papillomavirus 16 defined by monoclonal antibodies
Tindle, R. W., Zhou, W. D., Saul, A. and Frazer, I. H. (1990) The molecular specificity of linear B-epitopes in the E7 open reading frame protein of human papillomavirus 16 defined by monoclonal antibodies. Peptide Research, 3 4: 162-166.
1990
Journal Article
Identification of B Epitopes in Human Papillomavirus Type-16 E7 Open Reading Frame Protein
Tindle, R. W., Smith, J. A., Geysen, H. M., Selvey, L. A. and Frazer, I. H. (1990). Identification of B Epitopes in Human Papillomavirus Type-16 E7 Open Reading Frame Protein. Journal of General Virology, 71 (6), 1347-1354. doi: 10.1099/0022-1317-71-6-1347
1990
Journal Article
Lymphocyte Ectoenzyme Activity Compared in Healthy-Persons and Patients Seropositive to or At High-Risk of Hiv-Infection
Chalmers, AH, Hare, C, Woolley, G and Frazer, IH (1990). Lymphocyte Ectoenzyme Activity Compared in Healthy-Persons and Patients Seropositive to or At High-Risk of Hiv-Infection. Immunology and Cell Biology, 68 (2), 81-85. doi: 10.1038/icb.1990.12
1990
Journal Article
A NEONATALLY TOLERANT MOUSE MODEL TO ASSESS PATHOGENICITY OF HUMAN AUTOANTIBODIES
MUNDLOS, S, MACKAY, IR, FRAZER, IH and ROWLEY, M (1990). A NEONATALLY TOLERANT MOUSE MODEL TO ASSESS PATHOGENICITY OF HUMAN AUTOANTIBODIES. Journal of Immunological Methods, 127 (2), 279-284. doi: 10.1016/0022-1759(90)90079-B
1990
Journal Article
Immunology of Papillomavirus Infection of the Human Anogenital Epithelium
Tindle, R. W., Park, D. and Frazer, I. H. (1990). Immunology of Papillomavirus Infection of the Human Anogenital Epithelium. Journal of Gynecologic Surgery, 6 (1), 11-21. doi: 10.1089/gyn.1990.6.11
1989
Journal Article
Cerebral-Dysfunction with Evidence of Cerebral Hiv Infection Amongst Asymptomatic Hiv Seropositive Subjects
Field, M, Tate, J, Kunze, H and Frazer, IH (1989). Cerebral-Dysfunction with Evidence of Cerebral Hiv Infection Amongst Asymptomatic Hiv Seropositive Subjects. Australian and New Zealand Journal of Medicine, 19 (6), 694-699. doi: 10.1111/j.1445-5994.1989.tb00337.x
1989
Journal Article
DEPRESSED ACTIVITIES OF PURINE ENZYMES IN LYMPHOCYTES OF PATIENTS INFECTED WITH HUMAN IMMUNODEFICIENCY VIRUS
RENOUF, JA, WOOD, A, FRAZER, IH, THONG, YH and CHALMERS, AH (1989). DEPRESSED ACTIVITIES OF PURINE ENZYMES IN LYMPHOCYTES OF PATIENTS INFECTED WITH HUMAN IMMUNODEFICIENCY VIRUS. Clinical Chemistry, 35 (7), 1478-1481.
1989
Journal Article
Male partners of women with genital human papillomavirus infection - an assessment of colposcopic abnormalities by histological examination and human papillomavirus hybridization
Selvey, L., Buntine, D.W., Kennedy, L. and Frazer, I.H. (1989). Male partners of women with genital human papillomavirus infection - an assessment of colposcopic abnormalities by histological examination and human papillomavirus hybridization. Medical Journal of Australia, 150 (9), 479-&. doi: 10.5694/j.1326-5377.1989.tb136590.x
1989
Journal Article
Foscarnet Infusion At Home
Wood, G, Whitby, M, Hogan, P and Frazer, I (1989). Foscarnet Infusion At Home. Lancet, 1 (8630), 156-156.
