
Overview
Background
Professor Ian Frazer is a clinician scientist, trained as a clinical immunologist in Scotland. As a professor at the University of Queensland, he leads a research group working at TRI in Brisbane, Australia on the immunobiology of epithelial cancers. He is recognised as co-inventor of the technology enabling the HPV vaccines, currently used worldwide to help prevent cervical cancer. He heads a biotechnology company, Jingang Medicine (Aus) Pty Ltd, working on new vaccine technologies, and is a board member of several companies and not for profit organisations. He was the inaugural president of the Australian Academy of Health and Medical Sciences, and a member of the Australian National Science and Technology Council. He chairs the Australian Medical Research Advisory Board of the Medical Research Future Fund.
He was recognised as Australian of the Year in 2006. He was recipient of the Prime Ministers Prize for Science, and of the Balzan Prize, in 2008, and was elected Fellow of the Royal Society of London in 2012. He was appointed Companion of the Order of Australia in the Queen’s Birthday Honours list in 2013.
Availability
- Professor Ian Frazer is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor (Honours) of Science (Advanced), University of Edinburgh
- Bachelor of Medicine Surgery, University of Edinburgh
- Doctoral Diploma of Medicine, University of Melbourne
- Royal College of Pathologists of Australasia, Royal College of Pathologists of Australasia
- Royal College of Physicians of Edinburgh, Royal College of Physicians of Edinburgh
Works
Search Professor Ian Frazer’s works on UQ eSpace
2010
Journal Article
Cervical cancer vaccine development
Frazer, Ian H. (2010). Cervical cancer vaccine development. Sexual Health, 7 (3), 230-234. doi: 10.1071/SH09132
2009
Journal Article
Cortisol changes interact with the effects of a cognitive behavioural psychological preparation for surgery on 12-month outcomes for surgical heart patients
Shelley, Michael, Pakenham, Kenneth Ian and Frazer, Ian (2009). Cortisol changes interact with the effects of a cognitive behavioural psychological preparation for surgery on 12-month outcomes for surgical heart patients. Psychology & Health, 24 (10), 1139-1152. doi: 10.1080/08870440802126704
2009
Journal Article
Keratinocytes efficiently process endogenous antigens for cytotoxic T-cell mediated lysis
Zhou, F, Frazer, IH and Leggatt, GR (2009). Keratinocytes efficiently process endogenous antigens for cytotoxic T-cell mediated lysis. EXPERIMENTAL DERMATOLOGY, 18 (12), 1053-1059. doi: 10.1111/j.1600-0625.2009.00907.x
2009
Journal Article
Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin
Chen, Xianfeng, Prow, Tarl W., Crichton, Michael L., Jenkins, Derek W.K., Roberts, Michael S., Frazer, Ian H., Fernando, Germain J.P. and Kendall, Mark A.F. (2009). Dry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skin. Journal of Controlled Release, 139 (3), 212-220. doi: 10.1016/j.jconrel.2009.06.029
2009
Journal Article
Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte Volume
Ferreira, MAR, Hottenga, JJ, Warrington, NM, Medland, SE, Willemsen, G, Lawrence, RW, Gordon, S, de Geus, EJC, Henders, AK, Smit, JH, Campbell, MJ, Wallace, L, Evans, DM, Wright, MJ, Nyholt, DR, James, AL, Beilby, JP, Penninx, BW, Palmer, LJ, Frazer, IH, Montgomery, GW, Martin, NG and Boomsma, DI (2009). Sequence Variants in Three Loci Influence Monocyte Counts and Erythrocyte Volume. AMERICAN JOURNAL OF HUMAN GENETICS, 85 (5), 745-749. doi: 10.1016/j.ajhg.2009.10.005
2009
Journal Article
Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
Benyamin, B, Ferreira, MAR, Willemsen, G, Gordon, S, Middelberg, RPS, McEvoy, BP, Hottenga, JJ, Henders, AK, Campbell, MJ, Wallace, L, Frazer, IH, Heath, AC, de Geus, EJC, Nyholt, DR, Visscher, PM, Penninx, BW, Boomsma, DI, Martin, NG, Montgomery, GW and Whitfield, JB (2009). Common variants in TMPRSS6 are associated with iron status and erythrocyte volume. Nature Genetics, 41 (11), 1173-1175. doi: 10.1038/ng.456