1988
Journal Article
Influence of human immunodeficiency virus-antibody testing on sexual-behavior in a high-risk population from a low-risk city
Frazer, I.H., McCamish, M., Hay, I. and North, P. (1988). Influence of human immunodeficiency virus-antibody testing on sexual-behavior in a high-risk population from a low-risk city. Medical Journal of Australia, 149 (7), 365-368. doi: 10.5694/j.1326-5377.1988.tb120670.x
1988
Journal Article
A Biometrical View On Normal Values of Cd4 and Cd8 Lymphocyte Counts in Peripheral-Blood
Zachar, V, Mikulecky, M, Mayer, V, Mackay, I and Frazer, I (1988). A Biometrical View On Normal Values of Cd4 and Cd8 Lymphocyte Counts in Peripheral-Blood. Pathology, 20 (4), 358-360. doi: 10.3109/00313028809085219
1988
Journal Article
Human papillomavirus - a study of male sexual partners
Kennedy, L., Buntine, D.W., Oconnor, D. and Frazer, I.H. (1988). Human papillomavirus - a study of male sexual partners. Medical Journal of Australia, 149 (6), 309-311. doi: 10.5694/j.1326-5377.1988.tb120630.x
1988
Journal Article
Some Adverse Reactions to Allopurinol May Be Mediated by Lymphocyte-Reactivity to Oxypurinol
Emmerson, BT, Hazelton, RA and Frazer, IH (1988). Some Adverse Reactions to Allopurinol May Be Mediated by Lymphocyte-Reactivity to Oxypurinol. Arthritis and Rheumatism, 31 (3), 436-440. doi: 10.1002/art.1780310318
1988
Journal Article
AIDS-associated psoriasis responds to azidothymidine
Feeney, G.F. and Frazer, I. (1988). AIDS-associated psoriasis responds to azidothymidine. Medical Journal of Australia, 148 (3), 155-155.
1987
Journal Article
Intramuscular versus low-dose intradermal hepatitis B vaccine. Assessment by humoral and cellular immune response to hepatitis B surface antigen
Frazer, I.H., Jones, B., Dimitrakakis, M. and Mackay, I.R. (1987). Intramuscular versus low-dose intradermal hepatitis B vaccine. Assessment by humoral and cellular immune response to hepatitis B surface antigen. Medical Journal of Australia, 146 (5), 242-245. doi: 10.5694/j.1326-5377.1987.tb120230.x
Funding
Current funding
Past funding
Supervision
Availability
- Professor Ian Frazer is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
-
Doctor Philosophy
Assessment of predictors of response to checkpoint blockades in cancer patients.
Associate Advisor
Other advisors: Dr Ahmed Mehdi, Dr Janin Chandra, Dr Bree Tillett
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
Completed supervision
-
2024
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of the skin microbiota in cutaneous squamous cell carcinoma
Principal Advisor
Other advisors: Professor Mark Morrison
-
2020
Doctor Philosophy
Modulation of Immune Responses by HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Dr Janin Chandra
-
2018
Doctor Philosophy
Association of Local Immune Suppression in Skin with HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2017
Master Philosophy
Aetiology of Oral Cavity Squamous Cell Carcinoma - An Exploration utilising Next Generation Sequencing
Principal Advisor
-
2015
Doctor Philosophy
Mechanisms of 2,4-Dinitrochlorobenzene-induced acute inflammation in Human Papillomavirus type 16 E7 oncoprotein expressing skin
Principal Advisor
-
2014
Doctor Philosophy
Mechanisms of immunoregulation in human papillomavirus-associated epithelial hyperplasia: of mice and (wo)men
Principal Advisor
Other advisors: Professor Antje Blumenthal
-
2013
Doctor Philosophy
LANGERHANS CELLS IN SKIN EXPRESSING HUMAN PAPILLOMAVIRUS TYPE 16 E7
Principal Advisor
-
2010
Doctor Philosophy
CD4+ T cells provide help to CD8+ T cells in immune recall responses in skin
Principal Advisor
-
2010
Doctor Philosophy
Augmenting CD8+ T cell-mediated cutaneous immunotherapy in a murine model system
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2010
Doctor Philosophy
Role of dendritic epidermal T cells in skin graft rejection