2009
Journal Article
IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced host
Liu, Xiao Song, Leerberg, Joanne, MacDonald, Kelli, Leggatt, Graham and Frazer, Ian (2009). IFN-gamma promotes generation of IL-10 secreting CD4+ T cells that suppress generation of CD8 responses in an antigen-experienced host. The Jounral of Immunology, 183 (1), 51-58. doi: 10.4049/jimmunol.0802047
2009
Journal Article
Interaction of human papillomaviruses with the host immune system: A well evolved relationship
Frazer, Ian (2009). Interaction of human papillomaviruses with the host immune system: A well evolved relationship. Virology, 384 (2), 410-414. doi: 10.1016/j.virol.2008.10.004
2009
Journal Article
Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4(+)CD25(+) T cells
Narayan, S., Choyce, A., Linedale, R., Saunders, N. A., Dahler, A., Chan, E., Fernando, G. J., Frazer, I. H. and Leggatt, G. R. (2009). Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4(+)CD25(+) T cells. European Journal of Immunology, 39 (2), 481-490. doi: 10.1002/eji.200838527
2009
Book Chapter
Vaccines against human papillomavirus infection
Frazer, Ian H. (2009). Vaccines against human papillomavirus infection. Vaccines against human papillomavirus infection. (pp. 977-986) edited by Levine, M. M. United States: Informa Healthcare.
2009
Conference Publication
A phase 1b multicentre study of HPV6 L1 virus-like particles as adjunct immunotherapy for anogenital warts
Jardine, D., Lu, J., Palmer, C., Pang, J., Chuah, J. and Frazer, I. (2009). A phase 1b multicentre study of HPV6 L1 virus-like particles as adjunct immunotherapy for anogenital warts. Australasian Sexual Health Conference 2009, Gold Coast, Queensland, Australia, 7 - 9 September 2009. COLLINGWOOD: CSIRO Publishing.
2009
Conference Publication
Immunotherapy for skin cancer
Leggatt, G. R., Zhong, J., Mattarollo, S., Liu, X., De Kluyver, R., Fiorenza, S., Zhou, J., Hadis, U., Warif, N. A., Rahimpour, A., Broom, J. and Frazer, I. H. (2009). Immunotherapy for skin cancer. 6th Annual Scientific Meeting, Australasian Society for Dermatology Research, Surfers Paradise, QLD, Australia, 20-21 May 2009. Baltimore, MD, U.S.A.: Nature Publishing Group. doi: 10.1038/jid.2009.333
2009
Book Chapter
Antigen recognition and self–non-self discrimination
Frazer, Ian H. (2009). Antigen recognition and self–non-self discrimination. Autoimmune neurological disease. (pp. 1-13) edited by Michael P. Pender and Pamela A. McCombe. Cambridge, United Kingdom: Cambridge University Press. doi: 10.1017/cbo9780511526916.002
2009
Conference Publication
A novel Nanopatch that directly delivers influenza vaccine painlessly to antigen presenting cells in the skin and affords high dose reduction
Fernando, Germain J. P., Chen, XianFeng, Prow, Tarl, Crichton, Michael, Frazer, Ian H., Brown, Lorena E. and Kendall, Mark A. F. (2009). A novel Nanopatch that directly delivers influenza vaccine painlessly to antigen presenting cells in the skin and affords high dose reduction. Third International Conference on Modern Vaccines Adjuvants & Delivery Systems, Vienna, Austria, 28-30 October 2009.
2009
Conference Publication
Fossilised knowledge? Libraries as repositories of knowledge in biomedical research in the cyberspace era
Frazer, Ian H. (2009). Fossilised knowledge? Libraries as repositories of knowledge in biomedical research in the cyberspace era. Positioning the Profession: the Tenth International Congress on Medical Librarianship, Brisbane, Australia, August 31-September 4, 2009.
2009
Conference Publication
Controlling Hpv Associated Disease: a Glass Half Full?
Frazer, I. (2009). Controlling Hpv Associated Disease: a Glass Half Full?. COLLINGWOOD: CSIRO PUBLISHING.