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2009
Doctor Philosophy
Human Papillomavirus 16 E7 Inhibits the ability of IFN-γ in Enhancement of MHC Class I Antigen Presentation and CTL Lysis by Affecting IRF-1 Expression in Keratinocytes
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
-
2008
Doctor Philosophy
Studies on mechanisms of skin graft rejection
Principal Advisor
Other advisors: Honorary Professor Geoffrey Hill
-
2003
Doctor Philosophy
IMMUNE RESPONSE TO PAPILLOMAVIRUS INFECTION
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2002
Doctor Philosophy
DETERMINING CTL CHARACTERISTICS WHICH CORRELATE WITH TUMOUR REGRESSION IN VIVO
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2023
Doctor Philosophy
Local Delivery Of Immunotherapeutic Antibodies To Skin Cancers
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor Graham Leggatt
-
2022
Doctor Philosophy
Understanding CD4+ T cell responses to HPV16 E7 antigen in a mouse model of precancerous skin
Associate Advisor
Other advisors: Dr Kelvin Tuong, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of CD8+ T cells in the regression of squamous cell carcinoma
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor James Wells
-
2017
Doctor Philosophy
Uncovering novel regulators of CD8+ T-cell function in the skin
Associate Advisor
Other advisors: Associate Professor James Wells
-
2016
Doctor Philosophy
Evaluating CD8+ T-cell function in skin and squamous cell carcinoma following systemic suppression with rapamycin and tacrolimus.
Associate Advisor
Other advisors: Professor Fiona Simpson, Associate Professor James Wells
-
2015
Doctor Philosophy
Characterisation of RP105's divergent functions in macrophage responses to mycobacteria and LPS
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2015
Doctor Philosophy
Contributions of Wnt signalling to immune responses during acute bacterial infection
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2011
Doctor Philosophy
The effects of the balance of Type I and Type II NKT cells on CD8 T cells and Tumour Therapy
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
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2008
Doctor Philosophy
Interactions among Control Beliefs, Illness Severity, Biological Factors and a Psychological Preparation for Heart Surgery: Predictors of Health Outcomes
Associate Advisor
Other advisors: Emeritus Professor Kenneth Pakenham
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2007
Doctor Philosophy
Treatment of Cervical Cancer using RNA-Interference Against Human Papillomavirus Oncogenes
Associate Advisor
-
2005
Doctor Philosophy
Regulation of squamous differentiation by the E2F family transcription factors
Associate Advisor
-
2003
Doctor Philosophy
DENDRITIC CELL IMMUNOTHERAPY BASED ON HUMAN PAPILLOMAVIRUS
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
2003
Doctor Philosophy
THE ROLE OF AP2 IN SQUAMOUS DIFFERENTIATION
Associate Advisor
-
2003
Doctor Philosophy
IDENTIFICATION AND CLONING OF GENES ASSOCIATED WITH SQUAMOUS CELL CARCINOMA IN HUMAN SKIN TUMOURS
Associate Advisor
-
Doctor Philosophy
Peripheral Mechanisms of CD8+ T Cell Tolerance in H-2b K14E7 Transgenic Mice
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
Media
Enquiries
Contact Professor Ian Frazer directly for media enquiries about:
- Allergy
- Autoimmune disease
- Cancer - immunity
- Cancer - vaccines to prevent
- Cervical cancer vaccine
- Education - medical
- Genital wart virus disease
- Host-virus interactions
- Immunity
- Immunodeficiency
- Immunology
- Medical education
- Papillomavirus vaccines
- Pathology
- Transplantation immunology
- Tumour immunology
- Tumour vaccines
- Vaccines
- Viral infection
- Viral vaccines
- Viruses
- Warts - genital
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