2008
Journal Article
Up-regulated expression of Sp1 protein coincident with a viral protein in human and mouse differentiating keratinocytes may act as a cell differentiation marker
Li, Bo, Wang, Xiao, Zhou, Fang, Saunders, Nicholas A., Frazer, Ian H. and Zhao, Kong-Nan (2008). Up-regulated expression of Sp1 protein coincident with a viral protein in human and mouse differentiating keratinocytes may act as a cell differentiation marker. Differentiation, 76 (10), 1068-1080. doi: 10.1111/j.1432-0436.2008.00300.x
2008
Journal Article
Autoimmunity and persistent viral infection: Two sides of the same coin?
Frazer, Ian (2008). Autoimmunity and persistent viral infection: Two sides of the same coin?. Journal of Autoimmunity, 31 (3), 216-218. doi: 10.1016/j.jaut.2008.04.014
2008
Conference Publication
The need for public education on HPV and cervical cancer prevention in Asia. Opinions of experts at the AOGIN Conference
Garland, S., Park, S. N., Ngan, H. Y S, Frazer, I., Tay, E. H., Chen, C. J., Bhatla, N., Pitts, M., Shin, H. R., Konno, R., Smith, J., Pagliusi, S. and Park, J. S. (2008). The need for public education on HPV and cervical cancer prevention in Asia. Opinions of experts at the AOGIN Conference. doi: 10.1016/j.vaccine.2008.07.077
2008
Journal Article
The need for public education on HPV and cervical cancer prevention in Asia: Opinions of experts at the AOGIN Conference
Garland, S., Park, S. N., Ngan, H. Y. S., Frazer, I., Tay, E. H., Chen, C. J., Bhatla, N., Pitts, M., Shin, H. R., Konno, R., Smith, J., Pagliusi, S. and Park, J. S. (2008). The need for public education on HPV and cervical cancer prevention in Asia: Opinions of experts at the AOGIN Conference. Vaccine, 26 (43), 5435-5440. doi: 10.1016/j.vaccine.2008.07.077
Funding
Current funding
Past funding
Supervision
Availability
- Professor Ian Frazer is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
Doctor Philosophy
The role of IL34 in HPV-mediated epithelial cancers
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Professor David Hume, Dr Janin Chandra
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
-
Doctor Philosophy
Spatial Multi-Omics Analysis of HPV-Positive Head and Neck Cancer: Tumour Oncogenesis and Discovery of Targeted Therapies
Associate Advisor
Other advisors: Dr Quan Nguyen, Associate Professor James Wells, Dr Jazmina Gonzalez Cruz
-
Doctor Philosophy
Assessment of predictors of response to checkpoint blockades in cancer patients.
Associate Advisor
Other advisors: Dr Ahmed Mehdi, Dr Janin Chandra, Dr Bree Tillett
Completed supervision
-
2024
Doctor Philosophy
The Role of Bacterially Induced Inflammation in Squamous Cell Carcinoma Development
Principal Advisor
Other advisors: Professor Phil Hugenholtz, Professor Mark Morrison, Dr Debottam Sinha, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of the skin microbiota in cutaneous squamous cell carcinoma
Principal Advisor
Other advisors: Professor Mark Morrison
-
2020
Doctor Philosophy
Modulation of Immune Responses by HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt, Dr Janin Chandra
-
2018
Doctor Philosophy
Association of Local Immune Suppression in Skin with HPV-Induced Epithelial Hyperplasia
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2017
Master Philosophy
Aetiology of Oral Cavity Squamous Cell Carcinoma - An Exploration utilising Next Generation Sequencing
Principal Advisor
-
2015
Doctor Philosophy
Mechanisms of 2,4-Dinitrochlorobenzene-induced acute inflammation in Human Papillomavirus type 16 E7 oncoprotein expressing skin
Principal Advisor
-
2014
Doctor Philosophy
Mechanisms of immunoregulation in human papillomavirus-associated epithelial hyperplasia: of mice and (wo)men
Principal Advisor
Other advisors: Professor Antje Blumenthal
-
2013
Doctor Philosophy
LANGERHANS CELLS IN SKIN EXPRESSING HUMAN PAPILLOMAVIRUS TYPE 16 E7
Principal Advisor
-
2010
Doctor Philosophy
CD4+ T cells provide help to CD8+ T cells in immune recall responses in skin
Principal Advisor
-
2010
Doctor Philosophy
Augmenting CD8+ T cell-mediated cutaneous immunotherapy in a murine model system
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2010
Doctor Philosophy
Role of dendritic epidermal T cells in skin graft rejection
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2009
Doctor Philosophy
Human Papillomavirus 16 E7 Inhibits the ability of IFN-γ in Enhancement of MHC Class I Antigen Presentation and CTL Lysis by Affecting IRF-1 Expression in Keratinocytes
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
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2008
Doctor Philosophy
Studies on mechanisms of skin graft rejection
Principal Advisor
Other advisors: Honorary Professor Geoffrey Hill
-
2003
Doctor Philosophy
IMMUNE RESPONSE TO PAPILLOMAVIRUS INFECTION
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
-
2002
Doctor Philosophy
DETERMINING CTL CHARACTERISTICS WHICH CORRELATE WITH TUMOUR REGRESSION IN VIVO
Principal Advisor
Other advisors: Associate Professor Graham Leggatt
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2023
Doctor Philosophy
Local Delivery Of Immunotherapeutic Antibodies To Skin Cancers
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor Graham Leggatt
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2022
Doctor Philosophy
Understanding CD4+ T cell responses to HPV16 E7 antigen in a mouse model of precancerous skin
Associate Advisor
Other advisors: Dr Kelvin Tuong, Dr Janin Chandra
-
2021
Doctor Philosophy
The role of CD8+ T cells in the regression of squamous cell carcinoma
Associate Advisor
Other advisors: Dr Jazmina Gonzalez Cruz, Associate Professor James Wells
-
2017
Doctor Philosophy
Uncovering novel regulators of CD8+ T-cell function in the skin
Associate Advisor
Other advisors: Associate Professor James Wells
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2016
Doctor Philosophy
Evaluating CD8+ T-cell function in skin and squamous cell carcinoma following systemic suppression with rapamycin and tacrolimus.
Associate Advisor
Other advisors: Professor Fiona Simpson, Associate Professor James Wells
-
2015
Doctor Philosophy
Characterisation of RP105's divergent functions in macrophage responses to mycobacteria and LPS
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2015
Doctor Philosophy
Contributions of Wnt signalling to immune responses during acute bacterial infection
Associate Advisor
Other advisors: Professor Antje Blumenthal
-
2011
Doctor Philosophy
The effects of the balance of Type I and Type II NKT cells on CD8 T cells and Tumour Therapy
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
-
2008
Doctor Philosophy
Interactions among Control Beliefs, Illness Severity, Biological Factors and a Psychological Preparation for Heart Surgery: Predictors of Health Outcomes
Associate Advisor
Other advisors: Emeritus Professor Kenneth Pakenham
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2007
Doctor Philosophy
Treatment of Cervical Cancer using RNA-Interference Against Human Papillomavirus Oncogenes
Associate Advisor
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2005
Doctor Philosophy
Regulation of squamous differentiation by the E2F family transcription factors
Associate Advisor
-
2003
Doctor Philosophy
DENDRITIC CELL IMMUNOTHERAPY BASED ON HUMAN PAPILLOMAVIRUS
Associate Advisor
Other advisors: Professor Ranjeny Thomas
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2003
Doctor Philosophy
IDENTIFICATION AND CLONING OF GENES ASSOCIATED WITH SQUAMOUS CELL CARCINOMA IN HUMAN SKIN TUMOURS
Associate Advisor
-
2003
Doctor Philosophy
THE ROLE OF AP2 IN SQUAMOUS DIFFERENTIATION
Associate Advisor
-
Doctor Philosophy
Peripheral Mechanisms of CD8+ T Cell Tolerance in H-2b K14E7 Transgenic Mice
Associate Advisor
Other advisors: Associate Professor Graham Leggatt
Media
Enquiries
Contact Professor Ian Frazer directly for media enquiries about:
- Allergy
- Autoimmune disease
- Cancer - immunity
- Cancer - vaccines to prevent
- Cervical cancer vaccine
- Education - medical
- Genital wart virus disease
- Host-virus interactions
- Immunity
- Immunodeficiency
- Immunology
- Medical education
- Papillomavirus vaccines
- Pathology
- Transplantation immunology
- Tumour immunology
- Tumour vaccines
- Vaccines
- Viral infection
- Viral vaccines
- Viruses
- Warts - genital
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